Standout Papers
- The possibilities and prospects of obtaining high-resolution information (below 30 Å) on biological material using the electron microscope (1974)
- Comparisons and physics basis of tokamak transport models and turbulence simulations (2000)
- Transactivation of miR-34a by p53 Broadly Influences Gene Expression and Promotes Apoptosis (2007)
Citation Impact
Citing Papers
Development of a Lung Cancer Therapeutic Based on the Tumor Suppressor MicroRNA-34
2010
p53-Responsive MicroRNAs 192 and 215 Are Capable of Inducing Cell Cycle Arrest
2008
Nutlin-3a Activates p53 to Both Down-regulate Inhibitor of Growth 2 and Up-regulate mir-34a, mir-34b, and mir-34c Expression, and Induce Senescence
2008
Restitution of Tumor Suppressor MicroRNAs Using a Systemic Nanovector Inhibits Pancreatic Cancer Growth in Mice
2011
miRNA-34 Prevents Cancer Initiation and Progression in a Therapeutically Resistant K-ras and p53-Induced Mouse Model of Lung Adenocarcinoma
2012
Local DNA Topography Correlates with Functional Noncoding Regions of the Human Genome
2009 Science
Crystal structure of a replication fork single-stranded DNA binding protein (T4 gp32) complexed to DNA
1995 StandoutNatureNobel
Comprehensive molecular portraits of human breast tumours
2012 StandoutNature
MicroRNA dysregulation in cancer: diagnostics, monitoring and therapeutics. A comprehensive review
2012
Hallmarks of Cancer: The Next Generation
2011 Standout
p53‐repressed miRNAs are involved with E2F in a feed‐forward loop promoting proliferation
2008
An integrated encyclopedia of DNA elements in the human genome
2012 StandoutNature
Avocado: a multi-scale deep tensor factorization method learns a latent representation of the human epigenome
2020
Ultra-thin epitaxial films of graphite and hexagonal boron nitride on solid surfaces
1997
HIV-1 rev regulation involves recognition of non-Watson-Crick base pairs in viral RNA
1991 StandoutNobel
RIM Proteins Tether Ca2+ Channels to Presynaptic Active Zones via a Direct PDZ-Domain Interaction
2011 StandoutNobel
Deep learning: new computational modelling techniques for genomics
2019
MiR-34a inhibits proliferation and migration of breast cancer through down-regulation of Bcl-2 and SIRT1
2012
MYC on the Path to Cancer
2012 Standout
Predicting effects of noncoding variants with deep learning–based sequence model
2015
Therapeutic microRNA Delivery Suppresses Tumorigenesis in a Murine Liver Cancer Model
2009
Influence of Metabolism on Epigenetics and Disease
2013 StandoutNobel
Ap endonucleases and dna glycosylases that recognize oxidative dna damage
1988
Base-resolution models of transcription-factor binding reveal soft motif syntax
2021
Targeting microRNAs in cancer: rationale, strategies and challenges
2010
Cross-species regulatory sequence activity prediction
2020
A conserved secondary structure for telomerase RNA
1991 StandoutNobel
Instability and decay of the primary structure of DNA
1993 StandoutNatureNobel
PDL1 Regulation by p53 via miR-34
2015
Basset: learning the regulatory code of the accessible genome with deep convolutional neural networks
2016
Effective gene expression prediction from sequence by integrating long-range interactions
2021 StandoutNobel
Detecting genome-wide directional effects of transcription factor binding on polygenic disease risk
2018
Saturation mutagenesis of twenty disease-associated regulatory elements at single base-pair resolution
2019
A Whole-Genome Analysis Framework for Effective Identification of Pathogenic Regulatory Variants in Mendelian Disease
2016
Blinded by the Light: The Growing Complexity of p53
2009 Standout
Cell-Type Independent MYC Target Genes Reveal a Primordial Signature Involved in Biomass Accumulation
2011
A positive feedback between p53 and miR-34 miRNAs mediates tumor suppression
2014
Secondary Structure of Vertebrate Telomerase RNA
2000 StandoutNobel
Sequential regulatory activity prediction across chromosomes with convolutional neural networks
2018
Systemic Delivery of Tumor Suppressor microRNA Mimics Using a Neutral Lipid Emulsion Inhibits Lung Tumors in Mice
2011
The microRNA miR-34a inhibits prostate cancer stem cells and metastasis by directly repressing CD44
2011
MicroRNA biogenesis pathways in cancer
2015 Standout
Somatic mutations in DROSHA and DICER1 impair microRNA biogenesis through distinct mechanisms in Wilms tumours
2014
MicroRNA therapeutics: towards a new era for the management of cancer and other diseases
2017 Standout
Transcriptional regulatory code of a eukaryotic genome
2004 StandoutNature
Integrase-mediated spacer acquisition during CRISPR–Cas adaptive immunity
2015 StandoutNatureNobel
miR-34 – a microRNA replacement therapy is headed to the clinic
2012
Local Supercoil-Stabilized DNA Structure
1991
Noncanonical DNA Motifs as Transactivation Targets by Wild Type and Mutant p53
2008
A roadmap for graphene
2012 StandoutNatureNobel
Deep learning sequence-based ab initio prediction of variant effects on expression and disease risk
2018
Creating monolayers and thin films of a novel bis(alkyl) substituted asymmetrical polyoxotungstate, {[CH3(CH2)11Si]2OSiW11O39}4−using the Langmuir–Blodgett technique
2003
Development of micro RNA therapeutics is coming of age
2014
Scrapie prions aggregate to form amyloid-like birefringent rods
1983 StandoutNobel
CADD: predicting the deleteriousness of variants throughout the human genome
2018 Standout
New Routes for Multiple Derivatization of Polyoxometalates. Bis(acetato)dirhodium-11-tungstophosphate, [(PO4)W11O35{Rh2(OAc)2}]5-
1997
Characterization by electron microscopy of the complex formed between T4 bacteriophage gene 32-protein and DNA
1972
Inference of patient-specific pathway activities from multi-dimensional cancer genomics data using PARADIGM
2010
Secondary structure of the circular form of the Tetrahymena rRNA intervening sequence: a technique for RNA structure analysis using chemical probes and reverse transcriptase.
