Citation Impact
Citing Papers
Neurotoxic protein expression reveals connections between the circadian clock and mating behavior in Drosophila
2006 StandoutNobel
p62/SQSTM1 forms protein aggregates degraded by autophagy and has a protective effect on huntingtin-induced cell death
2005 Standout
Oxidative Stress
2017 Standout
TFEB Links Autophagy to Lysosomal Biogenesis
2011 StandoutScience
Untangling the ErbB signalling network
2001 Standout
Protein misfolding disorders and macroautophagy
2010
Cellular Inclusion Bodies of Mutant Huntingtin Exon 1 Obscure Small Fibrillar Aggregate Species
2012 StandoutNobel
Apoptosis in neurodegenerative disorders
2000
Apoptosis in the nervous system
2000 StandoutNature
The Ubiquitin Proteasome System in Neurodegenerative Diseases
2003 StandoutNobel
Molecular Bases for Circadian Clocks
1999 Standout
Regulation of cell death: the calcium–apoptosis link
2003 Standout
The Blood-Brain Barrier in Health and Chronic Neurodegenerative Disorders
2008 Standout
Loss of normal huntingtin function: new developments in Huntington's disease research
2001
Modular regulatory principles of large non-coding RNAs
2012 StandoutNature
The role of autophagy in neurodegenerative disease
2013 Standout
Molecular genetics: Unmasking polyglutamine triggers in neurodegenerative disease
2000
Huntington's disease
2007 Standout
Soluble protein oligomers in neurodegeneration: lessons from the Alzheimer's amyloid β-peptide
2007 Standout
Inhibition of mTOR induces autophagy and reduces toxicity of polyglutamine expansions in fly and mouse models of Huntington disease
2004 Standout
Inhibition of caspase-1 slows disease progression in a mouse model of Huntington's disease
1999 Nature
A cell-based screen for drugs to treat Huntington's disease
2004
Inclusion body formation reduces levels of mutant huntingtin and the risk of neuronal death
2004 StandoutNature
Down Syndrome Fibroblast Model of Alzheimer-Related Endosome Pathology
2008
Mutant Huntingtin Promotes the Fibrillogenesis of Wild-type Huntingtin
2003
Function and Regulation of CREB Family Transcription Factors in the Nervous System
2002 Standout
Autophagy fights disease through cellular self-digestion
2008 StandoutNature
Huntington’s disease: degradation of mutant huntingtin by autophagy
2008
Cell Death
2004 Standout
Endoplasmic reticulum stress: cell life and death decisions
2005 Standout
BCL-2 family members and the mitochondria in apoptosis
1999 Standout
Suppression of basal autophagy in neural cells causes neurodegenerative disease in mice
2006 StandoutNature
Electron microscopic immunocytochemical evidence that the calmodulin-dependent cyclic nucleotide phosphodiesterase is localized predominantly at postsynaptic sites in the rat brain
1991
DARPP‐32, a phosphoprotein enriched in dopaminoceptive neurons bearing dopamine D1 receptors: DIstribution in the cerebral cortex of the newborn and adult rhesus monkey
1990
Chloroquine-Induced Neuronal Cell Death Is p53 and Bcl-2 Family-Dependent But Caspase-Independent
2001
Protein aggregation and neurodegenerative disease
2004 Standout
Apoptosis in Huntington's disease
2003
Glial and neuronal expression of polyglutamine proteins induce behavioral changes and aggregate formation in Drosophila
2004
Cell death triggered by polyglutamine-expanded huntingtin in a neuronal cell line is associated with degradation of CREB-binding protein
2003
Huntingtin Is Present in the Nucleus, Interacts with the Transcriptional Corepressor C-terminal Binding Protein, and Represses Transcription
2002
The neural basis of human error processing: Reinforcement learning, dopamine, and the error-related negativity.
