Citation Impact
Citing Papers
Activation of the BCL2 Promoter in Response to Hedgehog/GLI Signal Transduction Is Predominantly Mediated by GLI2
2004
Vascular Klotho Deficiency Potentiates the Development of Human Artery Calcification and Mediates Resistance to Fibroblast Growth Factor 23
2012 Standout
Loss of the Forkhead Transcription Factor FoxM1 Causes Centrosome Amplification and Mitotic Catastrophe
2005
Identification of a Chemical Inhibitor of the Oncogenic Transcription Factor Forkhead Box M1
2006
Epidermal Growth Factor Receptor Signaling Synergizes with Hedgehog/GLI in Oncogenic Transformation via Activation of the MEK/ERK/JUN Pathway
2009
Increased Levels of the FoxM1 Transcription Factor Accelerate Development and Progression of Prostate Carcinomas in both TRAMP and LADY Transgenic Mice
2006
WNT16B Is a New Marker of Cellular Senescence That Regulates p53 Activity and the Phosphoinositide 3-Kinase/AKT Pathway
2009
Expression profiling of microdissected cell populations selected from basal cells in normal epidermis and basal cell carcinoma
2008
1 Developmental roles and clinical significance of Hedgehog signaling
2003
Phosphoglycerate dehydrogenase induces glioma cells proliferation and invasion by stabilizing forkhead box M1
2012
Skin cancer in solid organ transplant recipients: Advances in therapy and management
2011
Snail induction is an early response to Gli1 that determines the efficiency of epithelial transformation
2005
Ornithine decarboxylase is a target for chemoprevention of basal and squamous cell carcinomas in Ptch1+/– mice
2004
Activation of Expression of Hedgehog Target Genes in Basal Cell Carcinomas
2001
Basal cell carcinomas: attack of the hedgehog
2008 Standout
Efficacy and Safety of Vismodegib in Advanced Basal-Cell Carcinoma
2012 Standout
Comparative gene expression profile analysis of GLI and c-MYC in an epithelial model of malignant transformation.
2002
Expression of a sonic hedgehog signal transducer, hedgehog-interacting protein, by human basal cell carcinoma
2002
FOXE1, A New Transcriptional Target of GLI2 Is Expressed in Human Epidermis and Basal Cell Carcinoma
2004
Sonic hedgehog signaling in basal cell carcinomas
2004
Patched1 Functions as a Gatekeeper by Promoting Cell Cycle Progression
2006
Hedgehog signalling in cancer formation and maintenance
2003 Standout
Atopic Dermatitis
2008 Standout
Hedgehog: functions and mechanisms
2008 Standout
Phorbol esters inhibit the Hedgehog signalling pathway downstream of Suppressor of Fused, but upstream of Gli
2007
The mechanisms of Hedgehog signalling and its roles in development and disease
2013 Standout
Expression of human β‐defensins‐1 and ‐2 peptides in unresolved chronic periodontitis
2004
Somatic mutations in thePTCH,SMOH,SUFUHandTP53genes in sporadic basal cell carcinomas
2005
Analysis of skin cancer risk factors in immunosuppressed renal transplant patients shows high levels of UV-specific tandem CC to TT mutations of the p53 gene
2006
Persistent kallikrein 5 activation induces atopic dermatitis-like skin architecture independent of PAR2 activity
2017 StandoutNobel
Bowel Disorders
2016 Standout
WNTs in the Neonatal Mouse Uterus: Potential Regulation of Endometrial Gland Development
2010
Human papillomavirus oncoproteins: pathways to transformation
2010 Standout
Molecular mechanisms of epithelial–mesenchymal transition
2014 Standout
Molecular subclasses of high-grade glioma predict prognosis, delineate a pattern of disease progression, and resemble stages in neurogenesis
2006 Standout
Atopic dermatitis
2015 Standout
Corneodesmosomal Cadherins Are Preferential Targets of Stratum Corneum Trypsin- and Chymotrypsin-like Hyperactivity in Netherton Syndrome
2006
Malignant astrocytic glioma: genetics, biology, and paths to treatment
2007 Standout
Gestational trophoblastic disease
2010 Standout
Chemoresistance in Prostate Cancer Cells Is Regulated by miRNAs and Hedgehog Pathway
2012
Combination of a rapamycin analog (CCI‐779) and interferon‐γ is more effective than single agents in treating a mouse model of tuberous sclerosis complex
2006
Heat Shock Protein A12B Protects Vascular Endothelial Cells Against Sepsis-Induced Acute Lung Injury in Mice
2017 Standout
Foxm1b transcription factor is essential for development of hepatocellular carcinomas and is negatively regulated by the p19ARF tumor suppressor
2004
Cancer genes and the pathways they control
2004 Standout
The Endocannabinoid System as an Emerging Target of Pharmacotherapy
2006 Standout
Will the History and Physical Examination Help Establish That Irritable Bowel Syndrome Is Causing This Patient's Lower Gastrointestinal Tract Symptoms?
