Standout Papers
Citation Impact
Citing Papers
Microscale technologies for tissue engineering and biology
2006
Fate Mapping Analysis Reveals That Adult Microglia Derive from Primitive Macrophages
2010 StandoutScience
A low level of reactive oxygen species selects for primitive hematopoietic stem cells that may reside in the low-oxygenic niche
2007
Wnt-inhibitory factor 1 dysregulation of the bone marrow niche exhausts hematopoietic stem cells
2011
Heterogeneity and hierarchy within the most primitive hematopoietic stem cell compartment
2010
In vivo imaging of hydrogen peroxide production in a murine tumor model with a chemoselective bioluminescent reporter
2010 StandoutNobel
Extracellular matrix protein tenascin-C is required in the bone marrow microenvironment primed for hematopoietic regeneration
2012
Recurrent Fusion of TMPRSS2 and ETS Transcription Factor Genes in Prostate Cancer
2005 StandoutScience
Strategy for Dual-Analyte Luciferin Imaging: In Vivo Bioluminescence Detection of Hydrogen Peroxide and Caspase Activity in a Murine Model of Acute Inflammation
2013 StandoutNobel
Reconstituting Organ-Level Lung Functions on a Chip
2010 StandoutScience
Osteoclasts promote the formation of hematopoietic stem cell niches in the bone marrow
2012
Hypoxia-Inducible Factors in Physiology and Medicine
2012 StandoutNobel
Wnt Signaling in the Niche Enforces Hematopoietic Stem Cell Quiescence and Is Necessary to Preserve Self-Renewal In Vivo
2008
Noncanonical Wnt Signaling Maintains Hematopoietic Stem Cells in the Niche
2012
Analysis of histone 2B-GFP retention reveals slowly cycling hematopoietic stem cells
2008
Effect of Mixing of Metal Cations on the Topology of Metal Oxide Networks
2007
Maintenance of the Hematopoietic Stem Cell Pool by CXCL12-CXCR4 Chemokine Signaling in Bone Marrow Stromal Cell Niches
2006 Standout
Resolving the Controversy about N-Cadherin and Hematopoietic Stem Cells
2010
Hematopoietic stem cell fate is established by the Notch–Runx pathway
2005
A Microenvironment-Induced Myeloproliferative Syndrome Caused by Retinoic Acid Receptor γ Deficiency
2007
Epithelial-mesenchymal transition and its implications for fibrosis
2003 Standout
Self-Renewing Osteoprogenitors in Bone Marrow Sinusoids Can Organize a Hematopoietic Microenvironment
2007 Standout
Critical Role of Thrombopoietin in Maintaining Adult Quiescent Hematopoietic Stem Cells
2007
CXCL12 in early mesenchymal progenitors is required for haematopoietic stem-cell maintenance
2013 Nature
Rb Regulates Interactions between Hematopoietic Stem Cells and Their Bone Marrow Microenvironment
2007
Hematopoietic Stem Cells
2006
Cancer to bone: a fatal attraction
2011 Standout
The microenvironment of the embryonic neural stem cell: Lessons from adult niches?
2007
Self-renewal and solid tumor stem cells
2004
Targeting the glycans of gp120: a novel approach aimed at the Achilles heel of HIV
2005
The landscape of mRNA nanomedicine
2022
Engraftment and Reconstitution of Hematopoiesis Is Dependent on VEGFR2-Mediated Regeneration of Sinusoidal Endothelial Cells
2009
Thrombopoietin/MPL Signaling Regulates Hematopoietic Stem Cell Quiescence and Interaction with the Osteoblastic Niche
2007
Hematopoietic Stem Cells Reversibly Switch from Dormancy to Self-Renewal during Homeostasis and Repair
2008
Control of blood cell homeostasis in Drosophila larvae by the posterior signalling centre
2007 Nature
Wound repair and regeneration
2008 StandoutNature
Metabolic Regulation of Hematopoietic Stem Cells in the Hypoxic Niche
2011 StandoutNobel
Identification of tendon stem/progenitor cells and the role of the extracellular matrix in their niche
2007 Standout
N-Cadherin Expression Level Distinguishes Reserved versus Primed States of Hematopoietic Stem Cells
2008
Osteoblastic cells regulate the haematopoietic stem cell niche
2003 StandoutNature
PTEN maintains haematopoietic stem cells and acts in lineage choice and leukaemia prevention
2006 Nature
Socializing with the Neighbors
2004 Standout
Asymmetric cortical and nuclear localizations of WRM-1/β-catenin during asymmetric cell division in C. elegans
2005
GAS6/AXL Axis Regulates Prostate Cancer Invasion, Proliferation, and Survival in the Bone Marrow Niche
2010
Hematopoiesis: An Evolving Paradigm for Stem Cell Biology
2008 Standout
The bone marrow at the crossroads of blood and immunity
2011
In vitro and in vivo expansion of hematopoietic stem cells
2004
Tie2/Angiopoietin-1 Signaling Regulates Hematopoietic Stem Cell Quiescence in the Bone Marrow Niche
