Citation Impact
Citing Papers
Toll-like receptor 9 mediates innate immune activation by the malaria pigment hemozoin
2005
SuFEx-enabled, agnostic discovery of covalent inhibitors of human neutrophil elastase
2019 StandoutNobel
Endosomal TLR signaling is required for anti-nucleic acid and rheumatoid factor autoantibodies in lupus
2009 StandoutNobel
Chimeric spike mRNA vaccines protect against Sarbecovirus challenge in mice
2021 StandoutScienceNobel
Species-Specific Recognition of Single-Stranded RNA via Toll-like Receptor 7 and 8
2004 StandoutScience
Innate Antiviral Responses by Means of TLR7-Mediated Recognition of Single-Stranded RNA
2004 StandoutScience
Toll Pathway-Dependent Blockade of CD4 + CD25 + T Cell-Mediated Suppression by Dendritic Cells
2003 StandoutScience
Role of Adaptor TRIF in the MyD88-Independent Toll-Like Receptor Signaling Pathway
2003 StandoutScience
Immune Control of Tuberculosis by IFN-γ-Inducible LRG-47
2003 StandoutScience
CpG Motifs in Bacterial DNA Activate Leukocytes Through the pH-Dependent Generation of Reactive Oxygen Species
1998
TLR9 Blockade Inhibits Activation of Diabetogenic CD8+ T Cells and Delays Autoimmune Diabetes
2010
Group A Streptococcus Activates Type I Interferon Production and MyD88-dependent Signaling without Involvement of TLR2, TLR4, and TLR9
2008 StandoutNobel
Discovery and functional interrogation of SARS-CoV-2 RNA-host protein interactions
2021 StandoutNobel
Modeling pathogenesis of emergent and pre-emergent human coronaviruses in mice
2018
Replication-Competent Vesicular Stomatitis Virus Vaccine Vector Protects against SARS-CoV-2-Mediated Pathogenesis in Mice
2020
A Toll-like receptor recognizes bacterial DNA
2000 StandoutNature
Recognition of double-stranded RNA and activation of NF-κB by Toll-like receptor 3
2001 StandoutNature
Coronaviruses post-SARS: update on replication and pathogenesis
2009
mRNA Is an Endogenous Ligand for Toll-like Receptor 3
2004 StandoutNobel
Genetic analysis of resistance to viral infection
2007 StandoutNobel
Pathogenesis of SARS-CoV-2 in Transgenic Mice Expressing Human Angiotensin-Converting Enzyme 2
2020
Toll-like Receptors and Innate Immunity
2001
Inflammasome-mediated dysbiosis regulates progression of NAFLD and obesity
2012 StandoutNature
Recognition of microorganisms and activation of the immune response
2007 StandoutNature
Mechanisms of Host Receptor Adaptation by Severe Acute Respiratory Syndrome Coronavirus
2012
Smad-dependent and Smad-independent pathways in TGF-β family signalling
2003 StandoutNature
Pattern Recognition Receptors and Inflammation
2010 Standout
CpG DNA rescues B cells from apoptosis by activating NFκB and preventing mitochondrial membrane potential disruption via a chloroquine-sensitive pathway
1999
Transmissibility and transmission of respiratory viruses
2021
Toll-like receptors in systemic autoimmune disease
2006
Malarial Hemozoin Is a Nalp3 Inflammasome Activating Danger Signal
2009
Endocytosis of HIV-1 activates plasmacytoid dendritic cells via Toll-like receptor- viral RNA interactions
2005
Toll-Like Receptors and Activation of Autoreactive B Cells
2002
Direct Immunologic activities of CpG DNA and implications for gene therapy
1999
