Citation Impact

Citing Papers

What is the total number of protein molecules per cell volume? A call to rethink some published values
2013
Bridging the gaps in design methodologies by evolutionary optimization of the stability and proficiency of designed Kemp eliminase KE59
2012 StandoutNobel
Dynamic profiling of the protein life cycle in response to pathogens
2015 Science
Thermodynamic prediction of protein neutrality
2005 StandoutNobel
Atomic-Level Characterization of the Structural Dynamics of Proteins
2010 StandoutScienceNobel
Directed evolution of a genetic circuit
2002 StandoutNobel
Dynamic equilibrium engagement of a polyvalent ligand with a single-site receptor
2008
Computational Thermostabilization of an Enzyme
2005 StandoutScienceNobel
Effects of Molecular Memory and Bursting on Fluctuations in Gene Expression
2008 Science
Protein stability promotes evolvability
2006 StandoutNobel
Cotranslational structure acquisition of nascent polypeptides monitored by NMR spectroscopy
2010
Attributes of short linear motifs
2011
An omics perspective of protein disorder
2011
Intense Neutral Drifts Yield Robust and Evolvable Consensus Proteins
2008
Computational Stabilization of a Non‐Heme Iron Enzyme Enables Efficient Evolution of New Function
2024 StandoutNobel
Proteome Dynamics: Revisiting Turnover with a Global Perspective
2012
Characterization of Functional Reprogramming during Osteoclast Development Using Quantitative Proteomics and mRNA Profiling
2014
Hallmarks of Cancer: The Next Generation
2011 Standout
Protein synthesis rate is the predominant regulator of protein expression during differentiation
2013
Mega-scale experimental analysis of protein folding stability in biology and design
2023 Nature
The role of disorder in interaction networks: a structural analysis
2008
The unfoldomics decade: an update on intrinsically disordered proteins
2008
Neutral genetic drift can alter promiscuous protein functions, potentially aiding functional evolution
2007 StandoutNobel
A “Proteomic Ruler” for Protein Copy Number and Concentration Estimation without Spike-in Standards
2014
Transcriptome and proteome quantification of a tumor model provides novel insights into post‐transcriptional gene regulation
2013
Local structural disorder imparts plasticity on linear motifs
2007
The Structure of the Transition State for Folding of Chymotrypsin Inhibitor 2 Analysed by Protein Engineering Methods: Evidence for a Nucleation-condensation Mechanism for Protein Folding
1995
Do viral proteins possess unique biophysical features?
2008
Folding dynamics and mechanism of β-hairpin formation
1997 Nature
A polymer physics perspective on driving forces and mechanisms for protein aggregation
2007
Mapping the structures of transition states and intermediates in folding: delineation of pathways at high resolution
1995
From molecular to modular cell biology
1999 StandoutNatureNobel
Matching theory and experiment in protein folding
1999 StandoutNobel
Casein kinase 2: An ‘eminence grise’ in cellular regulation?
1990
Fishing for folding nuclei in lattice models and proteins
1998
Is protein folding hierarchic? I. Local structure and peptide folding
1999
Computational studies of gene regulatory networks: in numero molecular biology
2001
Recognizing Native Folds by the Arrangement of Hydrophobic and Polar Residues
1995 StandoutNobel
Physicochemical Determinants of Chaperone Requirements
2010
A short linear peptide that folds into a native stable β-hairpin in aqueous solution
1994
Cell type– and brain region–resolved mouse brain proteome
2015
Experiment and theory highlight role of native state topology in SH3 folding.
1999 StandoutNobel
A Generic Program for Multistate Protein Design
2011
The Yin and Yang of protein folding
2005
3did: identification and classification of domain-based interactions of known three-dimensional structure
2010
The folding transition state between SH3 domains is conformationally restricted and evolutionarily conserved.
1999
Inference of Macromolecular Assemblies from Crystalline State
2007 Standout
Characterizing transition states in protein folding: an essential step in the puzzle
1995
Critical role of beta-hairpin formation in protein G folding.
