Citation Impact
Citing Papers
Potent CRISPR-Cas9 inhibitors from Staphylococcus genomes
2020 StandoutNobel
Rewritable multi-event analog recording in bacterial and mammalian cells
2018 Science
DNA capture by a CRISPR-Cas9–guided adenine base editor
2020 StandoutScienceNobel
beditor : A Computational Workflow for Designing Libraries of Guide RNAs for CRISPR-Mediated Base Editing
2019
CRISPR–Cas9 Structures and Mechanisms
2017 StandoutNobel
Minimal PAM specificity of a highly similar SpCas9 ortholog
2018
Machine learning predicts new anti-CRISPR proteins
2020 StandoutNobel
Unconstrained genome targeting with near-PAMless engineered CRISPR-Cas9 variants
2020 Science
Origin of Antibiotics and Antibiotic Resistance, and Their Impacts on Drug Development: A Narrative Review
2023 Standout
Computational Stabilization of a Non‐Heme Iron Enzyme Enables Efficient Evolution of New Function
2024 StandoutNobel
Expanded base editing in rice and wheat using a Cas9-adenosine deaminase fusion
2018
CRISPR-Pass: Gene Rescue of Nonsense Mutations Using Adenine Base Editors
2019
Nucleoside-modified VEGFC mRNA induces organ-specific lymphatic growth and reverses experimental lymphedema
2021 StandoutNobel
A CRISPR-based base-editing screen for the functional assessment of BRCA1 variants
2019
Engineering of high-precision base editors for site-specific single nucleotide replacement
2019
The promise and challenge of therapeutic genome editing
2020 StandoutNatureNobel
Introduction of pathogenic mutations into the mouse Psen1 gene by Base Editor and Target-AID
2018
Structural basis for AcrVA4 inhibition of specific CRISPR-Cas12a
2019 StandoutNobel
Cas9-NG Greatly Expands the Targeting Scope of the Genome-Editing Toolkit by Recognizing NG and Other Atypical PAMs in Rice
2019
Engineering precision nanoparticles for drug delivery
2020 Standout
Improving cytidine and adenine base editors by expression optimization and ancestral reconstruction
2018
Phage-assisted evolution of an adenine base editor with improved Cas domain compatibility and activity
2020 StandoutNobel
Functional Genetic Variants Revealed by Massively Parallel Precise Genome Editing
2018
Study the Features of 57 Confirmed CRISPR Loci in 38 Strains of Staphylococcus aureus
2018
A scoutRNA Is Required for Some Type V CRISPR-Cas Systems
2020 StandoutNobel
A panel of eGFP reporters for single base editing by APOBEC-Cas9 editosome complexes
2019
Precise therapeutic gene correction by a simple nuclease-induced double-stranded break
2019 Nature
Genome-Editing Technologies: Principles and Applications
2016
Prediction of the sequence-specific cleavage activity of Cas9 variants
2020
An APOBEC3A-Cas9 base editor with minimized bystander and off-target activities
2018
CRISPR/Cas-Mediated Base Editing: Technical Considerations and Practical Applications
2019
Applications of genome editing technology in the targeted therapy of human diseases: mechanisms, advances and prospects
2020 Standout
Continuous evolution of base editors with expanded target compatibility and improved activity
2019
Applications of CRISPR-Cas Enzymes in Cancer Therapeutics and Detection
2018 StandoutNobel
Optimized base editors enable efficient editing in cells, organoids and mice
2018
Continuous evolution of Bacillus thuringiensis toxins overcomes insect resistance
2016 Nature
The road to fully programmable protein catalysis
2022 StandoutNatureNobel
Programmable RNA-Guided RNA Effector Proteins Built from Human Parts
2019
Efficient base editing in methylated regions with a human APOBEC3A-Cas9 fusion
2018
Programmable base editing of A•T to G•C in genomic DNA without DNA cleavage
2017 StandoutNature
Chemical Biology Approaches to Genome Editing: Understanding, Controlling, and Delivering Programmable Nucleases
2016
Adenine base editing in mouse embryos and an adult mouse model of Duchenne muscular dystrophy
2018
Base editing: precision chemistry on the genome and transcriptome of living cells
2018
Circularly permuted and PAM-modified Cas9 variants broaden the targeting scope of base editors
2019
Highly Parallel Profiling of Cas9 Variant Specificity
2020
Continuous directed evolution of aminoacyl-tRNA synthetases
2017
Enzyme engineering: reaching the maximal catalytic efficiency peak
2017
Genome editing in plants by engineered CRISPR–Cas9 recognizing NG PAM
2018
Web-based design and analysis tools for CRISPR base editing
2018
Search-and-replace genome editing without double-strand breaks or donor DNA
2019 StandoutNature
Genome editing with CRISPR–Cas nucleases, base editors, transposases and prime editors
2020 Standout
Rational designs of in vivo CRISPR-Cas delivery systems
2019
Deciphering Off-Target Effects in CRISPR-Cas9 through Accelerated Molecular Dynamics
2019 StandoutNobel
Bridge helix arginines play a critical role in Cas9 sensitivity to mismatches
