Citation Impact
Citing Papers
Targeting of HIF-α to the von Hippel-Lindau Ubiquitylation Complex by O 2 -Regulated Prolyl Hydroxylation
2001 StandoutScienceNobel
Triggering a Cell Shape Change by Exploiting Preexisting Actomyosin Contractions
2012 StandoutScienceNobel
Directed evolution of cytochrome c for carbon–silicon bond formation: Bringing silicon to life
2016 StandoutScienceNobel
Parkinson-like syndrome induced by continuous MPTP infusion: Convergent roles of the ubiquitin-proteasome system and α-synuclein
2005 StandoutNobel
Bioorthogonal Chemistry: Fishing for Selectivity in a Sea of Functionality
2009 StandoutNobel
C. elegans EGL-9 and Mammalian Homologs Define a Family of Dioxygenases that Regulate HIF by Prolyl Hydroxylation
2001 StandoutNobel
Dysfunction of mitochondrial complex I and the proteasome: interactions between two biochemical deficits in a cellular model of Parkinson's disease
2003
Drug discovery approaches targeting the PI3K/Akt pathway in cancer
2008
The biology and management of non-small cell lung cancer
2018 StandoutNature
Epidermal growth factor receptor mutations in lung cancer
2007 Standout
CH Bond Functionalization: Emerging Synthetic Tools for Natural Products and Pharmaceuticals
2012 Standout
Proteasome-Mediated Processing of Nrf1 Is Essential for Coordinate Induction of All Proteasome Subunits and p97
2014
Proteasome Inhibitors: Complex Tools for a Complex Enzyme
2002
The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis
1999 StandoutNatureNobel
Lack of Proteasome Active Site Allostery as Revealed by Subunit-Specific Inhibitors
2001
Proteasome- and p53-dependent Masking of Signal Transducer and Activator of Transcription (STAT) Factors
1997 StandoutNobel
Cytosolic Degradation of T-cell Receptor α Chains by the Proteasome
1997
The IKK NF-κB system: a treasure trove for drug development
2004
HIF-1, O2, and the 3 PHDs
2001 StandoutNobel
Covalent protein modification: the current landscape of residue-specific electrophiles
2014
Lactacystin and clasto-Lactacystin β-Lactone Modify Multiple Proteasome β-Subunits and Inhibit Intracellular Protein Degradation and Major Histocompatibility Complex Class I Antigen Presentation
1997
A Genetically Encoded Boronate‐Containing Amino Acid
2008
Enzymatic assembly of carbon–carbon bonds via iron-catalysed sp3 C–H functionalization
2018 StandoutNatureNobel
The Proteasome: Paradigm of a Self-Compartmentalizing Protease
1998
Protein‐Reactive Natural Products
2005
Nuclear factor-κB in cancer development and progression
2006 StandoutNature
A proteolytic system that compensates for loss of proteasome function
1998 Nature
Glutathiolation of the Proteasome Is Enhanced by Proteolytic Inhibitors
2001
Hypoxia-inducible Factor 1α (HIF-1α) Protein Is Rapidly Degraded by the Ubiquitin-Proteasome System under Normoxic Conditions
1997 Standout
HIF-1 Regulates Cytochrome Oxidase Subunits to Optimize Efficiency of Respiration in Hypoxic Cells
2007 StandoutNobel
Proteasome: from structure to function
1996
Substrate binding and sequence preference of the proteasome revealed by active-site-directed affinity probes
1998
β2-Adrenergic Receptor Down-regulation
1999
A Cell Cycle Timer for Asymmetric Spindle Positioning
2009
Extended peptide-based inhibitors efficiently target the proteasome and reveal overlapping specificities of the catalytic β-subunits
2001
Asymmetric Carboselenenylation Reaction of Alkenes with Aromatic Compounds
2005
Chapter 11 Proteinase families and their inhibitors
2001
Protein Sequence Editing of SKN-1A/Nrf1 by Peptide:N-Glycanase Controls Proteasome Gene Expression
2019 StandoutNobel
Proteasome inhibitors: fromin vitro uses to clinical trials
2000
Lactacystin, a Specific Inhibitor of the Proteasome, Inhibits Human Platelet Lysosomal Cathepsin A-like Enzyme
1997 StandoutNobel
Towards subunit-specific proteasome inhibitors: synthesis and evaluation of peptide α', β'-epoxyketones
1999
Modeling neurodevelopmental disorder-associated humanAGO1mutations inCaenorhabditis elegansArgonautealg-1
2024 StandoutNobel
Peptidic degron in EID1 is recognized by an SCF E3 ligase complex containing the orphan F-box protein FBXO21
2015 StandoutNobel
β-Arrestin 1 and 2 differentially regulate heptahelical receptor signaling and trafficking
2001 StandoutNobel
Design of optically active selenium reagents having a chiral tertiary amino group and their application to asymmetric inter- and intramolecular oxyselenenylations
1997
SuFEx Click Chemistry Enabled Late-Stage Drug Functionalization
2018 StandoutNobel
The mouse and human genes encoding the recognition component of the N-end rule pathway
1998 StandoutNobel
Asymmetric electrophilic methoxyselenenylations and cyclizations with 3-camphorseleno derivatives