2000 StandoutNobel
Contrasting roles for symmetrically disposed β-turns in the folding of a small protein
1997 StandoutNobel
Epithelial-Mesenchymal Transitions in Development and Disease
2009 Standout
From Levinthal to pathways to funnels
1997 Standout
Nature, Nurture, or Chance: Stochastic Gene Expression and Its Consequences
2008 Standout
Alternative mRNA transcription, processing, and translation: insights from RNA sequencing
2015
Directed enzyme evolution via small and effective neutral drift libraries
2008
Noise Propagation and Signaling Sensitivity in Biological Networks: A Role for Positive Feedback
2008
Conservation of rapid two-state folding in mesophilic, thermophilic and hyperthermophilic cold shock proteins
1998
The folding mechanism of a β-sheet: the WW domain
2001
The protein folding ‘speed limit’
2004
Design of protein-interaction specificity gives selective bZIP-binding peptides
2009 Nature
Φ-Analysis at the Experimental Limits: Mechanism of β-Hairpin Formation
2006
A breakdown of symmetry in the folding transition state of protein L
2000 StandoutNobel
Conformations of peptide fragments from the FK506 binding protein: comparison with the native and urea-unfolded states 1 1Edited by P. E. Wright
1999
Folding and stability of a tryptophan-containing mutant of ubiquitin
1993
Computationally designed libraries for rapid enzyme stabilization
2014 StandoutNobel
Natural Selection for Kinetic Stability Is a Likely Origin of Correlations between Mutational Effects on Protein Energetics and Frequencies of Amino Acid Occurrences in Sequence Alignments
2006
Global Subcellular Characterization of Protein Degradation Using Quantitative Proteomics
2012
Contextual Specificity in Peptide-Mediated Protein Interactions
2008
The dual role of a loop with low loop contact distance in folding and domain swapping
2002
Iterative Saturation Mutagenesis on the Basis of B Factors as a Strategy for Increasing Protein Thermostability
2006
DisProt: the Database of Disordered Proteins
2006
Robustness–epistasis link shapes the fitness landscape of a randomly drifting protein
2006 Nature
Roles of Phosphorylation and Helix Propensity in the Binding of the KIX Domain of CREB-binding Protein by Constitutive (c-Myb) and Inducible (CREB) Activators
2002
Computer design of obligate heterodimer meganucleases allows efficient cutting of custom DNA sequences
2008
Regulation of noise in the expression of a single gene
2002 Standout
The consensus concept for thermostability engineering of proteins
2000
Important role of hydrogen bonds in the structurally polarized transition state for folding of the src SH3 domain
1998 StandoutNobel
A Large Scale Test of Computational Protein Design: Folding and Stability of Nine Completely Redesigned Globular Proteins
2003 StandoutNobel
Design, structure and stability of a hyperthermophilic protein variant
1998
Minimotif Miner 3.0: database expansion and significantly improved reduction of false-positive predictions from consensus sequences
2011
Empirical validation of ProteinMPNN’s efficiency in enhancing protein fitness
2024
Local sequence-structure correlations in proteins
1996 StandoutNobel
Alternative splicing of intrinsically disordered regions and rewiring of protein interactions
2013
Computational Library Design for Increasing Haloalkane Dehalogenase Stability
2014 StandoutNobel
The energy landscape of a fast-folding protein mapped by Ala→Gly Substitutions
1997
Conformational analysis of a set of peptides corresponding to the entire primary sequence of the N-terminal domain of the ribosomal protein L9: evidence for stable native-like secondary structure in the unfolded state 1 1Edited by P. E. Wright
1999
A desolvation barrier to hydrophobic cluster formation may contribute to the rate‐limiting step in protein folding
1997 StandoutNobel
Computational protein design
1999
Simultaneous determination of protein structure and dynamics
