Standout Papers
- Aberrant Splicing and Altered Spatial Expression Patterns in fruitless Mutants of Drosophila melanogaster (2000)
- Control of Male Sexual Behavior and Sexual Orientation in Drosophila by the fruitless Gene (1996)
- Molecular Genetic Dissection of the Sex-Specific and Vital Functions of the Drosophila melanogaster Sex Determination Gene fruitless (2001)
- Behavioral and neurobiological implications of sex‐determining factors inDrosophila (1994)
Citation Impact
Citing Papers
Neurotoxic protein expression reveals connections between the circadian clock and mating behavior in Drosophila
2006 StandoutNobel
Distinct mechanisms regulate hemocyte chemotaxis during development and wound healing in Drosophila melanogaster
2006
Vascular endothelial growth factor can signal through platelet-derived growth factor receptors
2007
Transposition-Driven Genomic Heterogeneity in the Drosophila Brain
2013 StandoutScienceNobel
Placental growth factor reconstitutes hematopoiesis by recruiting VEGFR1+ stem cells from bone-marrow microenvironment
2002
DOUBLESEX GENE EXPRESSION IN THE CENTRAL NERVOUS SYSTEM OF DROSOPHILA MELANOGASTER
2002 StandoutNobel
In the beginning is the end: regulation of poly(A) addition and removal during early development
1990
RNA-directed DNA methylation
2000
The PDGF family: four gene products form five dimeric isoforms
2004
Functional dissection of the drosophila mushroom bodies by selective feminization ofagenetically defined subcompartments
1995
A kinder, gentler genetic analysis of behavior: dissection gives way to modulation
1997
Differentiation of a male-specific muscle in Drosophila melanogaster does not require the sex-determining genes doublesex or intersex.
1992
Common themes in the function of transcription and splicing enhancers
1997
On the Role of RNA Amplification in dsRNA-Triggered Gene Silencing
2001 StandoutNobel
Topology of the human and mouse m6A RNA methylomes revealed by m6A-seq
2012 StandoutNature
A Novel Nuclear Human Poly(A) Polymerase (PAP), PAPγ
2001
RBMY, a probable human spermatogenesis factor, and other hnRNP G proteins interact with Tra2beta and affect splicing
2000
Crystal Structures of the Bacillus stearothermophilus CCA-Adding Enzyme and Its Complexes with ATP or CTP
2002 StandoutNobel
Crystal structure of mammalian poly(A) polymerase in complex with an analog of ATP
2000
Alternative isoform regulation in human tissue transcriptomes
2008 StandoutNature
Male-specific fruitless specifies the neural substrates of Drosophila courtship behaviour
2005 StandoutNatureNobel
The Regulation of the Drosophila Gene Reveals a Function for in Translational Control
1997
The Drosophila takeout gene is regulated by the somatic sex-determination pathway and affects male courtship behavior
2002
Mushroom bodies are not required for courtship behavior by normal and sexually mosaic Drosophila
2002
Specific interactions between proteins implicated in splice site selection and regulated alternative splicing
1993
A splicing enhancer complex controls alternative splicing of doublesex pre-mRNA
1993
Role of platelet-derived growth factors in physiology and medicine
2008 Standout
Analysis of the functional specificity of RS domains invivo
1998
Wound repair and regeneration
2008 StandoutNature
The regulation of sex determination and sexually dimorphic differentiation in Drosophila
1993
Thicker Than Blood
2003
Molecular characterization of a peripheral receptor for cannabinoids
1993 StandoutNature
Hematopoiesis: An Evolving Paradigm for Stem Cell Biology
2008 Standout
Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells
2001 StandoutNature
Sexual behavior mutants revisited: molecular and cellular basis of Drosophila mating
1999
Quality control of mRNA 3′-end processing is linked to the nuclear exosome
2001 StandoutNatureNobel
Genes Expressed in Neurons of Adult Male Drosophila
1997 StandoutNobel
Fruitlessis in the Regulatory Pathway by Which EctopicMini-WhiteandTransformerInduce Bisexual Courtship inDrosophila
2000
Sorting out the complexity of SR protein functions
2000
The telomere terminal transferase of tetrahymena is a ribonucleoprotein enzyme with two kinds of primer specificity
1987 StandoutNobel
Formation of the male-specific muscle in female Drosophila by ectopic fruitless expression
2000
New reproductive anomalies in fruitless‐mutant Drosophila males: Extreme lengthening of mating durations and infertility correlated with defective serotonergic innervation of reproductive organs
2001 StandoutNobel
Exon Recognition in Vertebrate Splicing
1995
Molecular neurogenetics of sexual differentiation and behaviour
