Citation Impact
Citing Papers
Voltage sensor conformations in the open and closed states in rosetta structural models of K + channels
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A Modular PIP 2 Binding Site as a Determinant of Capsaicin Receptor Sensitivity
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Cytoplasmic ankyrin repeats of transient receptor potential A1 (TRPA1) dictate sensitivity to thermal and chemical stimuli
2011 StandoutNobel
Isothermal amplified detection of DNA and RNA
2014
Selective Gαi Subunits as Novel Direct Activators of Transient Receptor Potential Canonical (TRPC)4 and TRPC5 Channels
2012
The Nociceptor Ion Channel TRPA1 Is Potentiated and Inactivated by Permeating Calcium Ions
2008
ANKTM1, a TRP-like Channel Expressed in Nociceptive Neurons, Is Activated by Cold Temperatures
2003 StandoutNobel
Ionic currents underlying HTRP3 mediated agonist‐dependent Ca2+ influx in stably transfected HEK293 cells
1998
The developing relationship between receptor‐operated and store‐operated calcium channels in smooth muscle
2002
Activation of Store-Operated Ca2+ Current in Xenopus Oocytes Requires SNAP-25 but Not a Diffusible Messenger
1999 StandoutNobel
CD1d-dependent macrophage-mediated clearance of Pseudomonas aeruginosa from lung
2002
Structure of the TRPA1 ion channel suggests regulatory mechanisms
2015 StandoutNatureNobel
Requirement for the PDZ Domain Protein, INAD, for Localization of the TRP Store-Operated Channel to a Signaling Complex
1997
Exogenous and endogenous glycolipid antigens activate NKT cells during microbial infections
2005 StandoutNatureNobel
Role of the Inositol 1,4,5-Trisphosphate Receptor in Ca2+ Feedback Inhibition of Calcium Release-activated Calcium Current (I crac)
1999
Intracellular Ca2+ store-operated influx of Ca2+ through TRP-R, a rat homolog of TRP, expressed in Xenopus oocytes
1998
Cloning and Expression of a Novel Mammalian Homolog ofDrosophila Transient Receptor Potential (Trp) Involved in Calcium Entry Secondary to Activation of Receptors Coupled by the Gq Class of G Protein
1997
Regulation of Drosophila transient receptor potential‐like (TrpL) channels by phospholipase C‐dependent mechanisms
2001
Properties of heterologously expressed hTRP3 channels in bovine pulmonary artery endothelial cells
1999
Noxious compounds activate TRPA1 ion channels through covalent modification of cysteines
2007 StandoutNatureNobel
Molecular mechanisms of nociception
2001 StandoutNatureNobel
Does a decrease in subplasmalemmal Ca2+ explain how storemoperated Ca2+ channels are opened?
1998
From worm to man: three subfamilies of TRP channels
2000
The venerable inveterate invertebrate TRP channels
2003
A Capacitative Calcium Current in Cultured Skeletal Muscle Cells Is Mediated by the Calcium-specific Leak Channel and Inhibited by Dihydropyridine Compounds
1996
TRPC1 and TRPC5 Form a Novel Cation Channel in Mammalian Brain
2001
Role of Tumour Necrosis Factor-?? in the Progression of Heart Failure
2000
Multiple roles of calmodulin and other Ca2+-binding proteins in the functional regulation of TRP channels
2005
The capsaicin receptor: a heat-activated ion channel in the pain pathway
1997 StandoutNatureNobel
Homer Binds TRPC Family Channels and Is Required for Gating of TRPC1 by IP3 Receptors
2003
TRP, TRPL and trouble in photoreceptor cells
1998
Conductance and permeation of monovalent cations through depletion-activated Ca2+ channels (ICRAC) in Jurkat T cells
1996
TRP channels and lipids: from Drosophila to mammalian physiology
2006
InsP3 Receptor Is Essential for Growth and Differentiation but Not for Vision in Drosophila
1997
Lack of an endothelial store-operated Ca2+ current impairs agonist-dependent vasorelaxation in TRP4−/− mice
2001
Ca2+-mediated Potentiation of the Swelling-induced Taurine Efflux from HeLa Cells: On the Role of Calmodulin and Novel Protein Kinase C Isoforms
2004
Protein Kinase C Activates Store-operated Ca2+Channels in Human Glomerular Mesangial Cells
2001
A capsaicin-receptor homologue with a high threshold for noxious heat
1999 StandoutNatureNobel