2004 Standout
Nonmyelinating Schwann Cells Maintain Hematopoietic Stem Cell Hibernation in the Bone Marrow Niche
2011
Live-animal tracking of individual haematopoietic stem/progenitor cells in their niche
2008 Nature
The bone marrow niche for haematopoietic stem cells
2014 StandoutNature
Integrins and bone metastasis: Integrating tumor cell and stromal cell interactions
2010
Skeletal remodeling in health and disease
2007 Standout
Haematopoietic stem cells do not asymmetrically segregate chromosomes or retain BrdU
2007 Nature
Cadherin-Based Adhesion Is a Potential Target for Niche Manipulation to Protect Hematopoietic Stem Cells in Adult Bone Marrow
2010
Human prostate cancer metastases target the hematopoietic stem cell niche to establish footholds in mouse bone marrow
2011
Stem Cells and Niches: Mechanisms That Promote Stem Cell Maintenance throughout Life
2008
Intrinsic Immunity Shapes Viral Resistance of Stem Cells
2017 StandoutNobel
Ferreting out stem cells from their niches
2011
SLAM Family Receptors Distinguish Hematopoietic Stem and Progenitor Cells and Reveal Endothelial Niches for Stem Cells
2005 Standout
Uncertainty in the niches that maintain haematopoietic stem cells
2008
The Role of the Wnt-Signaling Antagonist DKK1 in the Development of Osteolytic Lesions in Multiple Myeloma
2003
Cytokine signals modulated via lipid rafts mimic niche signals and induce hibernation in hematopoietic stem cells
2006
Regulation of SDF-1 (CXCL12) production by osteoblasts; a possible mechanism for stem cell homing
2005
Building strong bones: molecular regulation of the osteoblast lineage
2011
Mesenchymal and haematopoietic stem cells form a unique bone marrow niche
2010 StandoutNature
Detection of functional haematopoietic stem cell niche using real-time imaging
2008 Nature
Hematopoietic Stem Cells Do Not Depend on N-Cadherin to Regulate Their Maintenance
2009
The stem cell niche: theme and variations
2004
The stem-cell niche as an entity of action
2006 Nature
Microenvironmental niches in the bone marrow required for B-cell development
2006
A Hedgehog- and Antennapedia-dependent niche maintains Drosophila haematopoietic precursors
2007 Nature
Bone-marrow haematopoietic-stem-cell niches
2006
The Placenta Is a Niche for Hematopoietic Stem Cells
2005
c-Myc controls the balance between hematopoietic stem cell self-renewal and differentiation
2004
Endothelial Cells Are Essential for the Self-Renewal and Repopulation of Notch-Dependent Hematopoietic Stem Cells
2010
Regional Localization within the Bone Marrow Influences the Functional Capacity of Human HSCs
2013
Hypoxia mediates low cell-cycle activity and increases the proportion of long-term–reconstituting hematopoietic stem cells during in vitro culture
2010
Bone progenitor dysfunction induces myelodysplasia and secondary leukaemia
2010 Nature
Chiral Molecular Magnets: Synthesis, Structure, and Magnetic Behavior of the Series [M(L ‐tart)] (M = MnII, FeII, CoII, NiII; L ‐tart = (2R,3R)‐(+)‐tartrate)
2006
Bone metastasis: the importance of the neighbourhood
2016
Targeting the glycans of glycoproteins: a novel paradigm for antiviral therapy
2007
Endochondral ossification is required for haematopoietic stem-cell niche formation
2008 Nature
Integration of Notch and Wnt signaling in hematopoietic stem cell maintenance
2005
Haematopoietic stem cell release is regulated by circadian oscillations
2008 Nature
Matrix-Embedded Osteocytes Regulate Mobilization of Hematopoietic Stem/Progenitor Cells
2013
Angiocrine factors from Akt-activated endothelial cells balance self-renewal and differentiation of haematopoietic stem cells
2010
Wnt signalling in stem cells and cancer
2005 StandoutNature
Hematopoietic Stem Cell Trafficking
2007
Lack of Evidence that Hematopoietic Stem Cells Depend on N-Cadherin-Mediated Adhesion to Osteoblasts for Their Maintenance
2007
Arteriolar niches maintain haematopoietic stem cell quiescence
2013 Nature
Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche
2009 StandoutNature
Quantitative imaging of haematopoietic stem and progenitor cell localization and hypoxic status in the bone marrow microenvironment
2013
Pleiotrophin Regulates the Retention and Self-Renewal of Hematopoietic Stem Cells in the Bone Marrow Vascular Niche
2012
Maintaining Hematopoietic Stem Cells in the Vascular Niche
2006
Identification of stem cells in small intestine and colon by marker gene Lgr5
2007 StandoutNature
BMP signaling inhibits intestinal stem cell self-renewal through suppression of Wnt–β-catenin signaling