1999
Courtship Behavior of Brain Mosaics in Drosophila
1998
Two isoforms of Serpent containing either one or two GATA zinc fingers have different roles in Drosophila haematopoiesis
2002
Eater, a Transmembrane Protein Mediating Phagocytosis of Bacterial Pathogens in Drosophila
2005 StandoutNobel
Ganglion-specific splicing of TRPV1 underlies infrared sensation in vampire bats
2011 StandoutNatureNobel
Analysis of Temperature-Sensitive Mutants Reveals New Genes Involved in the Courtship Song of Drosophila
1998 StandoutNobel
Sequence specificity of the human mRNA N6-adenosine methylasein vitro
1990 StandoutNobel
Neural Circuitry that Governs Drosophila Male Courtship Behavior
2005
Exon mutations uncouple 5′ splice site selection from U1 snRNA pairing
1990 StandoutNobel
Characterization of Drosophila fruitless‐gal4 transgenes reveals expression in male‐specific fruitless neurons and innervation of male reproductive structures
2004
Understanding alternative splicing: towards a cellular code
2005
Editing of glutamate receptor subunit B pre-mRNA in vitro by site-specific deamination of adenosine
1995 StandoutNatureNobel
Protein Phosphorylation Plays an Essential Role in the Regulation of Alternative Splicing and Sex Determination in Drosophila
1998
RNA polymerase II is an essential mRNA polyadenylation factor
1998 Nature
Median bundle neurons coordinate behaviours during Drosophila male courtship
2004 Nature
Identification of functional U1 snRNA-pre-mRNA complexes committed to spliceosome assembly and splicing
1989 StandoutNobel
Role of poly(ADP-ribose) formation in DNA repair
1992 StandoutNatureNobel
The Regulation of Splice-Site Selection, and Its Role in Human Disease
1997
Spatial, temporal, and sexually dimorphic expression patterns of thefruitless gene in theDrosophila central nervous system
2000 StandoutNobel
Activity‐dependent regulation of alternative splicing patterns in the rat brain
1999
Courtship and Other Behaviors Affected by a Heat-Sensitive, Molecularly Novel Mutation in the cacophony Calcium-Channel Gene of Drosophila
2002 StandoutNobel
Cross-Intron Bridging Interactions in the Yeast Commitment Complex Are Conserved in Mammals
1997 StandoutNobel
Posttranscriptional regulation of the heterochronic gene lin-14 by lin-4 mediates temporal pattern formation in C. elegans
1993 StandoutNobel
Genes expressed in the Drosophila head reveal a role for fat cells in sex-specific physiology
2002
A Newly Uncovered Phenotype Associated with the fruitless Gene of Drosophila melanogaster: Aggression-like Head Interactions Between Mutant Males
2000
fruitless Splicing Specifies Male Courtship Behavior in Drosophila
2005
Multiple EGFR ligands participate in guiding migrating border cells
2006
Activation of c-src neuron-specific splicing by an unusual RNA element in vivo and in vitro
1992
Sexual behaviour in Drosophila is irreversibly programmed during a critical period
1998
Polyadenylation factor CPSF-73 is the pre-mRNA 3'-end-processing endonuclease
2006 Nature
Primary structure and expression of bovine poly(A) polymerase
1991 Nature
Sex determination and differentiation in invertebrates: Drosophila and Caenorhabditis elegans
1992
Are Complex Behaviors Specified by Dedicated Regulatory Genes? Reasoning from Drosophila
2001 StandoutNobel
Courtship Anomalies Caused by doublesex Mutations in Drosophila melanogaster
1996 StandoutNobel
Complex Protein Interactions within the Human Polyadenylation Machinery Identify a Novel Component
2000
The PDGF/VEGF Receptor Controls Blood Cell Survival in Drosophila
2004
Molecular Architecture of the Human Pre-mRNA 3′ Processing Complex
2009 StandoutNobel
Natural Variation in a Neuropeptide Y Receptor Homolog Modifies Social Behavior and Food Response in C. elegans
1998
Point mutations in AAUAAA and the poly (A) addition site: effects on the accuracy and efficiency of cleavage and polyadenylationin vitro
1990
The protein Sex-lethal antagonizes the splicing factor U2AF to regulate alternative splicing of transformer pre-mRNA
1993 Nature
PVF2, a PDGF/VEGF‐like growth factor, induces hemocyte proliferation in Drosophila larvae
2002 StandoutNobel
Nuclear Reprogramming in Cells
2008 StandoutScienceNobel
GENETIC DISSECTION OF SEXUAL BEHAVIOR IN DROSOPHILA MELANOGASTER
1997
Kap104p: A Karyopherin Involved in the Nuclear Transport of Messenger RNA Binding Proteins
1996 StandoutScienceNobel
NAB2: a Yeast Nuclear Polyadenylated RNA-Binding Protein Essential for Cell Viability
1993
U1 snRNP targets an essential splicing factor, U2AF65, to the 3' splice site by a network of interactions spanning the exon.
