Citation Impact
Citing Papers
MutL traps MutS at a DNA mismatch
2015 StandoutNobel
Uracil DNA Glycosylase Activity Is Dispensable for Immunoglobulin Class Switch
2004 StandoutScienceNobel
A possible mechanism for exonuclease 1-independent eukaryotic mismatch repair
2009 StandoutNobel
MSH2–MSH6 stimulates DNA polymerase η, suggesting a role for A:T mutations in antibody genes
2005
DDB2 gene disruption leads to skin tumors and resistance to apoptosis after exposure to ultraviolet light but not a chemical carcinogen
2004
Protein roadblocks and helix discontinuities are barriers to the initiation of mismatch repair
2007 StandoutNobel
Activation-Induced Cytidine Deaminase-Dependent DNA Breaks in Class Switch Recombination Occur during G1 Phase of the Cell Cycle and Depend upon Mismatch Repair
2007
Saccharomyces cerevisiae MutLα Is a Mismatch Repair Endonuclease
2007 StandoutNobel
Regulatory Functions of the N-terminal Domain of the 70-kDa Subunit of Replication Protein A (RPA)
2008
hMSH3 and hMSH6 interact with PCNA and colocalize with it to replication foci
2001
DNA interrogation by the CRISPR RNA-guided endonuclease Cas9
2014 StandoutNatureNobel
Human Mismatch Repair
2005 StandoutNobel
Mutations within the hMLH1 and hPMS2 Subunits of the Human MutLα Mismatch Repair Factor Affect Its ATPase Activity, but Not Its Ability to Interact with hMutSα
2002
Mispair-specific Recruitment of the Mlh1-Pms1 Complex Identifies Repair Substrates of the Saccharomyces cerevisiae Msh2-Msh3 Complex
2014
Mechanisms in Eukaryotic Mismatch Repair
2006 StandoutNobel
The DNA-damage response in human biology and disease
2009 StandoutNature
Mismatch repair defects in cancer
2000
Transfer of the MSH2·MSH6 Complex from Proliferating Cell Nuclear Antigen to Mispaired Bases in DNA
2002
Programmable editing of a target base in genomic DNA without double-stranded DNA cleavage
2016 StandoutNature
Visualization of Mismatch Repair in Bacterial Cells
2001
Mutations in the MutSα interaction interface of MLH1 can abolish DNA mismatch repair
2006
Visualization of Eukaryotic DNA Mismatch Repair Reveals Distinct Recognition and Repair Intermediates
2011
The β Sliding Clamp Binds to Multiple Sites within MutL and MutS
2006 StandoutNobel
Single molecule studies of DNA mismatch repair
2014
Epigenetics in human disease and prospects for epigenetic therapy
2004 StandoutNature
Pms2 is a genetic enhancer of trinucleotide CAG{middle dot}CTG repeat somatic mosaicism: implications for the mechanism of triplet repeat expansion
2004
EXO1 and MSH6 Are High-Copy Suppressors of Conditional Mutations in the MSH2 Mismatch Repair Gene of Saccharomyces cerevisiae
2000
ATP hydrolysis-dependent formation of a dynamic ternary nucleoprotein complex with MutS and MutL
1999
Direct Visualization of Asymmetric Adenine Nucleotide-Induced Conformational Changes in MutLα
2008 StandoutNobel
Identification of a Second MutL DNA Mismatch Repair Complex (hPMS1 and hMLH1) in Human Epithelial Cells
2000
DNA mismatch repair: MutS structures bound to mismatches
2001
N-terminus of hMLH1 confers interaction of hMutL and hMutL with hMutS
2003
Interactions of Human Mismatch Repair Proteins MutSα and MutLα with Proteins of the ATR-Chk1 Pathway
2009 StandoutNobel
The MutSα-Proliferating Cell Nuclear Antigen Interaction in Human DNA Mismatch Repair
2008 StandoutNobel
Mismatch repair gene Msh2 modifies the timing of early disease in HdhQ111 striatum
2003
DNA Mismatch Repair in Eukaryotes and Bacteria
2010
PMS2-deficiency diminishes hypermutation of a λ1 transgene in young but not older mice
1999
Hydrolytic function of Exo1 in mammalian mismatch repair
2014 StandoutNobel
The endonuclease domain of MutL interacts with the β sliding clamp
2010
Direct association of Bloom's syndrome gene product with the human mismatch repair protein MLH1
2001
DNA mismatch repair and mutation avoidance pathways
2002
Endonucleolytic Function of MutLα in Human Mismatch Repair