2005
Denaturant m values and heat capacity changes: Relation to changes in accessible surface areas of protein unfolding
1995 Standout
Optimizing Genetic Circuits by Global Sensitivity Analysis
2004
Conditional disorder in chaperone action
2012
SLiMFinder: a web server to find novel, significantly over-represented, short protein motifs
2010
First principles prediction of protein folding rates 1 1Edited by F. E. Cohen
1999
Is protein folding hierarchic? II. Folding intermediates and transition states
1999
Structure of the cross-β spine of amyloid-like fibrils
2005 StandoutNature
Natively unfolded proteins
2005
Modeling Backbone Flexibility to Achieve Sequence Diversity: The Design of Novel α-Helical Ligands for Bcl-xL
2007
Protein folding in the landscape perspective: Chevron plots and non-arrhenius kinetics
1998
Context-dependent contributions of backbone hydrogen bonding to β-sheet folding energetics
2004 Nature
Design of gene circuits: lessons from bacteria
2004
The coming of age of de novo protein design
2016 StandoutNatureNobel
A practical overview of protein disorder prediction methods
2006
Effect of active site residues in barnase on activity and stability
1992
Chaperonin overexpression promotes genetic variation and enzyme evolution
2009 Nature
Evolutionary conservation of the folding nucleus1 1Edited by A. R. Fersht
2001
Folding Pathway of FKBP12 and Characterisation of the Transition State
1999
Using loop length variants to dissect the folding pathway of a four-helix-bundle protein
1999
Molecular chaperones in protein folding and proteostasis
2011 StandoutNature
Engineered disulfide bonds as probes of the folding pathway of barnase: Increasing the stability of proteins against the rate of denaturation
1993
On the Dependency of Cellular Protein Levels on mRNA Abundance
2016 Standout
ABSINTH: A new continuum solvation model for simulations of polypeptides in aqueous solutions
2008
Evolution of Phosphoregulation: Comparison of Phosphorylation Patterns across Yeast Species
2009
Intrinsically disordered proteins: regulation and disease
2011
The fundamentals of protein folding: bringing together theory and experiment
1999
Temperature adaptation of enzymes: Lessons from laboratory evolution
2001 StandoutNobel
Favourable native-like helical local interactions can accelerate protein folding
1997
Extremely rapid protein folding in the absence of intermediates
1995
Folding kinetics of Che Y mutants with enhanced native α-helix propensities 1 1Edited by A. R. Fersht
1997
Kemp elimination catalysts by computational enzyme design
2008 StandoutNatureNobel
The energy landscape theory of protein folding: Insights into folding mechanisms and scenarios
2000
The G Protein-coupled Receptor Kinase 2 Is a Microtubule-associated Protein Kinase That Phosphorylates Tubulin
1998 StandoutNobel
Improved protein structure prediction using potentials from deep learning
2020 StandoutNatureNobel
A Pattern-Based Method for the Identification of MicroRNA Binding Sites and Their Corresponding Heteroduplexes
2006 Standout
Inferring Function Using Patterns of Native Disorder in Proteins
2007
Enantioselective Enzymes by Computational Design and In Silico Screening
2015 StandoutNobel
Molecular simulations of cotranslational protein folding: fragment stabilities, folding cooperativity and trapping in the ribosome tunnel
2005
Two proteins with the same structure respond very differently to mutation: the role of plasticity in protein stability
2000
Effective energy function for proteins in solution
1999
Specific Nucleus as the Transition State for Protein Folding: Evidence from the Lattice Model
1994
De Novo Evolutionary Emergence of a Symmetrical Protein Is Shaped by Folding Constraints
2016
Folding kinetics of the SH3 domain of PI3 kinase by real-time NMR combined with optical spectroscopy
1998
Protein function space: viewing the limits or limited by our view?