1985 StandoutNobel
Metal(II) ion catalyzed transphosphorylation of four homodinucleotides and five pairs of dinucleotide sequence isomers
1974
Rhodium−Carbon Bond Formation in Aqueous Solution. Synthesis, Structure, and Reactivity of the Functionalized Heteropolytungstates, [XW11O39RhCH2COOH]5,6- (X = P, Si)
1998
Envelope structure of Semliki Forest virus reconstructed from cryo-electron micrographs
1986 StandoutNatureNobel
Local denaturation of DNA by shearing forces and by heat
1963 StandoutNobel
Graphene photonics and optoelectronics
2010 Standout
The in vitro transcription units of bacteriophage φX174
1976
Autocatalytic cyclization of an excised intervening sequence RNA is a cleavage–ligation reaction
1983 StandoutNatureNobel
Use of polylysine for adsorption of nuclei acids and enzymes to electron microscope specimen films.
1977
Beam damage to organic material is considerably reduced in cryo-electron microscopy
1980 StandoutNobel
The Chemical Modification of Nucleic Acids
1969
A Study on Heavy/Light Atom Discrimination in Bright-Field Electron Microscopy Using the Computer
1972 StandoutNobel
Some progress in the use of a scanning transmission electron microscope for the observation of biomacromolecules
1976 StandoutNobel
Lengths and patterns of transcriptional units in the amplified nucleoli of oocytes of Xenopus laevis
1977
Detailed analysis of the higher-order structure of 16S-like ribosomal ribonucleic acids
1983
miR-34a repression of SIRT1 regulates apoptosis
2008
The role of DNA rearrangement and alternative RNA processing in the expression of immunoglobulin delta genes
1981 StandoutNobel
Oxidative Nucleobase Modifications Leading to Strand Scission
1998 Standout
Carbon loss during irradiation of T4 bacteriophages and E. coli bacteria in electron microscopes
1975 StandoutNobel
Nucleosome Arcs and Helices
1978 StandoutScienceNobel
Chirality in Polyoxometalate Chemistry
2008
Immunocytochemical visualization of coated pits and vesicles in human fibroblasts: Relation to low density lipoprotein receptor distribution
1978 StandoutNobel
Computer Averaging of Electron Micrographs of 40 S Ribosomal Subunits
1981 StandoutScienceNobel
DNA Electron Microscopy - Part
1981
Cytochemistry of Synapses: Selective Staining for Electron Microscopy
1966 Science
Main-Group Element, Organic, and Organometallic Derivatives of Polyoxometalates
1998
The Chemistry of Self-Splicing RNA and RNA Enzymes
1987 StandoutScienceNobel
Graphene: Status and Prospects
2009 StandoutScienceNobel
Combinatorial Action of MicroRNAs let-7 and miR-34 Effectively Synergizes with Erlotinib to Suppress Non-small Cell Lung Cancer Cell Proliferation
2015
Hybrid Organic−Inorganic Polyoxometalate Compounds: From Structural Diversity to Applications
2010 Standout
Chemotherapy induces enrichment of CD47 + /CD73 + /PDL1 + immune evasive triple-negative breast cancer cells
2018 StandoutNobel
Specific interaction between the self-splicing RNA of Tetrahymena and its guanosine substrate: implications for biological catalysis by RNA
1984 StandoutNatureNobel
Reversible Chemical Modification of the Scrapie Agent
1981 StandoutScienceNobel
Predicted alpha-helical regions of the prion protein when synthesized as peptides form amyloid.
