Citation Impact
Citing Papers
Ferroptosis regulation by the NGLY1/NFE2L1 pathway
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Induced Pluripotent Stem Cells Generated from Patients with ALS Can Be Differentiated into Motor Neurons
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Peroxynitrite Inhibits T Lymphocyte Activation and Proliferation by Promoting Impairment of Tyrosine Phosphorylation and Peroxynitrite-Driven Apoptotic Death
1999
Mutant Copper-Zinc Superoxide Dismutase (SOD1) Induces Protein Secretion Pathway Alterations and Exosome Release in Astrocytes
2013
Ionotropic Glutamate Receptors & CNS Disorders
2008
Antioxidant Therapy: A New Pharmacological Approach in Shock, Inflammation, and Ischemia/Reperfusion Injury
2001
Nitric oxide induces tau hyperphosphorylation via glycogen synthase kinase‐3β activation
2005
Recent studies on dendrotoxins and potassium ion channels
1997
Molecular cloning and characterization of the rat NMDA receptor
1991 StandoutNature
Apoptosis in the nervous system
2000 StandoutNature
The physiology and pathophysiology of nitric oxide in the brain
2005
Molecular identification of a renal urate–anion exchanger that regulates blood urate levels
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Mechanisms and Functional Implications of Adult Neurogenesis
2008 Standout
Memantine in Moderate-to-Severe Alzheimer's Disease
2003 Standout
Rapid and Irreversible Inactivation of Protein Tyrosine Phosphatases PTP1B, CD45, and LAR by Peroxynitrite
1999
The Ubiquitin Proteasome System in Neurodegenerative Diseases
2003 StandoutNobel
Physiological and pathophysiological roles of nitric oxide in the central nervous system
1996
Involvement of the mitogen-activated protein kinase cascade in peroxynitrite-mediated arachidonic acid release in vascular smooth muscle cells
2004
Proteolytic Processing of Amyloid-β Precursor Protein by Secretases Does Not Require Cell Surface Transport
2004 StandoutNobel
p130cas is a cellular target protein for tyrosine nitration induced by peroxynitrite
1999
Characterization of nitroproteome in neuron‐like PC12 cells differentiated with nerve growth factor: Identification of two nitration sites in α‐tubulin
2005
X-Ray Structure of Acid-Sensing Ion Channel 1–Snake Toxin Complex Reveals Open State of a Na+-Selective Channel
2014 StandoutNobel
Transgenics, toxicity and therapeutics in rodent models of mutant SOD1-mediated familial ALS
2008
Nitric oxide, cell bioenergetics and neurodegeneration
2006
Channel opening and gating mechanism in AMPA-subtype glutamate receptors
2017 StandoutNatureNobel
Activation of microglial NADPH oxidase is synergistic with glial iNOS expression in inducing neuronal death: a dual-key mechanism of inflammatory neurodegeneration
2005
Mechanisms Underlying Inflammation in Neurodegeneration
2010 Standout
Cell signaling by reactive nitrogen and oxygen species in atherosclerosis
2000
A nitric oxide donor induces neurogenesis and reduces functional deficits after stroke in rats
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Enhancing Mitochondrial Calcium Buffering Capacity Reduces Aggregation of Misfolded SOD1 and Motor Neuron Cell Death without Extending Survival in Mouse Models of Inherited Amyotrophic Lateral Sclerosis
2013
Peroxynitrite Targets the Epidermal Growth Factor Receptor, Raf-1, and MEK Independently to Activate MAPK
2000
Glial cells as intrinsic components of non-cell-autonomous neurodegenerative disease
2007
Triggering and modulation of apoptosis by oxidative stress
2000 Standout
Non-Cell-Autonomous Effect of Human SOD1G37R Astrocytes on Motor Neurons Derived from Human Embryonic Stem Cells
2008
Peroxynitrite Induces Covalent Dimerization of Epidermal Growth Factor Receptors in A431 Epidermoid Carcinoma Cells