Ion currents of Xenopus laevis oocytes: state of the art
1999
Vanilloid receptors on sensory nerves mediate the vasodilator action of anandamide
1999 StandoutNatureNobel
Irritant-evoked activation and calcium modulation of the TRPA1 receptor
2020 StandoutNatureNobel
Polyunsaturated fatty acids activate the Drosophila light-sensitive channels TRP and TRPL
1999 Nature
Structure of an HIV gp120 envelope glycoprotein in complex with the CD4 receptor and a neutralizing human antibody
1998 StandoutNature
Cloning and Functional Expression of Human Short TRP7, a Candidate Protein for Store-operated Ca2+ Influx
2002
Molecular cloning of a widely expressed human homologue for the Drosophila trp gene
1995
Cloning and Functional Expression of a Human Ca2+-Permeable Cation Channel Activated by Calcium Store Depletion
1996
A Bivalent Tarantula Toxin Activates the Capsaicin Receptor, TRPV1, by Targeting the Outer Pore Domain
2010 StandoutNobel
The N-Terminal Domain of the IP3 Receptor Gates Store-Operated hTrp3 Channels
1999
The Role of Endogenous Human Trp4 in Regulating Carbachol-induced Calcium Oscillations in HEK-293 Cells
2002
The Drosophila Light-Activated Conductance Is Composed of the Two Channels TRP and TRPL
1996
Store-Operated Calcium Channels
2005 Standout
In Vivo Analysis of the Drosophila Light-Sensitive Channels, TRP and TRPL
1997
The VGL-Chanome: A Protein Superfamily Specialized for Electrical Signaling and Ionic Homeostasis
2004
Calmodulin Regulates Ca2+-Dependent Feedback Inhibition of Store-Operated Ca2+ Influx by Interaction with a Site in the C Terminus of TrpC1
2002
Depletion of Intracellular Calcium Stores Activates a Calcium Conducting Nonselective Cation Current in Mouse Pancreatic Acinar Cells
1996
STIMulating store-operated Ca2+ entry
2009
TRP channels as cellular sensors
2003 StandoutNature
Comparison of Human TRPC3 Channels in Receptor-activated and Store-operated Modes
2002
Calcium and barium permeation through calcium release-activated calcium (CRAC) channels
1995
A Cell-Penetrating Scorpion Toxin Enables Mode-Specific Modulation of TRPA1 and Pain
2019 StandoutNobel
The Membrane Topology of Human Transient Receptor Potential 3 as Inferred from Glycosylation-scanning Mutagenesis and Epitope Immunocytochemistry
1998
The cellular and molecular basis of store-operated calcium entry
2002
Enterochromaffin Cells Are Gut Chemosensors that Couple to Sensory Neural Pathways
2017 StandoutNobel
Receptor-activated Ca2+ Influx via Human Trp3 Stably Expressed in Human Embryonic Kidney (HEK)293 Cells
1998
Activation of a TRPC3-Dependent Cation Current through the Neurotrophin BDNF
1999
A novel capacitative calcium entry channel expressed in excitable cells
1998
Bradykinin and nerve growth factor release the capsaicin receptor from PtdIns(4,5)P2-mediated inhibition
2001 StandoutNatureNobel
Tyrosine Sulfation of Human Antibodies Contributes to Recognition of the CCR5 Binding Region of HIV-1 gp120
2003
Structure of the TRPV1 ion channel determined by electron cryo-microscopy
2013 StandoutNatureNobel
Identification of a cold receptor reveals a general role for TRP channels in thermosensation
2002 StandoutNatureNobel
TRPV1 structures in nanodiscs reveal mechanisms of ligand and lipid action
2016 StandoutNatureNobel
Phenotype of a recombinant store‐operated channel: highly selective permeation of Ca2+
1999
A TRP Channel that Senses Cold Stimuli and Menthol
2002 StandoutNobel
Capacitative calcium entry is colocalised with calcium release in Xenopus oocytes: Evidence against a highly diffusible calcium influx factor
1996
Store Depletion-activated CaT1 Currents in Rat Basophilic Leukemia Mast Cells Are Inhibited by 2-Aminoethoxydiphenyl Borate
2002
Activation of heterologously expressed Drosophila TRPL channels: Ca2+ is not required and InsP3 is not sufficient
1998
TRP Is Cracked but Is CRAC TRP?
1996
trp, a Novel Mammalian Gene Family Essential for Agonist-Activated Capacitative Ca2+ Entry
1996
A novel mechanism for the store-operated calcium influx pathway
2004
Receptor-activated Ca2+ influx: how many mechanisms for how many channels?
