Citation Impact
Citing Papers
Mitochondrial dysfunction in Parkinson's disease
2016
Phosphorylation of ULK1 (hATG1) by AMP-Activated Protein Kinase Connects Energy Sensing to Mitophagy
2010 StandoutScience
Dopamine oxidation mediates mitochondrial and lysosomal dysfunction in Parkinson’s disease
2017 Science
Pathological α-Synuclein Transmission Initiates Parkinson-like Neurodegeneration in Nontransgenic Mice
2012 StandoutScience
Nrf2-mediated neuroprotection in the MPTP mouse model of Parkinson's disease: Critical role for the astrocyte
2009
PINK1-dependent recruitment of Parkin to mitochondria in mitophagy
2009 Standout
The Role of Oxidative Stress in Parkinson's Disease
2013
Phospholipid methylation controls Atg32‐mediated mitophagy and Atg8 recycling
2015 StandoutNobel
Phosphatase and Tensin Homolog (PTEN)-induced Putative Kinase 1 (PINK1)-dependent Ubiquitination of Endogenous Parkin Attenuates Mitophagy
2012
FoxOs Enforce a Progression Checkpoint to Constrain mTORC1-Activated Renal Tumorigenesis
2010 StandoutNobel
Astrocytes: biology and pathology
2009 Standout
A Neo-Substrate that Amplifies Catalytic Activity of Parkinson’s-Disease-Related Kinase PINK1
2013
Parkinson disease
2017 Standout
Signals from the lysosome: a control centre for cellular clearance and energy metabolism
2013 Standout
Recent advances in our understanding of neurodegeneration
2009
Oxidation of the cysteine-rich regions of parkin perturbs its E3 ligase activity and contributes to protein aggregation
2011
Parkinson's disease
2021 Standout
PINK1/Parkin-mediated mitophagy is dependent on VDAC1 and p62/SQSTM1
2010 Standout
AMPK: guardian of metabolism and mitochondrial homeostasis
2017 Standout
Mechanism and medical implications of mammalian autophagy
2018 Standout
Parkin mitochondrial translocation is achieved through a novel catalytic activity coupled mechanism
2013
Autophagy and the Integrated Stress Response
2010 Standout
Mechanisms Underlying Inflammation in Neurodegeneration
2010 Standout
Pathological roles of MAPK signaling pathways in human diseases
2010 Standout
Parkin is a lipid-responsive regulator of fat uptake in mice and mutant human cells
2011
Association of PINK1 and DJ-1 confers digenic inheritance of early-onset Parkinson's disease
2006
The role of autophagy in neurodegenerative disease
2013 Standout
Autophagy in mammalian development and differentiation
2010 Standout
Epidermal growth factor receptor mutations in lung cancer
2007 Standout
Molecular pathogenesis of Parkinson disease: insights from genetic studies
2009
PINK1 Is Selectively Stabilized on Impaired Mitochondria to Activate Parkin
2010 Standout
The Roles of PINK1, Parkin, and Mitochondrial Fidelity in Parkinson’s Disease
2015 Standout
Phosphorylation of parkin by Parkinson disease-linked kinase PINK1 activates parkin E3 ligase function and NF- B signaling
2009
An RNA-Sequencing Transcriptome and Splicing Database of Glia, Neurons, and Vascular Cells of the Cerebral Cortex
2014 Standout
Interplay between Cytosolic Dopamine, Calcium, and α-Synuclein Causes Selective Death of Substantia Nigra Neurons
2009
Mitochondrial fusion and fission in cell life and death
2010 Standout
Autophagy: Renovation of Cells and Tissues
2011 Standout
Biological Functions of Autophagy Genes: A Disease Perspective
2019 Standout
Mitochondria: In Sickness and in Health
2012 Standout
Targeting the phosphoinositide 3-kinase pathway in cancer
2009 Standout
PINK1 is activated by mitochondrial membrane potential depolarization and stimulates Parkin E3 ligase activity by phosphorylating Serine 65
2012
Gut Microbiota Regulate Motor Deficits and Neuroinflammation in a Model of Parkinson’s Disease
2016 Standout
Blinded by the Light: The Growing Complexity of p53
2009 Standout
Reactive oxygen species (ROS) as pleiotropic physiological signalling agents
2020 Standout
Parkinson's disease
2015 Standout
Beyond PTEN mutations: the PI3K pathway as an integrator of multiple inputs during tumorigenesis
2006
Scientific rationale for the development of gene therapy strategies for Parkinson's disease
2009
Autophagy in the Pathogenesis of Disease
2008 Standout