1998
Role of nitric oxide in Parkinson's disease
2005
Peroxynitrite scavenging by metalloporphyrins and thiolates
2000
Peroxynitrite-induced cytotoxicity: mechanism and opportunities for intervention
2003
ALS: A Disease of Motor Neurons and Their Nonneuronal Neighbors
2006
The Protective Effects of Estrogen on the Cardiovascular System
1999 Standout
Peroxynitrite-Induced Neuronal Apoptosis Is Mediated by Intracellular Zinc Release and 12-Lipoxygenase Activation
2004
Mitochondrial Dysfunction and Glaucoma
2009
The chemical nature of the main central excitatory transmitter: A critical appraisal based upon release studies and synaptic vesicle localization
1993
Octopamine Regulates Sleep inDrosophilathrough Protein Kinase A-Dependent Mechanisms
2008
Neuroprotective efficacy and therapeutic time window of peroxynitrite decomposition catalysts in focal cerebral ischemia in rats#
2004
Fasciculin inhibition of acetylcholinesterase is prevented by chemical modification of the enzyme at a peripheral site
1994
The Role of Immune and Inflammatory Mechanisms in ALS
2011
Tyrosine nitration: Localisation, quantification, consequences for protein function and signal transduction
2001
Ca2+/Calmodulin Kinase-dependent Activation of Hypoxia Inducible Factor 1 Transcriptional Activity in Cells Subjected to Intermittent Hypoxia
2004 StandoutNobel
Unraveling peroxynitrite formation in biological systems
2001
Nitric oxide synthase expression in cervical spinal cord in sporadic amyotrophic lateral sclerosis
1998
Opposite Roles of Selenium-dependent Glutathione Peroxidase-1 in Superoxide Generator Diquat- and Peroxynitrite-induced Apoptosis and Signaling
2001
Biology of nitric oxide signaling
2000
Nitric Oxide and Peroxynitrite in Health and Disease
2007 Standout
Phosphatidylinositol 3-Kinase Is a Target for Protein Tyrosine Nitration
1998
Decoding ALS: from genes to mechanism
2016 StandoutNature
Oxidative stress in neurodegenerative diseases: therapeutic implications for superoxide dismutase mimetics
2003
Biological aspects of reactive nitrogen species
1999
Two distinct signaling pathways regulate peroxynitrite-induced apoptosis in PC12 cells
2006
Peroxynitrite modulates acidic fibroblast growth factor (FGF-1) activity
2003
DNA Damage Induced by Peroxynitrite: Subsequent Biological Effects
1997
Reactive oxygen species trigger motoneuron death in non-cell-autonomous models of ALS through activation of c-Abl signaling
2015
Glia and pain: Is chronic pain a gliopathy?
2013
Mechanisms of Peroxynitrite Decomposition Catalyzed by FeTMPS, a Bioactive Sulfonated Iron Porphyrin
2001
Nitric Oxide and Peroxynitrite Interactions with Mitochondria
2002
Neurodegenerative disorders: the role of peroxynitrite
1999
Peroxynitrite Formation During Rat Hepatic Allograft Rejection
1999
Astrocytes as determinants of disease progression in inherited amyotrophic lateral sclerosis
2008
The neuronal toxicity of sulfite plus peroxynitrite is enhancede by glutathione depletion: implications for Parkinson’s disease
1999
Connexin-43 induces chemokine release from spinal cord astrocytes to maintain late-phase neuropathic pain in mice
2014
Short Neuropeptide F Is a Sleep-Promoting Inhibitory Modulator
2013 StandoutNobel
Peroxynitrite Modulates the Activation of p38 and Extracellular Regulated Kinases in PC12 Cells
2000
Prevention of Peroxynitrite-induced Apoptosis of Motor Neurons and PC12 Cells by Tyrosine-containing Peptides
2007
Regulation of Tau Pathology by the Microglial Fractalkine Receptor
2010
Extensive co‐occurrence of substance P and dynorphin in striatal projection neurons: An evolutionarily conserved feature of basal ganglia organization
