Citation Impact
Citing Papers
Selective targeting of engineered T cells using orthogonal IL-2 cytokine-receptor complexes
2018 StandoutScienceNobel
CTLA-4 Control over Foxp3 + Regulatory T Cell Function
2008 StandoutScienceNobel
CCR7 provides localized access to IL-2 and defines homeostatically distinct regulatory T cell subsets
2013
Blockade of CTLA-4 on both effector and regulatory T cell compartments contributes to the antitumor activity of anti–CTLA-4 antibodies
2009 StandoutNobel
Fc-dependent depletion of tumor-infiltrating regulatory T cells co-defines the efficacy of anti–CTLA-4 therapy against melanoma
2013 StandoutNobel
Macrophage PI3Kγ Drives Pancreatic Ductal Adenocarcinoma Progression
2016
A sex-biased imbalance between Tfr, Tph, and atypical B cells determines antibody responses in COVID-19 patients
2023 StandoutNobel
Construction of self-recognizing regulatory T cells from conventional T cells by controlling CTLA-4 and IL-2 expression
2013 StandoutNobel
Systemic CTLA-4 Blockade Ameliorates Glioma-Induced Changes to the CD4+ T Cell Compartment without Affecting Regulatory T-Cell Function
2007 StandoutNobel
The microbiota regulates type 2 immunity through RORγt + T cells
2015 StandoutScienceNobel
PD-1 + regulatory T cells amplified by PD-1 blockade promote hyperprogression of cancer
2019 StandoutNobel
CTLA-4 up-regulation of lymphocyte function-associated antigen 1 adhesion and clustering as an alternate basis for coreceptor function
2005
The p110δ Isoform of Phosphoinositide 3-Kinase Controls Clonal Expansion and Differentiation of Th Cells
2006
CTLA-4 Controls Regulatory T Cell Peripheral Homeostasis and Is Required for Suppression of Pancreatic Islet Autoimmunity
2009
Platelet factor 4–induced T H 1-T reg polarization suppresses antitumor immunity
2024 StandoutScienceNobel
miR-142-5p and miR-130a-3p are regulated by IL-4 and IL-13 and control profibrogenic macrophage program
2015
Re-establishing immunological self-tolerance in autoimmune disease
2012 StandoutNobel
PD-1 modulates regulatory T-cell homeostasis during low-dose interleukin-2 therapy
2017
Cytokines in inflammatory bowel disease
2014 Standout
M1 and M2 Macrophages: Oracles of Health and Disease
2012
Type 2 cytokines: mechanisms and therapeutic strategies
2015
Tumor-associated macrophages in cancers
2015
Treg and CTLA-4: Two intertwining pathways to immune tolerance
2013
A Dietary Fiber-Deprived Gut Microbiota Degrades the Colonic Mucus Barrier and Enhances Pathogen Susceptibility
2016 Standout
The promise of low-dose interleukin-2 therapy for autoimmune and inflammatory diseases
2015
Amino acid auxotrophy as a system of immunological control nodes
2016
Functional polarization of tumour-associated macrophages by tumour-derived lactic acid
2014 StandoutNature
Bronchiolitis obliterans in lung transplantation: the good, the bad, and the future
2009
Self-antigen-Driven Activation Induces Instability of Regulatory T Cells during an Inflammatory Autoimmune Response
2013
Macrophages are critical to the maintenance of IL-13-dependent lung inflammation and fibrosis
2015
Hypoxia and the extracellular matrix: drivers of tumour metastasis
2014 StandoutNobel
Macrophages in Tissue Repair, Regeneration, and Fibrosis
2016 Standout
The emerging role of CTLA4 as a cell-extrinsic regulator of T cell responses
2011
The B7/CD28 costimulatory family in autoimmunity
2005
CTLA4 gene polymorphism and autoimmunity
2005
Metabolic Competition in the Tumor Microenvironment Is a Driver of Cancer Progression
2015 Standout
Primary, Adaptive, and Acquired Resistance to Cancer Immunotherapy