1992 StandoutNobel
Role of the coated endocytic vesicle in the uptake of receptor-bound low density lipoprotein in human fibroblasts
1977 StandoutNobel
Image Analysis In Electron Microscopy
1979 StandoutNobel
THF EARLY STAGES OF ABSORPTION OF INJECTED HORSERADISH PEROXIDASE IN THE PROXIMAL TUBULES OF MOUSE KIDNEY: ULTRASTRUCTURAL CYTOCHEMISTRY BY A NEW TECHNIQUE
1966 Standout
Secondary Structure of 16 S Ribosomal RNA
1981 Science
Transcription of cloned Xenopus ribosomal genes visualised after injection into oocyte nuclei
1978 StandoutNatureNobel
Carbon Powder and Fiber-Supported Polyoxometalate Catalytic Materials. Preparation, Characterization, and Catalytic Oxidation of Dialkyl Sulfides as Mustard (HD) Analogues
1996 StandoutNobel
Tumor-suppressive miR-34a induces senescence-like growth arrest through modulation of the E2F pathway in human colon cancer cells
2007
The reconstruction of structure from electron micrographs of randomly oriented particles
1980
Three abundance classes in HeLa cell messenger RNA
1974 StandoutNatureNobel
Averaging of low exposure electron micrographs of non-periodic objects
1975 StandoutNobel
Mono- and di-functional aromatic amines with p-alkoxy substituents as novel arylimido ligands for the hexamolybdate ion
2003
Visualization of Nucleolar Genes
1969 Science
Nucleotide composition of short segments of DNA molecules
1965
Analysis of transcriptional regulatory signals of the HSV thymidine kinase gene: Identification of an upstream control region
1981 StandoutNobel
Promotion of direct reprogramming by transformation-deficient Myc
2010 StandoutNobel
Genetic effects of thymine glycol: site-specific mutagenesis and molecular modeling studies.
1989
Heteropolytungstates containing organotin and cobalt or zinc atoms
1997
The Structure of Ribosomal RNA and Its Organization Relative to Ribosomal Protein
1983
A Complete Mapping of the Proteins in the Small Ribosomal Subunit of Escherichia coli
1987 StandoutScienceNobel
Preliminary measurements of uranium atom motion on corbon films at low temperatures
1978
Accurate proteome-wide missense variant effect prediction with AlphaMissense
2023 StandoutScienceNobel
Femtosecond dynamics of DNA-mediated electron transfer
1999 StandoutNobel
The electronic properties of graphene
2009 StandoutNobel
Nucleotide sequence of bacteriophage φX174 DNA
1977 StandoutNatureNobel
Works of M Beer being referenced
Discriminative prediction of mammalian enhancers from DNA sequence
2011
Enhanced Regulatory Sequence Prediction Using Gapped k-mer Features
2014
Predicting Gene Expression from Sequence
2004
Transactivation of miR-34a by p53 Broadly Influences Gene Expression and Promotes Apoptosis
2007 Standout
Local epigenomic state cannot discriminate interacting and non-interacting enhancer–promoter pairs with high accuracy
2018
A method to predict the impact of regulatory variants from DNA sequence
2015
Metrics of sequence constraint overlook regulatory sequences in an exhaustive analysis at phox2b
2007
Pyrolytic Formation of Highly Crystalline Graphite Films
1966
ELECTRON STAINS
1961
The Use of Heavy Metal Salts as Electron Stains
1965
Functionalized heteropolytungstate anions possessing a modified Dawson structure: small, individually distinguishable labels for conventional transmission electron microscopy
1985
Molecular microscopy of labeled polynucleotides: Stability of osmium atoms
1977
Electron-microscopic localization of the binding of Escherichia coli RNA polymerase to T7 DNA in vitro
1972
An electromicroscopic study of extended single polynucleotide chains
1963
DETERMINATION OF BASE SEQUENCE IN NUCLEIC ACIDS WIT THE ELECTRON MICROSCOPE: VISIBILITY OF A MARKER
1962
Electron stains II: Electron microscopic studies on the visibility of stained DNA molecules
1961
Osmium-labeled polynucleotides. The reaction of osmium tetroxide with deoxyribonucleic acid and synthetic polynucleotides in the presence of tertiary nitrogen donor ligands
1977
Determination of Base Sequence in Nucleic Acids with the Electron Microscope. IV. Nucleoside Complexes with Certain Metal Ions*
1965
New methods for the preparation of nucleic acid molecules for electron microscopy
1969
Electron microscopic determination of the binding sites of ribosomal proteins S4 and S8 on 16S RNA.
1978
Autocorrelation Functions of Noisy Electron Micrographs of Stained Polynucleotide Chains
1968 Science
The electron microscopy of phage DNA molecules with denatured regions
1961
Determination of Base Sequence in Nucleic Acids with the Electron Microscope. V. The Thymine-Specific Reactions of Osmium Tetroxide with Deoxyribonucleic Acid and Its Components*
1966
Lin-28B transactivation is necessary for Myc-mediated let-7 repression and proliferation
2009
The possibilities and prospects of obtaining high-resolution information (below 30 Å) on biological material using the electron microscope
1974 StandoutNobel
Whole-Genome Discovery of Transcription Factor Binding Sites by Network-Level Conservation
2003
BASE SEQUENCE DETERMINATION IN NUCLEIC ACIDS WITH THE ELECTRON MICROSCOPE, III. CHEMISTRY AND MICROSCOPY OF GUANINE-LABELED DNA
1965
gkmSVM: an R package for gapped-kmer SVM
2016