1990
Tyrosine nitration by superoxide and nitric oxide fluxes in biological systems: Modeling the impact of superoxide dismutase and nitric oxide diffusion
2005
Cerebrospinal fluid levels of free 3-nitrotyrosine are not elevated in the majority of patients with amyotrophic lateral sclerosis or Alzheimer's disease
2004
Intrastriatal dendrotoxin injection: Behavioral and neurochemical effects
1988
Inflammatory Neurodegeneration Mediated by Nitric Oxide, Glutamate, and Mitochondria
2003
Uniquantal Release through a Dynamic Fusion Pore Is a Candidate Mechanism of Hair Cell Exocytosis
2014 StandoutNobel
Alzheimer's Disease
2010 Standout
[39] Immunohistochemical methods to detect nitrotyrosine
1999
Modulation of calcium currents by a D1 dopaminergic protein kinase/phosphatase cascade in rat neostriatal neurons
1995 StandoutNobel
Extracellular accumulation of glutamate in the hippocampus induced by ischemia is not calcium dependent — In vitro and in vivo evidence
1989
The role of nitric oxide in multiple sclerosis
2002
Biological selectivity and functional aspects of protein tyrosine nitration
2003
Relevance of protein nitration in brain injury: a key pathophysiological mechanism in neurodegenerative, autoimmune, or inflammatory CNS diseases and stroke
2003
Neuronal Cell Death
1998
Nitric oxide, mitochondria and neurological disease
1999
DNA strand breakage and activation of poly-ADP ribosyltransferase: A cytotoxic pathway triggered by peroxynitrite
1996
Repertoires of Autophagy in the Pathogenesis of Ocular Diseases
2015 Standout
Energetic and structural interactions between δ-dendrotoxin and a voltage-gated potassium channel 1 1Edited by G. von Heijne
2000 StandoutNobel
Survival pathways triggered by peroxynitrite in cells belonging to the monocyte/macrophage lineage
2005
Nitrogen dioxide and carbonate radical anion: two emerging radicals in biology
2002
Characterization of the Interaction of a Recombinant Soluble Neuroligin-1 with Neurexin-1β
2003 StandoutNobel
Peroxynitrite and Hydrogen Peroxide Induced Cell Death in the NSC34 Neuroblastoma × Spinal Cord Cell Line: Role of Poly(ADP‐Ribose) Polymerase
1998
[41] Examining apoptosis in cultured cells after exposure to nitric oxide and peroxynitrite
1999
Effects of Exogenous Nitric Oxide and Hyperoxia on Lung Fibroblast Viability and DNA Fragmentation
1999
Oxidative stress and nitration in neurodegeneration: Cause, effect, or association?
2003
Click Chemistry In Situ: Acetylcholinesterase as a Reaction Vessel for the Selective Assembly of a Femtomolar Inhibitor from an Array of Building Blocks
2002 StandoutNobel
Dopamine in Motivational Control: Rewarding, Aversive, and Alerting
2010 Standout
Activation of src tyrosine kinases by peroxynitrite
1999
Nitric oxide and peroxynitrite induce cellular death in bovine chromaffin cells: Evidence for a mixed necrotic and apoptotic mechanism with caspases activation
2006
Structural Bases of Desensitization in AMPA Receptor-Auxiliary Subunit Complexes
2017 StandoutNobel
A Controlled Trial of Riluzole in Amyotrophic Lateral Sclerosis
1994 Standout
Motoneuron Death Triggered by a Specific Pathway Downstream of Fas
2002
Peroxynitrite: biochemistry, pathophysiology and development of therapeutics
2007 Standout
Carbon monoxide protects PC12 cells from peroxynitrite-induced apoptotic death by preventing the depolarization of mitochondrial transmembrane potential
2006
The TRA-1A Sex Determination Protein of C. elegans Regulates Sexually Dimorphic Cell Deaths by Repressing the egl-1 Cell Death Activator Gene
1999 StandoutNobel
A Unique Microglia Type Associated with Restricting Development of Alzheimer’s Disease
2017 Standout
