Citation Impact
Citing Papers
Nuclear Lamin-A Scales with Tissue Stiffness and Enhances Matrix-Directed Differentiation
2013 StandoutScience
Rationally Designed High-Affinity 2-Amino-6-halopurine Heat Shock Protein 90 Inhibitors That Exhibit Potent Antitumor Activity
2007
Treatment of kidney cancer
2009 StandoutNobel
Design, Synthesis, and Biological Evaluation of Hydroquinone Derivatives of 17-Amino-17-demethoxygeldanamycin as Potent, Water-Soluble Inhibitors of Hsp90
2006
The Concept of Synthetic Lethality in the Context of Anticancer Therapy
2005 StandoutNobel
EttA regulates translation by binding the ribosomal E site and restricting ribosome-tRNA dynamics
2014 StandoutNobel
Open Babel: An open chemical toolbox
2011 Standout
Epidermal growth factor receptor mutations in lung cancer
2007 Standout
Structural Analysis of E. coli hsp90 Reveals Dramatic Nucleotide-Dependent Conformational Rearrangements
2006
Automated ligand fitting by core-fragment fitting and extension into density
2006
Direct Visualization of Asymmetric Adenine Nucleotide-Induced Conformational Changes in MutLα
2008 StandoutNobel
Functional in vivo imaging of cysteine cathepsin activity in murine model of inflammation
2010
The resurgence of platinum-based cancer chemotherapy
2007 Standout
Modulation of oxidative stress as an anticancer strategy
2013 Standout
Treatment of Obesity with Celastrol
2015 Standout
Far-red to near infrared analyte-responsive fluorescent probes based on organic fluorophore platforms for fluorescence imaging
2012 Standout
rDock: A Fast, Versatile and Open Source Program for Docking Ligands to Proteins and Nucleic Acids
2014
New approaches to molecular cancer therapeutics
2006
Heat shock protein 90: The cancer chaperone
2007
Molecular Dynamics Simulation for All
2018 Standout
HSP90 and the chaperoning of cancer
2005 Standout
Blind docking of pharmaceutically relevant compounds using RosettaLigand
2009 StandoutNobel
Crystal structure of an Hsp90–nucleotide–p23/Sba1 closed chaperone complex
2006 Nature
Anticancer activities of histone deacetylase inhibitors
2006 Standout
Targeting the phosphoinositide 3-kinase pathway in cancer
2009 Standout
MAP kinase signalling pathways in cancer
2007 Standout
Protein and ligand preparation: parameters, protocols, and influence on virtual screening enrichments
2013 Standout
Cysteine cathepsins: From structure, function and regulation to new frontiers
2011
Extracellular matrix structure
2015 Standout
Structure-based drug screening for G-protein-coupled receptors
2012 StandoutNobel
The ABC-F protein EttA gates ribosome entry into the translation elongation cycle
2014 StandoutNobel
Molecular chaperones in protein folding and proteostasis
2011 StandoutNature
Targeting the Hsp90 Chaperone: Synthesis of Novel Resorcylic Acid Macrolactone Inhibitors of Hsp90
2010
RACK1 Competes with HSP90 for Binding to HIF-1α and Is Required for O2-Independent and HSP90 Inhibitor-Induced Degradation of HIF-1α
2007 StandoutNobel
Targeting the Raf-MEK-ERK mitogen-activated protein kinase cascade for the treatment of cancer
2007 Standout
Twists and Turns of the Cation-dependent Mannose 6-Phosphate Receptor
2002
Mitochondrial Membrane Permeabilization in Cell Death
2007 Standout
Alternate States of Proteins Revealed by Detailed Energy Landscape Mapping
2010 StandoutNobel
Transforming fragments into candidates: small becomes big in medicinal chemistry
2009
Interpretation of ensembles created by multiple iterative rebuilding of macromolecular models
2007
Targeting multiple signal transduction pathways through inhibition of Hsp90
2004
RosettaLigand Docking with Full Ligand and Receptor Flexibility
2008 StandoutNobel
Features and development of Coot
2010 Standout
Dihydroxylphenyl amides as inhibitors of the Hsp90 molecular chaperone
2008
Paul Ehrlich's magic bullet concept: 100 years of progress
2008 Standout
Targeting the glycans of glycoproteins: a novel paradigm for antiviral therapy
2007
Inhibitors of the HSP90 Molecular Chaperone: Current Status
2006
PHENIX: a comprehensive Python-based system for macromolecular structure solution
2010 Standout
Synthesis and Microcontact Printing of Dual End‐Functionalized Mucin‐like Glycopolymers for Microarray Applications
2009 StandoutNobel
Drugging the Cancer Chaperone HSP90
2007
A Gibbs free energy correlation for automated docking of carbohydrates
2007
Targeting chaperones in transformed systems – a focus on Hsp90 and cancer
2006
HIV-1 Neutralization Profile and Plant-Based Recombinant Expression of Actinohivin, an Env Glycan-Specific Lectin Devoid of T-Cell Mitogenic Activity