TLR9 signals after translocating from the ER to CpG DNA in the lysosome
2004
Structure, Function, and Antigenicity of the SARS-CoV-2 Spike Glycoprotein
2020 Standout
Dipeptidyl peptidase 4 is a functional receptor for the emerging human coronavirus-EMC
2013 StandoutNature
The role of CpG motifs in innate immunity
2000
Pathogenesis and transmission of SARS-CoV-2 in golden hamsters
2020 Nature
Bacterial CpG DNA Activates Immune Cells to Signal Infectious Danger
1999
Coronavirus Pathogenesis
2011
A mouse-adapted model of SARS-CoV-2 to test COVID-19 countermeasures
2020 Nature
Structure of the SARS-CoV-2 spike receptor-binding domain bound to the ACE2 receptor
2020 StandoutNature
The Inflammasomes
2010 Standout
Identification of Lps2 as a key transducer of MyD88-independent TIR signalling
2003 StandoutNatureNobel
CpG DNA and LPS induce distinct patterns of activation in human monocytes
1999
The Unc93b1 mutation 3d disrupts exogenous antigen presentation and signaling via Toll-like receptors 3, 7 and 9
2006 StandoutNobel
Recognition of Hyaluronan Released in Sterile Injury Involves a Unique Receptor Complex Dependent on Toll-like Receptor 4, CD44, and MD-2
2007 StandoutNobel
CpG-oligodeoxynucleotides co-stimulate primary T cells in the absence of antigen-presenting cells
1999
Toll‐like receptors, endogenous ligands, and systemic autoimmune disease
2005
SARS-CoV replication and pathogenesis in an in vitro model of the human conducting airway epithelium
2007
Chromatin–IgG complexes activate B cells by dual engagement of IgM and Toll-like receptors
2002 StandoutNature
Bacterial DNA as immune cell activator
1998
A Mouse-Adapted SARS-CoV-2 Induces Acute Lung Injury and Mortality in Standard Laboratory Mice
2020
STING is an endoplasmic reticulum adaptor that facilitates innate immune signalling
2008 StandoutNature
TLR2 synergizes with both TLR4 and TLR9 for induction of the MyD88-dependent splenic cytokine and chemokine response to Streptococcus pneumoniae
2007
Transient in vivo activation of rat brain macrophages/microglial cells and astrocytes by immunostimulatory multiple CpG oligonucleotides
2001
Inferences, questions and possibilities in Toll-like receptor signalling
2004 StandoutNatureNobel
Pathogen Recognition and Innate Immunity
2006 Standout
SARS-CoV-2 vaccines in development
2020 StandoutNature
Structural basis of receptor recognition by SARS-CoV-2
2020 StandoutNature
Infection in the Pathogenesis and Course of Chronic Obstructive Pulmonary Disease
2008
Drosophila Toll is activated by Gram-positive bacteria through a circulating peptidoglycan recognition protein
2001 StandoutNatureNobel
Pathophysiology and Management of Pulmonary Infections in Cystic Fibrosis
2003 Standout
Global Strategy for the Diagnosis, Management, and Prevention of Chronic Obstructive Pulmonary Disease
2012 Standout
Structural Analysis of Major Species Barriers between Humans and Palm Civets for Severe Acute Respiratory Syndrome Coronavirus Infections
2008
RTP4 inhibits IFN-I response and enhances experimental cerebral malaria and neuropathology
2020 StandoutNobel
Regulation of Smad signaling by protein kinase C
2001
Rapid induction of mitogen-activated protein kinases by immune stimulatory CpG DNA.
