Citation Impact
Citing Papers
Phosphorylation of ULK1 (hATG1) by AMP-Activated Protein Kinase Connects Energy Sensing to Mitophagy
2010 StandoutScience
Phosphorylation and Regulation of Akt/PKB by the Rictor-mTOR Complex
2005 StandoutScience
Requirement of bic/microRNA-155 for Normal Immune Function
2007 StandoutScience
Tight and specific lanthanide binding in a de novo TIM barrel with a large internal cavity designed by symmetric domain fusion
2020 StandoutNobel
PIEZOs mediate neuronal sensing of blood pressure and the baroreceptor reflex
2018 StandoutScienceNobel
The Rag GTPases Bind Raptor and Mediate Amino Acid Signaling to mTORC1
2008 StandoutScience
Fat Metabolism Links Germline Stem Cells and Longevity in C. elegans
2008 StandoutScienceNobel
TOR Signaling in Growth and Metabolism
2006 Standout
Comprehensive genomic characterization defines human glioblastoma genes and core pathways
2008 StandoutNature
Differential Membrane Localization of ERas and Rheb, Two Ras-related Proteins Involved in the Phosphatidylinositol 3-Kinase/mTOR Pathway
2005 StandoutNobel
mTOR Signaling in Growth Control and Disease
2012 Standout
PRAS40 Is an Insulin-Regulated Inhibitor of the mTORC1 Protein Kinase
2007
Genetic effects on gene expression across human tissues
2017 StandoutNature
The Tuberous Sclerosis Complex
2006 Standout
Will mTOR inhibitors make it as cancer drugs?
2003
The tor pathway: a target for cancer therapy
2004 Standout
Inactivation of the Tuberous Sclerosis Complex-1 and -2 Gene Products Occurs by Phosphoinositide 3-Kinase/Akt-dependent and -independent Phosphorylation of Tuberin
2003
Rheb Binds Tuberous Sclerosis Complex 2 (TSC2) and Promotes S6 Kinase Activation in a Rapamycin- and Farnesylation-dependent Manner
2003
Rheb is a direct target of the tuberous sclerosis tumour suppressor proteins
2003
Influence of Metabolism on Epigenetics and Disease
2013 StandoutNobel
Growing roles for the mTOR pathway
2005
High-resolution cryo-electron microscopy structure of the Trypanosoma brucei ribosome
2013 StandoutNatureNobel
The genetics of ageing
2010 StandoutNature
Signalling through RHEB-1 mediates intermittent fasting-induced longevity in C. elegans
2008 Nature
Regulation of mTOR function in response to hypoxia by REDD1 and the TSC1/TSC2 tumor suppressor complex
2004 StandoutNobel
Sphingolipids and their metabolism in physiology and disease
2017 Standout
Wound repair and regeneration
2008 StandoutNature
Drosophila dFOXO controls lifespan and regulates insulin signalling in brain and fat body
2004 Nature
Loss of the Tuberous Sclerosis Complex Tumor Suppressors Triggers the Unfolded Protein Response to Regulate Insulin Signaling and Apoptosis
2008
Blood Pressure Regulation by the Rostral Ventrolateral Medulla in Conscious Rats: Effects of Hypoxia, Hypercapnia, Baroreceptor Denervation, and Anesthesia
2017
The road to fully programmable protein catalysis
2022 StandoutNatureNobel
Tuberous Sclerosis Complex Gene Products, Tuberin and Hamartin, Control mTOR Signaling by Acting as a GTPase-Activating Protein Complex toward Rheb
2003 Standout
Localization of Rheb to the endomembrane is critical for its signaling function
2006
The NOX Family of ROS-Generating NADPH Oxidases: Physiology and Pathophysiology
2007 Standout
Network organization of the human autophagy system
2010 StandoutNature
Upstream and downstream of mTOR
2004 Standout
Cell-Type Independent MYC Target Genes Reveal a Primordial Signature Involved in Biomass Accumulation
2011
TSC2 regulates VEGF through mTOR-dependent and -independent pathways
2003 StandoutNobel