1994
Capacitative calcium entry channels
1999
SWELL1, a Plasma Membrane Protein, Is an Essential Component of Volume-Regulated Anion Channel
2014 StandoutNobel
Molecular Basis for Species-Specific Sensitivity to “Hot” Chili Peppers
2002 StandoutNobel
Role of the Phospholipase C-Inositol 1,4,5-Trisphosphate Pathway in Calcium Release-activated Calcium Current and Capacitative Calcium Entry
2001
A unified nomenclature for short-chain peptides isolated from scorpion venoms: α-KTx molecular subfamilies
1999
12 Store-operated calcium channels
1999
TRPγ, a Drosophila TRP–Related Subunit, Forms a Regulated Cation Channel with TRPL
2000
Store depletion triggers the calcium release-activated calcium current ( I CRAC ) in macrovascular endothelial cells: a comparison with Jurkat and embryonic kidney cell lines
1998
Identification of Common Binding Sites for Calmodulin and Inositol 1,4,5-Trisphosphate Receptors on the Carboxyl Termini of Trp Channels
2001
Store-operated Ca2+ influx: What is the message from the stores to the membrane?
1996
Mustard oils and cannabinoids excite sensory nerve fibres through the TRP channel ANKTM1
2004 StandoutNatureNobel
The slicing activity of miRNA-specific Argonautes is essential for the miRNA pathway in C. elegans
2012
Systematic analysis of genes required for synapse structure and function
2005 StandoutNatureNobel
TRPA1 Mediates the Inflammatory Actions of Environmental Irritants and Proalgesic Agents
2006 StandoutNobel
Are Complex Behaviors Specified by Dedicated Regulatory Genes? Reasoning from Drosophila
2001 StandoutNobel
Transient receptor potential channels as molecular substrates of receptor-mediated cation entry
1999
Coassembly of TRP and TRPL Produces a Distinct Store-Operated Conductance
1997
Plasma Membrane Calcium Channels in Human Carcinoma A431 Cells Are Functionally Coupled to Inositol 1,4,5-Trisphosphate Receptor-Phosphatidylinositol 4,5-Bisphosphate Complexes
2000
Trp1, a Candidate Protein for the Store-operated Ca2+Influx Mechanism in Salivary Gland Cells
2000
Two distinct RNase activities of CRISPR-C2c2 enable guide-RNA processing and RNA detection
2016 StandoutNatureNobel
Calcium signaling
1995 Standout
TRP channels in Drosophila photoreceptor cells
2005
Small RNAs are modified with N-glycans and displayed on the surface of living cells
2021 StandoutNobel
Modeling neurodevelopmental disorder-associated humanAGO1mutations inCaenorhabditis elegansArgonautealg-1
2024 StandoutNobel
Molecular Cloning and Functional Characterization of a Novel Receptor-activated TRP Ca2+ Channel from Mouse Brain
1998
Caenorhabditis elegans ALG-1 antimorphic mutations uncover functions for Argonaute in microRNA guide strand selection and passenger strand disposal
2015 StandoutNobel
TRP Channel Proteins and Signal Transduction
2002
Acid potentiation of the capsaicin receptor determined by a key extracellular site
2000 StandoutNobel
Randomized, Double-Blind, Placebo-Controlled, Pilot Trial of Infliximab, a Chimeric Monoclonal Antibody to Tumor Necrosis Factor-α, in Patients With Moderate-to-Severe Heart Failure
2003 Standout
Rapid inactivation of depletion-activated calcium current (ICRAC) due to local calcium feedback.
1995
The Transient Receptor Potential Protein Homologue TRP6 Is the Essential Component of Vascular α1-Adrenoceptor–Activated Ca2+-Permeable Cation Channel
2001
Activation of vanilloid receptor type I in the endoplasmic reticulum fails to activate store-operated Ca2+ entry
2003
Essential control of an endothelial cell ISOC by the spectrin membrane skeleton
2001
MOD-1 is a serotonin-gated chloride channel that modulates locomotory behaviour in C. elegans
2000 StandoutNatureNobel
Differential expression of TNF-α, IL-6, and IGF-1 by graded mechanical stress in normal rat myocardium
2002
Ion Channels and Their Functional Role in Vascular Endothelium
2001
Activation of Trp3 by inositol 1,4,5-trisphosphate receptors through displacement of inhibitory calmodulin from a common binding domain
2001
Regulation of TRP Channels via Lipid Second Messengers
2003
The TRP Superfamily of Cation Channels
2005
TRPC1, a human homolog of a Drosophila store-operated channel.
