Citation Impact
Citing Papers
Cells resistant to HTI-286 do not overexpress P-glycoprotein but have reduced drug accumulation and a point mutation in alpha-tubulin.
2004
Probing the Probes: Fitness Factors For Small Molecule Tools
2010
Tubulin inhibitors. Synthesis and biological activity of HTI-286 analogs with B-segment heterosubstituents
2004
Enantioselective Total Synthesis of (+)‐Milnamide A and Evidence of Its Autoxidation to (+)‐Milnamide D
2004
The evolving role of natural products in drug discovery
2005 Standout
Photochemical Reactions as Key Steps in Natural Product Synthesis
2011
D-piece modifications of the hemiasterlin analog HTI-286 produce potent tubulin inhibitors
2004
Natural products: A continuing source of novel drug leads
2013 Standout
Natural products: An evolving role in future drug discovery
2011 Standout
Marine natural products
1990 Standout
Protein kinase inhibition of clinically important staurosporine analogues
2010
Life in cellulose houses: symbiotic bacterial biosynthesis of ascidian drugs and drug leads
2010
Drug development from marine natural products
2008 Standout
Heterocyclic scaffolds as promising anticancer agents against tumours of the central nervous system: Exploring the scope of indole and carbazole derivatives
2014
Marine natural products
2009
Marine pharmacology in 2003–2004: Anti-tumour and cytotoxic compounds
2006
Simple indole alkaloids and those with a non-rearranged monoterpenoid unit
2005
Stereoselective syntheses of α,β-unsaturated γ-amino esters through phosphine-catalyzed γ-umpolung additions of sulfonamides to γ-substituted allenoates
2015
Simple indole alkaloids and those with a nonrearranged monoterpenoid unit
2010 Standout
Natural products to drugs: natural product-derived compounds in clinical trials
2008 Standout
Catalytic Functionalization of Indoles in a New Dimension
2009 Standout
Synthesis and structure–activity relationships of N-6 substituted analogues of 9-hydroxy-4-phenylpyrrolo[3,4-c]carbazole-1,3(2H,6H)-diones as inhibitors of Wee1 and Chk1 checkpoint kinases
2007
Bis-imide granulatimide analogues as potent Checkpoint 1 kinase inhibitors
2006
Microtubule-binding agents: a dynamic field of cancer therapeutics
2010 Standout
Microtubules as a target for anticancer drugs
2004 Standout
Targeting DNA topoisomerase II in cancer chemotherapy
2009 Standout
The Cross‐Dehydrogenative Coupling of CH Bonds: A Versatile Strategy for CC Bond Formations
2013 Standout
Skepinone-L, a Novel Potent and Highly Selective Inhibitor of p38 MAP Kinase, Effectively Impairs Platelet Activation and Thrombus Formation
2013 Standout
Solid‐Phase Synthesis of Tetrahydro‐β‐carbolines and Tetrahydroisoquinolines by Stereoselective Intramolecular N‐Carbamyliminium Pictet–Spengler Reactions
2006 StandoutNobel
Targeting prostate cancer with HTI‐286, a synthetic analog of the marine sponge product hemiasterlin
2008
Synthesis and activity of novel analogs of hemiasterlin as inhibitors of tubulin polymerization: modification of the A segment
2004
Iron Catalysis in Organic Synthesis
2015 Standout
Marine Natural Products and Related Compounds in Clinical and Advanced Preclinical Trials
2004
Drug Discovery and Natural Products: End of an Era or an Endless Frontier?
2009 StandoutScience
Antitubulin agents for the treatment of cancer – a medicinal chemistry update
2006
Natural Product Synthesis Using Multicomponent Reaction Strategies
2009 Standout
HTI-286, a synthetic analogue of the tripeptide hemiasterlin, is a potent antimicrotubule agent that circumvents P-glycoprotein-mediated resistance in vitro and in vivo.
2003
Synthesis of Granulatimide Positional Analogues.