2010 StandoutNobel
Principles of Cancer Therapy: Oncogene and Non-oncogene Addiction
2009 Standout
Click Chemistry for Drug Development and Diverse Chemical–Biology Applications
2013 Standout
Heat-shock protein 90 inhibitors as novel cancer chemotherapeutics – an update
2005
Fluorine in Pharmaceutical Industry: Fluorine-Containing Drugs Introduced to the Market in the Last Decade (2001–2011)
2013 Standout
Identification of Potent Water Soluble Purine-Scaffold Inhibitors of the Heat Shock Protein 90
2005
Fluorine and Fluorinated Motifs in the Design and Application of Bioisosteres for Drug Design
2018 Standout
Development of synthetic routes to macrocyclic compounds based on the HSP90 inhibitor radicicol
2006
The Medicinal Chemist’s Toolbox: An Analysis of Reactions Used in the Pursuit of Drug Candidates
2011 Standout
Structure, Function, and Evolution of Bacterial ATP-Binding Cassette Systems
2008
The Sonogashira Reaction: A Booming Methodology in Synthetic Organic Chemistry
2007 Standout
Signals for Sorting of Transmembrane Proteins to Endosomes and Lysosomes
2003 Standout
Adaptive and Maladaptive Cardiorespiratory Responses to Continuous and Intermittent Hypoxia Mediated by Hypoxia-Inducible Factors 1 and 2
2012 StandoutNobel
Orally Active Purine-Based Inhibitors of the Heat Shock Protein 90
2005
Diverse, High-Quality Test Set for the Validation of Protein−Ligand Docking Performance
2007
Force Field Optimization Guided by Small Molecule Crystal Lattice Data Enables Consistent Sub-Angstrom Protein–Ligand Docking
2021 StandoutNobel
Structural Isosteres of Phosphate Groups in the Protein Data Bank
2017
Anti-Markovnikov hydroarylation of styrenes catalyzed by an in situ generated ruthenium complex
2008
Small Molecule Modulators of Protein–Protein Interactions: Selected Case Studies
2014
Fragment-Based Drug Discovery Applied to Hsp90. Discovery of Two Lead Series with High Ligand Efficiency
2010
Ruthenium(II)-Catalyzed C–H Bond Activation and Functionalization
2012 Standout
LigPlot+: Multiple Ligand–Protein Interaction Diagrams for Drug Discovery
2011 Standout
HSP90 and its inhibitors (Review)
2010
Benchmarking Sets for Molecular Docking
2006
Impact of Natural Products on Developing New Anti-Cancer Agents
2009 Standout
Evaluation of 8-Arylsulfanyl, 8-Arylsulfoxyl, and 8-Arylsulfonyl Adenine Derivatives as Inhibitors of the Heat Shock Protein 90
2005
Shielded Hydrogen Bonds as Structural Determinants of Binding Kinetics: Application in Drug Design
2011
Applications of Palladium-Catalyzed C–N Cross-Coupling Reactions
2016 Standout
Native Folding of a Recombinant gpE1/gpE2 Heterodimer Vaccine Antigen from a Precursor Protein Fused with Fc IgG
2016 StandoutNobel
Natural Products as Sources of New Drugs from 1981 to 2014
2016 Standout
Mechanism by which the lectin actinohivin blocks HIV infection of target cells
2009 StandoutNobel
Visible‐Light Photocatalysis: Does It Make a Difference in Organic Synthesis?
2018 Standout
From 2000 to Mid-2010: A Fruitful Decade for the Synthesis of Pyrazoles
2011 Standout
Carbohydrate Chips for Studying High-Throughput Carbohydrate−Protein Interactions
2004
Discovery of Benzisoxazoles as Potent Inhibitors of Chaperone Heat Shock Protein 90
2008
Mannose-Specific Plant Lectins from the Amaryllidaceae Family Qualify as Efficient Microbicides for Prevention of Human Immunodeficiency Virus Infection
2004
Works of Lisa Wright being referenced
4-Amino derivatives of the Hsp90 inhibitor CCT018159
2006
Structure-Activity Relationships in Purine-Based Inhibitor Binding to HSP90 Isoforms
2004
Structure-based discovery of a new class of Hsp90 inhibitors
2005
Adenine derived inhibitors of the molecular chaperone HSP90—SAR explained through multiple X-ray structures
2003
Structure of the native (unligated) mannose-specific bulb lectin from Scilla campanulata (bluebell) at 1.7 Å resolution
1999
The Structure of the Oligopeptide-binding Protein, AppA, from Bacillus subtilis in Complex with a Nonapeptide
2004
Insights into carbohydrate recognition by Narcissus pseudonarcissus lectin: the crystal structure at 2 Å resolution in complex with α1-3 mannobiose 1 1Edited by J. Thornton
1999
3-(5-chloro-2,4-dihydroxyphenyl)-Pyrazole-4-carboxamides as inhibitors of the Hsp90 molecular chaperone
2005
Novel, Potent Small-Molecule Inhibitors of the Molecular Chaperone Hsp90 Discovered through Structure-Based Design
2005
Structure of a Cys25→Ser mutant of human cathepsin S
2002