Citation Impact
Citing Papers
Histone demethylase KDM6A directly senses oxygen to control chromatin and cell fate
2019 StandoutScienceNobel
Genomic Variation in Seven Khoe-San Groups Reveals Adaptation and Complex African History
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Protein characterization of Saccharomyces cerevisiae RNA polymerase II after in vivo cross-linking
2007 StandoutNobel
Structural Basis of Transcription: Backtracked RNA Polymerase II at 3.4 Angstrom Resolution
2009 StandoutScienceNobel
Innate Immune Activation Through Nalp3 Inflammasome Sensing of Asbestos and Silica
2008 StandoutScience
Lysine Acetylation Targets Protein Complexes and Co-Regulates Major Cellular Functions
2009 StandoutScience
Polycomb Group Protein Enhancer of Zeste 2 Is an Oncogene That Promotes the Neoplastic Transformation of a Benign Prostatic Epithelial Cell Line
2009
Clonal Integration of a Polyomavirus in Human Merkel Cell Carcinoma
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Inhibition of early steps in the lentiviral replication cycle by cathelicidin host defense peptides
2005
A RASSF1A-HIF1α loop drives Warburg effect in cancer and pulmonary hypertension
2019 StandoutNobel
Two transactivation mechanisms cooperate for the bulk of HIF‐1‐responsive gene expression
2005
Hallmarks of Cancer: The Next Generation
2011 Standout
Tuning the Transcriptional Response to Hypoxia by Inhibiting Hypoxia-inducible Factor (HIF) Prolyl and Asparaginyl Hydroxylases
2016 StandoutNobel
The pRb-related protein p130 is regulated by phosphorylation-dependent proteolysis via the protein–ubiquitin ligase SCFSkp2
2002
Inhibition of P-TEFb (CDK9/Cyclin T) Kinase and RNA Polymerase II Transcription by the Coordinated Actions of HEXIM1 and 7SK snRNA
2003
Intramolecular Control of Protein Stability, Subnuclear Compartmentalization, and Coactivator Function of Peroxisome Proliferator-activated Receptor γ Coactivator 1α
2007
Inflammation and cancer
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CD34+ Cord Blood Cell-Transplanted Rag2−/− γc−/− Mice as a Model for Epstein-Barr Virus Infection
2008
Vedolizumab as Induction and Maintenance Therapy for Ulcerative Colitis
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The retinoblastoma gene family in differentiation and development
1999
MYC on the Path to Cancer
2012 Standout
Comprehensive evaluation of the role of EZH2 in the growth, invasion, and aggression of a panel of prostate cancer cell lines
2010
Influence of Metabolism on Epigenetics and Disease
2013 StandoutNobel
Epigenetic Silencing of the RASSF1A Tumor Suppressor Gene through HOXB3-Mediated Induction of DNMT3B Expression
2009
RNAi screen identifies Brd4 as a therapeutic target in acute myeloid leukaemia
2011 StandoutNature
The SIN3A histone deacetylase complex is required for a complete transcriptional response to hypoxia
2017 StandoutNobel
The Failing Heart — An Engine Out of Fuel
2007 Standout
Role of the SCFSkp2 Ubiquitin Ligase in the Degradation of p21Cip1 in S Phase
2003 StandoutNobel
ATP-dependent chromatin remodelers in ageing and age-related disorders
2020
UTX mediates demethylation of H3K27me3 at muscle-specific genes during myogenesis
2010
The retinoblastoma family: twins or distant cousins?
