Standout Papers
Citation Impact
Citing Papers
Cardiac Hypertrophy: The Good, the Bad, and the Ugly
2003 Standout
Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profiles
2005 Standout
Genomic Variation in Seven Khoe-San Groups Reveals Adaptation and Complex African History
2012 Science
Protein characterization of Saccharomyces cerevisiae RNA polymerase II after in vivo cross-linking
2007 StandoutNobel
Structural Basis of Transcription: Backtracked RNA Polymerase II at 3.4 Angstrom Resolution
2009 StandoutScienceNobel
Little Evidence for Developmental Plasticity of Adult Hematopoietic Stem Cells
2002 Science
In vivo imaging of hydrogen peroxide production in a murine tumor model with a chemoselective bioluminescent reporter
2010 StandoutNobel
The healing myocardium sequentially mobilizes two monocyte subsets with divergent and complementary functions
2007 Standout
Muscle-derived hematopoietic stem cells are hematopoietic in origin
2002
Determination of cell-cell adhesion in response to oxidants and antioxidants
1999
Hallmarks of Cancer: The Next Generation
2011 Standout
Hypoxia-Inducible Factors in Physiology and Medicine
2012 StandoutNobel
Heterogeneity of the Tumor Vasculature
2010
Chimerism of the Transplanted Heart
2002 Standout
Intramolecular Control of Protein Stability, Subnuclear Compartmentalization, and Coactivator Function of Peroxisome Proliferator-activated Receptor γ Coactivator 1α
2007
Universal Definition of Myocardial Infarction
2007 Standout
Hematopoietic, vascular and cardiac fates of bone marrow-derived stem cells
2002
Evidence That Human Cardiac Myocytes Divide after Myocardial Infarction
2001
Role of Tumour Necrosis Factor-?? in the Progression of Heart Failure
2000
In vivo enhancement of angiogenesis by adenoviral transfer of HIF-1α-modified endothelial progenitor cells (Ad-HIF-1α-modified EPC for angiogenesis)
2008
Prospects for Cardiovascular Research
2001 StandoutNobel
Myocyte renewal and ventricular remodelling
2002 Nature
Adora2b-elicited Per2 stabilization promotes a HIF-dependent metabolic switch crucial for myocardial adaptation to ischemia
2012
Diabetes impairs progenitor cell mobilisation after hindlimb ischaemia–reperfusion injury in rats
2006
Chronic inhibition of cyclic GMP phosphodiesterase 5A prevents and reverses cardiac hypertrophy
2005 Standout
Recruitment of P-TEFb for Stimulation of Transcriptional Elongation by the Bromodomain Protein Brd4
2005
Haematopoietic stem cells do not transdifferentiate into cardiac myocytes in myocardial infarcts
2004 StandoutNature
Adult Cardiac Stem Cells Are Multipotent and Support Myocardial Regeneration
2003 Standout
The Evolving Concept of a Stem Cell
2001
Cardiac hypertrophy and failure: lessons learned from genetically engineered mice
2001
The Chk2 protein kinase
2004
Telomeres and cancer: a tale with many endings
2003
Endothelial Progenitor Cells
2004
The inflammatory response in myocardial infarction
2002 Standout
Cell Grafting for Cardiac Repair
2003
Adiponectin protects against myocardial ischemia-reperfusion injury through AMPK- and COX-2–dependent mechanisms
2005
Macrophage Depletion Impairs Wound Healing and Increases Left Ventricular Remodeling after Myocardial Injury in Mice
2007
Haematopoietic stem cells adopt mature haematopoietic fates in ischaemic myocardium
2004 StandoutNature
Hypoxia Rescues Frataxin Loss by Restoring Iron Sulfur Cluster Biogenesis
2019 StandoutNobel
Suppression of inflammation by a synthetic histone mimic
2010 StandoutNatureNobel
Skeletal Muscle Stem Cells Do Not Transdifferentiate Into Cardiomyocytes After Cardiac Grafting
2002
Myofibroblast and Endothelial Cell Proliferation during Murine Myocardial Infarct Repair
2003
RNA-based affinity purification reveals 7SK RNPs with distinct composition and regulation
2007
Surrogate Wnt agonists that phenocopy canonical Wnt and β-catenin signalling
2017 StandoutNatureNobel
Tumor necrosis factor-alpha and myocardial remodeling in progression of heart failure: a current perspective
2002
Adult hematopoietic stem cells provide functional hemangioblast activity during retinal neovascularization
2002
Hematopoietic and nonhematopoietic potentials of Hoechstlow/side population cells isolated from adult rat kidney