2008
The Sonic Hedgehog–Patched–Gli Pathway in Human Development and Disease
2000
Skin cancer in solid organ transplant recipients: Advances in therapy and management
2011
Peeling off the genetics of atopic dermatitis–like congenital disorders
2014
Molecular Mechanisms Regulating Hair Follicle Development
2002
WNT Signals Are Required for the Initiation of Hair Follicle Development
2002 Standout
Neural contractions in colonic strips from patients with diverticular disease: role of endocannabinoids and substance P
2006
The emerging roles of forkhead box (Fox) proteins in cancer
2007
Propionibacterium acnes and lipopolysaccharide induce the expression of antimicrobial peptides and proinflammatory cytokines/chemokines in human sebocytes
2006
Carcinogenesis of basal cell carcinomas: genetics and molecular mechanisms
2002
Inhibition of the Hedgehog Pathway in Advanced Basal-Cell Carcinoma
2009 Standout
Acne vulgaris
2011 Standout
Unraveling the therapeutic potential of the Hedgehog pathway in cancer
2013 Standout
Molecular requirements for epithelial–mesenchymal transition during tumor progression
2005 Standout
Tuberous sclerosis
2008 Standout
Gli and hedgehog in cancer: tumours, embryos and stem cells
2002
A Transcriptome Database for Astrocytes, Neurons, and Oligodendrocytes: A New Resource for Understanding Brain Development and Function
2008 Standout
Hedgehog signaling in animal development: paradigms and principles
2001 Standout
Induction of gene encoding FABP4 in Pten‐null keratinocytes
2009 StandoutNobel
Papillomavirus E6 proteins
2008
Macrophages as regulators of tumour immunity and immunotherapy
2019 Standout
Human chorionic gonadotropin tests
2009
Periodontitis: a polymicrobial disruption of host homeostasis
2010 Standout
KRAS, Hedgehog, Wnt and the twisted developmental biology of pancreatic ductal adenocarcinoma
2010
Glypican-1 identifies cancer exosomes and detects early pancreatic cancer
2015 StandoutNature
Hedgehog–Gli signaling in brain tumors: stem cells and paradevelopmental programs in cancer
2003
The role of senescent cells in ageing
2014 StandoutNature
Idiopathic pulmonary fibrosis
2011 Standout
Aberrant FoxM1B expression increases matrix metalloproteinase-2 transcription and enhances the invasion of glioma cells
2007
Transcriptional Regulation of bcl-2 Mediated by the Sonic Hedgehog Signaling Pathway through gli-1
2004
New developments in our understanding of acne pathogenesis and treatment
2009
Antimicrobial Peptides: An Essential Component of the Skin Defensive Barrier
2006
Characterization of Gene Expression Profiles Associated with Glioma Progression Using Oligonucleotide-Based Microarray Analysis and Real-Time Reverse Transcription-Polymerase Chain Reaction
2003
The prognostic landscape of genes and infiltrating immune cells across human cancers
2015 Standout
Evidence for an Expansion-Based Temporal Shh Gradient in Specifying Vertebrate Digit Identities
2004 Standout
The primary cilium: a signalling centre during vertebrate development
2010 Standout
Molecular Regulation of Vascular Smooth Muscle Cell Differentiation in Development and Disease
2004 Standout
Differential epithelial expression of SHH and FOXF1 in usual and nonspecific interstitial pneumonia
2006
The Myofibroblast
2007 Standout
A heterozygous null mutation combined with the G1258A polymorphism ofSPINK5causes impaired LEKTI function and abnormal expression of skin barrier proteins
2009
The human skin microbiome
2018 Standout
Serine Synthesis Helps Hypoxic Cancer Stem Cells Regulate Redox
2016 StandoutNobel
The TAM family: phosphatidylserine-sensing receptor tyrosine kinases gone awry in cancer
2014
EDC-2: The Endocrine Society's Second Scientific Statement on Endocrine-Disrupting Chemicals
2015 Standout
Aging, Cellular Senescence, and Cancer
2012 Standout