1995
Receptor-activated Ca2+ inflow in animal cells: a variety of pathways tailored to meet different intracellular Ca2+ signalling requirements
1999
Capacitative Ca2+ Entry Is Closely Linked to the Filling State of Internal Ca2+ Stores: A Study Using Simultaneous Measurements of ICRAC and Intraluminal [Ca2+]
1998
Involvement of inducible nitric oxide synthase in cardiac dysfunction with tumor necrosis factor-α
2002
Cell surface receptors, virus entry and tropism of primate lentiviruses
2002
Molecular and Immune Mechanisms in the Pathogenesis of Cardiomyopathy
1997
Physiology, Phylogeny, and Functions of the TRP Superfamily of Cation Channels
2001
Dilated Cardiomyopathy in Transgenic Mice With Cardiac-Specific Overexpression of Tumor Necrosis Factor-α
1997
A sulfated metabolite produced bystf3negatively regulates the virulence ofMycobacteriumtuberculosis
2006 StandoutNobel
Polycystin-2, the protein mutated in autosomal dominant polycystic kidney disease (ADPKD), is a Ca 2+ -permeable nonselective cation channel
2000
Physiology, Phylogeny, and Functions of the TRP Superfamily of Cation Channels
2001
TRPM8 acute desensitization is mediated by calmodulin and requires PIP2: distinction from tachyphylaxis
2011
Two amino acid residues determine 2-APB sensitivity of the ion channels TRPV3 and TRPV4
2009 StandoutNobel
A mammalian capacitative calcium entry channel homologous to Drosophila TRP and TRPL.
1996
SIDT1 Localizes to Endolysosomes and Mediates Double-Stranded RNA Transport into the Cytoplasm
2019
On the molecular basis and regulation of cellular capacitative calcium entry: Roles for Trp proteins
1996
Human Trp3 forms both inositol trisphosphate receptor-dependent and receptor-independent store-operated cation channels in DT40 avian B lymphocytes
2001
Increased Nitric Oxide in Proportion to the Severity of Heart Failure in Patients With Dilated Cardiomyopathy. Close Correlation of Tumor Necrosis Factor-.ALPHA. With Systemic and Local Production of Nitric Oxide.
2002
Pathophysiologically Relevant Concentrations of Tumor Necrosis Factor-α Promote Progressive Left Ventricular Dysfunction and Remodeling in Rats
1998
A Conserved HIV gp120 Glycoprotein Structure Involved in Chemokine Receptor Binding
1998 Science
A store-operated nonselective cation channel in lymphocytes is activated directly by Ca2+ influx factor and diacylglycerol
2001
Putative capacitative calcium entry channels: expression of Drosophila trp and evidence for the existence of vertebrate homologues
1995
Altered sexual and social behaviors in trp2 mutant mice
2002 StandoutNobel
Alteration of Stimulus-Specific Guard Cell Calcium Oscillations and Stomatal Closing in Arabidopsis det3 Mutant
2000 StandoutScienceNobel
OSM-9, A Novel Protein with Structural Similarity to Channels, Is Required for Olfaction, Mechanosensation, and Olfactory Adaptation inCaenorhabditis elegans
1997
A Current Activated on Depletion of Intracellular Ca2+Stores Can Regulate Exocytosis in Adrenal Chromaffin Cells
1999
Structural insight into TRPV5 channel function and modulation
2019 StandoutNobel
Tyrosine Sulfation of the Amino Terminus of CCR5 Facilitates HIV-1 Entry
1999
Mechanism by which the lectin actinohivin blocks HIV infection of target cells
2009 StandoutNobel
Target-Cell Contact Activates a Highly Selective Capacitative Calcium Entry Pathway in Cytotoxic T Lymphocytes
2000
Metabolic Stress Reversibly Activates theDrosophilaLight-Sensitive Channels TRP and TRPLIn Vivo
2000
Visual Transduction in Drosophila
1999
Capacitative calcium entry in the nervous system
2003
Functional expression of TrpC1: a human homologue of the Drosophila Trp channel
1998
Cloning and expression of the human transient receptor potential 4 (TRP4) gene: localization and functional expression of human TRP4 and TRP3
2000
Modulation of Ca 2+ entry by polypeptides of the inositol 1,4,5-trisphosphate receptor (IP3R) that bind transient receptor potential (TRP): Evidence for roles of TRP and IP3R in store depletion-activated Ca 2+ entry
1999
Inhibition of endogenous TRP1 decreases capacitative Ca2+entry and attenuates pulmonary artery smooth muscle cell proliferation
2002
Activation of a Cl- current by hypotonic volume increase in human endothelial cells.