2006 StandoutNobel
Mismatch repair proteins: key regulators of genetic recombination
2004
Programmable base editing of A•T to G•C in genomic DNA without DNA cleavage
2017 StandoutNature
Contribution of Human Mlh1 and Pms2 ATPase Activities to DNA Mismatch Repair
2002
The multifaceted mismatch-repair system
2006
MSH2 ATPase Domain Mutation Affects CTG•CAG Repeat Instability in Transgenic Mice
2009
The Involvement of DNA-Damage and -Repair Defects in Neurological Dysfunction
2008
Human Exonuclease I Is Required for 5′ and 3′ Mismatch Repair
2002 StandoutNobel
RPA2 Is a Direct Downstream Target for ATR to Regulate the S-phase Checkpoint
2006
Mutations affecting a putative MutLα endonuclease motif impact multiple mismatch repair functions
2007
Formation of a DNA Mismatch Repair Complex Mediated by ATP
2003
Structures of Human Exonuclease 1 DNA Complexes Suggest a Unified Mechanism for Nuclease Family
2011 StandoutNobel
DNA mismatch repair proteins promote apoptosis and suppress tumorigenesis in response to UVB irradiation: an in vivo study
2004
Eukaryotic mismatch repair: an update
1998
Functional Interaction of Proliferating Cell Nuclear Antigen with MSH2-MSH6 and MSH2-MSH3 Complexes
2000
Cellular processing of platinum anticancer drugs
2005 Standout
Bi-directional routing of DNA mismatch repair protein human exonuclease 1 to replication foci and DNA double strand breaks
2010
Complementary Roles for Exonuclease 1 and Flap Endonuclease 1 in Maintenance of Triplet Repeats
2010
Characterization of nuclease-dependent functions of Exo1p in Saccharomyces cerevisiae
2002
The Coordinated Functions of the E. coli MutS and MutL Proteins in Mismatch Repair
2003
Structure and function of mismatch repair proteins
2000
Replication errors: cha(lle)nging the genome
1998
Interaction of Escherichia coli MutS and MutL at a DNA Mismatch
2001
Biochemical Characterization of the Interaction between the Saccharomyces cerevisiae MSH2-MSH6 Complex and Mispaired Bases in DNA
1999
Evidence for sequential action of two ATPase active sites in yeast Msh2–Msh6
2002
The mechanism of mismatch repair and the functional analysis of mismatch repair defects in Lynch syndrome
2013
Steady-state Regulation of the Human DNA Mismatch Repair System
2000
Genome maintenance mechanisms for preventing cancer
2001 StandoutNature
Repeat instability as the basis for human diseases and as a potential target for therapy
2010
DNA Mismatch Repair
2000
MSH-MLH complexes formed at a DNA mismatch are disrupted by the PCNA sliding clamp
2001
MutLα and Proliferating Cell Nuclear Antigen Share Binding Sites on MutSβ
2010 StandoutNobel
The N Terminus of Saccharomyces cerevisiae Msh6 Is an Unstructured Tether to PCNA
2007
The base excision repair pathway
1995
Functional interactions and signaling properties of mammalian DNA mismatch repair proteins
2001
PARP-1 enhances the mismatch-dependence of 5′-directed excision in human mismatch repair in vitro
2011 StandoutNobel
Characterization of the Interactome of the Human MutL Homologues MLH1, PMS1, and PMS2
2006
High-mobility group box 1 protein (HMGB1): nuclear weapon in the immune arsenal
2005 Standout
Human DNA mismatch repair in vitro operates independently of methylation status at CpG sites
2001
DNA methyltransferase Dnmt1 and mismatch repair
2004
Proliferating cell nuclear antigen and Msh2p-Msh6p interact to form an active mispair recognition complex
2000
Schizosaccharomyces pombe exo1 is involved in the same mismatch repair pathway as msh2 and pms1
1998
Mechanisms of tolerance to DNA damaging therapeutic drugs
2001
Analysis of yeast MSH2-MSH6 suggests that the initiation of mismatch repair can be separated into discrete steps
2000
DNA Repair in Mammalian Cells
2009
Functions of MutLα, Replication Protein A (RPA), and HMGB1 in 5′-Directed Mismatch Repair
2009 StandoutNobel
Mismatch Repair in Human Nuclear Extracts
2002