Gene Regulatory Networks and the Evolution of Animal Body Plans
2006 StandoutScience
Selective Modulation of Hedgehog/GLI Target Gene Expression by Epidermal Growth Factor Signaling in Human Keratinocytes
2006
Melanomas require HEDGEHOG-GLI signaling regulated by interactions between GLI1 and the RAS-MEK/AKT pathways
2007
Traditional Chinese medicine as a cancer treatment: Modern perspectives of ancient but advanced science
2019 Standout
Chk2 Mediates Stabilization of the FoxM1 Transcription Factor To Stimulate Expression of DNA Repair Genes
2006
Practice Guidelines for the Diagnosis and Management of Aspergillosis: 2016 Update by the Infectious Diseases Society of America
2016 Standout
Forkhead Transcription Factor FoxM1 Regulates Mitotic Entry and Prevents Spindle Defects in Cerebellar Granule Neuron Precursors
2007
Hepatocellular Carcinoma: Epidemiology and Molecular Carcinogenesis
2007 Standout
Silver Nanoparticles: Synthesis, Characterization, Properties, Applications, and Therapeutic Approaches
2016 Standout
Indian hedgehog and β-catenin signaling: Role in the sebaceous lineage of normal and neoplastic mammalian epidermis
2003
Protein Kinase C-δ and Mitogen-Activated Protein/Extracellular Signal–Regulated Kinase-1 Control GLI Activation in Hedgehog Signaling
2006
New and unexpected: forkhead meets ARF
2004
Vascular Smooth Muscle Cells in Atherosclerosis
2016 Standout
FoxM1B Is Overexpressed in Human Glioblastomas and Critically Regulates the Tumorigenicity of Glioma Cells
2006
The Forkhead Box M1 Transcription Factor Contributes to the Development and Growth of Mouse Colorectal Cancer
2007
Normal development is an integral part of tumorigenesis in T cell-specific PTEN-deficient mice
2008 StandoutNobel
UV Radiation and the Skin
2013 Standout
The Forkhead Box m1b transcription factor is essential for hepatocyte DNA replication and mitosis during mouse liver regeneration
2002
The Forkhead Box m1 Transcription Factor Stimulates the Proliferation of Tumor Cells during Development of Lung Cancer
2006
Works of Lucy Ghali being referenced
Gli1 Protein is Expressed in Basal Cell Carcinomas, Outer Root Sheath Keratinocytes and a Subpopulation of Mesenchymal Cells in Normal Human Skin
1999
Loss of protein kinase Calpha expression may enhance the tumorigenic potential of Gli1 in basal cell carcinoma.
2003
Safety and Efficacy of 5% Imiquimod Cream for the Treatment of Skin Dysplasia in High-Risk Renal Transplant Recipients
2005
GLI1 repression of ERK activity correlates with colony formation and impaired migration in human epidermal keratinocytes
2008
FOXM1 is a downstream target of Gli1 in basal cell carcinomas.
2002
Role for WNT16B in human epidermal keratinocyte proliferation and differentiation
2007
GLI1 Confers Profound Phenotypic Changes upon LNCaP Prostate Cancer Cells That Include the Acquisition of a Hormone Independent State
2011
LEKTI demonstrable by immunohistochemistry of the skin: a potential diagnostic skin test for Netherton syndrome
2004
Role of HPV E6 proteins in preventing UVB-induced release of pro-apoptotic factors from the mitochondria
2006
Axl Promotes Cutaneous Squamous Cell Carcinoma Survival through Negative Regulation of Pro-Apoptotic Bcl-2 Family Members
2010
hCGβ expression by cervical squamous carcinoma –in vivo histological association with tumour invasion and apoptosis
2008
Phytochemical Modulation of Apoptosis and Autophagy: Strategies to Overcome Chemoresistance in Leukemic Stem Cells in the Bone Marrow Microenvironment
2017
The E7 Protein of Cutaneous Human Papillomavirus Type 8 Causes Invasion of Human Keratinocytes into the Dermis in Organotypic Cultures of Skin
2005
Human β Defensin-1 and -2 Expression in Human Pilosebaceous Units: Upregulation in Acne Vulgaris Lesions
2001
Smooth muscle cholinergic denervation hypersensitivity in diverticular disease
2003