Standout Papers
Citation Impact
Citing Papers
Genetic Basis of Mitochondrial Function and Morphology in Saccharomyces cerevisiae
2002
Localization and activity of the SNARE Ykt6 determined by its regulatory domain and palmitoylation
2004 StandoutNobel
ER Tubules Mark Sites of Mitochondrial Division
2011 StandoutScience
Apg13p and Vac8p Are Part of a Complex of Phosphoproteins That Are Required for Cytoplasm to Vacuole Targeting
2000 StandoutNobel
Thematic review series: Lipid Posttranslational Modifications. Protein palmitoylation by a family of DHHC protein S-acyltransferases
2006
Computationally designed sensors detect endogenous Ras activity and signaling effectors at subcellular resolution
2024 StandoutNobel
Src-mediated Tyrosine Phosphorylation of Dynamin Is Required for β2-Adrenergic Receptor Internalization and Mitogen-activated Protein Kinase Signaling
1999 StandoutNobel
Erf4p and Erf2p Form an Endoplasmic Reticulum-associated Complex Involved in the Plasma Membrane Localization of Yeast Ras Proteins
2002
Differential Membrane Localization of ERas and Rheb, Two Ras-related Proteins Involved in the Phosphatidylinositol 3-Kinase/mTOR Pathway
2005 StandoutNobel
Bioorthogonal Chemistry: Fishing for Selectivity in a Sea of Functionality
2009 StandoutNobel
Enhancing extracellular vesicle cargo loading and functional delivery by engineering protein-lipid interactions
2024 StandoutNobel
Imaging beyond the proteome
2012 StandoutNobel
Mitochondria-targeted green fluorescent proteins: convenient tools for the study of organelle biogenesis inSaccharomyces cerevisiae
2000
Mitochondria: Dynamic Organelles in Disease, Aging, and Development
2006 Standout
Ras signaling on the Golgi
2006
Yeast mitochondrial dynamics: Fusion, division, segregation, and shape
2000
DHHC palmitoyl transferases: substrate interactions and (patho)physiology
2011
β-Propeller Blades as Ancestral Peptides in Protein Evolution
2013
Fzo1p Is a Mitochondrial Outer Membrane Protein Essential for the Biogenesis of Functional Mitochondria in Saccharomyces cerevisiae
1998
Palmitoylation: policing protein stability and traffic
2006
Endoplasmic reticulum BIK initiates DRP1‐regulated remodelling of mitochondrial cristae during apoptosis
2005
Mitochondrial fusion and fission in cell life and death
2010 Standout
Regulated portals of entry into the cell
2003 StandoutNature
DNA topoisomerase II, genotoxicity, and cancer
2007
Mitochondria: In Sickness and in Health
2012 Standout
Mammalian display screening of diverse cystine-dense peptides for difficult to drug targets
2017 StandoutNobel
Mitochondria-Anchored Receptor Atg32 Mediates Degradation of Mitochondria via Selective Autophagy
2009 StandoutNobel
Mitochondrial Dynamics in Mammalian Health and Disease
2009
Reactive oxygen species (ROS) as pleiotropic physiological signalling agents
2020 Standout
2-Bromopalmitate and 2-(2-hydroxy-5-nitro-benzylidene)-benzo[b]thiophen-3-one inhibit DHHC-mediated palmitoylation in vitro
2008
Lipid-Anchored SNAREs Lacking Transmembrane Regions Fully Support Membrane Fusion during Neurotransmitter Release
2013 StandoutNobel
The Palmitoylation Machinery Is a Spatially Organizing System for Peripheral Membrane Proteins
2010
Mitochondrial dynamics and apoptosis
2008
Essential Role for G Protein-coupled Receptor Endocytosis in the Activation of Mitogen-activated Protein Kinase
1998 StandoutNobel
SNAREs — engines for membrane fusion
2006 Standout
Membrane Fusion
2003 StandoutNobel
Autophagy proteins regulate innate immune responses by inhibiting the release of mitochondrial DNA mediated by the NALP3 inflammasome
2010 Standout
Dynamin, endocytosis and intracellular signalling (Review)
1996
OPA1 (Kjer Type) Dominant Optic Atrophy: A Novel Mitochondrial Disease
2002
Processing of Mgm1 by the Rhomboid-type Protease Pcp1 Is Required for Maintenance of Mitochondrial Morphology and of Mitochondrial DNA
2003
Mitochondrial dynamics and division in budding yeast
2002
Regulating the regulator: post-translational modification of RAS
2011
Photoconversion of matrix targeted GFP enables analysis of continuity and intermixing of the mitochondrial lumen
2003 StandoutNobel
Mitochondrial Membrane Permeabilization in Cell Death
2007 Standout
Human Topoisomerase IIα Rapidly Relaxes Positively Supercoiled DNA
2005
CH Bond Arylation in the Synthesis of Aryltetralin Lignans: A Short Total Synthesis of Podophyllotoxin
2014
Pharmacological Inhibition of Protein Lipidation
2015
Cellular palmitoylation and trafficking of lipidated peptides
2007
Drugging the undruggable RAS: Mission Possible?
