Citation Impact
Citing Papers
( R )-2-Hydroxyglutarate Is Sufficient to Promote Leukemogenesis and Its Effects Are Reversible
2013 StandoutScienceNobel
The mystery of nonclassical protein secretion
2003
Establishment and characterization of a unique human cell line that proliferates dependently on GM‐CSF, IL‐3, or erythropoietin
1989
Dissection of TNF Receptor 1 Effector Functions: JNK Activation Is Not Linked to Apoptosis While NF-κB Activation Prevents Cell Death
1996 Standout
Activation of interleukin‐ 1β by a co‐induced protease
1989
Functional Characterization of the Human Interleukin-15 Receptor αChain and Close Linkage of IL15RA and IL2RA Genes
1995
FADD, a novel death domain-containing protein, interacts with the death domain of fas and initiates apoptosis
1995 Standout
Cleavage of poly(ADP-ribose) polymerase by a proteinase with properties like ICE
1994 StandoutNature
The C. elegans cell death gene ced-3 encodes a protein similar to mammalian interleukin-1β-converting enzyme
1993 Standout
Karyotype and in vitro-response to GM-CSF
1990
Cryopyrin activates the inflammasome in response to toxins and ATP
2006 StandoutNature
Apoptosis by Death Factor
1997 Standout
Inflammatory caspases and inflammasomes: master switches of inflammation
2006
Role of a Distal Enhancer Containing a Functional NF-κ B-binding Site in Lipopolysaccharide-induced Expression of a Novel α1-Antitrypsin Gene
1995
X-linked IAP is a direct inhibitor of cell-death proteases
1997 StandoutNature
A Prospective, Randomized Trial of Autologous Bone Marrow Transplantation and Chemotherapy in Multiple Myeloma
1996 Standout
Interleukin-1 and hematopoiesis
1989
The molecular control of cell division, differentiation commitment and maturation in haemopoietic cells
1989 StandoutNature
Coiled Coils Direct Assembly of a Cold-Activated TRP Channel
2006 StandoutNobel
NLRP3 is activated in Alzheimer’s disease and contributes to pathology in APP/PS1 mice
2012 StandoutNature
Effects of Recombinant Human Granulocyte–Macrophage Colony-Stimulating Factor in Patients with Myelodysplastic Syndromes
1987
Interleukin-1 and Cutaneous Inflammation: A Crucial Link Between Innate and Acquired Immunity
2000
Involvement of MACH, a Novel MORT1/FADD-Interacting Protease, in Fas/APO-1- and TNF Receptor–Induced Cell Death
1996 Standout
Dendritic cells from mouse bone marrow: In vitro differentiation using low doses of recombinant granulocyte-macrophage colony-stimulating factor
1992
Expression, purification and characterization of recombinant marine granulocyte-macrophage colony-stimulating factor and bovine interleukin-2 from yeast
1987
Interleukin‐1β, Interleukin‐18, and the Interleukin‐1β Converting Enzymea
1998
Immunity, Inflammation, and Cancer
2010 Standout
NF-κB Is a Negative Regulator of IL-1β Secretion as Revealed by Genetic and Pharmacological Inhibition of IKKβ
2007
Identification and inhibition of the ICE/CED-3 protease necessary for mammalian apoptosis
1995 StandoutNature
Ligation of CD40 Activates Interleukin 1β-converting Enzyme (Caspase-1) Activity in Vascular Smooth Muscle and Endothelial Cells and Promotes Elaboration of Active Interleukin 1β
1997
Caenorhabditis elegans CED-9 protein is a bifunctional cell-death inhibitor
1997 StandoutNatureNobel
Yama/CPP32β, a mammalian homolog of CED-3, is a CrmA-inhibitable protease that cleaves the death substrate poly(ADP-ribose) polymerase
1995 Standout
Differential activation of the inflammasome by caspase-1 adaptors ASC and Ipaf
2004 StandoutNature
FLICE, A Novel FADD-Homologous ICE/CED-3–like Protease, Is Recruited to the CD95 (Fas/APO-1) Death-Inducing Signaling Complex
1996 Standout
Non-canonical inflammasome activation targets caspase-11
2011 StandoutNature
Atherosclerosis — An Inflammatory Disease
1999 Standout
Continuous activation of primitive hematopoietic cells in long‐term human marrow cultures containing irradiated tumor cells
1991
Clonal selection and learning in the antibody system
1996 StandoutNature
The Inflammasomes
2010 Standout
Interleukin 1: the first interleukin
1990
Mice deficient in IL-1β-converting enzyme are defective in production of mature IL-1β and resistant to endotoxic shock
1995
Protection against a lethal dose of endotoxin by an inhibitor of tumour necrosis factor processing
1994 Nature
A metalloproteinase disintegrin that releases tumour-necrosis factor-α from cells
1997 StandoutNature
Inhibition of death receptor signals by cellular FLIP
1997 StandoutNature
Antimicrobial peptides of multicellular organisms
2002 StandoutNature
A homologue of the TNF receptor and its ligand enhance T-cell growth and dendritic-cell function
1997 StandoutNature
Phase I trial of thiotepa in combination with recombinant human granulocyte-macrophage colony-stimulating factor.