2004
Stem cell engraftment at the endosteal niche is specified by the calcium-sensing receptor
2005 Nature
Matrix Elasticity Directs Stem Cell Lineage Specification
2006 Standout
Signals from the Sympathetic Nervous System Regulate Hematopoietic Stem Cell Egress from Bone Marrow
2006
Development of Virus-Like Particle Technology from Small Highly Symmetric to Large Complex Virus-Like Particle Structures
2013 Standout
Cellular Niches Controlling B Lymphocyte Behavior within Bone Marrow during Development
2004
“Mesenchymal” Stem Cells in Human Bone Marrow (Skeletal Stem Cells): A Critical Discussion of Their Nature, Identity, and Significance in Incurable Skeletal Disease
2010
Novel Role of NADPH Oxidase in Angiogenesis and Stem/Progenitor Cell Function
2009
Nuclear Reprogramming in Cells
2008 StandoutScienceNobel
Convergence of Wnt, ß-Catenin, and Cadherin Pathways
2004 StandoutScience
Long-term renewal of hair follicles from clonogenic multipotent stem cells
2005
The journey of developing hematopoietic stem cells
2006
Strontium can increase some osteoblasts without increasing hematopoietic stem cells
2007
Osteopontin, a key component of the hematopoietic stem cell niche and regulator of primitive hematopoietic progenitor cells
2005
Isolating gene-corrected stem cells without drug selection
2005 StandoutNobel
Targeted and Equally Distributed Delivery of mRNA to Organs with Pentaerythritol-Based One-Component Ionizable Amphiphilic Janus Dendrimers
2023 StandoutNobel
Bone marrow dysfunction in mice lacking the cytokine receptor gp130 in endothelial cells
2005
Osteopontin is a hematopoietic stem cell niche component that negatively regulates stem cell pool size
2005
PDGFRα and CD51 mark human Nestin+ sphere-forming mesenchymal stem cells capable of hematopoietic progenitor cell expansion
2013
Rational HIV Immunogen Design to Target Specific Germline B Cell Receptors
2013 StandoutScienceNobel
Osteoblastic N-cadherin is not required for microenvironmental support and regulation of hematopoietic stem and progenitor cells
2012
Osteoblasts support B-lymphocyte commitment and differentiation from hematopoietic stem cells
2007
A human colon cancer cell capable of initiating tumour growth in immunodeficient mice
2006 StandoutNature
The relationship between bone, hemopoietic stem cells, and vasculature
2011
Programmed assembly of 3-dimensional microtissues with defined cellular connectivity
2009 StandoutNobel
A Perspective on Cancer Cell Metastasis
2011 StandoutScience
Hematopoiesis is severely altered in mice with an induced osteoblast deficiency
2004
Chiral Cyanide-Bridged MnIIMnIII Ferrimagnets, [MnII(HL)(H2O)][MnIII(CN)6]·2H2O (L = S- or R-1,2-diaminopropane): Syntheses, Structures, and Magnetic Behaviors
2006 StandoutNobel
Distribution of hematopoietic stem cells in the bone marrow according to regional hypoxia
2007
Bone Morphogenetic Protein Signaling Inhibits Hair Follicle Anagen Induction by Restricting Epithelial Stem/Progenitor Cell Activation and Expansion
2006
Notch signaling controls germline stem cell niche formation in theDrosophilaovary
2007
Loss of Cxcl12/Sdf-1 in adult mice decreases the quiescent state of hematopoietic stem/progenitor cells and alters the pattern of hematopoietic regeneration after myelosuppression
2010
Differential impact of Ink4a and Arf on hematopoietic stem cells and their bone marrow microenvironment in Bmi1-deficient mice
2006
TSC–mTOR maintains quiescence and function of hematopoietic stem cells by repressing mitochondrial biogenesis and reactive oxygen species
2008
Cellular Analyses of the Mitotic Region in theCaenorhabditis elegansAdult Germ Line
2006
Control of stem cell self-renewal and differentiation by the heterochronic genes and the cellular asymmetry machinery in Caenorhabditis elegans
2015 StandoutNobel
Soluble Frizzled-Related Protein 1 Is Estrogen Inducible in Bone Marrow Stromal Cells and Suppresses the Earliest Events in Lymphopoiesis
2008
Defective osteogenesis of the stromal stem cells predisposes CD18-null mice to osteoporosis
2005
Broad Neutralization of Human Immunodeficiency Virus Type 1 (HIV-1) Elicited from Human Rhinoviruses That Display the HIV-1 gp41 ELDKWA Epitope
2009
Electrochemical Glucose Biosensors
2007 Standout
Osteoblastic regulation of B lymphopoiesis is mediated by G s α-dependent signaling pathways
2008
The Bone Marrow Vascular Niche: Home of HSC Differentiation and Mobilization
2005
Adhesion molecules in the stem cell niche – more than just staying in shape?
