Citation Impact
Citing Papers
Selective targeting of engineered T cells using orthogonal IL-2 cytokine-receptor complexes
2018 StandoutScienceNobel
Preferential Generation of Follicular B Helper T Cells from Foxp3 + T Cells in Gut Peyer's Patches
2009 StandoutScienceNobel
CTLA-4 Control over Foxp3 + Regulatory T Cell Function
2008 StandoutScienceNobel
Control of Regulatory T Cell Development by the Transcription Factor Foxp3
2003 StandoutScienceNobel
A noninflammatory mRNA vaccine for treatment of experimental autoimmune encephalomyelitis
2021 StandoutScienceNobel
Dendritic cell–expanded, islet-specific CD4+ CD25+ CD62L+ regulatory T cells restore normoglycemia in diabetic NOD mice
2007 StandoutNobel
A sex-biased imbalance between Tfr, Tph, and atypical B cells determines antibody responses in COVID-19 patients
2023 StandoutNobel
Regulatory T cells suppress tumor-specific CD8 T cell cytotoxicity through TGF-β signals in vivo
2004
The microbiota regulates type 2 immunity through RORγt + T cells
2015 StandoutScienceNobel
Migration matters: regulatory T-cell compartmentalization determines suppressive activity in vivo
2005
PD-1 + regulatory T cells amplified by PD-1 blockade promote hyperprogression of cancer
2019 StandoutNobel
Aire-Dependent Thymic Development of Tumor-Associated Regulatory T Cells
2013 StandoutScienceNobel
Effective expansion of alloantigen-specific Foxp3 + CD25 + CD4 + regulatory T cells by dendritic cells during the mixed leukocyte reaction
2006 StandoutNobel
Cutting Edge: Cure of Colitis by CD4+CD25+ Regulatory T Cells
2003
Differentiation and Expansion of T Cells with Regulatory Function from Human Peripheral Lymphocytes by Stimulation in the Presence of TGF-β
2005
Hallmarks of Cancer: The Next Generation
2011 Standout
The role of the graft in establishing tolerance
2002
From Vanilla to 28 Flavors: Multiple Varieties of T Regulatory Cells
2006
Treg and CTLA-4: Two intertwining pathways to immune tolerance
2013
Tr1 cells: From discovery to their clinical application
2006
Homing to suppress: address codes for Treg migration
2005
Infectious tolerance and the long‐term acceptance of transplanted tissue
2006
Regulatory T Cells in Cancer
2010
Foxp3 controls regulatory T-cell function by interacting with AML1/Runx1
2007 StandoutNatureNobel
The promise of low-dose interleukin-2 therapy for autoimmune and inflammatory diseases
2015
Regulatory T Cells and Immune Tolerance
2008 StandoutNobel
T Follicular Helper Cell Differentiation, Function, and Roles in Disease
2014
Preferential loss of IL‐2–secreting CD4+ T helper cells in chronic HCV infection†
2005
Suppression by TFR cells leads to durable and selective inhibition of B cell effector function
2016
CTLA4 blockade and GM-CSF combination immunotherapy alters the intratumor balance of effector and regulatory T cells
2006
Differentiation and function of Foxp3+ effector regulatory T cells
2012
Dynamic regulation of T follicular regulatory cell responses by interleukin 2 during influenza infection
2017
TGF-β-dependent mechanisms mediate restoration of self-tolerance induced by antibodies to CD3 in overt autoimmune diabetes
2003
Prospects for a vaccine against the hepatitis C virus
2005 StandoutNatureNobel
The regulation of immune tolerance by FOXP3
2017
Recipient-type specific CD4+CD25+ regulatory T cells favor immune reconstitution and control graft-versus-host disease while maintaining graft-versus-leukemia
2003
Immune Checkpoint Targeting in Cancer Therapy: Toward Combination Strategies with Curative Potential
2015 StandoutNobel
Role of CD4+CD25+ regulatory T cells from naive host thymus in the induction of acquired transplant tolerance by immunization with allo-major histocompatibility complex peptide.1
2003
Th17: An Effector CD4 T Cell Lineage with Regulatory T Cell Ties
2006
Induction of transplantation tolerance—the potential of regulatory T cells
2005
Thymic Commitment of Regulatory T Cells Is a Pathway of TCR-Dependent Selection That Isolates Repertoires Undergoing Positive or Negative Selection
2005