PINK1-linked parkinsonism is associated with Lewy body pathology
2010
Parkinson's Disease: Gene Therapies
2012
Autophagy in Human Health and Disease
2013 Standout
Mechanisms of mitophagy
2010 Standout
Copper-Zinc Superoxide Dismutase (SOD1) Is Released by Microglial Cells and Confers Neuroprotection against 6-OHDA Neurotoxicity
2012 Standout
Value of genetic models in understanding the cause and mechanisms of Parkinson’s disease
2008
Mitochondrial Quality Control Mediated by PINK1 and Parkin: Links to Parkinsonism
2012 Nobel
A tale on animal models of Parkinson's disease
2011
Endogenous Parkin Preserves Dopaminergic Substantia Nigral Neurons following Mitochondrial DNA Mutagenic Stress
2015
Neurotoxic in vivo models of Parkinson’s disease
2010
Basic mechanisms of neurodegeneration: a critical update
2010
Mitochondrial dysfunction and oxidative stress in neurodegenerative diseases
2006 StandoutNature
Role of PINK1 Binding to the TOM Complex and Alternate Intracellular Membranes in Recruitment and Activation of the E3 Ligase Parkin
2012
Non-motor features of Parkinson disease
2017 Standout
p53‐dependent neuronal cell death in a DJ‐1‐deficient zebrafish model of Parkinson's disease
2006
Repertoires of Autophagy in the Pathogenesis of Ocular Diseases
2015 Standout
Systematic Mutagenesis of α-Synuclein Reveals Distinct Sequence Requirements for Physiological and Pathological Activities
2012 StandoutNobel
Autophagy-related Protein 32 Acts as Autophagic Degron and Directly Initiates Mitophagy
2012 StandoutNobel
The ubiquitin kinase PINK1 recruits autophagy receptors to induce mitophagy
2015 StandoutNature
Structure of the human Parkin ligase domain in an autoinhibited state
2013
Targeting Mitochondrial Dysfunction: Role for PINK1 and Parkin in Mitochondrial Quality Control
2011
DJ-1 gene deletion reveals that DJ-1 is an atypical peroxiredoxin-like peroxidase
2007
Recent Advances in the Genetics of Parkinson's Disease
2011
Role of Nrf2 in Oxidative Stress and Toxicity
2013 Standout
Native α-synuclein induces clustering of synaptic-vesicle mimics via binding to phospholipids and synaptobrevin-2/VAMP2
2013 StandoutNobel
Genetic mouse models of Parkinson’s disease
2010
Regulation of astrocyte inflammatory responses by the Parkinson's disease‐associated gene DJ–1
2009
What Genetics Tells us About the Causes and Mechanisms of Parkinson's Disease
2011
KEGG: integrating viruses and cellular organisms
2020 Standout
Inactivation of Drosophila DJ-1 leads to impairments of oxidative stress response and phosphatidylinositol 3-kinase/Akt signaling
2005
Bioenergetics and translational metabolism: implications for genetics, physiology and precision medicine
2019
Ubiquitin and Parkinson's disease through the looking glass of genetics
2017
Autophagy and Metabolism
2010 StandoutScience
The Ubiquitin Code
2012 Standout
Normal development is an integral part of tumorigenesis in T cell-specific PTEN-deficient mice
2008 StandoutNobel
PINK1 stabilized by mitochondrial depolarization recruits Parkin to damaged mitochondria and activates latent Parkin for mitophagy
2010 Standout
Genes associated with Parkinson's disease: regulation of autophagy and beyond
2015
Neuronal vulnerability, pathogenesis, and Parkinson's disease
2012
Gene Therapy for Dopamine Replacement in Parkinson´s Disease
2009
Regulation of Mammalian Autophagy in Physiology and Pathophysiology
2010 Standout
Mouse neurexin-1α deletion causes correlated electrophysiological and behavioral changes consistent with cognitive impairments
2009 StandoutNobel
The Role of Atg Proteins in Autophagosome Formation
2011 StandoutNobel
Works of Linan Chen being referenced
Drp1 inhibition attenuates neurotoxicity and dopamine release deficits in vivo
2014
A53T Human α-Synuclein Overexpression in Transgenic Mice Induces Pervasive Mitochondria Macroautophagy Defects Preceding Dopamine Neuron Degeneration
2015
Unregulated Cytosolic Dopamine Causes Neurodegeneration Associated with Oxidative Stress in Mice
2008
Parkin, PINK1, and DJ-1 form a ubiquitin E3 ligase complex promoting unfolded protein degradation
2009
Age-dependent Motor Deficits and Dopaminergic Dysfunction in DJ-1 Null Mice
2005