2004 StandoutNobel
Seven-transmembrane-spanning receptors and heart function
2002 StandoutNatureNobel
Ectopic Expression of the Catalytic Subunit of Telomerase Protects against Brain Injury Resulting from Ischemia and NMDA-Induced Neurotoxicity
2004
Elongation by RNA polymerase II: the short and long of it
2004
Adenovirus-mediated HIF-1α gene transfer promotes repair of mouse airway allograft microvasculature and attenuates chronic rejection
2011 StandoutNobel
Telomeres and human disease: ageing, cancer and beyond
2005
Distinct mouse coronary anatomy and myocardial infarction consequent to ligation
2005
The transcriptional coactivator PGC-1α is essential for maximal and efficient cardiac mitochondrial fatty acid oxidation and lipid homeostasis
2008
Cardiac expression of adiponectin and its receptors in streptozotocin-induced diabetic rats
2007
Oxygen Sensing, Homeostasis, and Disease
2011 StandoutNobel
Regulation of cardiac hypertrophy by intracellular signalling pathways
2006 Standout
Transcriptional control of mitochondrial biogenesis: the central role of PGC-1
2008
Myocyte and myogenic stem cell transplantation in the heart
2003
Telomerase modulates expression of growth-controlling genes and enhances cell proliferation
2003
Implantation of bone marrow stem cells reduces the infarction and fibrosis in ischemic mouse heart
2003
EGLN1 Inhibition and Rerouting of α-Ketoglutarate Suffice for Remote Ischemic Protection
2016 StandoutNobel
Interactions between endothelial nitric oxide synthase and sex hormones in vascular protection in mice
2002 StandoutNobel
Cardiac Remodeling in Obesity
2008
Cardiomyocyte Regeneration from Circulating Bone Marrow Cells in Mice
2003
Vascular permeability, vascular hyperpermeability and angiogenesis
2008
PGC-1 coactivators: inducible regulators of energy metabolism in health and disease
2006
Trex1 Exonuclease Degrades ssDNA to Prevent Chronic Checkpoint Activation and Autoimmune Disease
2007 StandoutNobel
Novel Role of NADPH Oxidase in Angiogenesis and Stem/Progenitor Cell Function
2009
Cardiomyocytes of Noncardiac Origin in Myocardial Biopsies of Human Transplanted Hearts
2002
Fibrosis, not cell size, delineates β-myosin heavy chain reexpression during cardiac hypertrophy and normal aging in vivo
2006 StandoutNobel
RNA–protein analysis using a conditional CRISPR nuclease
2013 StandoutNobel
Physiology and analysis of the electrocardiographic T wave in mice
2013
The continuing evolution of the Langendorff and ejecting murine heart: new advances in cardiac phenotyping
2012
Randomized, Double-Blind, Placebo-Controlled, Pilot Trial of Infliximab, a Chimeric Monoclonal Antibody to Tumor Necrosis Factor-α, in Patients With Moderate-to-Severe Heart Failure
2003 Standout
DNA enzyme targeting TNF-α mRNA improves hemodynamic performance in rats with postinfarction heart failure
2001
Myocardial Fatty Acid Metabolism in Health and Disease
2010 Standout
Interactions between endothelial nitric oxide synthase and sex hormones in vascular protection in mice
2002 StandoutNobel
Repair of Infarcted Myocardium by Autologous Intracoronary Mononuclear Bone Marrow Cell Transplantation in Humans
2002 Standout
Genetic Dissection of Cardiac Growth Control Pathways
2000
Divergent transcriptional responses to independent genetic causes of cardiac hypertrophy
2001
Anti–Tumor Necrosis Factor-α Antibody Limits Heart Failure in a Transgenic Model
2001
Differential expression of TNF-α, IL-6, and IGF-1 by graded mechanical stress in normal rat myocardium
2002
Assessment of Myocardial Viability With 99m Tc-Sestamibi Tomography Before Coronary Bypass Graft Surgery
1997
Biology of Hematopoietic Stem Cells and Progenitors: Implications for Clinical Application
2003
Overexpression of angiotensin AT 1 receptor transgene in the mouse myocardium produces a lethal phenotype associated with myocyte hyperplasia and heart block
1997 StandoutNobel
Genes and pathways downstream of telomerase in melanoma metastasis
2006 StandoutNobel
Cardiac hypertrophy and sudden death in mice with a genetically clamped renin transgene
2004 StandoutNobel
Mast Cells Exert Effects Outside the Central Nervous System to Influence Experimental Allergic Encephalomyelitis Disease Course