Regulatory T Cells Control Antigen-Specific Expansion of Tfh Cell Number and Humoral Immune Responses via the Coreceptor CTLA-4
2014 StandoutNobel
Follicular regulatory T cells can be specific for the immunizing antigen and derive from naive T cells
2016
Taking dendritic cells into medicine
2007 StandoutNatureNobel
Regulatory T cells in transplantation tolerance
2003 StandoutNobel
The receptor PD-1 controls follicular regulatory T cells in the lymph nodes and blood
2012
Alloantigen-presenting plasmacytoid dendritic cells mediate tolerance to vascularized grafts
2006
Multiple treg suppressive modules and their adaptability
2012 StandoutNobel
The role of regulatory T cells in controlling immunologic self-tolerance
2003 StandoutNobel
Regulatory T cells under scrutiny
2003
Induction of antigen-specific immunologic tolerance by in vivo and in vitro antigen-specific expansion of naturally arising Foxp3+CD25+CD4+ regulatory T cells
2004 StandoutNobel
Plasticity of Foxp3+ T Cells Reflects Promiscuous Foxp3 Expression in Conventional T Cells but Not Reprogramming of Regulatory T Cells
2012
Distinct Cellular Mechanisms Underlie Anti-CTLA-4 and Anti-PD-1 Checkpoint Blockade
2017 StandoutNobel
FoxP3+ regulatory T cells promote influenza-specific Tfh responses by controlling IL-2 availability
2014
Regulatory T cells and intestinal homeostasis
2005
The Immunobiology of Inductive Anti-CD40L Therapy in Transplantation: Allograft Acceptance is Not Dependent Upon the Deletion of Graft-Reactive T Cells
2002
Interleukin‐10‐secreting type 1 regulatory T cells in rodents and humans
2006
IL-21 restricts T follicular regulatory T cell proliferation through Bcl-6 mediated inhibition of responsiveness to IL-2
2017
Loss of IFN-γ Pathway Genes in Tumor Cells as a Mechanism of Resistance to Anti-CTLA-4 Therapy
2016 StandoutNobel
Role of LAG-3 in Regulatory T Cells
2004
Mechanisms of suppression by suppressor T cells
2005
A rheostat for immune responses: the unique properties of PD-1 and their advantages for clinical application
2013 StandoutNobel
Dendritic Cells and CD4+CD25+ T Regulatory Cells: Crosstalk Between Two Professionals in Immunity versus Tolerance
2006
CD40L Blockade Prevents Autoimmune Diabetes by Induction of Bitypic NK/DC Regulatory Cells
2002
TCR stimulation with modified anti-CD3 mAb expands CD8+ T cell population and induces CD8+CD25+ Tregs
2005
Human FOXP3+ Regulatory T Cell Heterogeneity and Function in Autoimmunity and Cancer
2019 StandoutNobel
The Coinhibitory Receptor CTLA-4 Controls B Cell Responses by Modulating T Follicular Helper, T Follicular Regulatory, and T Regulatory Cells
2014
Peripheral and Intestinal Regulatory CD4+CD25high T Cells in Inflammatory Bowel Disease
2005
Circulating Follicular Regulatory T Cells Are Defective in Multiple Sclerosis
2015
Recruitment of Foxp3+ T regulatory cells mediating allograft tolerance depends on the CCR4 chemokine receptor
2005
Naturally Arising CD4+Regulatory T Cells for Immunologic Self -Tolerance and Negative Control of Immune Responses
2003 StandoutNobel
Attenuation of CD8+ T-Cell Function by CD4+CD25+ Regulatory T Cells in B-Cell Non-Hodgkin's Lymphoma
2006
Dendritic cells with TGF-β1 differentiate naïve CD4+CD25−T cells into islet-protective Foxp3+regulatory T cells
2007 StandoutNobel
Sialyl Lewis x (CD15s) identifies highly differentiated and most suppressive FOXP3 high regulatory T cells in humans
2015 StandoutNobel
CD4+CD25−LAG3+regulatory T cells controlled by the transcription factor Egr-2
2009 StandoutNobel
Regulatory T Cells and Human Disease
2020 StandoutNobel
Neuropilin 1 is expressed on thymus-derived natural regulatory T cells, but not mucosa-generated induced Foxp3+ T reg cells
2012
Immune Responses in Healthy and Allergic Individuals Are Characterized by a Fine Balance between Allergen-specific T Regulatory 1 and T Helper 2 Cells
2004
Differential Regulatory Capacity of CD25+ T Regulatory Cells and Preactivated CD25+ T Regulatory Cells on Development, Functional Activation, and Proliferation of Th2 Cells
2004