2014
Purification and characterization of recombinant protein acyltransferases
2006
OPA1, encoding a dynamin-related GTPase, is mutated in autosomal dominant optic atrophy linked to chromosome 3q28
2000
Fission and selective fusion govern mitochondrial segregation and elimination by autophagy
2008 Standout
Src-dependent Tyrosine Phosphorylation Regulates Dynamin Self-assembly and Ligand-induced Endocytosis of the Epidermal Growth Factor Receptor
2002 StandoutNobel
Function, Attachment and Synthesis of Lipoic Acid in Escherichia coli
2005
Yeast and mammalian autophagosomes exhibit distinct phosphatidylinositol 3-phosphate asymmetries
2014 StandoutNobel
Mitochondria and cell death: outer membrane permeabilization and beyond
2010 Standout
Cooperative 4Pi Excitation and Detection Yields Sevenfold Sharper Optical Sections in Live-Cell Microscopy
2004 StandoutNobel
Identification of a Ras Palmitoyltransferase inSaccharomyces cerevisiae
2002
Merging mitochondria matters
2002
Gag3p, an Outer Membrane Protein Required for Fission of Mitochondrial Tubules
2000
Pfam: The protein families database in 2021
2020 Standout
The Novel F-Box Protein Mfb1p Regulates Mitochondrial Connectivity and Exhibits Asymmetric Localization in Yeast
2006
Dynamin and Its Role in Membrane Fission
2000
Small GTP-Binding Proteins
2001 Standout
Mitochondrial Morphology and Dynamics in Yeast and Multicellular Eukaryotes
2005
New Mechanistic and Functional Insights into DNA Topoisomerases
2013
Discovery and characterization of inhibitors of human palmitoyl acyltransferases
2006
Palmitoylation of oncogenic NRAS is essential for leukemogenesis
2010
Mammalian SWI/SNF chromatin remodeling complexes and cancer: Mechanistic insights gained from human genomics
2015
Recent advances in understanding structure–function relationships in the type II topoisomerase mechanism
2005
The Mitochondrial Protein hFis1 Regulates Mitochondrial Fission in Mammalian Cells through an Interaction with the Dynamin-Like Protein DLP1
2003
DNA Topoisomerase I Inhibitors: Chemistry, Biology, and Interfacial Inhibition
2009 Standout
Inactivation of the PBRM1 tumor suppressor gene amplifies the HIF-response in VHL −/− clear cell renal carcinoma
2017 StandoutNobel
Model organisms lead the way to protein palmitoyltransferases
2004
Lysosomal activity regulatesCaenorhabditis elegansmitochondrial dynamics through vitamin B12 metabolism
2020 StandoutNobel
Palmitoylation of Ligands, Receptors, and Intracellular Signaling Molecules
2006
Exploring Protein Lipidation with Chemical Biology
2011
Alternative topogenesis of Mgm1 and mitochondrial morphology depend on ATP and a functional import motor
2004
The Dynamin-Related Gtpase, Mgm1p, Is an Intermembrane Space Protein Required for Maintenance of Fusion Competent Mitochondria
2000
The genome-wide expression response to telomerase deletion in Saccharomyces cerevisiae
2002 StandoutNobel
Mitochondrial Fusion in Yeast Requires the Transmembrane GTPase Fzo1p
1998
Mitochondrial Fission, Fusion, and Stress
2012 StandoutScience
Chromone: A Valid Scaffold in Medicinal Chemistry
2014 Standout
Fluorophore Targeting to Cellular Proteins via Enzyme-Mediated Azide Ligation and Strain-Promoted Cycloaddition
2012 StandoutNobel
Palladium-Catalyzed Transformations of Alkyl C–H Bonds
2016 Standout
Click-Chemistry Based High Throughput Screening Platform for Modulators of Ras Palmitoylation
2017 StandoutNobel
