Citation Impact
Citing Papers
MEX-5 asymmetry in one-cell C. elegans embryos requires PAR-4-and PAR-1-dependent phosphorylation
2008
Phosphorylation of ULK1 (hATG1) by AMP-Activated Protein Kinase Connects Energy Sensing to Mitophagy
2010 StandoutScience
Germline P Granules Are Liquid Droplets That Localize by Controlled Dissolution/Condensation
2009 StandoutScience
Immunohistochemical Loss of LKB1 Is a Biomarker for More Aggressive Biology in KRAS -Mutant Lung Adenocarcinoma
2015
AMP-activated protein kinase regulates the assembly of epithelial tight junctions
2006
The tumor suppressor LKB1 kinase directly activates AMP-activated kinase and regulates apoptosis in response to energy stress
2004 Standout
The Kinase LKB1 Mediates Glucose Homeostasis in Liver and Therapeutic Effects of Metformin
2005 StandoutScience
The energy sensing LKB1–AMPK pathway regulates p27kip1 phosphorylation mediating the decision to enter autophagy or apoptosis
2007
Insulin Antagonizes Ischemia-induced Thr172 Phosphorylation of AMP-activated Protein Kinase α-Subunits in Heart via Hierarchical Phosphorylation of Ser485/491
2005
AMP-activated Protein Kinase (AMPK) Activation and Glycogen Synthase Kinase-3β (GSK-3β) Inhibition Induce Ca2+-independent Deposition of Tight Junction Components at the Plasma Membrane
2011
AMP Is a True Physiological Regulator of AMP-Activated Protein Kinase by Both Allosteric Activation and Enhancing Net Phosphorylation
2013
Hallmarks of Cancer: The Next Generation
2011 Standout
AMPK regulates energy expenditure by modulating NAD+ metabolism and SIRT1 activity
2009 StandoutNature
Metformin Retards Aging in C. elegans by Altering Microbial Folate and Methionine Metabolism
2013
Activity of LKB1 and AMPK-related kinases in skeletal muscle: effects of contraction, phenformin, and AICAR
2004
Mechanisms of regulation of SNF1/AMPK/SnRK1 protein kinases
2014
AMP-activated protein kinase: also regulated by ADP?
2011
The tumor suppressor kinase LKB1: lessons from mouse models
2011
Regulation of the TSC pathway by LKB1: evidence of a molecular link between tuberous sclerosis complex and Peutz-Jeghers syndrome
2004
Base-excision repair of oxidative DNA damage
2007 StandoutNature
Cannabinoids and Ghrelin Have Both Central and Peripheral Metabolic and Cardiac Effects via AMP-activated Protein Kinase
2005
AMPK signalling in health and disease
2017
Complete Polarization of Single Intestinal Epithelial Cells upon Activation of LKB1 by STRAD
2004
Identification and characterization of a small molecule AMPK activator that treats key components of type 2 diabetes and the metabolic syndrome
2006
KIN‐29 SIK regulates chemoreceptor gene expression via an MEF2 transcription factor and a class II HDAC
2006
AMPK Is a Negative Regulator of the Warburg Effect and Suppresses Tumor Growth In Vivo
2012
mTOR Signaling in Growth Control and Disease
2012 Standout
The CREB coactivator TORC2 is a key regulator of fasting glucose metabolism
2005 Nature
The LKB1/AMPK polarity pathway
2010
AMPK: guardian of metabolism and mitochondrial homeostasis
2017 Standout
Regulation of AMP‐activated protein kinase by a pseudosubstrate sequence on the γ subunit
2007
AMP-activated protein kinase: Ancient energy gauge provides clues to modern understanding of metabolism
2005 Standout
Influence of Metabolism on Epigenetics and Disease
2013 StandoutNobel
Use of Cells Expressing γ Subunit Variants to Identify Diverse Mechanisms of AMPK Activation
2010
AKT/PKB Signaling: Navigating Downstream
2007 Standout
New roles for the LKB1→AMPK pathway
2005
Mammalian TAK1 Activates Snf1 Protein Kinase in Yeast and Phosphorylates AMP-activated Protein Kinase in Vitro
2006
AMP-Activated Protein Kinase Induces a p53-Dependent Metabolic Checkpoint
2005
Central nervous system control of food intake and body weight
2006 StandoutNature
Fatal Congenital Heart Glycogenosis Caused by a Recurrent Activating R531Q Mutation in the γ2-Subunit of AMP-Activated Protein Kinase (PRKAG2), Not by Phosphorylase Kinase Deficiency
2005
