Citation Impact
Citing Papers
Molecular Architecture of a Eukaryotic Translational Initiation Complex
2013 ScienceNobel
Genome-Wide Analysis in Vivo of Translation with Nucleotide Resolution Using Ribosome Profiling
2009 StandoutScience
Protein interaction networks revealed by proteome coevolution
2019 StandoutScienceNobel
A Sulfilimine Bond Identified in Collagen IV
2009 StandoutScienceNobel
Sequencing and Analysis of Neanderthal Genomic DNA
2006 StandoutScienceNobel
Structure of the human TRPM4 ion channel in a lipid nanodisc
2017 StandoutScienceNobel
Dom34:Hbs1 Promotes Subunit Dissociation and Peptidyl-tRNA Drop-Off to Initiate No-Go Decay
2010 Science
Maximum-Likelihood Estimation of Demographic Parameters Using the Frequency Spectrum of Unlinked Single-Nucleotide Polymorphisms
2004
Structural Roles for Human Translation Factor eIF3 in Initiation of Protein Synthesis
2005 StandoutScienceNobel
The structure of the 80S ribosome from Trypanosoma cruzi reveals unique rRNA components
2005 StandoutNobel
The emerging biology of RNA post-transcriptional modifications
2016
The UK Biobank resource with deep phenotyping and genomic data
2018 StandoutNature
Structure of eIF3b RNA Recognition Motif and Its Interaction with eIF3j
2006
The Indispensable N-Terminal Half of eIF3j/HCR1 Cooperates with its Structurally Conserved Binding Partner eIF3b/PRT1-RRM and with eIF1A in Stringent AUG Selection
2010
PCI proteins eIF3e and eIF3m define distinct translation initiation factor 3 complexes
2005
Translation Initiation Factor eIF4G-1 Binds to eIF3 through the eIF3e Subunit
2006
An integrated map of genetic variation from 1,092 human genomes
2012 StandoutNature
Structure of a mammalian ryanodine receptor
2014 StandoutNatureNobel
Molecular Architecture of the 40S⋅eIF1⋅eIF3 Translation Initiation Complex
2014
Mutually Cooperative Binding of Eukaryotic Translation Initiation Factor (eIF) 3 and eIF4A to Human eIF4G-1
2000
Position of eukaryotic initiation factor eIF1 on the 40S ribosomal subunit determined by directed hydroxyl radical probing
2003
Superfamily Assignments for the Yeast Proteome through Integration of Structure Prediction with the Gene Ontology
2007 StandoutNobel
Crystal Structure of ADP-ribosylated Ribosomal Translocase from Saccharomyces cerevisiae
2004
Topology of the human and mouse m6A RNA methylomes revealed by m6A-seq
2012 StandoutNature
Genetic effects on gene expression across human tissues
2017 StandoutNature
Translation Elongation Factor 2 Anticodon Mimicry Domain Mutants Affect Fidelity and Diphtheria Toxin Resistance
2006
The yeast eIF3 subunits TIF32/a, NIP1/c, and eIF5 make critical connections with the 40S ribosome in vivo
2003
Grand Challenge Commentary: RNA epigenetics?
2010
Communication Between Eukaryotic Translation Initiation Factors 1 and 1A on the Yeast Small Ribosomal Subunit
2003
The Pfam Protein Families Database
2002 Standout
Uncoupling of Initiation Factor eIF5B/IF2 GTPase and Translational Activities by Mutations that Lower Ribosome Affinity
2002
Functions of eIF3 downstream of 48S assembly impact AUG recognition and GCN4 translational control
2004
Structural analysis of an eIF3 subcomplex reveals conserved interactions required for a stable and proper translation pre-initiation complex assembly
2011
The genomic landscape of Neanderthal ancestry in present-day humans
2014 StandoutNatureNobel
Structure and interactions of the translation initiation factor eIF1
1999
The Cryo-EM Structure of a Translation Initiation Complex from Escherichia coli
2005 StandoutNobel
Structural Characterization of the Human Eukaryotic Initiation Factor 3 Protein Complex by Mass Spectrometry
2007 StandoutNobel
A Conformational Change in the Eukaryotic Translation Preinitiation Complex and Release of eIF1 Signal Recognition of the Start Codon
2005
Hepatitis-C-virus-like internal ribosome entry sites displace eIF3 to gain access to the 40S subunit
2013 StandoutNatureNobel
Gene-Specific Regulation by General Translation Factors
2002
The Human Protein HSPC021 Interacts with Int-6 and Is Associated with Eukaryotic Translation Initiation Factor 3
2001
Domains of eIF1A that mediate binding to eIF2, eIF3 and eIF5B and promote ternary complex recruitment in vivo
2003
