Citation Impact
Citing Papers
Activation and Function of the MAPKs and Their Substrates, the MAPK-Activated Protein Kinases
2011 Standout
Global defects in collagen secretion in a Mia3/TANGO1 knockout mouse
2011
Signal integration in the endoplasmic reticulum unfolded protein response
2007 Standout
p300 Modulates ATF4 Stability and Transcriptional Activity Independently of Its Acetyltransferase Domain
2005
Genome-wide features of neuroendocrine regulation in Drosophila by the basic helix-loop-helix transcription factor DIMMED
2015 StandoutNobel
The GCN2‐ATF4 pathway is critical for tumour cell survival and proliferation in response to nutrient deprivation
2010
RIM1α and Interacting Proteins Involved in Presynaptic Plasticity Mediate Prepulse Inhibition and Additional Behaviors Linked to Schizophrenia
2010 StandoutNobel
Mechanisms, regulation and functions of the unfolded protein response
2020 Standout
Role of glutamate in schizophrenia: integrating excitatory avenues of research
2008
Signalling mediated by the endoplasmic reticulum stress transducer OASIS is involved in bone formation
2009
Integrated analysis of somatic mutations and focal copy-number changes identifies key genes and pathways in hepatocellular carcinoma
2012 Standout
Brown and beige fat: development, function and therapeutic potential
2013 Standout
Rheumatoid arthritis
2016 Standout
Cancer to bone: a fatal attraction
2011 Standout
From acute ER stress to physiological roles of the Unfolded Protein Response
2006
Smad transcription factors
2005 Standout
Altered ERK/MAPK signaling in the hippocampus of the mrsk2_KO mouse model of Coffin‐Lowry syndrome
2011
The Oxidative Stressor Arsenite Activates Vascular Endothelial Growth Factor mRNA Transcription by an ATF4-dependent Mechanism
2005
The unfolded protein response: controlling cell fate decisions under ER stress and beyond
2012 Standout
TGF-β1–induced migration of bone mesenchymal stem cells couples bone resorption with formation
2009 Standout
FIAT, the factor‐inhibiting ATF4‐mediated transcription, also represses the transcriptional activity of the bZIP factor FRA‐1
2010
Clock and ATF4 transcription system regulates drug resistance in human cancer cell lines
2007
Regulation of Translation Initiation in Eukaryotes: Mechanisms and Biological Targets
2009 Standout
Tumor Metastasis: Molecular Insights and Evolving Paradigms
2011 Standout
ATF4 regulates lipid metabolism and thermogenesis
2010
The mechanism of eukaryotic translation initiation and principles of its regulation
2010 Standout
Hippo Pathway in Organ Size Control, Tissue Homeostasis, and Cancer
2015 Standout
Osteoarthritis
2015 Standout
Indigenous Bacteria from the Gut Microbiota Regulate Host Serotonin Biosynthesis
2015 Standout
Maf promotes osteoblast differentiation in mice by mediating the age-related switch in mesenchymal cell differentiation
2010
Skeletal remodeling in health and disease
2007 Standout
Cooperative Interactions between Activating Transcription Factor 4 and Runx2/Cbfa1 Stimulate Osteoblast-specific Osteocalcin Gene Expression
2005
The RSK factors of activating the Ras/MAPK signaling cascade
2008
WNT signaling in bone homeostasis and disease: from human mutations to treatments
2013 Standout
From Krebs to clinic: glutamine metabolism to cancer therapy
2016 Standout
Control of Activating Transcription Factor 4 (ATF4) Persistence by Multisite Phosphorylation Impacts Cell Cycle Progression and Neurogenesis*
2010
Ubiquitin-dependent regulation of COPII coat size and function
2012 StandoutNatureNobel
Fibroblast growth factor signalling: from development to cancer
2010 Standout
Wnt/β-Catenin Signaling: Components, Mechanisms, and Diseases
2009 Standout
Endoplasmic Reticulum Stress and the Inflammatory Basis of Metabolic Disease
2010 Standout
Lrp5 Controls Bone Formation by Inhibiting Serotonin Synthesis in the Duodenum
2008
Leptin regulation of bone resorption by the sympathetic nervous system and CART
2005 Nature
Control of mRNA translation preserves endoplasmic reticulum function in beta cells and maintains glucose homeostasis
2005
p53 in health and disease
2007 Standout
Endocrine Regulation of Energy Metabolism by the Skeleton
2007 Standout
Building strong bones: molecular regulation of the osteoblast lineage
2011
Emerging Biological Principles of Metastasis
2017 Standout
Suppression of bone formation by osteoclastic expression of semaphorin 4D
2011 Standout
The many roles of histone deacetylases in development and physiology: implications for disease and therapy
2008 Standout
Cooperative interaction of Zhangfei and ATF4 in transactivation of the cyclic AMP response element
