Citation Impact
Citing Papers
Selective targeting of engineered T cells using orthogonal IL-2 cytokine-receptor complexes
2018 StandoutScienceNobel
Generation of knock-in primary human T cells using Cas9 ribonucleoproteins
2015 StandoutNobel
Genome-wide CRISPR screens reveal a specific ligand for the glycan-binding immune checkpoint receptor Siglec-7
2021 StandoutNobel
Mouse models of acute and chronic hepacivirus infection
2017 StandoutScienceNobel
Preexisting Levels of CD4 T Cells Expressing PD-1 Are Related to Overall Survival in Prostate Cancer Patients Treated with Ipilimumab
2015
Exploiting the Mutanome for Tumor Vaccination
2012
PD-1 + regulatory T cells amplified by PD-1 blockade promote hyperprogression of cancer
2019 StandoutNobel
T cell costimulatory receptor CD28 is a primary target for PD-1–mediated inhibition
2017 Science
Multifactorial T-cell Hypofunction That Is Reversible Can Limit the Efficacy of Chimeric Antigen Receptor–Transduced Human T cells in Solid Tumors
2014
CRISPR/Cas9 mutagenesis invalidates a putative cancer dependency targeted in on-going clinical trials
2017
T-cell exhaustion in the tumor microenvironment
2015
MART-1 peptide vaccination plus IMP321 (LAG-3Ig fusion protein) in patients receiving autologous PBMCs after lymphodepletion: results of a Phase I trial
2014
PD-1 expression by tumour-associated macrophages inhibits phagocytosis and tumour immunity
2017 StandoutNature
Soft corrugated channel with synergistic exclusive discrimination gating for CO2 recognition in gas mixture
2023 StandoutNobel
T cell differentiation in chronic infection and cancer: functional adaptation or exhaustion?
2014
Determining cell type abundance and expression from bulk tissues with digital cytometry
2019 Standout
Elements of cancer immunity and the cancer–immune set point
2017 StandoutNature
Pembrolizumab versus docetaxel for previously treated, PD-L1-positive, advanced non-small-cell lung cancer (KEYNOTE-010): a randomised controlled trial
2015 Standout
A Distinct Gene Module for Dysfunction Uncoupled from Activation in Tumor-Infiltrating T Cells
2016
mRNA vaccines — a new era in vaccinology
2018 StandoutNobel
4-1BB costimulation ameliorates T cell exhaustion induced by tonic signaling of chimeric antigen receptors
2015
The biology and management of non-small cell lung cancer
2018 StandoutNature
High-throughput epitope discovery reveals frequent recognition of neo-antigens by CD4+ T cells in human melanoma
2014
Plasticity of tumour and immune cells: a source of heterogeneity and a cause for therapy resistance?
2013
Adoptive T Cell Transfer for Cancer Immunotherapy in the Era of Synthetic Biology
2013
The tumour microenvironment after radiotherapy: mechanisms of resistance and recurrence
2015 Standout
Influence of tumour micro-environment heterogeneity on therapeutic response
2013 StandoutNature
The Transcription Factor FoxO1 Sustains Expression of the Inhibitory Receptor PD-1 and Survival of Antiviral CD8+ T Cells during Chronic Infection
2014
Phosphoenolpyruvate Is a Metabolic Checkpoint of Anti-tumor T Cell Responses
2015
Inhibitory Receptors Beyond T Cell Exhaustion
2015
PD-1 and BTLA and CD8+T-cell “exhaustion” in cancer
2012
Interdependent IL-7 and IFN-γ signalling in T-cell controls tumour eradication by combined α-CTLA-4+α-PD-1 therapy
2016 StandoutNobel
Inhibitory Receptor Expression Depends More Dominantly on Differentiation and Activation than “Exhaustion” of Human CD8 T Cells
2013
Adoptive immunotherapy for cancer: harnessing the T cell response
2012
Prospective identification of neoantigen-specific lymphocytes in the peripheral blood of melanoma patients
2016
Molecular and Genetic Properties of Tumors Associated with Local Immune Cytolytic Activity
2015 Standout
Basic principles of tumor-associated regulatory T cell biology
2012
Immune Checkpoint Targeting in Cancer Therapy: Toward Combination Strategies with Curative Potential
2015 StandoutNobel
PD-1 and PD-L1 Immune Checkpoint Blockade to Treat Breast Cancer
2016 Standout
Novel cancer immunotherapy agents with survival benefit: recent successes and next steps
2011 StandoutNobel
Negative immune checkpoints on T lymphocytes and their relevance to cancer immunotherapy
2015
Overcoming T cell exhaustion in infection and cancer
2015
Frequencies of circulating MDSC correlate with clinical outcome of melanoma patients treated with ipilimumab
2013
The evolution of checkpoint blockade as a cancer therapy: what's here, what's next?