1998
Toll‐like receptor 9 binds single‐stranded CpG‐DNA in a sequence‐ and pH‐dependent manner
2004
Mice with mutations of Dock7 have generalized hypopigmentation and white-spotting but show normal neurological function
2009 StandoutNobel
Interactions Between the Microbiota and the Immune System
2012 StandoutScience
Flt3 permits survival during infection by rendering dendritic cells competent to activate NK cells
2010 StandoutNobel
Cutting Edge: Rapid Induction of Mitogen-Activated Protein Kinases by Immune Stimulatory CpG DNA
1998
Molecular pathology of emerging coronavirus infections
2014
CpG Motifs in Bacterial DNA and Their Immune Effects
2002 Standout
Cutting Edge: Bacterial DNA and LPS Act in Synergy in Inducing Nitric Oxide Production in RAW 264.7 Macrophages
1999
Extracellular DNA Required for Bacterial Biofilm Formation
2002 StandoutScience
Inflammation and autoimmunity caused by a SHP1 mutation depend on IL-1, MyD88, and a microbial trigger
2008 StandoutNobel
Cryo-EM structure of the 2019-nCoV spike in the prefusion conformation
2020 StandoutScience
Receptor Recognition by the Novel Coronavirus from Wuhan: an Analysis Based on Decade-Long Structural Studies of SARS Coronavirus
2020 Standout
CpG DNA Rescue from Anti-IgM-Induced WEHI-231 B Lymphoma Apoptosis via Modulation of IκBα and IκBβ and Sustained Activation of Nuclear Factor-κB/c-Rel
1998
Role of infection and antimicrobial therapy in acute exacerbations of chronic obstructive pulmonary disease
2006
Bacterial/CpG DNA Down-Modulates Colony Stimulating Factor-1 Receptor Surface Expression on Murine Bone Marrow-Derived Macrophages with Concomitant Growth Arrest and Factor-Independent Survival
1999
A Subset of Toll-Like Receptor Ligands Induces Cross-presentation by Bone Marrow-Derived Dendritic Cells
2003
Enhancement of Innate Immunity againstMycobacterium aviumInfection by Immunostimulatory DNA Is Mediated by Indoleamine 2,3-Dioxygenase
2001
CpG DNA rescue from anti-IgM-induced WEHI-231 B lymphoma apoptosis via modulation of I kappa B alpha and I kappa B beta and sustained activation of nuclear factor-kappa B/c-Rel.
1998
The Role of Cell Surface Receptors in the Activation of Human B Cells by Phosphorothioate Oligonucleotides
2000
Regulation of Adaptive Immunity by the Innate Immune System
2010 StandoutScience
Toll-like receptors 9 and 3 as essential components of innate immune defense against mouse cytomegalovirus infection
2004 StandoutNobel
A Novel Coronavirus from Patients with Pneumonia in China, 2019
2020 Standout
Suppressors of Cytokine Signaling (SOCS)-1 and SOCS-3 Are Induced by CpG-DNA and Modulate Cytokine Responses in APCs
2001
CpG DNA: A potent signal for growth, activation, and maturation of human dendritic cells
1999
Now I know my CpGs
2001
Mechanism and Function of a Newly Identified CpG DNA Motif in Human Primary B Cells
2000
HIV-1-infected monocyte-derived dendritic cells do not undergo maturation but can elicit IL-10 production and T cell regulation
2004 StandoutNobel
CpG-DNA-specific activation of antigen-presenting cells requires stress kinase activity and is preceded by non-specific endocytosis and endosomal maturation
1998
Airborne transmission of respiratory viruses
2021 StandoutScience
ATP-sensitive potassium channel (K ATP )–dependent regulation of cardiotropic viral infections
2011 StandoutNobel
Works of Lori Manzel being referenced
Lethal Infection of K18- hACE2 Mice Infected with Severe Acute Respiratory Syndrome Coronavirus
2006
Immunostimulatory CpG-oligodeoxynucleotides induce a factor that inhibits macrophage adhesion
1999
Protein kinase C is not necessary for transforming growth factor beta-induced growth-arrest in leukemia cell lines
1997
Lack of Immune Stimulation by Immobilized CpG-Oligodeoxynucleotide
1999
Unmethylated CpG‐containing oligodeoxynucleotides inhibit apoptosis in WEHI 231 B lymphocytes induced by several agents: evidence for blockade of apoptosis at a distal signalling step
1997
Structure-activity relationship analysis of substituted 4-quinolinamines, antagonists of immunostimulatory CpG-oligodeoxynucleotides
1999
Haemophilus influenzae from Patients with Chronic Obstructive Pulmonary Disease Exacerbation Induce More Inflammation than Colonizers
2005
Inflammatory Response in Airway Epithelial Cells Isolated from Patients with Cystic Fibrosis
2002
Antagonism of Immunostimulatory CpG-Oligodeoxynucleotides by Quinacrine, Chloroquine, and Structurally Related Compounds
1998
Antagonism of Immunostimulatory CpG-Oligodeoxynucleotides by 4-Aminoquinolines and Other Weak Bases: Mechanistic Studies
1999