The Dynamin-related GTPase, Dnm1p, Controls Mitochondrial Morphology in Yeast
1998
Identification of palmitoylated mitochondrial proteins using a bio‐orthogonal azido‐palmitate analogue
2007 StandoutNobel
Fast 100-nm resolution three-dimensional microscope reveals structural plasticity of mitochondria in live yeast
2002 StandoutNobel
UGO1 Encodes an Outer Membrane Protein Required for Mitochondrial Fusion
2001
Artificial Molecular Machines
2015 Standout
Drugging Topoisomerases: Lessons and Challenges
2012
H-ras but Not K-ras Traffics to the Plasma Membrane through the Exocytic Pathway
2000
Protein Lipidation: Occurrence, Mechanisms, Biological Functions, and Enabling Technologies
2018
MITOCHONDRIAL DYNAMICS IN YEAST
1998
Recent advances in understanding structure–function relationships in the type II topoisomerase mechanism
2005
Microtubules mediate mitochondrial distribution in fission yeast.
1996 StandoutNobel
The intracellular dynamic of protein palmitoylation
2010
Functional Interplay between Cristae Biogenesis, Mitochondrial Dynamics and Mitochondrial DNA Integrity
2019
Doxorubicin, DNA torsion, and chromatin dynamics
2013
Vac8p, a Vacuolar Protein with Armadillo Repeats, Functions in both Vacuole Inheritance and Protein Targeting from the Cytoplasm to Vacuole
1998
K-Ras4A splice variant is widely expressed in cancer and uses a hybrid membrane-targeting motif
2015
Early Detection of Anthracycline Cardiotoxicity and Improvement With Heart Failure Therapy
2015 Standout
Mitochondrial transmission during mating in Saccharomyces cerevisiae is determined by mitochondrial fusion and fission and the intramitochondrial segregation of mitochondrial DNA.
1997
The Machinery of Mitochondrial Inheritance and Behavior
1999 Science
Rapid detection, discovery, and identification of post‐translationally myristoylated proteins during apoptosis using a bio‐orthogonal azidomyristate analog
2007 StandoutNobel
Spatial and temporal dynamics of budding yeast mitochondria lacking the division component Fis1p
2003 StandoutNobel
Targeting RAS Membrane Association: Back to the Future for Anti-RAS Drug Discovery?
2015
Dnm1p Gtpase-Mediated Mitochondrial Fission Is a Multi-Step Process Requiring the Novel Integral Membrane Component Fis1p
2000
Vac7p, a Novel Vacuolar Protein, Is Required for Normal Vacuole Inheritance and Morphology
1997
Autophagy as a Regulated Pathway of Cellular Degradation
2000 StandoutScience
Mdv1p Is a Wd Repeat Protein That Interacts with the Dynamin-Related Gtpase, Dnm1p, to Trigger Mitochondrial Division
2000
Mitofusins Mfn1 and Mfn2 coordinately regulate mitochondrial fusion and are essential for embryonic development
2003 Standout
Regulation of mitochondrial morphology and inheritance by Mdm10p, a protein of the mitochondrial outer membrane.
1994
Works of Lynn Farh being referenced
Structure-Function Studies of Escherichia coli Biotin Synthase via a Chemical Modification and Site-Directed Mutagenesis Approach
2001
DHHC9 and GCP16 Constitute a Human Protein Fatty Acyltransferase with Specificity for H- and N-Ras
2005
Structure of the Topoisomerase IV C-terminal Domain
2004
Normal mitochondrial structure and genome maintenance in yeast requires the dynamin-like product of the MGM1 gene
1993
Structural Basis of Type II Topoisomerase Inhibition by the Anticancer Drug Etoposide
2011 StandoutScience
A polybasic domain allows nonprenylated Ras proteins to function in Saccharomyces cerevisiae.
1994