Citation Impact
Citing Papers
HIFα Targeted for VHL-Mediated Destruction by Proline Hydroxylation: Implications for O 2 Sensing
2001 StandoutScienceNobel
High-Resolution Crystal Structure of an Engineered Human β 2 -Adrenergic G Protein–Coupled Receptor
2007 StandoutScienceNobel
Piezo1 and Piezo2 Are Essential Components of Distinct Mechanically Activated Cation Channels
2010 StandoutScienceNobel
Keeping G Proteins at Bay: A Complex Between G Protein-Coupled Receptor Kinase 2 and Gßγ
2003 StandoutScienceNobel
A Sulfilimine Bond Identified in Collagen IV
2009 StandoutScienceNobel
Targeting of Cyclic AMP Degradation to β 2 -Adrenergic Receptors by β-Arrestins
2002 StandoutScienceNobel
PDE4 cAMP-specific phosphodiesterases
2001
The RACK1 Signaling Scaffold Protein Selectively Interacts with the cAMP-specific Phosphodiesterase PDE4D5 Isoform
1999
Histone-like TAFs within the PCAF Histone Acetylase Complex
1998
EGL-10 Regulates G Protein Signaling in the C. elegans Nervous System and Shares a Conserved Domain with Many Mammalian Proteins
1996 StandoutNobel
The SREBP Pathway: Regulation of Cholesterol Metabolism by Proteolysis of a Membrane-Bound Transcription Factor
1997 StandoutNobel
The atomic structure of protein-protein recognition sites 1 1Edited by A. R. Fersht
1999 Standout
Multisite phosphorylation of a CDK inhibitor sets a threshold for the onset of DNA replication
2001 Nature
Twenty-Five Years of the Nucleosome, Fundamental Particle of the Eukaryote Chromosome
1999 StandoutNobel
Apaf-1, a Human Protein Homologous to C. elegans CED-4, Participates in Cytochrome c–Dependent Activation of Caspase-3
1997 Standout
High-resolution crystal structure of human protease-activated receptor 1
2012 StandoutNatureNobel
The Coiled-coil Region of the G Protein β Subunit
1997
A Complex of Cdc4p, Skp1p, and Cdc53p/Cullin Catalyzes Ubiquitination of the Phosphorylated CDK Inhibitor Sic1p
1997
How chromatin-binding modules interpret histone modifications: lessons from professional pocket pickers
2007
The road to fully programmable protein catalysis
2022 StandoutNatureNobel
Degradation of Cdc25A by β-TrCP during S phase and in response to DNA damage
2003 StandoutNatureNobel
Telomere Shortening and Tumor Formation by Mouse Cells Lacking Telomerase RNA
1997 StandoutNobel
Structural Basis of Inward Rectification
2002 StandoutNobel
C-terminal Mutation of G Protein β Subunit Affects Differentially Extracellular Signal-regulated Kinase and c-Jun N-terminal Kinase Pathways in Human Embryonal Kidney 293 Cells
1997
Eater, a Transmembrane Protein Mediating Phagocytosis of Bacterial Pathogens in Drosophila
2005 StandoutNobel
Receptor-Mediated Activation of Heterotrimeric G-Proteins: Current Structural Insights
2007
Interaction Sites of the G Protein β Subunit with Brain G Protein-coupled Inward Rectifier K+ Channel
2001
Conformational changes in the G protein Gs induced by the β2 adrenergic receptor
2011 StandoutNatureNobel
The C. elegans Protein EGL-1 Is Required for Programmed Cell Death and Interacts with the Bcl-2–like Protein CED-9
1998 StandoutNobel
Crystal structure of the β2 adrenergic receptor–Gs protein complex
2011 StandoutNatureNobel
Sites for Gα Binding on the G Protein β Subunit Overlap with Sites for Regulation of Phospholipase Cβ and Adenylyl Cyclase