2007
Three key residues form a critical contact network in a protein folding transition state
2001 Nature
Improved Modeling of Side-Chain–Base Interactions and Plasticity in Protein–DNA Interface Design
2012 StandoutNobel
Computational protein design
2001
Molecular collapse: The rate-limiting step in two-state cytochrome c folding
1996
Evolutionary Optimization of Computationally Designed Enzymes: Kemp Eliminases of the KE07 Series
2009 StandoutNobel
The formation of a native-like structure containing eight conserved hydrophobic residues is rate limiting in two-state protein folding of ACBP.
1999
Crystal structure of the µ-opioid receptor bound to a morphinan antagonist
2012 StandoutNatureNobel
Pulsed contractions of an actin–myosin network drive apical constriction
2008 NatureNobel
A molecular dynamics simulation study of segment B1 of protein G
1997
Programmed population control by cell–cell communication and regulated killing
2004 StandoutNatureNobel
PolyQ fibrillation in the cell nucleus: who's bad?
2009
How do small single-domain proteins fold?
1998
Automated Structure- and Sequence-Based Design of Proteins for High Bacterial Expression and Stability
2016
Computational design of receptor and sensor proteins with novel functions
2003 Nature
Negative Autoregulation Speeds the Response Times of Transcription Networks
2002
Quantitative Analysis of Fission Yeast Transcriptomes and Proteomes in Proliferating and Quiescent Cells
2012
Do all backbone polar groups in proteins form hydrogen bonds?
2005
Contact order, transition state placement and the refolding rates of single domain proteins 1 1Edited by P. E. Wright
1998 StandoutNobel
An expanding arsenal of experimental methods yields an explosion of insights into protein folding mechanisms
2009
Sequence determinants of thermodynamic stability in a WW domain—An all‐β‐sheet protein
2009
Folding nucleus: specific of multiple? insights from lattice models and experiments
1998
The interplay between structure and function in intrinsically unstructured proteins
2005
Insights into the regulation of protein abundance from proteomic and transcriptomic analyses
2012 Standout
Estimating the Prevalence of Protein Sequences Adopting Functional Enzyme Folds
2004
Role of conformational sampling in computing mutation‐induced changes in protein structure and stability
2010 StandoutNobel
Backrub-Like Backbone Simulation Recapitulates Natural Protein Conformational Variability and Improves Mutant Side-Chain Prediction
2008
Diminishing returns and tradeoffs constrain the laboratory optimization of an enzyme
2012
Exploring protein fitness landscapes by directed evolution
2009 StandoutNobel
Intrinsic Protein Disorder and Interaction Promiscuity Are Widely Associated with Dosage Sensitivity
2009
NMR chemical shift and relaxation measurements provide evidence for the coupled folding and binding of the p53 transactivation domain
2005
Cellular Strategies for Regulating Functional and Nonfunctional Protein Aggregation
2012
A surprising simplicity to protein folding
2000 StandoutNatureNobel
Why are proteins so robust to site mutations?
2002
SNPs, protein structure, and disease
2001
Rapid Temporal Dynamics of Transcription, Protein Synthesis, and Secretion during Macrophage Activation
2014
Opposing Effects of Glutamine and Asparagine Govern Prion Formation by Intrinsically Disordered Proteins
2011
Global quantification of mammalian gene expression control
2011 StandoutNature
Absolute comparison of simulated and experimental protein-folding dynamics
2002 Nature
Do salt bridges stabilize proteins? A continuum electrostatic analysis
1994
Mutational analysis of acylphosphatase suggests the importance of topology and contact order in protein folding.