Release of initiation factors from 48S complexes during ribosomal subunit joining and the link between establishment of codon-anticodon base-pairing and hydrolysis of eIF2-bound GTP
2004
Database resources of the National Center for Biotechnology Information: update
2003 Standout
‘Ribozoomin’ – Translation Initiation from the Perspective of the Ribosome-bound Eukaryotic Initiation Factors (eIFs)
2012
PCI Complexes: Beyond the Proteasome, CSN, and eIF3 Troika
2009
GTP-dependent Recognition of the Methionine Moiety on Initiator tRNA by Translation Factor eIF2
2003
Minimal Methylated Substrate and Extended Substrate Range of Escherichia coli AlkB Protein, a 1-Methyladenine-DNA Dioxygenase
2003 StandoutNobel
Structure of a Yeast 40S–eIF1–eIF1A–eIF3–eIF3j initiation complex
2015
Dissecting the genetics of the human transcriptome identifies novel trait-relatedtrans-eQTLs and corroborates the regulatory relevance of non-protein coding loci
2015
Cap-dependent and cap-independent translation in eukaryotic systems
2004
eIF3j Is Located in the Decoding Center of the Human 40S Ribosomal Subunit
2007 StandoutNobel
Characterization of cDNAs Encoding the p44 and p35 Subunits of Human Translation Initiation Factor eIF3
1998
Distinct Regions of Human eIF3 Are Sufficient for Binding to the HCV IRES and the 40S Ribosomal Subunit
2010
Structure of mammalian eIF3 in the context of the 43S preinitiation complex
2015 StandoutNatureNobel
Efficient Incorporation of Eukaryotic Initiation Factor 1 into the Multifactor Complex Is Critical for Formation of Functional Ribosomal Preinitiation Complexes in Vivo
2004
Individual Overexpression of Five Subunits of Human Translation Initiation Factor eIF3 Promotes Malignant Transformation of Immortal Fibroblast Cells
2006
An intact conformation at the tip of elongation factor G domain IV is functionally important
1998
Starting the protein synthesis machine: eukaryotic translation initiation
2003
Reconstitution reveals the functional core of mammalian eIF3
2007
Dual Function of eIF3j/Hcr1p in Processing 20 S Pre-rRNA and Translation Initiation
2001
The NHGRI GWAS Catalog, a curated resource of SNP-trait associations
2013 Standout
PCI complexes: pretty complex interactions in diverse signaling pathways
2001
eIF3: a versatile scaffold for translation initiation complexes
2006
The Arabidopsis homologue of an eIF3 complex subunit associates with the COP9 complex1
1998
Conserved bipartite motifs in yeast eIF5 and eIF2Bepsilon , GTPase-activating and GDP-GTP exchange factors in translation initiation, mediate binding to their common substrate eIF2
1999
An early modern human from Romania with a recent Neanderthal ancestor
2015 StandoutNatureNobel
Elongation Factor 2 as a Novel Target for Selective Inhibition of Fungal Protein Synthesis
1998
The Saccharomyces cerevisiae HCR1 Gene Encoding a Homologue of the p35 Subunit of Human Translation Initiation Factor 3 (eIF3) Is a High Copy Suppressor of a Temperature-sensitive Mutation in the Rpg1p Subunit of Yeast eIF3
1999
Cryo-EM Visualization of a Viral Internal Ribosome Entry Site Bound to Human Ribosomes
2004 StandoutNobel
Translation Initiation Factor eIF3b Contains a Nine-Bladed β-Propeller and Interacts with the 40S Ribosomal Subunit
2014
Intracellular translation initiation factor levels in Saccharomyces cerevisiae and their role in cap‐complex function
2002
The Eukaryotic Translation Initiation Factors eIF1 and eIF1A Induce an Open Conformation of the 40S Ribosome
2007 StandoutNobel
Direct eIF2-eIF3 contact in the multifactor complex is important for translation initiation in vivo
2002
Pi Release from eIF2, Not GTP Hydrolysis, Is the Step Controlled by Start-Site Selection during Eukaryotic Translation Initiation
2005
Melanoma-intrinsic β-catenin signalling prevents anti-tumour immunity
2015 StandoutNature
N6-methyladenosine-dependent regulation of messenger RNA stability
2013 StandoutNature
Inference of human population history from individual whole-genome sequences
2011 StandoutNature
Characterization of eIF3k
2003
Communication between Eukaryotic Translation Initiation Factors 5 and 1A within the Ribosomal Pre-initiation Complex Plays a Role in Start Site Selection
2005
Mammalian Translation Initiation Factor eIF1 Functions with eIF1A and eIF3 in the Formation of a Stable 40 S Preinitiation Complex