2005
Cell death and endoplasmic reticulum stress: disease relevance and therapeutic opportunities
2008 Standout
The gut microbiota — masters of host development and physiology
2013 Standout
AKT/PKB Signaling: Navigating the Network
2017 Standout
ATF4 mediation of NF1 functions in osteoblast reveals a nutritional basis for congenital skeletal dysplasiae
2006
Adipocyte differentiation from the inside out
2006 Standout
Repertoires of Autophagy in the Pathogenesis of Ocular Diseases
2015 Standout
Epigenetic modifications and human disease
2010 Standout
XBP1 Links ER Stress to Intestinal Inflammation and Confers Genetic Risk for Human Inflammatory Bowel Disease
2008 Standout
Histone Deacetylase 4 Controls Chondrocyte Hypertrophy during Skeletogenesis
2004
Histone deacetylase inhibitors and the promise of epigenetic (and more) treatments for cancer
2006 Standout
COPII and the regulation of protein sorting in mammals
2011 StandoutNobel
Metastatic colonization by circulating tumour cells
2016 StandoutNature
Gene array analysis of Wnt-regulated genes in C3H10T1/2 cells
2005
Induction of osteoclastogenesis and bone loss by human autoantibodies against citrullinated vimentin
2012
Mitosin/CENP-F as a Negative Regulator of Activating Transcription Factor-4
2005
SEC23-SEC31 the Interface Plays Critical Role for Export of Procollagen from the Endoplasmic Reticulum
2012 StandoutNobel
Clinical and molecular overview of inherited disorders resulting from epigenomic dysregulation
2009
Molecular mechanisms of mTOR-mediated translational control
2009 Standout
SATB2 Is a Multifunctional Determinant of Craniofacial Patterning and Osteoblast Differentiation
2006
Immunogenic cell death and DAMPs in cancer therapy
2012 Standout
The integrated stress response
2016 Standout
Proteoglycan 4 Expression Protects Against the Development of Osteoarthritis
2013
Glomerulocystic kidney disease in mice with a targeted inactivation of Wwtr1
2007
ATF4 is an oxidative stress–inducible, prodeath transcription factor in neurons in vitro and in vivo
2008
Activating transcription factor 4
2007
Bright Side of Lignin Depolymerization: Toward New Platform Chemicals
2018 Standout
Regulation of basal cellular physiology by the homeostatic unfolded protein response
2010
ATF4 promotes bone angiogenesis by increasing vegf expression and release in the bone environment
2013
CHOP induces activating transcription factor 5 (ATF5) to trigger apoptosis in response to perturbations in protein homeostasis
2013
The Unfolded Protein Response: From Stress Pathway to Homeostatic Regulation
2011 StandoutScience
THE MAMMALIAN UNFOLDED PROTEIN RESPONSE
2005 Standout
Combretastatin A-4 Analogue: A Dual-Targeting and Tubulin Inhibitor Containing Antitumor Pt(IV) Moiety with a Unique Mode of Action
2016
Regulation and function of the RSK family of protein kinases
2011
Targeting the UPR transcription factor XBP1 protects against Huntington's disease through the regulation of FoxO1 and autophagy
2012
Reinitiation involving upstream ORFs regulates ATF4 mRNA translation in mammalian cells
2004
Sudestada1, a Drosophila ribosomal prolyl-hydroxylase required for mRNA translation, cell homeostasis, and organ growth
2014 StandoutNobel
Regulation of bone formation and remodeling by G-protein-coupled receptor 48
2009
p53 functions as a negative regulator of osteoblastogenesis, osteoblast-dependent osteoclastogenesis, and bone remodeling
2005
Vascular Calcification
2006 Standout
Fibroblast Growth Factor Receptor 3 Associates with and Tyrosine Phosphorylates p90 RSK2, Leading to RSK2 Activation That Mediates Hematopoietic Transformation
2009
Palaeoproteomic evidence identifies archaic hominins associated with the Châtelperronian at the Grotte du Renne
2016 StandoutNobel
PERK‐eIF2α‐ATF4‐CHOP Signaling Contributes to TNFα‐Induced Vascular Calcification
2013
Ribosomal protein RPL41 induces rapid degradation of ATF4, a transcription factor critical for tumour cell survival in stress
2011
Works of Lingzhen Li being referenced
Vimentin Inhibits ATF4-mediated Osteocalcin Transcription and Osteoblast Differentiation
2009
No genetic association between polymorphisms in the kainate-type glutamate receptor gene, GRIK4, and schizophrenia in the Chinese population
2008
ATF4 Is a Substrate of RSK2 and an Essential Regulator of Osteoblast Biology
2004
Atf4 regulates chondrocyte proliferation and differentiation during endochondral ossification by activating Ihh transcription
2009
Design and Synthesis of Cyclopropylamide Analogues of Combretastatin-A4 as Novel Microtubule-Stabilizing Agents
2013