Chapter 1 Physiological Roles of Ribosomal Protein S6: One of Its Kind
2008
Phosphorylation and Functional Inactivation of TSC2 by Erk
2005 Standout
The kinase mTOR regulates the differentiation of helper T cells through the selective activation of signaling by mTORC1 and mTORC2
2011
Rheb Binds and Regulates the mTOR Kinase
2005
Hypoxia in cancer: significance and impact on clinical outcome
2007 Standout
mTOR: from growth signal integration to cancer, diabetes and ageing
2010 Standout
Rapamycin fed late in life extends lifespan in genetically heterogeneous mice
2009 StandoutNature
Emergence of a catalytic tetrad during evolution of a highly active artificial aldolase
2016 StandoutNobel
Stress and mTORture signaling
2006
“New” hepatic fat activates PPARα to maintain glucose, lipid, and cholesterol homeostasis
2005
Identification of Dominant Negative Mutants of Rheb GTPase and Their Use to Implicate the Involvement of Human Rheb in the Activation of p70S6K
2003
A Nutrient Sensor Mechanism Controls Drosophila Growth
2003
Insulin Stimulates Adipogenesis through the Akt-TSC2-mTORC1 Pathway
2009
Control of TH17/Treg Balance by Hypoxia-Inducible Factor 1
2011 StandoutNobel
Neurogenesis and the Cell Cycle
2003
Mechanisms for Insulin Resistance: Common Threads and Missing Links
2012 Standout
Glypican-1 identifies cancer exosomes and detects early pancreatic cancer
2015 StandoutNature
Phosphoinositides in cell regulation and membrane dynamics
2006 StandoutNature
The Folliculin Tumor Suppressor Is a GAP for the RagC/D GTPases That Signal Amino Acid Levels to mTORC1
2013
Regulation of TORC1 by Rag GTPases in nutrient response
2008
Regulation of B-Raf Kinase Activity by Tuberin and Rheb Is Mammalian Target of Rapamycin (mTOR)-independent
2004
TSC2 Integrates Wnt and Energy Signals via a Coordinated Phosphorylation by AMPK and GSK3 to Regulate Cell Growth
2006 Standout
Macrophage biology in development, homeostasis and disease
2013 StandoutNature
Oxygen Sensing, Homeostasis, and Disease
2011 StandoutNobel
Ras, PI(3)K and mTOR signalling controls tumour cell growth
2006 StandoutNature
Brat Is a Miranda Cargo Protein that Promotes Neuronal Differentiation and Inhibits Neuroblast Self-Renewal
2006
Regulation of mTORC1 by amino acids
2014
Termination of autophagy and reformation of lysosomes regulated by mTOR
2010 StandoutNature
The hypoxia-induced paralogs Scylla and Charybdis inhibit growth by down-regulating S6K activity upstream of TSC in Drosophila
2004
Mice cloned from olfactory sensory neurons
2004 StandoutNatureNobel
Biomarkers for pancreatic cancer: promising new markers and options beyond CA 19-9
2013
Tsc1+ and tsc2+ Regulate Arginine Uptake and Metabolism in Schizosaccharomyces pombe
2004
Target of rapamycin (TOR): an integrator of nutrient and growth factor signals and coordinator of cell growth and cell cycle progression
2004 Standout
Oncogenic PI3K deregulates transcription and translation
2005
The TSC1-2 tumor suppressor controls insulin–PI3K signaling via regulation of IRS proteins
2004 Standout
Signaling from Akt to FRAP/TOR Targets both 4E-BP and S6K in Drosophila melanogaster
2003
Recombinant human erythropoietin protects the myocardium from ischemia-reperfusion injury and promotes beneficial remodeling
2003
Nutrients Suppress Phosphatidylinositol 3-Kinase/Akt Signaling via Raptor-Dependent mTOR-Mediated Insulin Receptor Substrate 1 Phosphorylation
2005
Amino acids mediate mTOR/raptor signaling through activation of class 3 phosphatidylinositol 3OH-kinase
2005
Digoxin and other cardiac glycosides inhibit HIF-1α synthesis and block tumor growth
2008 StandoutNobel