1998 Nobel
Genome-wide RNAi analysis of Caenorhabditis elegans fat regulatory genes
2003 StandoutNatureNobel
G Protein Heterodimers: New Structures Propel New Questions
1996
Phosducin induces a structural change in transducin βγ
1998
Oncogenic Mutations Counteract Intrinsic Disorder in the EGFR Kinase and Promote Receptor Dimerization
2012 StandoutNobel
TRPV1 structures in distinct conformations reveal activation mechanisms
2013 StandoutNatureNobel
Heterotrimeric G proteins
1996
Cytochrome c and dATP-Dependent Formation of Apaf-1/Caspase-9 Complex Initiates an Apoptotic Protease Cascade
1997 Standout
Metallic-Type Oscillatory Interlayer Exchange Coupling across an Epitaxial FeSi Spacer
2001 StandoutNobel
Suppression of inflammation by a synthetic histone mimic
2010 StandoutNatureNobel
Mechanism of the receptor-catalyzed activation of heterotrimeric G proteins
2006
Constitutively active and G-protein coupled inward rectifier K+ channels: Kir2.0 and Kir3.0
2007
Processing of Bulk Metallic Glass
2009 Standout
The Second Intracellular Loop of the m5 Muscarinic Receptor Is the Switch Which Enables G-protein Coupling
1998
Crystal structure of the µ-opioid receptor bound to a morphinan antagonist
2012 StandoutNatureNobel
Crystal Structure at 2.4 Å Resolution of the Complex of Transducin βγ and Its Regulator, Phosducin
1996
Heterotrimeric G protein activation by G-protein-coupled receptors
2007
Seven-transmembrane-spanning receptors and heart function
2002 StandoutNatureNobel
Structure of a β1-adrenergic G-protein-coupled receptor
2008 StandoutNatureNobel
Structure of a β-TrCP1-Skp1-β-Catenin Complex
2003
A Domain on the G Protein β Subunit Interacts with Both Adenylyl Cyclase 2 and the Muscarinic Atrial Potassium Channel
1996
Structure and dynamics of the M3 muscarinic acetylcholine receptor
2012 StandoutNatureNobel
X-ray structure of the mammalian GIRK2–βγ G-protein complex
2013 NatureNobel
MEP-1 and a Homolog of the NURD Complex Component Mi-2 Act Together to Maintain Germline-Soma Distinctions in C. elegans
2002 StandoutNobel
Integrins
2002 Standout
Sterol Resistance in CHO Cells Traced to Point Mutation in SREBP Cleavage–Activating Protein
1996 Nobel
lin-35 and lin-53, Two Genes that Antagonize a C. elegans Ras Pathway, Encode Proteins Similar to Rb and Its Binding Protein RbAp48
1998 StandoutNobel
TLP1: A Gene Encoding a Protein Component of Mammalian Telomerase Is a Novel Member of WD Repeats Family
1997
tea1 and the Microtubular Cytoskeleton Are Important for Generating Global Spatial Order within the Fission Yeast Cell
1997 StandoutNobel
Mutational Analysis of Gβγ and Phospholipid Interaction with G Protein-coupled Receptor Kinase 2
2000
Structure of RGS4 Bound to AlF4−-Activated Giα1: Stabilization of the Transition State for GTP Hydrolysis
1997 Nobel
C. elegans phagocytosis and cell-migration protein CED-5 is similar to human DOCK180
1998 StandoutNatureNobel
Enhanced antiferromagnetic exchange coupling in Fe/Si/Fe epitaxial trilayers with Fe0.5Si0.5 boundary layers
2002 StandoutNobel
Formation of a ferromagnetic silicide at the Fe/Si(100) interface
1997
Rbx1, a Component of the VHL Tumor Suppressor Complex and SCF Ubiquitin Ligase
1999 StandoutScienceNobel
A novel type of protein kinase phosphorylates actin in the actin-fragmin complex.