Visualizing one-dimensional diffusion of eukaryotic DNA repair factors along a chromatin lattice
2010
Mechanisms of trinucleotide repeat instability during human development
2010
Nucleotide Excision Repair
2005 StandoutNobel
A Defined Human System That Supports Bidirectional Mismatch-Provoked Excision
2004 StandoutNobel
Sequential and Synergistic Modification of Human RPA Stimulates Chromosomal DNA Repair
2007
Pathological assessment of mismatch repair gene variants in Lynch syndrome: Past, present, and future
2012
Mechanisms and functions of DNA mismatch repair
2007
Mechanism of 5′-Directed Excision in Human Mismatch Repair
2003 StandoutNobel
DNA mismatch repair: Molecular mechanism, cancer, and ageing
2008
Mammalian DNA mismatch repair protects cells from UVB-induced DNA damage by facilitating apoptosis and p53 activation
2003
Mismatch Recognition and Uracil Excision Provide Complementary Paths to Both Ig Switching and the A/T-Focused Phase of Somatic Mutation
2004
Analysis of Interactions Between Mismatch Repair Initiation Factors and the Replication Processivity Factor PCNA
2005
PCNA-MutS -mediated binding of MutL to replicative DNA with mismatched bases to induce apoptosis in human cells
2005
Surveillance and Processing of Foreign DNA by the Escherichia coli CRISPR-Cas System
2015 StandoutNobel
PCNA function in the activation and strand direction of MutLα endonuclease in mismatch repair
2010 StandoutNobel
Mammalian DNA Mismatch Repair
1999
Circadian clock disruption improves the efficacy of chemotherapy through p73-mediated apoptosis
2011 StandoutNobel
DNA MISMATCH REPAIR AND GENETIC INSTABILITY
2000
DNA MISMATCH REPAIR
2005
Isolation and Characterization of New Proliferating Cell Nuclear Antigen (POL30) Mutator Mutants That Are Defective in DNA Mismatch Repair
2002
The puzzle of PCNA's many partners
2000
Quality Control by DNA Repair
1999 StandoutScienceNobel
Single-molecule imaging reveals target-search mechanisms during DNA mismatch repair
2012
Tea polyphenol (-)-epigallocatechin-3-gallate inhibits DNA methyltransferase and reactivates methylation-silenced genes in cancer cell lines.
2003
Saccharomyces cerevisiaeMsh2p and Msh6p ATPase Activities Are Both Required during Mismatch Repair
1998
ATP-independent diffusion of double-stranded RNA binding proteins
2012 StandoutNobel
Eukaryotic DNA mismatch repair
1999
DNA Mismatch Repair: Functions and Mechanisms
2005 StandoutNobel
A Mutation of the Yeast Gene Encoding PCNA Destabilizes Both Microsatellite and Minisatellite DNA Sequences
1999
DNA Mismatch Repair: Molecular Mechanisms and Biological Function
2003
Interactions of Exo1p with components of MutLα in Saccharomyces cerevisiae
2001
Physical Interaction between Replication Protein A (RPA) and MRN: Involvement of RPA2 Phosphorylation and the N-Terminus of RPA1
2009
PMS2 endonuclease activity has distinct biological functions and is essential for genome maintenance
2010 StandoutNobel
Control of skin cancer by the circadian rhythm
2011 StandoutNobel
cis -Diammine(pyridine)chloroplatinum(II), a monofunctional platinum(II) antitumor agent: Uptake, structure, function, and prospects
2008 StandoutNobel
In Vitro Analysis of the Role of Replication Protein A (RPA) and RPA Phosphorylation in ATR-mediated Checkpoint Signaling
2012 StandoutNobel
Replication protein A: directing traffic at the intersection of replication and repair
2010
exo1-Dependent Mutator Mutations: Model System for Studying Functional Interactions in Mismatch Repair
2001
Functional specificity of MutL homologs in yeast: Evidence for three Mlh1-based heterocomplexes with distinct roles during meiosis in recombination and mismatch correction
1999
Differential regulation of S-region hypermutation and class-switch recombination by noncanonical functions of uracil DNA glycosylase
2014 StandoutNobel
Cloning and characterization of a functional human homolog of Escherichia coli endonuclease III
1997 StandoutNobel