Cutting Edge: CD4+CD25+ Alloantigen-Specific Immunoregulatory Cells That Can Prevent CD8+ T Cell-Mediated Graft Rejection: Implications for Anti-CD154 Immunotherapy
2002
Incomplete Depletion and Rapid Regeneration of Foxp3+ Regulatory T Cells Following Anti-CD25 Treatment in Malaria-Infected Mice
2007
The role of the graft in establishing tolerance
2002
CD4+ follicular regulatory T cells optimize the influenza virus–specific B cell response
2020
Nonoverlapping roles of PD-1 and FoxP3 in maintaining immune tolerance in a novel autoimmune pancreatitis mouse model
2016 StandoutNobel
Differentiation of Tr1 cells by immature dendritic cells requires IL-10 but not CD25+CD4+ Tr cells
2004
A functionally specialized population of mucosal CD103+ DCs induces Foxp3+ regulatory T cells via a TGF-β– and retinoic acid–dependent mechanism
2007 Standout
The origins, function, and regulation of T follicular helper cells
2012
T follicular regulatory cells
2016
CD4+CD25bright T Cells in Human Intestinal Lamina Propria as Regulatory Cells
2004
In Vitro–expanded Antigen-specific Regulatory T Cells Suppress Autoimmune Diabetes
2004
Simultaneous inhibition of two regulatory T-cell subsets enhanced Interleukin-15 efficacy in a prostate tumor model
2012 StandoutNobel
SLAP Deficiency Enhances Number and Function of Regulatory T Cells Preventing Chronic Autoimmune Arthritis in SKG Mice
2011 StandoutNobel
IL-10–producing and naturally occurring CD4+ Tregs: limiting collateral damage
2004
Expression of the integrin αEβ7identifies unique subsets of CD25+as well as CD25−regulatory T cells
2002
Immunologic and clinical effects of antibody blockade of cytotoxic T lymphocyte-associated antigen 4 in previously vaccinated cancer patients
2008 StandoutNobel
CD4+regulatory cells as a potential immunotherapy
2005 StandoutNobel
Induction of autoimmune disease by deletion of CTLA-4 in mice in adulthood
2016 StandoutNobel
Foxp3+natural regulatory T cells preferentially form aggregates on dendritic cellsin vitroand actively inhibit their maturation
2008 StandoutNobel
All-trans retinoic acid mediates enhanced T reg cell growth, differentiation, and gut homing in the face of high levels of co-stimulation
2007
Alloantigen-Induced CD25+CD4+ Regulatory T Cells Can Develop In Vivo from CD25−CD4+ Precursors in a Thymus-Independent Process
2004
Glycolipid α-C-galactosylceramide is a distinct inducer of dendritic cell function during innate and adaptive immune responses of mice
2006 StandoutNobel
Emerging Challenges in Regulatory T Cell Function and Biology
2007 StandoutScienceNobel
Control of foreign Ag‐specific Ab responses by Treg and Tfr
2020 StandoutNobel
Dendritic cells expand antigen‐specific Foxp3+CD25+CD4+ regulatory T cells including suppressors of alloreactivity
2006 StandoutNobel
Decreased T Follicular Regulatory Cell/T Follicular Helper Cell (TFH) in Simian Immunodeficiency Virus–Infected Rhesus Macaques May Contribute to Accumulation of TFH in Chronic Infection
2015
Follicular Helper T Cells
2016
Induced CD4+Foxp3+Regulatory T Cells in Immune Tolerance
2012
Anti-CCR4 mAb selectively depletes effector-type FoxP3+CD4+regulatory T cells, evoking antitumor immune responses in humans
2013 StandoutNobel
Spatial distribution and function of T follicular regulatory cells in human lymph nodes
2018
BALB/c mice have more CD4+CD25+ T regulatory cells and show greater susceptibility to suppression of their CD4+CD25− responder T cells than C57BL/6 mice
2005
PD-1 and CTLA-4 combination blockade expands infiltrating T cells and reduces regulatory T and myeloid cells within B16 melanoma tumors
2010 StandoutNobel
CTLA-4 controls follicular helper T-cell differentiation by regulating the strength of CD28 engagement
2014
Treg-expressed CTLA-4 depletes CD80/CD86 by trogocytosis, releasing free PD-L1 on antigen-presenting cells
2021 StandoutNobel
Immunotherapy: Bewitched, Bothered, and Bewildered No More
2004 StandoutScienceNobel
Foxp3+ Treg cells in humoral immunity
2013 StandoutNobel
In vivo expansion of T reg cells with IL-2–mAb complexes: induction of resistance to EAE and long-term acceptance of islet allografts without immunosuppression