1996
Crystal Structure of the Extracellular Segment of Integrin αVβ3
2001 Science
Regulator of G Protein Signaling Proteins: Novel Multifunctional Drug Targets
2001
Temperature-dependent biquadratic coupling in antiferromagnetically coupled Fe/FeSi multilayers
1996
A proteolytic pathway that controls the cholesterol content of membranes, cells, and blood
1999 Nobel
SCF and Cullin/RING H2-Based Ubiquitin Ligases
1999
Folding of the N-terminal, ligand-binding region of integrin α-subunits into a β-propeller domain
1997
Layered magnetic structures in research and application
2000 StandoutNobel
The p55 Subunit of Drosophila Chromatin Assembly Factor 1 Is Homologous to a Histone Deacetylase-Associated Protein
1996
The Polycomb group in Caenorhabditis elegans and maternal control of germline development
1998
Microscopic environment of Fe in epitaxially stabilizedc − FeSi
1999
Interlayer coupling inF e / F e 1 − x Si x
1999
Very strong interlayer exchange coupling in epitaxial Fe/Fe1−xSix/Fe trilayers (x=0.4–1.0)
2002 StandoutNobel
Uncovering Molecular Mechanisms Involved in Activation of G Protein-Coupled Receptors
2000
Structure of the VHL-ElonginC-ElonginB Complex: Implications for VHL Tumor Suppressor Function
1999 StandoutScienceNobel
SIC1 is ubiquitinated in vitro by a pathway that requires CDC4, CDC34, and cyclin/CDK activities.
1997
Computational Modeling Approaches to Structure−Function Analysis of G Protein-Coupled Receptors
2005
Structure of an HIF-1α-pVHL Complex: Hydroxyproline Recognition in Signaling
2002 StandoutScienceNobel
G PROTEIN βγ SUBUNITS
1997
The Solution Structure and Dynamics of the Pleckstrin Homology Domain of G Protein-coupled Receptor Kinase 2 (β-Adrenergic Receptor Kinase 1)
1998
Exponential Dependence of the Interlayer Exchange Coupling on the Spacer Thickness in MBE-grown Fe/SiFe/Fe Sandwiches
1997
Formation of nonmagneticc − Fe 1 − x Si
1999
Interaction of a G protein with an activated receptor opens the interdomain interface in the alpha subunit
2011
Computational Design of Proteins Targeting the Conserved Stem Region of Influenza Hemagglutinin
2011 StandoutScienceNobel
Update 1 of: Computational Modeling Approaches to Structure–Function Analysis of G Protein-Coupled Receptors
2011
Enhancing Protein Stability with Genetically Encoded Noncanonical Amino Acids
2018
RNAi in C. elegans : Soaking in the Genome Sequence
1998 StandoutScienceNobel
GTPase-Activating Proteins for Heterotrimeric G Proteins: Regulators of G Protein Signaling (RGS) and RGS-Like Proteins
2000
Translocation of C. elegans CED-4 to Nuclear Membranes During Programmed Cell Death
2000 StandoutScienceNobel
Molecular Basis for Interactions of G Protein βγ Subunits with Effectors
1998 StandoutScienceNobel
G PROTEIN MECHANISMS: Insights from Structural Analysis
1997
G proteins, effectors and GAPs: structure and mechanism
1997
Structural flexibility of the Gαs α-helical domain in the β 2 -adrenoceptor Gs complex
2011 StandoutNobel
Crystal Structure of the Adenylyl Cyclase Activator G s α
1997 ScienceNobel
A Region of Adenylyl Cyclase 2 Critical for Regulation by G Protein βγ Subunits
1995 StandoutScienceNobel
Works of M. A. Wall being referenced
Structural basis of activity and subunit recognition in G protein heterotrimers
1998
The structure of the G protein heterotrimer Giα1β1γ2
1995 Nobel
Engineering Hyperthermostability into a GH11 Xylanase Is Mediated by Subtle Changes to Protein Structure
2008
The A326S Mutant of Giα1 as an Approximation of the Receptor-bound State
1998 Nobel
Structure and magnetism of Fe/Si multilayers grown by ion-beam sputtering
1996
A G protein γ subunit-like domain shared between RGS11 and other RGS proteins specifies binding to G β5 subunits
1998 Nobel
Crystallization of beryllium–boron metallic glasses
2003