1999
A mutation of Ikbkg causes immune deficiency without impairing degradation of IκBα
2010 StandoutNobel
Asymmetric Intermolecular Carbenoid C−H Insertions Catalyzed by Rhodium(II) (S)-N-(p-Dodecylphenyl)sulfonylprolinate
1997
Challenges and Opportunities for the Application of Boron Clusters in Drug Design
2016
Fluoroselenenylation of Acetylenes with Xenon Difluoride–Diorganyl Diselenides; Synthesis and Structure Elucidation of Functionalized Vicinal (E)‐Fluoro(organylseleno)olefins
1996
Photoexpulsion of Surface-Grafted Ruthenium Complexes and Subsequent Release of Cytotoxic Cargos to Cancer Cells from Mesoporous Silica Nanoparticles
2013 StandoutNobel
The 26S Proteasome: A Molecular Machine Designed for Controlled Proteolysis
1999 Standout
Heat shock proteins: Biological functions, pathological roles, and therapeutic opportunities
2022
Strategies for the Total Synthesis of C2−C11 Cyclized Cembranoids
2008
Practical Synthesis of (R,R)- and (S,S)-Bis[2,6-bis(1-ethoxyethyl)phenyl] Diselenide
1996
Origin of Stereoselectivities in Asymmetric Alkoxyselenenylations
1999
Hypoxia-inducible factor 1α protein expression is controlled by oxygen-regulated ubiquitination that is disrupted by deletions and missense mutations
2000 StandoutNobel
Physiology meets biophysics: Visualizing the interaction of hypoxia-inducible factor 1α with p300 and CBP
2002 StandoutNobel
Asymmetric Methoxyselenenylation of Alkenes with Chiral Ferrocenylselenium Reagents
1997
A Genetically Encoded Boronate‐Containing Amino Acid
2008
2,6-Bis[(2S)-tetrahydrofuran-2-yl]phenyl diselenide: An effective reagent for asymmetric electrophilic addition reactions to olefins
1997
Organoselenium Chemistry in Stereoselective Reactions
2000
Proteasome Inhibitors Block Development of Plasmodium spp
1998 StandoutNobel
Iterative in Situ Click Chemistry Assembles a Branched Capture Agent and Allosteric Inhibitor for Akt1
2011 StandoutNobel
Anti-Thyroid Drugs and Thyroid Hormone Synthesis: Effect of Methimazole Derivatives on Peroxidase-Catalyzed Reactions
2005
First Total Synthesis of (+)‐Membrine
1997
Copper-Catalyzed Synthesis of Mixed Alkyl Aryl Phosphonates
2014 StandoutNobel
Nuclear Permeable Ruthenium(II) β-Carboline Complexes Induce Autophagy To Antagonize Mitochondrial-Mediated Apoptosis
2010
The medicinal chemist's toolbox for late stage functionalization of drug-like molecules
2015
Mechanistic Course of the Asymmetric Methoxyselenenylation Reaction
1998
IκB Kinase Is an Essential Component of the Tpl2 Signaling Pathway
2004
Ribosomal Synthesis of Dehydroalanine-Containing Peptides
2006 StandoutNobel
Organoselenium Chemistry: Role of Intramolecular Interactions
2010 Standout
Eponemycin exerts its antitumor effect through the inhibition of proteasome function.
1999
Intermolecular C–H activation at benzylic positions: synthesis of (+)-imperanene and (−)-α-conidendrin
2003
The use of chiral diferrocenyl diselenides for highly selective asymmetric intramolecular selenocyclisation
1999
Synthesis of Optically Active Bifunctional Building Blocks through Enantioselective Copper-Catalyzed Allylic Alkylation Using Grignard Reagents
2007 StandoutNobel
Synthesis of chiral diferrocenyl diselenides and their application to asymmetric reactions
1994
Asymmetric arene-alkene cyclizations mediated by a chiral organoselenium reagent
1998
Nuclear redistribution of tonicity-responsive enhancer binding protein requires proteasome activity
2000
Catalytic Asymmetric Conjugate Addition and Allylic Alkylation with Grignard Reagents
2008 StandoutNobel
Asymmetric methoxyselenenylation of olefins using an optically active diaryl diselenide derived from d-mannitol
1995
Cancer Genome Landscapes
2013 StandoutScience
Synthesis of Diaryl Diselenides Having Chiral Pyrrolidine Rings with C2 Symmetry. Their Application to the Asymmetric Methoxyselenenylation of trans-β-Methylstyrenes
1994
Synthesis and Diastereoselective Reactions of N,N-Dibenzylamino Aldehydes and Related Compounds
1999
Epoxomicin, a potent and selective proteasome inhibitor, exhibitsin vivoantiinflammatory activity
1999
Peptide blockade of HIFα degradation modulates cellular metabolism and angiogenesis
2002 StandoutNobel
Chemomimetic Biocatalysis: Exploiting the Synthetic Potential of Cofactor-Dependent Enzymes To Create New Catalysts
2015 StandoutNobel
Chiral selenium compounds in organic synthesis
1999
Impact of Natural Products on Developing New Anti-Cancer Agents
2009 Standout
A highly selective asymmetric methoxyselenylation of alkenes with a chiral ferrocenylselenium reagent
1994
Regiocontrol by the carbon-carbon double bond in the Rh2(OAc)4 mediated carbon-hydrogen insertion of α-diazo-ketones.