1992
VIVE LA DIFFÉRENCE: Males vs Females in Flies vs Worms
1996
Identification of a Bidirectional Splicing Enhancer: Differential Involvement of SR Proteins in 5′ or 3′ Splice Site Activation
1999
Induction of cellular immunity by immunization with novel hybrid peptides complexed to heat shock protein 70
2000 StandoutNobel
The msl-2 dosage compensation gene of Drosophila encodes a putative DNA-binding protein whose expression is sex specifically regulated by Sex-lethal
1995
Conditional disruption of synaptic transmission induces male–male courtship behavior in Drosophila
2002
The Sex-lethal Early Splicing Pattern Uses a Default Mechanism Dependent on the Alternative 5′ Splice Sites
1997
Vascular Endothelial Growth Factor: Basic Science and Clinical Progress
2004 Standout
The muscle of Lawrence in Drosophila : A case of repeated evolutionary loss
1997 StandoutNobel
The Drosophila splicing regulator sex-lethal directly inhibits translation of male-specific-lethal 2 mRNA.
1998
The role of small nuclear ribonucleoprotein particles in pre-mRNA splicing
1987 Nature
Regulation of alternative pre-mRNA splicing by a novel repeated hexanucleotide element.
1994
The C. elegans pvf‐1 gene encodes a PDGF/VEGF‐like factor able to bind mammalian VEGF receptors and to induce angiogenesis
2006
Topical Vascular Endothelial Growth Factor Accelerates Diabetic Wound Healing through Increased Angiogenesis and by Mobilizing and Recruiting Bone Marrow-Derived Cells
2004
The mec-8 gene of C. elegans encodes a protein with two RNA recognition motifs and regulates alternative splicing of unc-52 transcripts
1996
Structure, function and evolution of sex-determining systems in Dipteran insects
2000
Sexual orientation in Drosophila is altered by the satori mutation in the sex-determination gene fruitless that encodes a zinc finger protein with a BTB domain.
1996
Formation of mRNA 3′ Ends in Eukaryotes: Mechanism, Regulation, and Interrelationships with Other Steps in mRNA Synthesis
1999
Multiple Distinct Splicing Enhancers in the Protein-Coding Sequences of a Constitutively Spliced Pre-mRNA
1999
Characterization of the multisubunit cleavage-polyadenylation specificity factor from calf thymus.
1992
S. cerevisiae U1 RNA is large and has limited primary sequence homology to metazoan U1 snRNA
1987 StandoutNobel
The Chemistry of Self-Splicing RNA and RNA Enzymes
1987 StandoutScienceNobel
PVF1, a PDGF/VEGF homolog, is sufficient to guide border cells and interacts genetically with Taiman
2003
The fruitless Gene Is Required for the Proper Formation of Axonal Tracts in the Embryonic Central Nervous System of Drosophila
2002
DNA sequences that mediate attenuation of transcription from the mouse protooncogene myc.
1989 StandoutNobel
Conserved Intron Elements Repress Splicing of a Neuron-Specific c-src Exon In Vitro
1997
Roles of PDGF in animal development
2003
ALTERNATIVE SPLICING OF PRE-mRNA: Developmental Consequences and Mechanisms of Regulation
1998
dissatisfaction , a gene involved in sex-specific behavior and neural development of Drosophila melanogaster
1997
Conditional Defect in mRNA 3′ End Processing Caused by a Mutation in the Gene for Poly(A) Polymerase
1992
The generally expressed hnRNP F is involved in a neural-specific pre-mRNA splicing event.
1995
Saccharomyces cerevisiae U1 small nuclear RNA secondary structure contains both universal and yeast-specific domains.
1990 StandoutNobel
Elements regulating an alternatively spliced exon of the rat fibronectin gene.
1993
COURTSHIP INDROSOPHILA
2000
Abnormalities of Male-Specific FRU Protein and Serotonin Expression in the CNS offruitlessMutants inDrosophila
2001 StandoutNobel
Identification and Functional Characterization of Neo-Poly(A) Polymerase, an RNA Processing Enzyme Overexpressed in Human Tumors
2001
Assembly of specific SR protein complexes on distinct regulatory elements of the Drosophila doublesex splicing enhancer.