2003
Crystal Structure of Human eIF3k, the First Structure of eIF3 Subunits
2004
Structures of modified eEF2·80S ribosome complexes reveal the role of GTP hydrolysis in translocation
2007 StandoutNobel
Molecular interaction between human tumor marker protein p150, the largest subunit of eIF3, and intermediate filament protein K7
2001
Preparation and activity of synthetic unmodified mammalian tRNAi Met in initiation of translation in vitro
2001
Yeast strains with N-terminally truncated ribosomal protein S5: implications for the evolution, structure and function of the Rps5/Rps7 proteins
2009
The Human Condition—A Molecular Approach
2014 StandoutNobel
Rpg1p/Tif32p, a Subunit of Translation Initiation Factor 3, Interacts with Actin-Associated Protein Sla2p
2001
Affinity purification of eukaryotic 48S initiation complexes
2006
The eIF1A C‐terminal domain promotes initiation complex assembly, scanning and AUG selection in vivo
2005
Identification and Characterization of the CLK1 Gene Product, a Novel CaM Kinase-like Protein Kinase from the Yeast Saccharomyces cerevisiae
1996
Related eIF3 subunits TIF32 and HCR1 interact with an RNA recognition motif in PRT1 required for eIF3 integrity and ribosome binding
2001
Small RNAs are modified with N-glycans and displayed on the surface of living cells
2021 StandoutNobel
The j-Subunit of Human Translation Initiation Factor eIF3 Is Required for the Stable Binding of eIF3 and Its Subcomplexes to 40 S Ribosomal Subunits in Vitro
2004 StandoutNobel
Structure of the Mammalian Ribosomal 43S Preinitiation Complex Bound to the Scanning Factor DHX29
2013 StandoutNobel
The translation initiation complex eIF3 in trypanosomatids and other pathogenic excavates – identification of conserved and divergent features based on orthologue analysis
2014
Insight into the Catalytic Mechanism of Pseudomonas aeruginosa Exotoxin A
2002
The structure of LepA, the ribosomal back translocase
2008 StandoutNobel
Mutational Analysis of Mammalian Translation Initiation Factor 5 (eIF5): Role of Interaction between the β Subunit of eIF2 and eIF5 in eIF5 Function In Vitro and In Vivo
2000
Tetrahymena proteins p80 and p95 are not core telomerase components
2001 StandoutNobel
Recognition of Nascent RNA by the Human La Antigen: Conserved and Divergent Features of Structure and Function
2001
Molecular Mechanism of Scanning and Start Codon Selection in Eukaryotes
2011
Elongation factor 2 mutants deficient in diphthamide formation show temperature-sensitive cell growth.
1994
Structural characterization of mRNA-tRNA translocation intermediates
2012 StandoutNobel
The RNA Recognition Motif of Eukaryotic Translation Initiation Factor 3g (eIF3g) Is Required for Resumption of Scanning of Posttermination Ribosomes for Reinitiation on GCN4 and Together with eIF3i Stimulates Linear Scanning
2010
eIF3d is an mRNA cap-binding protein that is required for specialized translation initiation
2016 StandoutNatureNobel
Naive Bayesian Classifier for Rapid Assignment of rRNA Sequences into the New Bacterial Taxonomy
2007 Standout
Rational HIV Immunogen Design to Target Specific Germline B Cell Receptors
2013 StandoutScienceNobel
Structural integrity of the PCI domain of eIF3a/TIF32 is required for mRNA recruitment to the 43S pre-initiation complexes
2014
Interactions of Eukaryotic Translation Initiation Factor 3 (eIF3) Subunit NIP1/c with eIF1 and eIF5 Promote Preinitiation Complex Assembly and Regulate Start Codon Selection
2004
The Molecular Mechanics of Eukaryotic Translation
2004
Changes in Ribosomal Binding Activity of eIF3 Correlate with Increased Translation Rates during Activation of T Lymphocytes
2005
The Structure of the Ribosome with Elongation Factor G Trapped in the Posttranslocational State
2009 StandoutScienceNobel
The Yeast Eukaryotic Initiation Factor 4G (eIF4G) HEAT Domain Interacts with eIF1 and eIF5 and Is Involved in Stringent AUG Selection
2003
Nuclear and mitochondrial DNA sequences from two Denisovan individuals
2015 StandoutNobel
TRANSLATIONAL REGULATION OFGCN4AND THE GENERAL AMINO ACID CONTROL OF YEAST
2005
Cryo-EM structure of the mammalian eukaryotic release factor eRF1–eRF3-associated termination complex
2012 StandoutNobel