2002 Standout
Mitochondrial Membrane Permeabilization in Cell Death
2007 Standout
Proteasomal inhibition leads to formation of ubiquitin/α‐synuclein‐immunoreactive inclusions in PC12 cells
2001
Polyglutamine expansions cause decreased CRE-mediated transcription and early gene expression changes prior to cell death in an inducible cell model of Huntington's disease
2001
NEW EMBO MEMBERS' REVIEW: The ErbB signaling network: receptor heterodimerization in development and cancer
2000 Standout
The PtdIns(3,4)P2 phosphatase INPP4A is a suppressor of excitotoxic neuronal death
2010 StandoutNatureNobel
Polyglutamine aggregates stimulate ER stress signals and caspase-12 activation
2002
Polyglutamine Expansion, Protein Aggregation, Proteasome Activity, and Neural Survival
2002
The Evf-2 noncoding RNA is transcribed from the Dlx-5/6 ultraconserved region and functions as a Dlx-2 transcriptional coactivator
2006
Autophagy in cell death: an innocent convict?
2005 Standout
Repertoires of Autophagy in the Pathogenesis of Ocular Diseases
2015 Standout
AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1
2011 Standout
Aggresomes Formed by α-Synuclein and Synphilin-1 Are Cytoprotective
2004
Autophagy: process and function
2007 Standout
Cleavage of Bax is mediated by caspase‐dependent or ‐independent calpain activation in dopaminergic neuronal cells: protective role of Bcl‐2
2001
Evolution and Functions of Long Noncoding RNAs
2009 Standout
Mitochondrial membrane depolarization and the selective death of dopaminergic neurons by rotenone: protective effect of coenzyme Q10
2005
Huntington’s disease: how does huntingtin, an anti-apoptotic protein, become toxic?
2004
Selective Neuronal Degeneration in Huntington's Disease
2006
Long noncoding RNAs: functional surprises from the RNA world
2009 Standout
Long non-coding RNAs: insights into functions
2009 Standout
Pathways towards and away from Alzheimer's disease
2004 StandoutNature
The Neuropathology of Huntington’s Disease
2014
Autophagy regulates the processing of amino terminal huntingtin fragments
2003
Uropathic Observations in Mice Expressing a Constitutively Active Point Mutation in the 5-HT3AReceptor Subunit
2004 StandoutNobel
Can autophagy protect against neurodegeneration caused by aggregate-prone proteins?
2004
Pro-caspase-8 Is Predominantly Localized in Mitochondria and Released into Cytoplasm upon Apoptotic Stimulation
2001
Aggregates in neurodegenerative disease: crowds and power?
1999
The Deacetylase HDAC6 Regulates Aggresome Formation and Cell Viability in Response to Misfolded Protein Stress
2003 Standout
Repurposing the NRF2 Activator Dimethyl Fumarate as Therapy Against Synucleinopathy in Parkinson's Disease
2016
Huntingtin aggregates may not predict neuronal death in Huntington's disease
1999
Gain of Function Mutants: Ion Channels and G Protein-Coupled Receptors
2000
Huntingtin Expression Stimulates Endosomal–Lysosomal Activity, Endosome Tubulation, and Autophagy
2000
Diagnosis and Treatment of Parkinson Disease
2020 Standout
Tauroursodeoxycholic acid, a bile acid, is neuroprotective in a transgenic animal model of Huntington's disease
2002
Huntington aggregates may not predict neuronal death in Huntington's disease.