2010
Design of a hyperstable 60-subunit protein icosahedron
2016 StandoutNatureNobel
The amazing osteocyte
2010 Standout
N-cadherin in osteolineage cells is not required for maintenance of hematopoietic stem cells
2012
Current View: Intestinal Stem Cells and Signaling
2008
Epithelial-mesenchymal transition and its implications for fibrosis
2003 Standout
Direct transformation from amorphous to crystalline calcium phosphate facilitated by motif-programmed artificial proteins
2008
Mechanism by which the lectin actinohivin blocks HIV infection of target cells
2009 StandoutNobel
Structural insights into key sites of vulnerability on HIV ‐1 Env and influenza HA
2012
Transcriptomes of germinal zones of human and mouse fetal neocortex suggest a role of extracellular matrix in progenitor self-renewal
2012 StandoutNobel
Signaling in stem cell niches: lessons from theDrosophilagermline
2005
Polysialic acid governs T-cell development by regulating progenitor access to the thymus
2009 StandoutNobel
Rational Design of Bisphosphonate Lipid-like Materials for mRNA Delivery to the Bone Microenvironment
2022 StandoutNobel
Quantum dot/antibody conjugates for in vivo cytometric imaging in mice
2015 StandoutNobel
Chemotherapy triggers HIF-1–dependent glutathione synthesis and copper chelation that induces the breast cancer stem cell phenotype
2015 StandoutNobel
STEM CELL NICHE: Structure and Function
2005
Modular Design of Domain Assembly in Porous Coordination Polymer Crystals via Reactivity-Directed Crystallization Process
2012 StandoutNobel
Coexistence of Quiescent and Active Adult Stem Cells in Mammals
2010 StandoutScience
Combinatorial Gata2 and Sca1 expression defines hematopoietic stem cells in the bone marrow niche
2006
Bone marrow macrophages maintain hematopoietic stem cell (HSC) niches and their depletion mobilizes HSCs
2010
The Essential Functions of Adipo-osteogenic Progenitors as the Hematopoietic Stem and Progenitor Cell Niche
2010
Self-catalyzed growth of S layers via an amorphous-to-crystalline transition limited by folding kinetics
2010 StandoutNobel
Knockdown of N-cadherin suppresses the long-term engraftment of hematopoietic stem cells
2010
Palaeoproteomic evidence identifies archaic hominins associated with the Châtelperronian at the Grotte du Renne
2016 StandoutNobel
Elicitation of structure-specific antibodies by epitope scaffolds
2010 StandoutNobel
Stem Cells and Their Niches
2006 Science
Works of Ling Ye being referenced
Identification of the haematopoietic stem cell niche and control of the niche size
2003 StandoutNature
Modified HIV envelope proteins with enhanced binding to neutralizing monoclonal antibodies
2004
Deletion of Dentin Matrix Protein-1 Leads to a Partial Failure of Maturation of Predentin into Dentin, Hypomineralization, and Expanded Cavities of Pulp and Root Canal during Postnatal Tooth Development
2004
Mechanical Loading Stimulates Dentin Matrix Protein 1 (DMP1) Expression in Osteocytes In Vivo
2003
Chimeric Influenza Virus Hemagglutinin Proteins Containing Large Domains of the Bacillus anthracis Protective Antigen: Protein Characterization, Incorporation into Infectious Influenza Viruses, and Antigenicity
2005
Antigenic properties of a transport-competent influenza HA/HIV Env chimeric protein
2006
Incorporation of High Levels of Chimeric Human Immunodeficiency Virus Envelope Glycoproteins into Virus-Like Particles
2007
An ultra-low-cost electroporator with microneedle electrodes (ePatch) for SARS-CoV-2 vaccination
2021
BMP signaling negatively regulates bone mass through sclerostin by inhibiting the canonical Wnt pathway
2008
Solvothermal Syntheses and Structural Characterisation of Three Isostructural 3D Metal‐Malate Coordination Polymers: {[M(C4H4O5)(H2O)]·H2O}n (M = CoII, NiII, CoII/NiII)
2004
Disruption of BMP Signaling in Osteoblasts Through Type IA Receptor (BMPRIA) Increases Bone Mass
2008
Direct Electrical Communication between Graphite Electrodes and Surface Adsorbed Glucose Oxidase/Redox Polymer Complexes
1990