2003
Mobilized bone marrow cells repair the infarcted heart, improving function and survival
2001 Standout
Phenotype and hematopoietic potential of side population cells throughout embryonic development
2003
Hypertrophy, Pathology, and Molecular Markers of Cardiac Pathogenesis
1998
Pleistocene North African genomes link Near Eastern and sub-Saharan African human populations
2018 StandoutScienceNobel
Safety and Efficacy of a Soluble P75 Tumor Necrosis Factor Receptor (Enbrel, Etanercept) in Patients With Advanced Heart Failure
1999
Physiological Coupling of Donor and Host Cardiomyocytes After Cellular Transplantation
2003
Role of β2-integrins for homing and neovascularization capacity of endothelial progenitor cells
2004
Targeting the Receptor-G q Interface to Inhibit in Vivo Pressure Overload Myocardial Hypertrophy
1998 StandoutScienceNobel
Cardiac Overexpression of Monocyte Chemoattractant Protein-1 in Transgenic Mice Prevents Cardiac Dysfunction and Remodeling After Myocardial Infarction
2006
Evidence for Cardiomyocyte Repopulation by Extracardiac Progenitors in Transplanted Human Hearts
2002
Cytoplasmic Signaling Pathways That Regulate Cardiac Hypertrophy
2001
Cardiac Energy Metabolism in Obesity
2007
Endothelin induction of inositol phospholipid hydrolysis, sarcomere assembly, and cardiac gene expression in ventricular myocytes. A paracrine mechanism for myocardial cell hypertrophy
1990
Bone Marrow–Derived Cardiomyocytes Are Present in Adult Human Heart
2003
Soluble Tumor Necrosis Factor Receptor Abrogates Myocardial Inflammation but Not Hypertrophy in Cytokine-Induced Cardiomyopathy
2000
Transplantation of Progenitor Cells and Regeneration Enhancement in Acute Myocardial Infarction (TOPCARE-AMI)
2002 Standout
Ex Vivo Activated Human Macrophages Improve Healing, Remodeling, and Function of the Infarcted Heart
2006
Cardiac Function in Mice Overexpressing the β-Adrenergic Receptor Kinase or a βARK Inhibitor
1995 StandoutScienceNobel
Increased Nitric Oxide in Proportion to the Severity of Heart Failure in Patients With Dilated Cardiomyopathy. Close Correlation of Tumor Necrosis Factor-.ALPHA. With Systemic and Local Production of Nitric Oxide.
2002
Load-Dependent and -Independent Regulation of Proinflammatory Cytokine and Cytokine Receptor Gene Expression in the Adult Mammalian Heart
2002
Dynamic Imaging of Allogeneic Mesenchymal Stem Cells Trafficking to Myocardial Infarction
2005
Endothelial Progenitor Cells
2004 Standout
Myocardial expression of a constitutively active alpha 1B-adrenergic receptor in transgenic mice induces cardiac hypertrophy.
1994 StandoutNobel
Nonsynchronous accumulation of alpha-skeletal actin and beta-myosin heavy chain mRNAs during early stages of pressure-overload--induced cardiac hypertrophy demonstrated by in situ hybridization.
1989
Hypoxic retinal Müller cells promote vascular permeability by HIF-1–dependent up-regulation of angiopoietin-like 4
2013 StandoutNobel
Synergistic effect of HIF-1α gene therapy and HIF-1-activated bone marrow-derived angiogenic cells in a mouse model of limb ischemia
2009 StandoutNobel
Ligand-induced overexpression of a constitutively active β 2 -adrenergic receptor: Pharmacological creation of a phenotype in transgenic mice
1997 StandoutNobel
Adenoviral transfer of HIF-1α enhances vascular responses to critical limb ischemia in diabetic mice
2009 StandoutNobel
Cardiac Overexpression of a G q Inhibitor Blocks Induction of Extracellular Signal–Regulated Kinase and c-Jun NH 2 -Terminal Kinase Activity in In Vivo Pressure Overload
2001
Results of Targeted Anti–Tumor Necrosis Factor Therapy With Etanercept (ENBREL) in Patients With Advanced Heart Failure
2001
Hypoxia-inducible factor 1 is required for remote ischemic preconditioning of the heart
2013 StandoutNobel
Free Radicals in the Physiological Control of Cell Function
2002 Standout
Mitochondrial activation chemicals synergize with surface receptor PD-1 blockade for T cell-dependent antitumor activity
2017 StandoutNobel
Peroxisome Proliferator–Activated Receptor γ Coactivator-1 (PGC-1) Regulatory Cascade in Cardiac Physiology and Disease
2007