2003
Cells resistant to HTI-286 do not overexpress P-glycoprotein but have reduced drug accumulation and a point mutation in α-tubulin
2004
Synthesis, in vitro antiproliferative activities, and Chk1 inhibitory properties of dipyrrolo[3,4-a:3,4-c]carbazole-triones
2006
Two Photoaffinity Analogues of the Tripeptide, Hemiasterlin, Exclusively Label α-Tubulin
2005
A Synthesis of (±)‐Aplydactone
2016
Marine natural products
2015 Standout
Synthesis of isogranulatimides A and B analogues possessing a 7-azaindole unit instead of an indole moiety
2003
Synthesis of aminopyrimidylindoles structurally related to meridianins
2007
Practical Methodologies for the Synthesis of Indoles
2006 Standout
Synthesis and Functionalization of Indoles Through Palladium-catalyzed Reactions
2005 Standout
Phosphine Organocatalysis
2018 Standout
Sponge-Associated Microorganisms: Evolution, Ecology, and Biotechnological Potential
2007 Standout
Synthesis of Rebeccamycin and 11-Dechlororebeccamycin
1999
Utilizing the Power of Microbial Genetics to Bridge the Gap Between the Promise and the Application of Marine Natural Products
2005
Occurrence, Biogenesis, and Synthesis of Biologically Active Carbazole Alkaloids
2012 Standout
A Journey Under the Sea: The Quest for Marine Anti-Cancer Alkaloids
2011
Corrigendum to “Lamellarins and Related Pyrrole-Derived Alkaloids from Marine Organisms”: [Chemical Review 108 (2008) 264−287]
2009
Synthesis of N-alkyl substituted bioactive indolocarbazoles related to Gö6976
2006
Marine natural products
2017
Tumor Cells Resistant to a Microtubule-Depolymerizing Hemiasterlin Analogue, HTI-286, Have Mutations in α- or β-Tubulin and Increased Microtubule Stability
2004
Diastereoselective Allylation of Carbonyl Compounds and Imines: Application to the Synthesis of Natural Products
2013 Standout
Improved Synthesis of Isogranulatimide, a G2 Checkpoint Inhibitor. Syntheses of Didemnimide C, Isodidemnimide A, Neodidemnimide A, 17-Methylgranulatimide, and Isogranulatimides A−C
1999
Heterocyclic Anticancer Compounds: Recent Advances and the Paradigm Shift towards the Use of Nanomedicine’s Tool Box
2015 Standout
Marine natural products
2018 Standout
New Synthetic Route to Granulatimide and Its Structural Analogues.
2002
Synthesis of two series of pyrazolic analogues of the marine alkaloids granulatimide and isogranulatimide as potent Checkpoint 1 kinase inhibitors
2010
Dual Catalysis Strategies in Photochemical Synthesis
2016 Standout
Impact of Natural Products on Developing New Anti-Cancer Agents
2009 Standout
Transition Metal Complexes in Organic Synthesis, Part 73. Synthetic Routes to Naturally Occurring Furocarbazoles
2004
Synthesis of granulatimide bis-imide analogues
2005
Applications of Palladium-Catalyzed C–N Cross-Coupling Reactions
2016 Standout
Alkaloids from Marine Ascidians
2011
Photoredox Catalysis in Organic Chemistry
2016 Standout
Kinase Inhibitors of Marine Origin
2013
Visible‐Light Photocatalysis: Does It Make a Difference in Organic Synthesis?
2018 Standout
An Essential Role for MCL-1 in ATR-mediated CHK1 Phosphorylation
2008
Synthesis of granulatimide analogues bearing a maleimide instead of an imidazole heterocycle
2003
Spirastrellolide A, An Antimitotic Macrolide Isolated from the Caribbean Marine Sponge Spirastrella coccinea
2003
The merger of transition metal and photocatalysis
2017 Standout
Molecular orbital calculations, experimental and theoretical UV spectra of granulatimides and didemnimides, biologically active polycyclic heteroaromatic alkaloids from the ascidian Didemnum granulatum
2001
Synthesis of isogranulatimide analogues possessing a pyrrole moiety instead of an imidazole heterocycle
2003
Solar Synthesis: Prospects in Visible Light Photocatalysis
2014 StandoutScience
First synthesis of symmetrical and non-symmetrical aza indolocarbazoles derivatives
2002
The Essential Medicinal Chemistry of Curcumin
2017 Standout
Lamellarins and Related Pyrrole-Derived Alkaloids from Marine Organisms
2007 Standout
Synthesis and biological activity of pyrrole, pyrroline and pyrrolidine derivatives with two aryl groups on adjacent positions
2006 Standout
Pyrrole: a resourceful small molecule in key medicinal hetero-aromatics
2015 Standout
Pyrrole Synthesis via Allylic sp3 C−H Activation of Enamines Followed by Intermolecular Coupling with Unactivated Alkynes
2010 Standout
Isolation and Synthesis of Biologically Active Carbazole Alkaloids
2002 Standout
Enantioselective Total Synthesis of (+)‐Milnamide A and Evidence of Its Autoxidation to (+)‐Milnamide D
2004
Synthesis of polysubstituted pyrroles via Ag(I)-mediated conjugate addition and cyclization reaction of terminal alkynes with amines
2013
Works of Lynette Lim being referenced
Granulatimide and Isogranulatimide, Aromatic Alkaloids with G2 Checkpoint Inhibition Activity Isolated from the Brazilian Ascidian Didemnum granulatum: Structure Elucidation and Synthesis
1998
Synthesis and Antimitotic/Cytotoxic Activity of Hemiasterlin Analogues
2002
Inhibition of Chk1 by the G2 DNA damage checkpoint inhibitor isogranulatimide
2004