Tissue engineering of replacement skin: the crossroads of biomaterials, wound healing, embryonic development, stem cells and regeneration
2006
Biosynthesis of the Caenorhabditis elegans dauer pheromone
2009 StandoutNobel
eIF3d is an mRNA cap-binding protein that is required for specialized translation initiation
2016 StandoutNatureNobel
mTOR Controls Cell Cycle Progression through Its Cell Growth Effectors S6K1 and 4E-BP1/Eukaryotic Translation Initiation Factor 4E
2003
Understanding Nanomaterial–Liver Interactions to Facilitate the Development of Safer Nanoapplications
2022
pVHL suppresses kinase activity of Akt in a proline-hydroxylation–dependent manner
2016 StandoutScienceNobel
The Versatile Role of microRNA-30a in Human Cancer
2017 Standout
ULK-Atg13-FIP200 Complexes Mediate mTOR Signaling to the Autophagy Machinery
2009 Standout
Human Fatty Liver Disease: Old Questions and New Insights
2011 StandoutScience
Phosphatidylinositol-3-Kinase Signaling Is Required for Erythropoietin-Mediated Acute Protection Against Myocardial Ischemia/Reperfusion Injury
2004 StandoutNobel
Sudestada1, a Drosophila ribosomal prolyl-hydroxylase required for mRNA translation, cell homeostasis, and organ growth
2014 StandoutNobel
Disruption of the Mouse mTOR Gene Leads to Early Postimplantation Lethality and Prohibits Embryonic Stem Cell Development
2004
mTOR: a pharmacologic target for autophagy regulation
2015 Standout
Fibrinogen as a key regulator of inflammation in disease
2011
DrosophilaRheb GTPase is required for cell cycle progression and cell growth
2003
TOR Signaling
2003
Dysregulation of the TSC-mTOR pathway in human disease
2004 Standout
Rag GTPases mediate amino acid–dependent recruitment of TFEB and MITF to lysosomes
2013
Fast detection of liver fibrosis with collagen-binding single-nanometer iron oxide nanoparticles via T 1 -weighted MRI
2023 StandoutNobel
Works of Ling Li being referenced
Nutritional control of gene expression in Drosophila larvae via TOR, Myc and a novel cis-regulatory element
2010
The hepatotoxicity of multi-walled carbon nanotubes in mice
2009
Morphological evidence of reinnervation of the baroreceptive regions in sinoaortic‐denervated rats
2003
Hoxb13 Up-regulates Transglutaminase Activity and Drives Terminal Differentiation in an Epidermal Organotypic Model
2005
Serial Hypoxia Imaging With 99mTc-HL91 SPECT to Predict Radiotherapy Response in Nonsmall Cell Lung Cancer
2006
MicroRNA miR-34 Inhibits Human Pancreatic Cancer Tumor-Initiating Cells
2009
Rheb promotes cell growth as a component of the insulin/TOR signalling network
2003
Ceramide as a Mediator of Non-Alcoholic Fatty Liver Disease and Associated Atherosclerosis
2015
Characterization, Kinetics, and Crystal Structures of Fructose-1,6-bisphosphate Aldolase from the Human Parasite, Giardia lamblia
2006
The IL-1β/AP-1/miR-30a/ADAMTS-5 axis regulates cartilage matrix degradation in human osteoarthritis
2016
The adipose triglyceride lipase, adiponectin and visfatin are downregulated by tumor necrosis factor-α (TNF-α) in vivo
2008
Peroxisome proliferator-activated receptor α and γ agonists upregulate human macrophage lipoprotein lipase expression
2002
Signaling Pathways Involved in Human Vascular Smooth Muscle Cell Proliferation and Matrix Metalloproteinase-2 Expression Induced by Leptin
2005
Akt Activation Preserves Cardiac Function and Prevents Injury After Transient Cardiac Ischemia In Vivo
2001
Pan-neural Prospero terminates cell proliferation during Drosophila neurogenesis
2000
Fibrinogen is required for maintenance of platelet intracellular and cell-surface P-selectin expression
2009