2020 StandoutNobel
Adeno-associated virus vector as a platform for gene therapy delivery
2019 Standout
DNA-binding-domain fusions enhance the targeting range and precision of Cas9
2015
Genome-wide profiling of adenine base editor specificity by EndoV-seq
2019
Expanding the genome-targeting scope and the site selectivity of high-precision base editors
2020
Applications of CRISPR technologies in research and beyond
2016 StandoutNobel
The next generation of CRISPR–Cas technologies and applications
2019
Broad-spectrum enzymatic inhibition of CRISPR-Cas12a
2019 StandoutNobel
Evaluation and minimization of Cas9-independent off-target DNA editing by cytosine base editors
2020
A Cas9 with PAM recognition for adenine dinucleotides
2020
Improving Plant Genome Editing with High-Fidelity xCas9 and Non-canonical PAM-Targeting Cas9-NG
2019
Chemistry of Class 1 CRISPR-Cas effectors: Binding, editing, and regulation
2020 StandoutNobel
Engineering of monosized lipid-coated mesoporous silica nanoparticles for CRISPR delivery
2020 StandoutNobel
Directed evolution of CRISPR-Cas9 to increase its specificity
2018
An engineered ScCas9 with broad PAM range and high specificity and activity
2020
Increasing Cytosine Base Editing Scope and Efficiency With Engineered Cas9-PmCDA1 Fusions and the Modified sgRNA in Rice
2019
Genome Editing with mRNA Encoding ZFN, TALEN, and Cas9
2019
Development of hRad51–Cas9 nickase fusions that mediate HDR without double-stranded breaks
2019
A Compact, High-Accuracy Cas9 with a Dinucleotide PAM for In Vivo Genome Editing
2018
Gut microbiota in human metabolic health and disease
2020 Standout
Continuous evolution of SpCas9 variants compatible with non-G PAMs
2020
Massively parallel kinetic profiling of natural and engineered CRISPR nucleases
2020 StandoutNobel
High-throughput analysis of the activities of xCas9, SpCas9-NG and SpCas9 at matched and mismatched target sequences in human cells
2020
Development and Application of Base Editors
2019
Cu and Cu-Based Nanoparticles: Synthesis and Applications in Catalysis
2016 Standout
Restoration of Motor Function through Delayed Intraspinal Delivery of Human IL-10-Encoding Nucleoside-Modified mRNA after Spinal Cord Injury
2023 StandoutNobel
CRISPR-Cas-Based Antimicrobials: Design, Challenges, and Bacterial Mechanisms of Resistance
2023
Improved base editor for efficient editing in GC contexts in rabbits with an optimized AID‐Cas9 fusion
2019
Conditional Recruitment to a DNA-Bound CRISPR–Cas Complex Using a Colocalization-Dependent Protein Switch
2020 StandoutNobel
CRISPR-CasΦ from huge phages is a hypercompact genome editor
2020 StandoutScienceNobel
Analysis and minimization of cellular RNA editing by DNA adenine base editors
2019
Diagnosing COVID-19: The Disease and Tools for Detection
2020 Standout
MagnEdit—interacting factors that recruit DNA-editing enzymes to single base targets
2020
Aerobic Copper-Catalyzed Organic Reactions
2013 Standout
Evaluating and Enhancing Target Specificity of Gene-Editing Nucleases and Deaminases
2019
A Phage-Assisted Continuous Selection Approach for Deep Mutational Scanning of Protein–Protein Interactions
2019
Cas9 interrogates DNA in discrete steps modulated by mismatches and supercoiling
2020 StandoutNobel
Editing the microbiome the CRISPR way
2019
Targeted gene knock-in by homology-directed genome editing using Cas9 ribonucleoprotein and AAV donor delivery
2017 StandoutNobel
Clustered Regularly Interspaced Short Palindromic Repeats/Cas9-Mediated Lateral Flow Nucleic Acid Assay
2020
CRISPR-Cas guides the future of genetic engineering
2018 StandoutScienceNobel
Material solutions for delivery of CRISPR/Cas-based genome editing tools: Current status and future outlook
2019
Expanding the CRISPR Toolbox in P. patens Using SpCas9-NG Variant and Application for Gene and Base Editing in Solanaceae Crops
2020
CRISPR-Cas in Streptococcus pyogenes
2019 StandoutNobel
Functionally diverse type V CRISPR-Cas systems
2018 Science
Sharpening the Scissors: Mechanistic Details of CRISPR/Cas9 Improve Functional Understanding and Inspire Future Research
2018
CRISPR-Cas12a exploits R-loop asymmetry to form double-strand breaks
2020 StandoutNobel
Copper-catalyzed highly efficient aerobic oxidative synthesis of imines from alcohols and amines
2012
Accurate proteome-wide missense variant effect prediction with AlphaMissense
2023 StandoutScienceNobel
Copper oxide as efficient catalyst for oxidative dehydrogenation of alcohols with air
2015
Works of Liwei Chen being referenced
Evolved Cas9 variants with broad PAM compatibility and high DNA specificity
2018 Nature
Continuous directed evolution of DNA-binding proteins to improve TALEN specificity
2015
A Copper(II) Triflate‐Catalyzed Tandem Friedel–Crafts Alkylation/Cyclization Process towards Dihydroindenes
2011