2017 Standout
CTLA-4 suppresses the pathogenicity of self antigen–specific T cells by cell-intrinsic and cell-extrinsic mechanisms
2009
Mechanisms of fibrosis: therapeutic translation for fibrotic disease
2012 Standout
Angiotensin inhibition enhances drug delivery and potentiates chemotherapy by decompressing tumour blood vessels
2013 StandoutNobel
The gastrointestinal mucus system in health and disease
2013
An essential role for the IL-2 receptor in Treg cell function
2016
IgG4-related disease
2014 Standout
Phenotypic and functional plasticity of cells of innate immunity: macrophages, mast cells and neutrophils
2011
Protective and pathogenic functions of macrophage subsets
2011 Standout
Adenovirus-mediated HIF-1α gene transfer promotes repair of mouse airway allograft microvasculature and attenuates chronic rejection
2011 StandoutNobel
Distinct Cellular Mechanisms Underlie Anti-CTLA-4 and Anti-PD-1 Checkpoint Blockade
2017 StandoutNobel
Mechanisms maintaining peripheral tolerance
2009
Macrophage biology in development, homeostasis and disease
2013 StandoutNature
The PI3K Pathway in Human Disease
2017 Standout
Nintedanib inhibits macrophage activation and ameliorates vascular and fibrotic manifestations in the Fra2 mouse model of systemic sclerosis
2017
Thrombospondin1 in tissue repair and fibrosis: TGF-β-dependent and independent mechanisms
2012
CD28 costimulation of developing thymocytes induces Foxp3 expression and regulatory T cell differentiation independently of interleukin 2
2005
Barrier Epithelial Cells and the Control of Type 2 Immunity
2015
Diversity in CD8+ T cell differentiation
2009
Host protective roles of type 2 immunity: Parasite killing and tissue repair, flip sides of the same coin
2014
Resistin-like molecule alpha1 (Fizz1) recruits lung dendritic cells without causing pulmonary fibrosis
2012
The role of interleukin-2 during homeostasis and activation of the immune system
2012
Enhanced selection of FoxP3 + T-regulatory cells protects CTLA-4-deficient mice from CNS autoimmune disease
2009
Helminth-induced arginase-1 exacerbates lung inflammation and disease severity in tuberculosis
2015
Host Responses in Tissue Repair and Fibrosis
2012
Myeloid-Specific Disruption of Tyrosine Phosphatase Shp2 Promotes Alternative Activation of Macrophages and Predisposes Mice to Pulmonary Fibrosis
2014
Detection of self-reactive CD8 + T cells with an anergic phenotype in healthy individuals
2014 StandoutScienceNobel
Macrophage Polarization
2016 Standout
Mechanisms of Organ Injury and Repair by Macrophages
2016
Nonoverlapping roles of PD-1 and FoxP3 in maintaining immune tolerance in a novel autoimmune pancreatitis mouse model
2016 StandoutNobel
Differential Ly-6C expression identifies the recruited macrophage phenotype, which orchestrates the regression of murine liver fibrosis
2012
IL-10+CTLA-4+ Th2 Inhibitory Cells Form in a Foxp3-Independent, IL-2–Dependent Manner from Th2 Effectors during Chronic Inflammation
2012
Blockade of CTLA-4 on CD4+CD25+ Regulatory T Cells Abrogates Their Function In Vivo
2006
Immunologic and clinical effects of antibody blockade of cytotoxic T lymphocyte-associated antigen 4 in previously vaccinated cancer patients
2008 StandoutNobel
Macrophage PTEN Regulates Expression and Secretion of Arginase I Modulating Innate and Adaptive Immune Responses
2014
Induction of autoimmune disease by deletion of CTLA-4 in mice in adulthood
2016 StandoutNobel
Spermidine in health and disease
2018 StandoutScience
Foxp3+natural regulatory T cells preferentially form aggregates on dendritic cellsin vitroand actively inhibit their maturation