1999
Assembly of protein tertiary structures from fragments with similar local sequences using simulated annealing and bayesian scoring functions
1997 StandoutNobel
Evolution favors protein mutational robustness in sufficiently large populations
2007 StandoutNobel
Peptides mediating interaction networks: new leads at last
2006
Identification and application of the concepts important for accurate and reliable protein secondary structure prediction
1996
Engineered gene circuits
2002 Nature
Analysis of protein-protein interactions and the effects of amino acid mutations on their energetics. The importance of water molecules in the binding epitope
1997
Transient Protein-Protein Interactions: Structural, Functional, and Network Properties
2010
Interplay between gene expression noise and regulatory network architecture
2012
Molecular signatures of G-protein-coupled receptors
2013 Nature
Allostery and population shift in drug discovery
2010
The folding of an enzyme
1992
Protein folding dynamics: The diffusion‐collision model and experimental data
1994
Scientific Benchmarks for Guiding Macromolecular Energy Function Improvement
2013 StandoutNobel
An accurate binding interaction model in de novo computational protein design of interactions: If you build it, they will bind
2013
Understanding eukaryotic linear motifs and their role in cell signaling and regulation
2008
Determination of the conformation of folding initiation sites in proteins by computer simulation
1995
Rational engineering of enzyme stability
2004
Phosphate binding sites identification in protein structures
2010
Folding and stability of a fibronectin type III domain of human tenascin
1997
Kinetic role of early intermediates in protein folding
1997
Simple yet functional phosphate-loop proteins
2018 StandoutNobel
Phosphorylation of synaptotagmin I by casein kinase II.
1993 StandoutNobel
Structure–function–folding relationship in a WW domain
2006
De Novo Design of Foldable Proteins with Smooth Folding Funnel
2003
Variational Theory for Site Resolved Protein Folding Free Energy Surfaces
1998
Elastic Effects behind Cooperative Bonding in β-Sheets
2004
Supramolecular Polymerization
2009 Standout
Depletion of casein kinase II by antisense oligonucleotide prevents neuritogenesis in neuroblastoma cells.
1993
The Schizosaccharomyces pombe casein kinase II alpha and beta subunits: evolutionary conservation and positive role of the beta subunit.
1994
Electrostatics significantly affect the stability of designed homeodomain variants
2002
Ab Initio Protein Structure Prediction: Progress and Prospects
2001 StandoutNobel
Φ-Value analysis and the nature of protein-folding transition states
2004
A Theoretical Study of β-Sheet Models:  Is the Formation of Hydrogen-Bond Networks Cooperative?
2002
In the light of directed evolution: Pathways of adaptive protein evolution
2009 StandoutNobel
Structural Features of the GroEL-GroES Nano-Cage Required for Rapid Folding of Encapsulated Protein
2006
The quantitative proteome of a human cell line
2011
Design and chance in the self-assembly of macromolecules
2007
Solution structure and dynamics of a de novo designed three-helix bundle protein
1999
Prediction of protein-folding mechanisms from free-energy landscapes derived from native structures
1999 StandoutNobel
Stability effects of mutations and protein evolvability
2009
Contribution of a Buried Hydrogen Bond to λ Repressor Folding Kinetics
1999
Opportunities and Challenges for Machine Learning-Assisted Enzyme Engineering
2024 Nobel
Internal Stark Effect Measurement of the Electric Field at the Amino Terminus of an α Helix
1992 Science
A theoretical search for folding/unfolding nuclei in three-dimensional protein structures
1999
Fragment Reconstitution of a Small Protein:  Disulfide Mutant of a Short C-Terminal Fragment Derived from Streptococcal Protein G
1999
Landscape approaches for determining the ensemble of folding transition states: Success and failure hinge on the degree of frustration
2000
The Folding Kinetics and Thermodynamics of the Fyn-SH3 Domain
1998
De Novo Protein Design: Fully Automated Sequence Selection
1997 Science
Structure of the transition state for folding of the 129 aa protein CheY resembles that of a smaller protein, CI-2
1996
Proteome-Wide Discovery of Evolutionary Conserved Sequences in Disordered Regions
2012
Reprogramming homing endonuclease specificity through computational design and directed evolution
2013 StandoutNobel
Cylindrical β-Sheet Peptide Assemblies
1998
Unfolded Proteins and Protein Folding Studied by NMR
2004
Classification of Intrinsically Disordered Regions and Proteins
2014 Standout
The Structure of the Potassium Channel: Molecular Basis of K + Conduction and Selectivity
1998 StandoutScienceNobel
Long-range order in the src SH3 folding transition state
2000 StandoutNobel
Prediction and measurement of an autoregulatory genetic module
2003
Unifying features in protein-folding mechanisms
2003
Recent improvements in prediction of protein structure by global optimization of a potential energy function
2001
Optimization of rates of protein folding: the nucleation-condensation mechanism and its implications.