Alteration of cytosolic free calcium homeostasis by SIN‐1: high sensitivity of L‐type Ca2+ channels to extracellular oxidative/nitrosative stress in cerebellar granule cells
2005
Necroptosis Drives Motor Neuron Death in Models of Both Sporadic and Familial ALS
2014
Reactions of manganese porphyrins and manganese-superoxide dismutase with peroxynitrite
2002
Effect of nitration on protein tyrosine phosphatase and protein phosphatase activity in neuronal cell membranes of newborn piglets
2005
Peroxynitrite-Induced Tyrosine Nitration and Inhibition of Protein Kinase C
2001
Influence of acetylcholinesterase on embryonic spinal rat motoneurones growth in culture: a quantitative morphometric study
1998
Reactive Nitrogen Species and Tyrosine Nitration in the Respiratory Tract
1999
Peroxynitrite-Induced Nitrotyrosination of Proteins Is Blocked by Direct 5-Lipoxygenase Inhibitor Zileuton
2001
Invited Review: Physiological and pathophysiological responses to intermittent hypoxia
2001
Oxidative Damage and Tyrosine Nitration from Peroxynitrite
1996
Blockade of membrane transport and disassembly of the Golgi complex by expression of syntaxin 1A in neurosecretion-incompetent cells: prevention by rbSEC1
1999
Biomedical applications of copper ionophores
2020
Endothelial dysfunction in a rat model of endotoxic shock. Importance of the activation of poly (ADP-ribose) synthetase by peroxynitrite.
1997
Evidence for peroxynitrite as a signaling molecule in flow-dependent activation of c-Jun NH2-terminal kinase
1999
Site of fasciculin interaction with acetylcholinesterase
1994
A Novel Superoxide Dismutase-Based Trap for Peroxynitrite Used To Detect Entry of Peroxynitrite into Erythrocyte Ghosts
1999
Biological Tyrosine Nitration: A Pathophysiological Function of Nitric Oxide and Reactive Oxygen Species
1998
Surprising gene expression patterns within and between PDF-containing circadian neurons in Drosophila
2010 StandoutNobel
Pain regulation by non-neuronal cells and inflammation
2016 StandoutScience
β-Amyloid Stimulation of Microglia and Monocytes Results in TNFα-Dependent Expression of Inducible Nitric Oxide Synthase and Neuronal Apoptosis
2001
Misfolded CuZnSOD and amyotrophic lateral sclerosis
2003
Peroxynitrite mediates calcium‐dependent mitochondrial dysfunction and cell death via activation of calpains
2004
Molecular Cloning and Functional Expression of Glutamate Receptor Subunit Genes
1990 Science
Peroxynitrite induces Alzheimer‐like tau modifications and accumulation in rat brain and its underlying mechanisms
2006
Copper Homeostasis and Neurodegenerative Disorders (Alzheimer's, Prion, and Parkinson's Diseases and Amyotrophic Lateral Sclerosis)
2006 Standout
Cytokine-Mediated Apoptosis in Cardiac Myocytes
1999
Mice carrying a human GLUD2 gene recapitulate aspects of human transcriptome and metabolome development
2016 StandoutNobel
Inactivation of tyrosine hydroxylase by nitration following exposure to peroxynitrite and 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)
1998
Structural Determinants of Ion Flow Through Recombinant Glutamate Receptor Channels
1991 StandoutScienceNobel
Mitochondrial Manganese Superoxide Dismutase Prevents Neural Apoptosis and Reduces Ischemic Brain Injury: Suppression of Peroxynitrite Production, Lipid Peroxidation, and Mitochondrial Dysfunction
1998
Oxidative stress and nitration in neurodegeneration: Cause, effect, or association?
2003
Alternative splicing generates functionally distinct N-methyl-D-aspartate receptors.
1992 StandoutNobel
Neural Science
2000 StandoutNobel
Spermidine in health and disease
2018 StandoutScience
How neuroinflammation contributes to neurodegeneration
2016 StandoutScience
Chronic inhibition of superoxide dismutase produces apoptotic death of spinal neurons.