2008 StandoutNobel
IL-25 and type 2 innate lymphoid cells induce pulmonary fibrosis
2013
Nintedanib in Progressive Fibrosing Interstitial Lung Diseases
2019 Standout
Liver Fibrosis: Mechanistic Concepts and Therapeutic Perspectives
2020
IL-17A Enhances the Expression of Profibrotic Genes through Upregulation of the TGF-β Receptor on Hepatic Stellate Cells in a JNK-Dependent Manner
2014
Proenkephalin+regulatory T cells expanded by ultraviolet B exposure maintain skin homeostasis with a healing function
2020 StandoutNobel
Epigenetic conversion of conventional T cells into regulatory T cells by CD28 signal deprivation
2020 StandoutNobel
Adventitial Fibroblasts Induce a Distinct Proinflammatory/Profibrotic Macrophage Phenotype in Pulmonary Hypertension
2014
T cell exclusion, immune privilege, and the tumor microenvironment
2015 StandoutScience
Treg-expressed CTLA-4 depletes CD80/CD86 by trogocytosis, releasing free PD-L1 on antigen-presenting cells
2021 StandoutNobel
Single dose of anti–CTLA-4 enhances CD8 + T-cell memory formation, function, and maintenance
2010 StandoutNobel
Regulatory roles of IL-10–producing human follicular T cells
2019 StandoutNobel
Hypoxia-Inducible Factor 1α Is a Critical Downstream Mediator for Hypoxia-Induced Mitogenic Factor (FIZZ1/RELMα)–Induced Pulmonary Hypertension
2015 StandoutNobel
Inflammation and metabolism in tissue repair and regeneration
2017 StandoutScience
Tissue-specific expression of B7x protects from CD4 T cell–mediated autoimmunity
2011 StandoutNobel
Macrophage depletion reduces postsurgical tumor recurrence and metastatic growth in a spontaneous murine model of melanoma
2015
A distinct subpopulation of CD25−T-follicular regulatory cells localizes in the germinal centers
2017 StandoutNobel
Macrophage arginase-1 controls bacterial growth and pathology in hypoxic tuberculosis granulomas
2014
Fast detection of liver fibrosis with collagen-binding single-nanometer iron oxide nanoparticles via T 1 -weighted MRI
2023 StandoutNobel
Integrating mechanisms of pulmonary fibrosis
2011 Standout
Differential control of human Treg and effector T cells in tumor immunity by Fc-engineered anti–CTLA-4 antibody
2018 StandoutNobel
Works of Luke Barron being referenced
Muc5ac: a critical component mediating the rejection of enteric nematodes
2011
Cutting Edge: Contributions of Apoptosis and Anergy to Systemic T Cell Tolerance
2008
Distinct regions in the CD28 cytoplasmic domain are required for T helper type 2 differentiation
2004
Macrophages: Master Regulators of Inflammation and Fibrosis
2010 Standout
Macrophage activation governs schistosomiasis‐induced inflammation and fibrosis
2011
Interleukin‐2 in the development and control of inflammatory disease
2008
Role of Arginase 1 from Myeloid Cells in Th2-Dominated Lung Inflammation
2013
Incomplete Deletion of IL-4Rα by LysMCre Reveals Distinct Subsets of M2 Macrophages Controlling Inflammation and Fibrosis in Chronic Schistosomiasis
2014
Quantitative Assessment of Macrophage Functions in Repair and Fibrosis
2011
Cutting Edge: Mechanisms of IL-2–Dependent Maintenance of Functional Regulatory T Cells
2010
Cooperative Roles of CTLA-4 and Regulatory T Cells in Tolerance to an Islet Cell Antigen
2004
Melanoma-initiating cells exploit M2 macrophage TGFβ and arginase pathway for survival and proliferation
2014
Fibrosis is regulated by Th2 and Th17 responses and by dynamic interactions between fibroblasts and macrophages
2011
Combinatorial targeting of TSLP, IL-25, and IL-33 in type 2 cytokine–driven inflammation and fibrosis
2016