Initiation factor eIF5B catalyzes second GTP-dependent step in eukaryotic translation initiation
2002
The process of mRNA–tRNA translocation
2007 StandoutNobel
Interaction of the RNP1 Motif in PRT1 with HCR1 Promotes 40S Binding of Eukaryotic Initiation Factor 3 in Yeast
2006
The Ubiquitin-Proteasome Proteolytic Pathway: Destruction for the Sake of Construction
2002 StandoutNobel
Statistical evaluation of alternative models of human evolution
2007
Functional reconstitution of human eukaryotic translation initiation factor 3 (eIF3)
2011 StandoutNobel
The Allele Frequency Spectrum in Genome-Wide Human Variation Data Reveals Signals of Differential Demographic History in Three Large World Populations
2004
Mass spectrometry reveals modularity and a complete subunit interaction map of the eukaryotic translation factor eIF3
2008 StandoutNobel
Alternative mechanisms of initiating translation of mammalian mRNAs
2005
Targeted Investigation of the Neandertal Genome by Array-Based Sequence Capture
2010 StandoutScienceNobel
Cap-Independent Translation Is Required for Starvation-Induced Differentiation in Yeast
2007 StandoutScienceNobel
Coordinated assembly of human translation initiation complexes by the hepatitis C virus internal ribosome entry site RNA
2004 StandoutNobel
Interrogating multiple aspects of variation in a full resequencing data set to infer human population size changes
2005
The C-Terminal Region of Eukaryotic Translation Initiation Factor 3a (eIF3a) Promotes mRNA Recruitment, Scanning, and, Together with eIF3j and the eIF3b RNA Recognition Motif, Selection of AUG Start Codons
2010
Structure of an archaeal heterotrimeric initiation factor 2 reveals a nucleotide state between the GTP and the GDP states
2007
Alternative mechanisms of initiating translation of mammalian mRNAs
2005
Works of Lon Phan being referenced
SPDI: data model for variants and applications at NCBI
2019
The essential Gcd10p–Gcd14p nuclear complex is required for 1-methyladenosine modification and maturation of initiator methionyl-tRNA
1998
Fission Yeast Homolog of Murine Int-6 Protein, Encoded by Mouse Mammary Tumor Virus Integration Site, Is Associated with the Conserved Core Subunits of Eukaryotic Translation Initiation Factor 3
2001
Development and characterization of a reconstituted yeast translation initiation system
2002
Analysis and reconstitution of translation initiation in vitro
2002
Complex Formation by All Five Homologues of Mammalian Translation Initiation Factor 3 Subunits from Yeast Saccharomyces cerevisiae
1998
A subcomplex of three eIF3 subunits binds eIF1 and eIF5 and stimulates ribosome binding of mRNA and tRNAiMet
2001
Study of Translational Control of Eukaryotic Gene Expression Using Yeast
2004
Nip1p Associates with 40 S Ribosomes and the Prt1p Subunit of Eukaryotic Initiation Factor 3 and Is Required for Efficient Translation Initiation
1998
Control of Transfer RNA Maturation by Phosphorylation of the Human La Antigen on Serine 366
2000
Saccharomyces cerevisiae Protein Pci8p and Human Protein eIF3e/Int-6 Interact with the eIF3 Core Complex by Binding to Cognate eIF3b Subunits
2001
Phenotype–Genotype Integrator (PheGenI): synthesizing genome-wide association study (GWAS) data with existing genomic resources
2013
A Multifactor Complex of eIF1, eIF2, eIF3, eIF5, and tRNAiMet Promotes Initiation Complex Assembly and Couples GTP Hydrolysis to AUG Recognition
2001
Sequence variations in the public human genome data reflect a bottlenecked population history
2002
Saccharomyces cerevisiae elongation factor 2. Genetic cloning, characterization of expression, and G-domain modeling.
1992
Identification of a Translation Initiation Factor 3 (eIF3) Core Complex, Conserved in Yeast and Mammals, That Interacts with eIF5
1998
Saccharomyces cerevisiae elongation factor 2. Mutagenesis of the histidine precursor of diphthamide yields a functional protein that is resistant to diphtheria toxin.
1993
Conserved bipartite motifs in yeast eIF5 and eIF2Bε, GTPase-activating and GDP–GTP exchange factors in translation initiation, mediate binding to their common substrate eIF2
1999
The Gcd10p/Gcd14p complex is the essential two-subunit tRNA(1-methyladenosine) methyltransferase of Saccharomyces cerevisiae
2000