1996
Targeted disruption of an essential vertebrate gene: ASF/SF2 is required for cell viability.
1996
Four factors are required for 3'-end cleavage of pre-mRNAs.
1989
Functional analysis of fruitless gene expression by transgenic manipulations of Drosophila courtship
2005 StandoutNobel
Cooperation of pre-mRNA sequence elements in splice site selection.
1992
Purification of the cleavage and polyadenylation factor involved in the 3'-processing of messenger RNA precursors.
1991
The Sex-lethal amino terminus mediates cooperative interactions in RNA binding and is essential for splicing regulation.
1994
Molecular cloning and analysis of DNA complementary to three mouse Mr = 68,000 heat shock protein mRNAs.
1986
Extended Reproductive Roles of the fruitless Gene in Drosophila melanogaster Revealed by Behavioral Analysis of New fru Mutants
1997 StandoutNobel
The Mating of a Fly
1994 StandoutScienceNobel
Analysis of the Doublesex Female Protein in Drosophila melanogaster: Role in Sexual Differentiation and Behavior and Dependence on Intersex
1999
Positive Control of Pre-mRNA Splicing in Vitro
1992 Science
TRANSCRIPTION TERMINATION AND THE REGULATION OF GENE EXPRESSION
1986
Defects in courtship and vision caused by amino acid substitutions in a putative RNA-binding protein encoded by the no-on-transient A (nonA) gene of Drosophila
1996
Protein structure prediction for the male-specific region of the human Y chromosome
2004 StandoutNobel
Some cis- and trans-acting mutants for splicing target pre-mRNA to the cytoplasm
1989 StandoutNobel
A splicing enhancer exhibits both constitutive and regulated activities.
1994
A multisubunit factor, CstF, is required for polyadenylation of mammalian pre-mRNAs.
1990
Drosophila : The Genetics of Innate Immune Recognition and Response
2004
The splicing factor U2AF35 mediates critical protein-protein interactions in constitutive and enhancer-dependent splicing.
1996
Mechanisms of Alternative Pre-Messenger RNA Splicing
2003 Standout
Mode of enzyme-bound poly(ADP-ribose) synthesis and histone modification by reconstituted poly(ADP-ribose) polymerase-DNA-cellulose complex.
1981
Genetic Feminization of Brain Structures and Changed Sexual Orientation in Male Drosophila
1995 Science
Sex-specific differentiation of a male-specific abdominal muscle, the Muscle of Lawrence, is abnormal in hydroxyurea-treated and in fruitless male flies
1995
The Neuron-Enriched Splicing Pattern of Drosophila erect wing Is Dependent on the Presence of ELAV Protein
2000
Conserved Intron Elements Repress Splicing of a Neuron-Specific c-src Exon In Vitro
1995
Works of Lisa Ryner being referenced
Regulation of Sex-Specific Selection of fruitless 5′ Splice Sites by transformer and transformer-2
1998
Sex in the '90s
1995
Developmental Control of Blood Cell Migration by the Drosophila VEGF Pathway
2002
Behavioral and neurobiological implications of sex‐determining factors inDrosophila
1994 StandoutNobel
Separation and characterization of a poly(A) polymerase and a cleavage/specificity factor required for pre-mRNA polyadenylation
1988
Control of Male Sexual Behavior and Sexual Orientation in Drosophila by the fruitless Gene
1996 StandoutNobel
Multiple Forms of Poly(A) Polymerases Purified from HeLa Cells Function in Specific mRNA 3′-End Formation
1989
Multiple forms of poly(A) polymerases purified from HeLa cells function in specific mRNA 3'-end formation.
1989
Autoregulation and multifunctionality among trans-acting factors that regulate alternative pre-mRNA processing.
1992
Requirements for accurate and efficient mRNA 3' end cleavage and polyadenylation of a simian virus 40 early pre-RNA in vitro.
1987
Molecular Genetic Dissection of the Sex-Specific and Vital Functions of the Drosophila melanogaster Sex Determination Gene fruitless
2001 StandoutNobel
Aberrant Splicing and Altered Spatial Expression Patterns in fruitless Mutants of Drosophila melanogaster
2000 StandoutNobel
Sequences Downstream of AAUAAA Signals Affect Pre-mRNA Cleavage and Polyadenylation In Vitro Both Directly and Indirectly
1989
RNA sequence containing hexanucleotide AAUAAA directs efficient mRNA polyadenylation in vitro.
1985
RNA Sequence Containing Hexanucleotide AAUAAA Directs Efficient mRNA Polyadenylation In Vitro
1985
Regulation of doublesex pre-mRNA processing occurs by 3'-splice site activation.
1991