1994
Calcium-dependent potentiation of store-operated calcium channels in T lymphocytes.
1996
Characterization of T cell mutants with defects in capacitative calcium entry: genetic evidence for the physiological roles of CRAC channels.
1995
Autoimmune Dilated Cardiomyopathy in PD-1 Receptor-Deficient Mice
2001 StandoutScienceNobel
TRP Channels
2007 Standout
Scanning the human proteome for calmodulin-binding proteins
2005 StandoutNobel
Structural insights into TRPM8 inhibition and desensitization
2019 StandoutScienceNobel
Discovery of sulfated metabolites in mycobacteria with a genetic and mass spectrometric approach
2002 StandoutNobel
Host nutritional selenium status as a driving force for influenza virus mutations
2001
Expression of TRPC3 in Chinese Hamster Ovary Cells Results in Calcium-activated Cation Currents Not Related to Store Depletion
1997
Evidence that Ca2+-release-activated Ca2+ channels in rat hepatocytes are required for the maintenance of hormone-induced Ca2+ oscillations
2003
Expression and role of TRPC proteins in human platelets: evidence that TRPC6 forms the store-independent calcium entry channel
2002
Store-activated Ca2+ inflow in Xenopus laevis oocytes: inhibition by primaquine and evaluation of the role of membrane fusion
1996
Structural basis for gating charge movement in the voltage sensor of a sodium channel
2011 StandoutNobel
Works of Luis Vaca being referenced
STIM1 converts TRPC1 from a receptor-operated to a store-operated channel: Moving TRPC1 in and out of lipid rafts
2008
Calmodulin and Calcium Interplay in the Modulation of TRPC5 Channel Activity
2005
Characterization of the maitotoxin-induced calcium influx pathway from human skin fibroblasts
1997
Noxiustoxin 2, a novel K+ channel blocking peptide from the venom of the scorpion centruroides noxius Hoffmann
1996
A novel family of mammalian transmembrane proteins involved in cholesterol transport
2017
Osmotic Swelling‐Induced Changes in Cytosolic Calcium Do Not Affect Regulatory Volume Decrease in Rat Cultured Suspended Cerebellar Astrocytes
1998
Calmodulin inhibits calcium influx current in vascular endothelium
1996
The COOH-terminal Domain of Drosophila TRP Channels Confers Thapsigargin Sensitivity
1996
Mutations in the S4 domain of a pacemaker channel alter its voltage dependence
2000
Appearance of a Novel Ca2+ Influx Pathway in Sf9 Insect Cells Following Expression of the Transient Receptor Potential-like (trpl) Protein of Drosophila
1994
Calmodulin Modulates the Delay Period between Release of Calcium from Internal Stores and Activation of Calcium Influx via Endogenous TRP1 Channels
2002
G-protein-mediated regulation of a Ca2+-dependent K+ channel in cultured vascular endothelial cells
1992
Cellular basis for the negative inotropic effects of tumor necrosis factor-alpha in the adult mammalian heart.
1993
SITS Blockade Induces Multiple Subconductance States in a Large Conductance Chloride Channel
1999
Blockade of a KCa channel with synthetic peptides from noxiustoxin: A K+ channel blocker
1993
Ins(1,4,5)P3 activates Drosophila cation channel Trpl in recombinant baculovirus-infected Sf9 insect cells
1995
Molecular Beacons: Powerful Tools for Imaging RNA in Living Cells
2011
Properties of single Drosophila Trpl channels expressed in Sf9 insect cells
1997
A Tyrosine-Rich Region in the N Terminus of CCR5 Is Important for Human Immunodeficiency Virus Type 1 Entry and Mediates an Association between gp120 and CCR5
1998
Activation of recombinant trp by thapsigargin in Sf9 insect cells
1994
Modulation of a calcium-activated chloride current by Maitotoxin
1999
Depletion of intracellular Ca2+ stores activates a Ca(2+)-selective channel in vascular endothelium
1994
Modulation of cell membrane potential in cultured vascular endothelium
1996
cAMP-dependent phosphorylation modulates voltage gating in an endothelial Cl- channel
1993
Depletion and refilling of intracellular Ca2+ stores induce oscillations of Ca2+ current
1993
First step in pre-miRNAs processing by human Dicer
2009
IP3-activated Ca2+ channels in the plasma membrane of cultured vascular endothelial cells
1995