1995
Folding of Circular and Permuted Chymotrypsin Inhibitor 2:  Retention of the Folding Nucleus
1998
Mining α-Helix-Forming Molecular Recognition Features with Cross Species Sequence Alignments
2007
Short Linear Motifs: Ubiquitous and Functionally Diverse Protein Interaction Modules Directing Cell Regulation
2014
Stochastic Gene Expression in a Single Cell
2002 StandoutScience
Design of a Novel Globular Protein Fold with Atomic-Level Accuracy
2003 StandoutScienceNobel
Use of a Designed Triple-Stranded Antiparallel β-Sheet To Probe β-Sheet Cooperativity in Aqueous Solution
1998
Exploring the origins of topological frustration: Design of a minimally frustrated model of fragment B of protein A
1999
Genetic circuit building blocks for cellular computation, communications, and signal processing
2003
What RNA World? Why a Peptide/RNA Partnership Merits Renewed Experimental Attention
2015
Protein Structure Prediction and Structural Genomics
2001 StandoutScienceNobel
Characterization of Molecular Recognition Features, MoRFs, and Their Binding Partners
2007
The order of secondary structure elements does not determine the structure of a protein but does affect its folding kinetics
1995
Correlation of mRNA and protein abundance in the developing maize leaf
2014
Protein Dynamism and Evolvability
2009 Science
Absolute quantification of microbial proteomes at different states by directed mass spectrometry
2011
Protein Annotation at Genomic Scale:  The Current Status
2007
Φ-Value analysis by molecular dynamics simulations of reversible folding
2005
Diffusion control in an elementary protein folding reaction
1997
Intrinsically disordered C-terminal segments of voltage-activated potassium channels: a possible fishing rod-like mechanism for channel binding to scaffold proteins
2006
Synthetic Gene Circuits: Design with Directed Evolution
2007 StandoutNobel
The 3D profile method for identifying fibril-forming segments of proteins
2006 StandoutNobel
A more precise characterization of chaperonin substrates
2010
Computational Design of Virus-Like Protein Assemblies on Carbon Nanotube Surfaces
2011 Science
A simple model for calculating the kinetics of protein folding from three-dimensional structures
1999
Coupled prediction of protein secondary and tertiary structure
2003 StandoutNobel
Update 1 of: Computational Modeling Approaches to Structure–Function Analysis of G Protein-Coupled Receptors
2011
Forces contributing to the conformational stability of proteins
1996
Directed evolution methods for overcoming trade‐offs between protein activity and stability
2019
Folding Dynamics of the src SH3 Domain
1997 StandoutNobel
The identification of short linear motif-mediated interfaces within the human interactome
2012
Identification of two DNA-binding sites on the globular domain of histone H5.
1996 StandoutNobel
Folding and Binding of an Intrinsically Disordered Protein: Fast, but Not ‘Diffusion-Limited’
2013
Computational Design of Stable and Soluble Biocatalysts
2018
Top-down design of protein architectures with reinforcement learning
2023 StandoutScienceNobel
Engineered bidirectional communication mediates a consensus in a microbial biofilm consortium
2007 StandoutNobel
Genetic analysis of cell morphogenesis in fission yeast--a role for casein kinase II in the establishment of polarized growth.
1994 StandoutNobel
The Protein Folding Problem
2008
Structure comparison of human glioma pathogenesis-related protein GliPR and the plant pathogenesis-related protein P14a indicates a functional link between the human immune system and a plant defense system
1998 StandoutNobel
System wide analyses have underestimated protein abundances and the importance of transcription in mammals
2014
Transition state heterogeneity in GCN4 coiled coil folding studied by using multisite mutations and crosslinking
1999
The Schizosaccharomyces pombe casein kinase II α and β subunits: evolutionary conservation and positive role of the β subunit
1994
Cooperativity in protein-folding kinetics.