1994
Regulation of apoptosis by the circadian clock through NF-κB signaling
2011 StandoutNobel
Peroxynitrite Mediates Neurotoxicity of Amyloid β-Peptide1–42- and Lipopolysaccharide-Activated Microglia
2002
Copper induces cell death by targeting lipoylated TCA cycle proteins
2022 StandoutScience
The biology , function , and biomedical applications of exosomes
2020 StandoutScience
Caspase-1 is activated in neural cells and tissue with amyotrophic lateral sclerosis-associated mutations in copper-zinc superoxide dismutase
1998
Part I: Pathogenetic Role of Peroxynitrite in the Development of Diabetes and Diabetic Vascular Complications: Studies With FP15, A Novel Potent Peroxynitrite Decomposition Catalyst
2002
Differential Susceptibility to Neurotoxicity Mediated by Neurotrophins and Neuronal Nitric Oxide Synthase
1997
Nitric oxide, oxidants, and protein tyrosine nitration
2004
Ischemic Cell Death in Brain Neurons
1999 Standout
Peroxynitrite-derived carbonate and nitrogen dioxide radicals readily react with lipoic and dihydrolipoic acid
2005
Nitration and inactivation of manganese superoxide dismutase in chronic rejection of human renal allografts.
1996
GSK-3: tricks of the trade for a multi-tasking kinase
2003 Standout
Induction of α-Synuclein Aggregation by Intracellular Nitrative Insult
2001
Impaired Degradation of Mutant α-Synuclein by Chaperone-Mediated Autophagy
2004 StandoutScience
Role of calcium and superoxide dismutase in sensitizing mitochondria to peroxynitrite-induced permeability transition
2004
Staurosporine-Induced Apoptosis of Cultured Rat Hippocampal Neurons Involves Caspase-1-Like Proteases as Upstream Initiators and Increased Production of Superoxide as a Main Downstream Effector
1998
Stress-Activated Cap'n'collar Transcription Factors in Aging and Human Disease
2010
Nitric oxide prevents axonal degeneration by inducing HIF-1–dependent expression of erythropoietin
2011 StandoutNobel
Pertussis toxin pretreatment abolishes the inhibitory effect of riluzole and carbachol on d[3H]aspartate release from cultured cerebellar granule cells
1992
Peroxynitrite mediates neurotoxicity of amyloid beta-peptide1-42- and lipopolysaccharide-activated microglia.
2002
Living and dying with reactive species Focus on “Peroxynitrite induces apoptosis of HL-60 cells by activation of a caspase-3 family protease”
1998
Peroxynitrite modulates tyrosine phosphorylation and phosphoinositide signalling in human neuroblastoma SH-SY5Y cells: attenuated effects in human 1321N1 astrocytoma cells
1998
Molecular Diversity of Glutamate Receptors and Implications for Brain Function
1992 StandoutScience
The effects of protease inhibitor homologues from mamba snake venoms on autonomic neurotransmission
1985
Heteromeric NMDA Receptors: Molecular and Functional Distinction of Subtypes
1992 StandoutScienceNobel
Works of Luis Barbeito being referenced
Copper delivery to the CNS by CuATSM effectively treats motor neuron disease in SODG93A mice co-expressing the Copper-Chaperone-for-SOD
2016
Acidic Fibroblast Growth Factor Enhances Peroxynitrite-Induced Apoptosis in Primary Murine Fibroblasts
1996
Substance P and neurokinin A regulate by different mechanisms dopamine release from dendrites and nerve terminals of the nigrostriatal dopaminergic neurons
1988
IFNγ triggers a LIGHT-dependent selective death of motoneurons contributing to the non-cell-autonomous effects of mutant SOD1
2010
Liposome-delivered superoxide dismutase prevents nitric oxide–dependent motor neuron death induced by trophic factor withdrawal
2000
Increased glutathione biosynthesis by Nrf2 activation in astrocytes prevents p75NTR‐dependent motor neuron apoptosis
2006
Peroxynitrite transforms nerve growth factor into an apoptotic factor for motor neurons