2002
The relationship between angiogenesis and the immune response in carcinogenesis and the progression of malignant disease
2000
Hallmarks of aging: An expanding universe
2023 Standout
Antimicrobial Peptides as Mediators of Epithelial Host Defense
1999
Calcineurin Promotes Hypoxia-inducible Factor 1α Expression by Dephosphorylating RACK1 and Blocking RACK1 Dimerization
2007 StandoutNobel
Cancer Epigenetics: From Mechanism to Therapy
2012 Standout
Recruitment of P-TEFb for Stimulation of Transcriptional Elongation by the Bromodomain Protein Brd4
2005
Interaction between HIV-1 Tat and pRb2/p130: a possible mechanism in the pathogenesis of AIDS-related neoplasms
2003
Histone Deacetylase Inhibitors Repress the Transactivation Potential of Hypoxia-inducible Factors Independently of Direct Acetylation of HIF-α
2006
Histone deacetylases, transcriptional control, and cancer
2000
The Positive Transcription Elongation Factor b Is an Essential Cofactor for the Activation of Transcription by Myocyte Enhancer Factor 2
2008
Modulation of Cell Cycle Components by Epigenetic and Genetic Events
2005
Cardiac Myocyte Cell Cycle Control in Development, Disease, and Regeneration
2007
The Bromodomain Protein Brd4 Is a Positive Regulatory Component of P-TEFb and Stimulates RNA Polymerase II-Dependent Transcription
2005
Cellular and molecular parameters of mesothelioma
2006
Super-Enhancers in the Control of Cell Identity and Disease
2013 Standout
RB and cell cycle progression
2006 Standout
Sizing up the heart: development redux in disease
2003
The Histone Chaperone Spt6 Is Required for Activation-induced Cytidine Deaminase Target Determination through H3K4me3 Regulation
2012 StandoutNobel
Role of cell‐cycle regulators in lung cancer
2005
Genetic Alterations of the Retinoblastoma-Related Gene RB2/p130 Identify Different Pathogenetic Mechanisms in and among Burkitt's Lymphoma Subtypes
2000
A myocardial lineage derives from Tbx18 epicardial cells
2008 StandoutNature
A Chromatin Landmark and Transcription Initiation at Most Promoters in Human Cells
2007 Standout
Are RB proteins a potential substrate of Pin1 in the regulation of the cell cycle?
2005
Cyclin D as a therapeutic target in cancer
2011
Chronic immune activation and inflammation in the pathogenesis of aids and cancer
2002
Expression of RB2/p130 tumor-suppressor gene in AIDS-related non-Hodgkin's lymphomas: Implications for disease pathogenesis
2002
Common genetic variants at the 11q13.3 renal cancer susceptibility locus influence binding of HIF to an enhancer of cyclin D1 expression
2012 StandoutNobel
Suppression of inflammation by a synthetic histone mimic
2010 StandoutNatureNobel
Inflammation and cancer: back to Virchow?
2001 Standout
RNA-based affinity purification reveals 7SK RNPs with distinct composition and regulation
2007
Genomic and Epigenomic Landscapes of Adult De Novo Acute Myeloid Leukemia
2013 Standout
Structural Studies of Porcine Myeloid Antibacterial Peptide PMAP-23 and Its Analogues in DPC Micelles by NMR Spectroscopy
2002
Mechanism of Action of the Antimicrobial Peptide Buforin II: Buforin II Kills Microorganisms by Penetrating the Cell Membrane and Inhibiting Cellular Functions
1998
Structure and Biology of Cathelicidins
2002
The Noncoding RNA Revolution—Trashing Old Rules to Forge New Ones
2014 Standout
AKT/PKB Signaling: Navigating the Network
2017 Standout
Elongation by RNA polymerase II: the short and long of it
2004
Exploring complex networks
2001 StandoutNature
Regulation of cardiac hypertrophy by intracellular signalling pathways
2006 Standout
In vitro and in vivo antimicrobial activity of two α-helical cathelicidin peptides and of their synthetic analogs
2003
Antimicrobial peptides of multicellular organisms
2002 StandoutNature
The Transcription Factor Mef2 Links the Drosophila Core Clock to Fas2, Neuronal Morphology, and Circadian Behavior
2013 StandoutNobel
FIH-1: a novel protein that interacts with HIF-1α and VHL to mediate repression of HIF-1 transcriptional activity
2001 StandoutNobel
Vedolizumab as Induction and Maintenance Therapy for Crohn's Disease
2013 Standout
Impact of Preexisting and Induced Humoral and Cellular Immune Responses in an Adenovirus-Based Gene Therapy Phase I Clinical Trial for Localized Mesothelioma
1998
The Polycomb complex PRC2 and its mark in life
2011 StandoutNature
PGC-1 coactivators: inducible regulators of energy metabolism in health and disease
2006
The Cathelicidin Family of Antimicrobial Peptide Precursors: A Component of the Oxygen‐Independent Defense Mechanisms of Neutrophilsa
1997
Population‐based study of antibody to the human polyomaviruses BKV and JCV and the simian polyomavirus SV40
2003
A decade of discoveries in cardiac biology
2004