1999
Cyclic nucleotide phosphodiesterases: functional implications of multiple isoforms
1995 Standout
A Role for α-Synuclein in the Regulation of Dopamine Biosynthesis
2002
Caspase 3-cleaved N-terminal fragments of wild-type and mutant huntingtin are present in normal and Huntington's disease brains, associate with membranes, and undergo calpain-dependent proteolysis
2001
Tau Suppression in a Neurodegenerative Mouse Model Improves Memory Function
2005 StandoutScience
Lentiviral-Mediated Delivery of Mutant Huntingtin in the Striatum of Rats Induces a Selective Neuropathology Modulated by Polyglutamine Repeat Size, Huntingtin Expression Levels, and Protein Length
2002
Proteasomal-Dependent Aggregate Reversal and Absence of Cell Death in a Conditional Mouse Model of Huntington's Disease
2001
Reactive Oxygen Species (ROS)-Based Nanomedicine
2019 Standout
Levodopa‐induced dyskinesia in Parkinson disease: Current and evolving concepts
2018
Impaired Degradation of Mutant α-Synuclein by Chaperone-Mediated Autophagy
2004 StandoutScience
Transcriptional dysregulation in Huntington’s disease
2000
Activation of Membrane-associated Procaspase-3 Is Regulated by Bcl-2
1999
Two Alternatively Spliced Transcripts from the Drosophila period Gene Rescue Rhythms Having Different Molecular and Behavioral Characteristics
1998
A role for alpha-synuclein in the regulation of dopamine biosynthesis.
2002
ErbB3 is required for normal cerebellar and cardiac development: a comparison with ErbB2- and heregulin-deficient mice
1997
Expanded CAG repeats in exon 1 of the Huntington's disease gene stimulate dopamine-mediated striatal neuron autophagy and degeneration
2001
Perinuclear localization of huntingtin as a consequence of its binding to microtubules through an interaction with β-tubulin: relevance to Huntington's disease
2002
Tissue-Specific Proteolysis of Huntingtin (htt) in Human Brain: Evidence of Enhanced Levels of N- and C-Terminal htt Fragments in Huntington's Disease Striatum
2001
Morphogenic potentials of D2, D3, and D4 dopamine receptors revealed in transfected neuronal cell lines.
1994
Autophagy-mediated clearance of huntingtin aggregates triggered by the insulin-signaling pathway
2006
Mechanisms of Endocytosis
2009 Standout
Dopamine Receptors: From Structure to Function
1998 Standout
Regulation of Mammalian Autophagy in Physiology and Pathophysiology
2010 Standout
Metals in Neurobiology: Probing Their Chemistry and Biology with Molecular Imaging
2008 Standout
The Role of Atg Proteins in Autophagosome Formation
2011 StandoutNobel
Quantitative neuropathological changes in presymptomatic Huntington's disease
2001
Autophagy in Health and Disease: A Double-Edged Sword
2004 StandoutScience
Works of Lisa Won being referenced
Forskolin and dopamine D1 receptor activation increase Huntingtin's association with endosomes in immortalized neuronal cells of striatal origin
1999
Altered responses to potassium in cerebellar neurons from weaver heterozygote mice
1998
Preferential resistance of dopaminergic neurons to glutathione depletion in a reconstituted nigrostriatal system
2000
Enhanced histamine H2 excitation of striatal cholinergic interneurons in l-DOPA-induced dyskinesia
2015
Immortalization of embryonic mesencephalic dopaminergic neurons by somatic cell fusion
1991
Glial-derived neurotrophic factor (GDNF) induced morphological differentiation of an immortalized monoclonal hybrid dopaminergic cell line of mesencephalic neuronal origin
1996
Mutant Huntingtin Expression in Clonal Striatal Cells: Dissociation of Inclusion Formation and Neuronal Survival by Caspase Inhibition
1999
Immortalized murine striatal neuronal cell lines expressing dopamine receptors and cholinergic properties
1995
Specific modulation of dopamine expression in neuronal hybrid cells by primary cells from different brain regions.
1992
Analysis of huntingtin-associated protein 1 in mouse brain and immortalized striatal neurons
1999
Analysis of huntingtin‐associated protein 1 in mouse brain and immortalized striatal neurons
1999
Correlated light and electron microscopic study of dopaminergic neurons and their synaptic junctions with DARPP‐32‐containing cells in three‐dimensional reaggregate tissue culture
1989