1993
Hints of Nonhierarchical Folding of Acidic Fibroblast Growth Factor
2002
Creation of a Pair of Stereochemically Complementary Biocatalysts
2006
De novo design of protein logic gates
2020 StandoutScienceNobel
Design of artificial cell–cell communication using gene and metabolic networks
2004
Cooperative Interaction between the Three Strands of a Designed Antiparallel β-Sheet
1998
A simple physical model for binding energy hot spots in protein–protein complexes
2002 StandoutNobel
Modulating protein stability – directed evolution strategies for improved protein function
2013

Works of Luís Serrano being referenced

Prediction of water and metal binding sites and their affinities by using the Fold-X force field
2005
Control of Drosophila Gastrulation by Apical Localization of Adherens Junctions and RhoGEF2
2007 Science
Transcriptome Complexity in a Genome-Reduced Bacterium
2009 Science
Structural and functional protein network analyses predict novel signaling functions for rhodopsin
2011
Quantification of mRNA and protein and integration with protein turnover in a bacterium
2011
Specificity and Evolvability in Eukaryotic Protein Interaction Networks
2007
Strength and co-operativity of contributions of surface salt bridges to protein stability
1990
Local versus nonlocal interactions in protein folding and stability –  an experimentalist's point of view
1996
Intrinsic secondary structure propensities of the amino acids, using statistical ϕ–ψ matrices: Comparison with experimental scales
1994
Helix design, prediction and stability
1995
The folding of an enzyme
1992
Comparative Genomics and Disorder Prediction Identify Biologically Relevant SH3 Protein Interactions
2005
Protein design with fragment databases
2011
Genome-Wide Prediction of SH2 Domain Targets Using Structural Information and the FoldX Algorithm
2008
Conformational Analysis of Peptides Corresponding to β-Hairpins and a β-Sheet that Represent the Entire Sequence of the α-Spectrin SH3 Domain
1996
Engineering stability in gene networks by autoregulation
2000 Nature
Structure of the transition state in the folding process of human procarboxypeptidase A2 activation domain
1998
Structural analysis of peptides encompassing all α-helices of three α/β parallel proteins: Che-Y, flavodoxin and P21-Ras: Implications for α-Helix stability and the folding of α/β parallel proteins
1995
How Protein Stability and New Functions Trade Off
2008
A tale of two secondary structure elements: when a β-hairpin becomes an α-helix 1 1Edited by A. R. Fersht
1999
Loop length, intramolecular diffusion and protein folding
1997
Protein aggregation and amyloidosis: confusion of the kinds?
2006
Point Mutations in Protein Globular Domains: Contributions from Function, Stability and Misfolding
2006
Rational design of a GCN4-derived mimetic of interleukin-4.