2009
Regulatory roles of IL-10–producing human follicular T cells
2019 StandoutNobel
Cutting Edge: Recipient MHC Class II Expression Is Required to Achieve Long-Term Survival of Murine Cardiac Allografts After Costimulatory Blockade
2001
Follicular regulatory T cells control humoral autoimmunity via NFAT2-regulated CXCR5 expression
2014
TCR-based lineage tracing: no evidence for conversion of conventional into regulatory T cells in response to a natural self-antigen in pancreatic islets
2007
A distinct subpopulation of CD25−T-follicular regulatory cells localizes in the germinal centers
2017 StandoutNobel
Mitochondrial activation chemicals synergize with surface receptor PD-1 blockade for T cell-dependent antitumor activity
2017 StandoutNobel
Exploiting Tolerance Processes in Transplantation
2004 Science
Analysis of the Underlying Cellular Mechanisms of Anti-CD154-Induced Graft Tolerance: The Interplay of Clonal Anergy and Immune Regulation
2005 StandoutNobel
Natural and Induced CD4+CD25+ Cells Educate CD4+CD25− Cells to Develop Suppressive Activity: The Role of IL-2, TGF-β, and IL-10
2004
Regulatory T Cells Induced by 1α,25-Dihydroxyvitamin D3 and Mycophenolate Mofetil Treatment Mediate Transplantation Tolerance
2001
Antigen-specific peripheral shaping of the natural regulatory T cell population
2008
Characterization of Foxp3+CD4+CD25+ and IL-10-Secreting CD4+CD25+ T Cells during Cure of Colitis
2006 StandoutNobel
Differential control of human Treg and effector T cells in tumor immunity by Fc-engineered anti–CTLA-4 antibody
2018 StandoutNobel
Programmed death 1 ligand signaling regulates the generation of adaptive Foxp3 + CD4 + regulatory T cells
2008
Continuous Activation of Autoreactive CD4+ CD25+ Regulatory T Cells in the Steady State
2003
Works of Luís Graça being referenced
T follicular helper and T follicular regulatory cells have different TCR specificity
2017
Modulation of IL-17 and Foxp3 Expression in the Prevention of Autoimmune Arthritis in Mice
2010
Dominant transplantation tolerance
2003
Critical Influence of Natural Regulatory CD25+ T Cells on the Fate of Allografts in the Absence of Immunosuppression
2005
Regulatory T cells in transplantation
2006
Identification of Foxp3+ T Follicular Regulatory (Tfr) Cells by Flow Cytometry
2015
Regulatory T cells and dendritic cells in transplantation tolerance: molecular markers and mechanisms
2003
Serial analysis of gene expression provides new insights into regulatory T cells
2003
T follicular helper cells and T follicular regulatory cells in rheumatic diseases
2019
Dominant tolerance: activation thresholds for peripheral generation of regulatory T cells
2005
Directed differentiation of dendritic cells from mouse embryonic stem cells
2000
Dominant transplantation tolerance impairs CD8+ T cell function but not expansion
2002
Identification of Regulatory T Cells in Tolerated Allografts
2002
Regulatory T Cells Overexpress a Subset of Th2 Gene Transcripts
2002
Cutting Edge: Anti-CD154 Therapeutic Antibodies Induce Infectious Transplantation Tolerance
2000
Regulatory T cells in the induction and maintenance of peripheral transplantation tolerance.
2003
Donor-specific transplantation tolerance: The paradoxical behavior of CD4+CD25+T cells
2004
The Ratio of Blood T Follicular Regulatory Cells to T Follicular Helper Cells Marks Ectopic Lymphoid Structure Formation While Activated Follicular Helper T Cells Indicate Disease Activity in Primary Sjögren's Syndrome
2018
Regulatory T cells in the induction and maintenance of peripheral transplantation tolerance
2003
Regulation of the Germinal Center Reaction by Foxp3+ Follicular Regulatory T Cells
2011
Human blood T fr cells are indicators of ongoing humoral activity not fully licensed with suppressive function
2017
Induction offoxP3+ Regulatory T Cells in the Periphery of T Cell Receptor Transgenic Mice Tolerized to Transplants
2004
Both CD4+CD25+ and CD4+CD25− Regulatory Cells Mediate Dominant Transplantation Tolerance
2002
Identification of Regulatory Foxp3+ Invariant NKT Cells Induced by TGF-β
2010