Synergistic role of E1A-Binding proteins and tissue-specific transcription factors in differentiation
1997
The Extending Network of FOXO Transcriptional Target Genes
2010
Activity of Protegrins against Yeast-Phase Candida albicans
1998
Reactive oxygen species play no role in the candidacidal activity of the salivary antimicrobial peptide histatin 5
2004
RNA–protein analysis using a conditional CRISPR nuclease
2013 StandoutNobel
Accumulation of the FACT complex, as well as histone H3.3, serves as a target marker for somatic hypermutation
2013 StandoutNobel
Peptide Antimicrobial Agents
2006 Standout
The retinoblastoma gene family: its role in cancer onset and progression
2000
Cathelicidins, multifunctional peptides of the innate immunity
2003
Molecular Interaction Map of the Mammalian Cell Cycle Control and DNA Repair Systems
1999 Nobel
Current and Prospective Protein Biomarkers of Lung Cancer
2017
Retinoblastoma protein family in cell cycle and cancer: A review
1996
Pleistocene North African genomes link Near Eastern and sub-Saharan African human populations
2018 StandoutScienceNobel
Transient Regenerative Potential of the Neonatal Mouse Heart
2011 StandoutScience
Priming of protective T cell responses against virus-induced tumors in mice with human immune system components
2009 StandoutNobel
Rapid Infection of Oral Mucosal-Associated Lymphoid Tissue with Simian Immunodeficiency Virus
1999 StandoutScienceNobel
Acetylation of Conserved Lysines in the Catalytic Core of Cyclin-Dependent Kinase 9 Inhibits Kinase Activity and Regulates Transcription
2008
MicroRNA-29a and microRNA-142-3p are regulators of myeloid differentiation and acute myeloid leukemia
2012
Myc Enforces Overexpression ofEZH2in Early Prostatic Neoplasia via Transcriptional and Post-transcriptional Mechanisms
2011
Identification of Transcription Complexes that Contain the Double Bromodomain Protein Brd2 and Chromatin Remodeling Machines
2006
Human DNA Repair Genes
2001 StandoutScienceNobel
Molecular Origin of Blood‐Based Infrared Spectroscopic Fingerprints**
2021 StandoutNobel
Phylogenetic Perspectives in Innate Immunity
1999 StandoutScienceNobel
Is There a Role for SV40 in Human Cancer?
2006
Mitochondrial activation chemicals synergize with surface receptor PD-1 blockade for T cell-dependent antitumor activity
2017 StandoutNobel
Cyclin-Dependent Kinase-9
2004
RBP1 Recruits Both Histone Deacetylase-Dependent and -Independent Repression Activities to Retinoblastoma Family Proteins
1999 StandoutNobel
Works of Luigi Bagella being referenced
A Unique Domain of pRb2/p130 Acts as an Inhibitor of Cdk2 Kinase Activity
1997
Importance of Ezh2 polycomb protein in tumorigenesis process interfering with the pathway of growth suppressive key elements
2007
cDNA sequences of three sheep myeloid cathelicidins
1995
Histone Deacetylase Inhibitors in the Treatment of Hematological Malignancies and Solid Tumors
2010
Activation of MyoD-dependent transcription by cdk9/cyclin T2
2002
MyoD recruits the cdk9/cyclin T2 complex on Myogenic‐genes regulatory regions
2005
Biological Characterization of Two Novel Cathelicidin-derived Peptides and Identification of Structural Requirements for Their Antimicrobial and Cell Lytic Activities
1996
A small molecule based on the pRb2/p130 spacer domain leads to inhibition of cdk2 activity, cell cycle arrest and tumor growth reduction in vivo
2006
Physical interaction between pRb and cdk9/cyclinT2 complex
2002
Physical interaction between CDK9 and B-Myb results in suppression of B-Myb gene autoregulation
2000
From G0 to S phase: A view of the roles played by the retinoblastoma (Rb) family members in the Rb‐E2F pathway
2007
Ezh2 reduces the ability of HDAC1-dependent pRb2/p130 transcriptional repression of cyclin A
2004
The retinoblastoma gene family pRb/p105, p107, pRb2/p130 and simian virus-40 large T-antigen in human mesotheliomas
1997
CDK9/CYCLIN T1 expression during normal lymphoid differentiation and malignant transformation
2004
Activation and function of cyclin T–Cdk9 (positive transcription elongation factor-b) in cardiac muscle-cell hypertrophy
2002
The BRG1 ATPase of chromatin remodeling complexes is involved in modulation of mesenchymal stem cell senescence through RB–P53 pathways
2010
Deacetylase recruitment by the C/H3 domain of the acetyltransferase p300
2004
The COOH-terminal region of pRb2/p130 binds to histone deacetylase 1 (HDAC1), enhancing transcriptional repression of the E2F-dependent cyclin A promoter.
1998
CTCF and BORIS Regulate Rb2/p130 Gene Transcription: A Novel Mechanism and a New Paradigm for Understanding the Biology of Lung Cancer
2011
Molecular cloning, expression, and developmental characterization of the murine retinoblastoma-related gene Rb2/p130.
1995
Independent prognostic role of p16 expression in lung cancer
1999