1999
Different folding transition states may result in the same native structure
1996
Computational estimation of specific side chain interaction energies in α helices
2001
Energy estimation in protein design
2002
α-Helix stability in proteins
1992
1H‐ and15N‐NMR assignment and solution structure of the chemotacticEscherichia coliChe Y protein
1993
Step-wise Mutation of Barnase to Binase
1993
Exploring the sequence determinants of amyloid structure using position-specific scoring matrices
2010
Formation and stability of β-hairpin structures in polypeptides
1998
Conformational analysis of peptides corresponding to all the secondary structure elements of protein L B1 domain: Secondary structure propensities are not conserved in proteins with the same fold
1997
PepX: a structural database of non-redundant protein–peptide complexes
2009
De novo design and structural analysis of a model β-hairpin peptide system
1996
The folding of an enzyme
1992
Towards Cellular Systems in 4D
2005
An NMR View of the Folding Process of a CheY Mutant at the Residue Level
2002
Thermodynamic and Kinetic Analysis of the SH3 Domain of Spectrin Shows a Two-State Folding Transition
1994
Effect of alanine versus glycine in α-helices on protein stability
1992 Nature
Advancing Cell Biology Through Proteomics in Space and Time (PROSPECTS)
2012
Evidence for a Two-State Transition in the Folding Process of the Activation Domain of Human Procarboxypeptidase A2
1995
The Ubiquitin Domain Superfold: Structure-based Sequence Alignments and Characterization of Binding Epitopes
2005
Folding of Protein G B1 Domain Studied by the Conformational Characterization of Fragments Comprising Its Secondary Structure Elements
1995
The folding of an enzyme
1992
Analysis of Disease-Linked Rhodopsin Mutations Based on Structure, Function, and Protein Stability Calculations
2010
A Thermodynamic and Kinetic Analysis of the Folding Pathway of an SH3 Domain Entropically Stabilised by a Redesigned Hydrophobic Core
2003
Analysis of the effect of local interactions on protein stability
1996
A Comparative Study of the Relationship Between Protein Structure and β-Aggregation in Globular and Intrinsically Disordered Proteins
2004
Structures in systems biology
2007
Computer-aided design of a PDZ domain to recognize new target sequences
2002
The relationship between sequence and structure in elementary folding units
2000
Histidine residues at the N- and C-termini of .alpha.-helixes: perturbed pKas and protein stability
1992
Similarities between the spectrin SH3 domain denatured state and its folding transition state11Edited by A. R. Fersht
2000
How Evolutionary Pressure Against Protein Aggregation Shaped Chaperone Specificity
2005
Transient folding intermediates characterized by protein engineering
1990 Nature
Calculation of Mutational Free Energy Changes in Transition States for Protein Folding
2003
1H and 15N NMR assignment and solution structure of the SH3 domain of spectrin: Comparison of unrefined and refined structure sets with the crystal structure
1997
Conformational strain in the hydrophobic core and its implications for protein folding and design
2002
Systematic Discovery of New Recognition Peptides Mediating Protein Interaction Networks
2005
Association of casein kinase II with microtubules
1989
Predicting Changes in the Stability of Proteins and Protein Complexes: A Study of More Than 1000 Mutations
2002
The folding of an enzyme
1992
Investigating the Structural Determinants of the p21-like Triphosphate and Mg2+Binding Site
1995
Structure-Based DNA-Binding Prediction and Design
2010
Engineering Signal Transduction Pathways
2010
Elucidating the Folding Problem of Helical Peptides using Empirical Parameters. III>Temperature and pH Dependence
1995
Correlation of mRNA and protein in complex biological samples
2009
Obligatory steps in protein folding and the conformational diversity of the transition state
1998
A Genome-wide Ras-Effector Interaction Network
2007
The SH3-fold Family: Experimental Evidence and Prediction of Variations in the Folding Pathways
2000
The Stability Effects of Protein Mutations Appear to be Universally Distributed
2007
Analyzing Protein Interaction Networks Using Structural Information
2008
Conformational Exchange on the Microsecond Time Scale in α-Helix and β-Hairpin Peptides Measured by 13C NMR Transverse Relaxation
2001
Three-dimensional structure of chemotactic che Y protein in aqueous solution by nuclear magnetic resonance methods
1995
Principles of protein stability derived from protein engineering experiments
1993
Phosphorylation of a neuronal-specific beta-tubulin isotype.
1990
Design of a 20-Amino Acid, Three-Stranded β-Sheet Protein
1998 Science
Tubulin phosphorylation by casein kinase II is similar to that found in vivo.
1987
Structure-Based Assembly of Protein Complexes in Yeast
2004 Science
The multiple‐specificity landscape of modular peptide recognition domains
2011
Sequence determinants of amyloid fibril formation
2003
A casein kinase II-related activity is involved in phosphorylation of microtubule-associated protein MAP-1B during neuroblastoma cell differentiation.
1988
Rankless by CCL
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