2015
Common pitfalls in preclinical cancer target validation
2017 StandoutNobel
Immune Memory and Exhaustion: Clinically Relevant Lessons from the LCMV Model
2015
Molecular mechanisms of T cell co-stimulation and co-inhibition
2013 Standout
Metabolic Competition in the Tumor Microenvironment Is a Driver of Cancer Progression
2015 Standout
Primary, Adaptive, and Acquired Resistance to Cancer Immunotherapy
2017 Standout
EMT: 2016
2016 Standout
The blockade of immune checkpoints in cancer immunotherapy
2012 Standout
Tumor-Specific T Cell Dysfunction Is a Dynamic Antigen-Driven Differentiation Program Initiated Early during Tumorigenesis
2016
Understanding the Intersections between Metabolism and Cancer Biology
2017 Standout
Coinhibitory Receptor Expression and Immune Checkpoint Blockade: Maintaining a Balance in CD8+ T Cell Responses to Chronic Viral Infections and Cancer
2017 StandoutNobel
Molecularly defined vaccines for cancer immunotherapy, and protective T cell immunity
2010
Molecular Recognition in Chemical and Biological Systems
2015
Network Analysis Reveals Centrally Connected Genes and Pathways Involved in CD8+ T Cell Exhaustion versus Memory
2012
Distinct Cellular Mechanisms Underlie Anti-CTLA-4 and Anti-PD-1 Checkpoint Blockade
2017 StandoutNobel
Chimeric Antigen Receptor T Cells for Sustained Remissions in Leukemia
2014 Standout
The PI3K Pathway in Human Disease
2017 Standout
Liver Environment and HCV Replication Affect Human T-Cell Phenotype and Expression of Inhibitory Receptors
2013
Anti-PD-1 and Anti-CTLA-4 Therapies in Cancer: Mechanisms of Action, Efficacy, and Limitations
2018
Elevated Expression of CD160 and 2B4 Defines a Cytolytic HIV-Specific CD8+T-Cell Population in Elite Controllers
2015
Immune Checkpoint Blockade: A Common Denominator Approach to Cancer Therapy
2015 Standout
Signatures of T cell dysfunction and exclusion predict cancer immunotherapy response
2018 Standout
Atezolizumab for First-Line Treatment of Metastatic Nonsquamous NSCLC
2018 Standout
Detection of self-reactive CD8 + T cells with an anergic phenotype in healthy individuals
2014 StandoutScienceNobel
Adoptive cell transfer as personalized immunotherapy for human cancer
2015 StandoutScience
VEGF-A modulates expression of inhibitory checkpoints on CD8+ T cells in tumors
2015
Nanotechnology for Multimodal Synergistic Cancer Therapy
2017 Standout
The Stoichiometric Production of IL-2 and IFN-γ mRNA Defines Memory T Cells That Can Self-Renew After Adoptive Transfer in Humans
2012
The epigenetic landscape of T cell exhaustion
2016 Science
Chemotherapy induces enrichment of CD47 + /CD73 + /PDL1 + immune evasive triple-negative breast cancer cells
2018 StandoutNobel
Unique potential of 4-1BB agonist antibody to promote durable regression of HPV + tumors when combined with an E6/E7 peptide vaccine
2015 StandoutNobel
The future of immune checkpoint therapy
2015 StandoutScienceNobel
Mutated PPP1R3B Is Recognized by T Cells Used To Treat a Melanoma Patient Who Experienced a Durable Complete Tumor Regression
2013
Going viral: chimeric antigen receptor T‐cell therapy for hematological malignancies
2014
Cancer Genome Landscapes
2013 StandoutScience
Precision glycocalyx editing as a strategy for cancer immunotherapy
2016 StandoutNobel
Modulation of Regulatory T Cell Function by Monocyte-Derived Dendritic Cells Matured through Electroporation with mRNA Encoding CD40 Ligand, Constitutively Active TLR4, and CD70
2013
Reactive Oxygen Species (ROS)-Based Nanomedicine
2019 Standout
Epigenetic conversion of conventional T cells into regulatory T cells by CD28 signal deprivation
2020 StandoutNobel
Clonal expansion of CD8 T cells in the systemic circulation precedes development of ipilimumab-induced toxicities
2016 StandoutNobel
T cell receptor binding affinity governs the functional profile of cancer-specific CD8+ T cells
2014
Neoantigens in cancer immunotherapy
2015 StandoutScience
Coincident signals from GPCRs and receptor tyrosine kinases are uniquely transduced by PI3Kβ in myeloid cells
2016
PD-1 identifies the patient-specific CD8+ tumor-reactive repertoire infiltrating human tumors
2014
CAR T cell immunotherapy for human cancer
2018 StandoutScience
Cancer immunotherapy using checkpoint blockade
2018 StandoutScience
Mitochondrial activation chemicals synergize with surface receptor PD-1 blockade for T cell-dependent antitumor activity
2017 StandoutNobel
De novo design of protein logic gates
2020 StandoutScienceNobel
N‐Carboxyanhydride Polymerization of Glycopolypeptides That Activate Antigen‐Presenting Cells through Dectin‐1 and Dectin‐2
2018 StandoutNobel
Works of Lukas Baitsch being referenced
Tumor Antigen–Specific FOXP3+ CD4 T Cells Identified in Human Metastatic Melanoma: Peptide Vaccination Results in Selective Expansion of Th1-like Counterparts
2009
Molecular profiling of CD 8 T cells in autochthonous melanoma identifies Maf as driver of exhaustion
2015
A PI3K p110β–Rac signalling loop mediates Pten-loss-induced perturbation of haematopoiesis and leukaemogenesis
2015
Extended Co-Expression of Inhibitory Receptors by Human CD8 T-Cells Depending on Differentiation, Antigen-Specificity and Anatomical Localization
2012
SHP-1 phosphatase activity counteracts increased T cell receptor affinity
2013
The three main stumbling blocks for anticancer T cells
2012
Vaccination‐induced functional competence of circulating human tumor‐specific CD8 T‐cells
2011
New organofluorine building blocks: inhibition of the malarial aspartic proteases plasmepsin II and IV by alicyclic α,α-difluoroketone hydrates
2009
Exhaustion of tumor-specific CD8+ T cells in metastases from melanoma patients
2011
MELK is an oncogenic kinase essential for mitotic progression in basal-like breast cancer cells
2014