Mismatch Recognition-Coupled Stabilization of Msh2-Msh6 in an ATP-Bound State at the Initiation of DNA Repair
2003
Saccharomyces cerevisiae pol30 (Proliferating Cell Nuclear Antigen) Mutations Impair Replication Fidelity and Mismatch Repair
1999
DNA cleavage in immunoglobulin somatic hypermutation depends onde novoprotein synthesis but not on uracil DNA glycosylase
2005 StandoutNobel
Human PMS2 deficiency is associated with impaired immunoglobulin class switch recombination
2008
Enzymatic Processing of Radiation-Induced Free Radical Damage in DNA
1998
Human exonuclease 1 and BLM helicase interact to resect DNA and initiate DNA repair
2008 StandoutNobel
Extrahelical (CAG)/(CTG) triplet repeat elements support proliferating cell nuclear antigen loading and MutLα endonuclease activation
2013 StandoutNobel
High rate of CAD gene amplification in human cells deficient in MLH1 or MSH6
2001 StandoutNobel
hMutSβ Is Required for the Recognition and Uncoupling of Psoralen Interstrand Cross-Links In Vitro
2002
Direct Cellular Responses to Platinum-Induced DNA Damage
2007
Interaction of mismatch repair protein PMS2 and the p53-related transcription factor p73 in apoptosis response to cisplatin
2003
Circadian control of XPA and excision repair of cisplatin-DNA damage by cryptochrome and HERC2 ubiquitin ligase
2010 StandoutNobel
Mutator phenotypes of yeast strains heterozygous for mutations in the MSH 2 gene
1999
APE1 is dispensable for S-region cleavage but required for its repair in class switch recombination
2014 StandoutNobel
Msh2 ATPase Activity Is Essential for Somatic Hypermutation at A-T Basepairs and for Efficient Class Switch Recombination
2003
Repair of DNA–polypeptide crosslinks by human excision nuclease
2006 StandoutNobel
DNA Polymerase η Contributes to Strand Bias of Mutations of A versus T in Immunoglobulin Genes
2005
Works of Liya Gu being referenced
Mismatch Repair Processing of Carcinogen-DNA Adducts Triggers Apoptosis
1999
Evidence That Nucleosomes Inhibit Mismatch Repair in Eukaryotic Cells
2009
Differential Requirement for Proliferating Cell Nuclear Antigen in 5′ and 3′ Nick-directed Excision in Human Mismatch Repair
2004
Evidence for Involvement of HMGB1 Protein in Human DNA Mismatch Repair
2004
Incision-dependent and error-free repair of (CAG)n/(CTG)n hairpins in human cell extracts
2009
Nick-dependent and -independent Processing of Large DNA Loops in Human Cells
2003
Reconstitution of 5′-Directed Human Mismatch Repair in a Purified System
2005
Regulation of Replication Protein A Functions in DNA Mismatch Repair by Phosphorylation
2006
Bi-directional Processing of DNA Loops by Mismatch Repair-dependent and -independent Pathways in Human Cells
2003
Drosophila RrplcomplementsE.coli xth nfomutants: protection against both oxidative and alkylation-induced DNA damage
1993
Genetic and epigenetic modification of mismatch repair genes hMSH2 and hMLH1 in sporadic breast cancer with microsatellite instability
2002
Deficiency of a novel mismatch repair activity in a bladder tumor cell line
2002
ATP-dependent interaction of human mismatch repair proteins and dual role of PCNA in mismatch repair
1998
Distinct Nucleotide Binding/Hydrolysis Properties and Molar Ratio of MutSα and MutSβ Determine Their Differential Mismatch Binding Activities
2009
Mismatch Recognition Protein MutSβ Does Not Hijack (CAG) Hairpin Repair in Vitro
2009
Involvement of DNA mismatch repair in folate deficiency-induced apoptosis☆
2002
Mismatch repair deficiency in hematological malignancies with microsatellite instability
2002
hMRE11 deficiency leads to microsatellite instability and defective DNA mismatch repair
2005
Partial Reconstitution of Human DNA Mismatch Repair In Vitro: Characterization of the Role of Human Replication Protein A
2002
Single amino acid changes alter the repair specificity of Drosophila Rrp1. Isolation of mutants deficient in repair of oxidative DNA damage.
1994