1992
Staphylococcus aureusInfections
1998 Standout
Identification and Characterization of ICH-2, a Novel Member of the Interleukin-1β-converting Enzyme Family of Cysteine Proteases
1995
Viral inhibition of inflammation: Cowpox virus encodes an inhibitor of the interleukin-1β converting enzyme
1992 Standout
Inflammasomes in health and disease
2012 StandoutNature
Decreased apoptosis in the brain and premature lethality in CPP32-deficient mice
1996 StandoutNature
Inhibition of the Caenorhabditis elegans cell-death protease CED-3 by a CED-3 cleavage site in baculovirus p35 protein
1995 StandoutNatureNobel
Cancer of the Ovary
2004 Standout
Defects in the Ubiquitin Pathway Induce Caspase-independent Apoptosis Blocked by Bcl-2
1998 StandoutNobel
Generation of large numbers of dendritic cells from mouse bone marrow cultures supplemented with granulocyte/macrophage colony-stimulating factor.
1992 StandoutNobel
Anthrax lethal toxin-induced inflammasome formation and caspase-1 activation are late events dependent on ion fluxes and the proteasome
2007
Altered Cytokine Export and Apoptosis in Mice Deficient in Interleukin-1β Converting Enzyme
1995 Science
Purified colony stimulating factors (G‐CSF and GM‐CSF) induce differentiation in human HL60 leukemic cells with suppression of clonogenicity
1987
A Short Polypeptide Marker Sequence Useful for Recombinant Protein Identification and Purification
1988
Expression of murine interleukin 7 in a murine glioma cell line results in reduced tumorigenicity in vivo.
1992 StandoutNobel
Proliferating dendritic cell progenitors in human blood.
1994 StandoutNobel
Apoptosis in the Pathogenesis and Treatment of Disease
1995 StandoutScience
Substrate specificity of the protease that processes human interleukin-1 beta.
1990
Loss of the autophagy protein Atg16L1 enhances endotoxin-induced IL-1β production
2008 StandoutNature
Human interleukin 7: molecular cloning and growth factor activity on human and murine B-lineage cells.
1989
A Maelll polymorphism near the dystrophin gene promoter by restriction of amplified DNA
1990 StandoutNobel
Characterization of the cell surface receptor for granulocyte-macrophage colony-stimulating factor.
1986
Purification and Characterization of Human Recombinant Precursor Interleukin 1 β
1989
THE ATP SYNTHASE—A SPLENDID MOLECULAR MACHINE
1997 StandoutNobel
Salmonella Exploits Caspase-1 to Colonize Peyer's Patches in a Murine Typhoid Model
2000
B cell precursor growth-promoting activity. Purification and characterization of a growth factor active on lymphocyte precursors.
1988
Identification of a monocyte specific pre-interleukin 1 beta convertase activity.
1989
Molecular Cloning of the Interleukin-1β Converting Enzyme
1992 Science
Marrow Stromal Cells as Stem Cells for Nonhematopoietic Tissues
1997 StandoutScience
Rapid and specific conversion of precursor interleukin 1 beta (IL-1 beta) to an active IL-1 species by human mast cell chymase.
1991
Potassium-inhibited processing of IL-1 beta in human monocytes.
1995
The Serpin Proteinase Inhibitor 9 Is an Endogenous Inhibitor of Interleukin 1β–Converting Enzyme (Caspase-1) Activity in Human Vascular Smooth Muscle Cells
2000
Purification and characterization of active human interleukin-1 beta-converting enzyme from THP.1 monocytic cells.
1993
A controlled trial of recombinant human granulocyte-macrophage colony- stimulating factor after total body irradiation, high-dose chemotherapy, and autologous bone marrow transplantation for acute lymphoblastic leukemia or malignant lymphoma
1992
Recombinant granulocyte/macrophage colony-stimulating factor activates macrophages to inhibit Trypanosoma cruzi and release hydrogen peroxide. Comparison with interferon gamma.
1987
Cloning of a T Cell Growth Factor that Interacts with the β Chain of the Interleukin-2 Receptor
1994 StandoutScience
Unconventional Secretion, Unconventional Solutions
2013 StandoutScienceNobel
A bacterial invasin induces macrophage apoptosis by binding directly to ICE.
1996
Multiple Defects of Immune Cell Function in Mice with Disrupted Interferon-γ Genes
1993 StandoutScience
Interleukin-1 and interleukin-1 antagonism
1991 Standout
Molecular cloning and structure of the human interleukin-5 gene.
1987 StandoutNobel
Caspases: Enemies Within
1998 StandoutScience
Interleukin-1 beta converting enzyme requires oligomerization for activity of processed forms in vivo.
1995
Processing of precursor interleukin 1 beta and inflammatory disease.
1990
Mechanisms and Genes of Cellular Suicide
1995 StandoutScience
JNK1 controls mast cell degranulation and IL-1β production in inflammatory arthritis
2010 StandoutNobel
Genomic cloning, characterization, and multilineage growth-promoting activity of human granulocyte-macrophage colony-stimulating factor.
1986
Works of M. A. Cantrell being referenced
Generation of biologically active interleukin-1 beta by proteolytic cleavage of the inactive precursor.
1988
Cloning, sequence, and expression of a human granulocyte/macrophage colony-stimulating factor.
1985
Cloning, sequence, and expression of bovine interleukin 2.
1986