Human Mesenchymal Stem Cells Differentiate to a Cardiomyocyte Phenotype in the Adult Murine Heart
2002 Standout
JNK1 controls mast cell degranulation and IL-1β production in inflammatory arthritis
2010 StandoutNobel
Dual Channel Optical Tomographic Imaging of Leukocyte Recruitment and Protease Activity in the Healing Myocardial Infarct
2007
Works of Lloyd H. Michael being referenced
Short Communication: Ischemia/Reperfusion Tolerance Is Time-of-Day–Dependent
2009
Determinants of Cardiac Electrophysiological Properties in Mice
2004
Induction of the synthesis of the C-X-C chemokine interferon-γ-inducible protein-10 in experimental canine endotoxemia
2000
Regeneration of ischemic cardiac muscle and vascular endothelium by adult stem cells
2001 Standout
TAK1 is activated in the myocardium after pressure overload and is sufficient to provoke heart failure in transgenic mice
2000
Mast cells and macrophages in normal C57/BL/6 mice
2002
Activation of cardiac Cdk9 represses PGC‐1 and confers a predisposition to heart failure
2004
Stem Cell Plasticity in Muscle and Bone Marrow
2001
Effects of Isoflurane on Coronary Blood Flow Velocity in Young, Old and ApoE−/− Mice Measured by Doppler Ultrasound
2007
Activation and function of cyclin T–Cdk9 (positive transcription elongation factor-b) in cardiac muscle-cell hypertrophy
2002
Identification of Genes Regulated During Mechanical Load-induced Cardiac Hypertrophy
2000
Reactive Oxygen Intermediates Induce Monocyte Chemotactic Protein-1 in Vascular Endothelium after Brief Ischemia
2001
Effects of diet-induced obesity on inflammation and remodeling after myocardial infarction
2006
Of Mice and Dogs
2004
Regulation of ICAM‐1 and IL‐6 in Myocardial Ischemia: Effect of Reperfusion a
1994
Stem Cell Factor Induction Is Associated With Mast Cell Accumulation After Canine Myocardial Ischemia and Reperfusion
1998
Complement C5a, TGF-β1, and MCP-1, in Sequence, Induce Migration of Monocytes Into Ischemic Canine Myocardium Within the First One to Five Hours After Reperfusion
1997
Role of α 4 Integrin and VCAM-1 in CD18-Independent Neutrophil Migration Across Mouse Cardiac Endothelium
2002
Induction and suppression of interferon‐inducible protein (IP)‐10 in reperfused myocardial infarcts may regulate angiogenesis
2001
A hemodynamic load in vivo induces cardiac expression of the cellular oncogene, c-myc
1987
MEKK1 is essential for cardiac hypertrophy and dysfunction induced by Gq
2002
Morphological Characteristics of the Microvasculature in Healing Myocardial Infarcts
2002
Telomere attrition and Chk2 activation in human heart failure
2003
Myocardial infarction and remodeling in mice: effect of reperfusion
1999
IL-10 Is Induced in the Reperfused Myocardium and May Modulate the Reaction to Injury
2000
Resident Cardiac Mast Cells Degranulate and Release Preformed TNF-α, Initiating the Cytokine Cascade in Experimental Canine Myocardial Ischemia/Reperfusion
1998
Induction of Interleukin-6 Synthesis in the Myocardium
1995
CCL2/Monocyte Chemoattractant Protein-1 Regulates Inflammatory Responses Critical to Healing Myocardial Infarcts
2005
Endogenous tumor necrosis factor protects the adult cardiac myocyte against ischemic-induced apoptosis in a murine model of acute myocardial infarction
2000
Leukocyte trafficking and myocardial reperfusion injury in ICAM-1/P-selectin-knockout mice
2001
Induction of Monocyte Chemoattractant Protein-1 in the Small Veins of the Ischemic and Reperfused Canine Myocardium
1997
Pathophysiologically Relevant Concentrations of Tumor Necrosis Factor-α Promote Progressive Left Ventricular Dysfunction and Remodeling in Rats
1998
A Ras-Dependent Pathway Regulates RNA Polymerase II Phosphorylation in Cardiac Myocytes: Implications for Cardiac Hypertrophy
1998
Assessment of Myocardial Viability With 99m Tc Sestamibi in Patients Undergoing Cardiac Transplantation
1996
Cardiac progenitor cells from adult myocardium: Homing, differentiation, and fusion after infarction
2003 Standout
Cardiac Myocytes Produce Interleukin-6 in Culture and in Viable Border Zone of Reperfused Infarctions
1999
Telomerase reverse transcriptase promotes cardiac muscle cell proliferation, hypertrophy, and survival
2001
Hemodynamic changes in apolipoprotein E-knockout mice
2000