2006
Superoxide dismutase and the death of motoneurons in ALS
2001
CCS knockout mice establish an alternative source of copper for SOD in ALS
2002
Glutamate Receptors of a Quisqualate‐Kainate Subtype are Involved in the Presynaptic Regulation of Dopamine Release in the Cat Caudate Nucleus in vivo
1990
Riluzole inhibits the release of glutamate in the caudate nucleus of the cat in vivo
1992
Behavioral and neurochemical effects of intraperitoneally injected dendrotoxin
1988
Transcriptional profile of primary astrocytes expressing ALS‐linked mutant SOD1
2008
Role of excitatory amino acids in the direct and indirect presynaptic regulation of dopamine release from nerve terminals of nigrostriatal dopaminergic neurons
1991
Astrocytic production of nerve growth factor in motor neuron apoptosis: implications for amyotrophic lateral sclerosis
2004
Mitochondrial Superoxide Production and Nuclear Factor Erythroid 2-Related Factor 2 Activation in p75 Neurotrophin Receptor-Induced Motor Neuron Apoptosis
2007
Mitochondrial Dysfunction in SOD1G93A-Bearing Astrocytes Promotes Motor Neuron Degeneration: Prevention by Mitochondrial-Targeted Antioxidants
2008
Nerve Growth Factor Protects PC12 Cells Against Peroxynitrite‐Induced Apoptosis via a Mechanism Dependent on Phosphatidylinositol 3‐Kinase
1997
Induction of motor neuron apoptosis by free 3‐nitro‐l ‐tyrosine
2004
Astrocyte activation by fibroblast growth factor‐1 and motor neuron apoptosis: implications for amyotrophic lateral sclerosis
2005
Fasciculin, a powerful anticholinesterase polypeptide from Dendroaspis angusticeps venom
1983
A role for astrocytes in motor neuron loss in amyotrophic lateral sclerosis
2004
Chapter 19 Role of endogenous nitric oxide and peroxynitrite formation in the survival and death of motor neurons in culture
1998
The Molecular Bases of Alzheimer's Disease and Other Neurodegenerative Disorders
2001
Effect of DSP-4, a Noradrenergic Neurotoxin, on Sleep and Wakefulness and Sensitivity to Drugs Acting on Adrenergic Receptors in the Rat
1988
Peroxynitrite‐Induced Cytotoxicity in PC12 Cells: Evidence for an Apoptotic Mechanism Differentially Modulated by Neurotrophic Factors
1995
Fibroblast Growth Factor-1 Induces Heme Oxygenase-1 via Nuclear FactorErythroid 2-related Factor 2 (Nrf2) in Spinal Cord Astrocytes
2005
Nitric Oxide-Mediated Oxidative Damage and the Progressive Demise of Motor Neurons in ALS
2012
Peroxynitrite triggers a phenotypic transformation in spinal cord astrocytes that induces motor neuron apoptosis
2001
Protective effect of riluzole on excitatory amino acid-mediated neurotoxicity in motoneuron-enriched cultures
1995
Astroglial Nitration after Postnatal Excitotoxic Damage: Correlation with Nitric Oxide Sources, Cytoskeletal, Apoptotic and Antioxidant Proteins
2005
Nitric Oxide-Dependent Production of cGMP Supports the Survival of Rat Embryonic Motor Neurons Cultured with Brain-Derived Neurotrophic Factor
1998
Nitric Oxide and Superoxide Contribute to Motor Neuron Apoptosis Induced by Trophic Factor Deprivation
1998
Astrocytic nitric oxide triggers tau hyperphosphorylation in hippocampal neurons.
2005
Superoxide dismutase and the death of motoneurons in ALS
2001
Phenotypically aberrant astrocytes that promote motoneuron damage in a model of inherited amyotrophic lateral sclerosis
2011
Stimulation of nerve growth factor expression in astrocytes by peroxynitrite.
2005
FGF-1 induces ATP release from spinal astrocytes in culture and opens pannexin and connexin hemichannels
2010
In Vivo Release of Endogenous Amino Acids from the Rat Striatum: Further Evidence for a Role of Glutamate and Aspartate in Corticostriatal Neurotransmission
1986