1991
De Novo Carborane-Containing Macrocyclic Peptides Targeting Human Epidermal Growth Factor Receptor
2019 StandoutNobel
Chiral Diselenides in Asymmetric Cyclization Reactions
1998
Copper-catalyzed asymmetric conjugate addition of Grignard reagents to cyclic enones
2004 StandoutNobel
A Chemically Functionalizable Nanoporous Material [Cu 3 (TMA) 2 (H 2 O) 3 ] n
1999 StandoutScience
Asymmetric Reaction of Arylalkenes with Diselenides
1995
Arylfluorosulfates Inactivate Intracellular Lipid Binding Protein(s) through Chemoselective SuFEx Reaction with a Binding Site Tyr Residue
2016 StandoutNobel
Selective proteasome inhibitors: modulators of antigen presentation?
1999
Proteasome inhibitors: valuable new tools for cell biologists
1998
Regulation and Cellular Roles of Ubiquitin-Specific Deubiquitinating Enzymes
2009
THE UBIQUITIN SYSTEM
1998 StandoutNobel
Altered ubiquitination and stability of aquaporin-1 in hypertonic stress
2001 StandoutNobel
Catalytic C−H Insertions Using Iron(III) Porphyrin Complexes
2008
Irreversible Inhibitors of Serine, Cysteine, and Threonine Proteases
2002 Standout
Stereoelectronic Effect for the Selectivity in C−H Insertion of Alkylidene Carbenes and Its Application to the Synthesis of Platensimycin
2009
“Inverse Drug Discovery” Strategy To Identify Proteins That Are Targeted by Latent Electrophiles As Exemplified by Aryl Fluorosulfates
2017 StandoutNobel
Catalytic Enantioselective C−H Activation by Means of Metal−Carbenoid-Induced C−H Insertion
2003
Catalytic Asymmetric Vinylogous Prins Cyclization: A Highly Diastereo- and Enantioselective Entry to Tetrahydrofurans
2016 StandoutNobel
Enantioselective Total Synthesis of Nigelladine A via Late-Stage C–H Oxidation Enabled by an Engineered P450 Enzyme
2017 StandoutNobel
Insertion reactions of electrophilic iron carbene complexes with organosilanes: a synthetic and mechanistic study
1995
Mutation of the E6-AP Ubiquitin Ligase Reduces Nuclear Inclusion Frequency While Accelerating Polyglutamine-Induced Pathology in SCA1 Mice
1999 StandoutNobel
Works of Louis Grenier being referenced
Design, Synthesis, and Biological Evaluation of Hydroquinone Derivatives of 17-Amino-17-demethoxygeldanamycin as Potent, Water-Soluble Inhibitors of Hsp90
2006
Mechanistic Studies on the Inactivation of the Proteasome by Lactacystin in Cultured Cells
1997
Active Site-directed Inhibitors of Rhodococcus 20 S Proteasome
1997
Mechanistic Studies on the Inactivation of the Proteasome by Lactacystin
1996
Novel IKK inhibitors: β-carbolines
2003
Potent and selective inhibitors of the proteasome: Dipeptidyl boronic acids
1998
Kinetic Studies on the Inhibition of Isopeptidase T by Ubiquitin Aldehyde
1996
Asymmetric selenomethoxylation of olefins involving a chiral C2 symmetrical electrophilic organoselenium reagent
1993
Diastereoselectivity in the Synthesis of 3(2H)-Furanones. Total Synthesis of (+)-Muscarine
1989
A Novel and Efficient Synthesis of a Highly Active Analogue of clasto-Lactacystin β-Lactone
1999
Rhodium acetate catalyzes the addition of carbenoids α- to ether oxygens
1989
Kinetic Studies of the Branched Chain Amino Acid Preferring Peptidase Activity of the 20S Proteasome: Development of a Continuous Assay and Inhibition by Tripeptide Aldehydes and clasto-Lactacystin β-Lactone
1998
Practical, Stereoselective Synthesis of Palinavir, a Potent HIV Protease Inhibitor
1997