AMP-kinase regulates food intake by responding to hormonal and nutrient signals in the hypothalamus
2004 Nature
The genetics of ageing
2010 StandoutNature
Calmodulin-dependent protein kinase kinase-β is an alternative upstream kinase for AMP-activated protein kinase
2005
The AMPK signalling pathway coordinates cell growth, autophagy and metabolism
2011 Standout
Regulation of mTOR function in response to hypoxia by REDD1 and the TSC1/TSC2 tumor suppressor complex
2004 StandoutNobel
Development of protein kinase activators: AMPK as a target in metabolic disorders and cancer
2009
Contraction-mediated phosphorylation of AMPK is lower in skeletal muscle of adenylate kinase-deficient mice
2005
Genetics of hereditary colorectal cancer
2005
AMP-activated Protein Kinase β Subunit Tethers α and γ Subunits via Its C-terminal Sequence (186–270)
2005
Deficiency of LKB1 in heart prevents ischemia-mediated activation of AMPKα2 but not AMPKα1
2005
Genetic model for the chronic activation of skeletal muscle AMP-activated protein kinase leads to glycogen accumulation
2006
Role of adiponectin in human skeletal muscle bioenergetics
2006
Degradation of AMPK by a Cancer-Specific Ubiquitin Ligase
2015
AMP as a Low-Energy Charge Signal Autonomously Initiates Assembly of AXIN-AMPK-LKB1 Complex for AMPK Activation
2013
Akt-dependent transformation: there is more to growth than just surviving
2005
Activation of AKT Kinases in Cancer: Implications for Therapeutic Targeting
2005
LKB1 and AMPK Family Signaling: The Intimate Link Between Cell Polarity and Energy Metabolism
2009
Ca2+/calmodulin-dependent protein kinase kinase-β acts upstream of AMP-activated protein kinase in mammalian cells
2005
Ablation of LKB1 in the heart leads to energy deprivation and impaired cardiac function
2010
5-Aminoimidazole-4-carboxamide-1-β-D-ribofuranoside Inhibits Cancer Cell Proliferation in Vitro and in Vivo via AMP-activated Protein Kinase
2005
Human nutrition, the gut microbiome and the immune system
2011 StandoutNature
Macrophage-specific PPARγ controls alternative activation and improves insulin resistance
2007 StandoutNature
mTOR Signaling in Growth, Metabolism, and Disease
2017 Standout
TSC2 Mediates Cellular Energy Response to Control Cell Growth and Survival
2003 Standout
Resveratrol Ameliorates Aging-Related Metabolic Phenotypes by Inhibiting cAMP Phosphodiesterases
2012
AMPK is essential for energy homeostasis regulation and glucose sensing by POMC and AgRP neurons
2007
AMPK at the Nexus of Energetics and Aging
2014
Metformin suppresses gluconeogenesis by inhibiting mitochondrial glycerophosphate dehydrogenase
2014 StandoutNature
Dynein Modifiers in C. elegans: Light Chains Suppress Conditional Heavy Chain Mutants
2007
Activating AMP-Activated Protein Kinase without AMP
2005
Fatal Infantile Cardiac Glycogenosis with Phosphorylase Kinase Deficiency and a Mutation in the γ2-Subunit of AMP-Activated Protein Kinase
2007
Tumor suppressors and cell metabolism: a recipe for cancer growth
2009
Metformin Induces a Dietary Restriction–Like State and the Oxidative Stress Response to Extend C. elegans Healthspan via AMPK, LKB1, and SKN-1
2010
Autophagy in the Pathogenesis of Disease
2008 Standout
Serum retinol binding protein 4 contributes to insulin resistance in obesity and type 2 diabetes
2005 StandoutNature
The LKB1–AMPK pathway: metabolism and growth control in tumour suppression
2009
The MicroRNA miR-1 Regulates a MEF-2-Dependent Retrograde Signal at Neuromuscular Junctions
2008 StandoutNobel
Structural Insight into AMPK Regulation: ADP Comes into Play
2007
AMPK activation: a therapeutic target for type 2 diabetes?
2014
Nutritional stress in eukaryotic cells: Oxidative species and regulation of survival in time of scarceness
2011
Structural basis of AMPK regulation by small molecule activators
2013
AMPK functions as an adenylate charge-regulated protein kinase
2012
Establishing Neuronal Polarity with Environmental and Intrinsic Mechanisms
2017
LKB1; linking cell structure and tumor suppression
2008
Aging networks in Caenorhabditis elegans: AMP‐activated protein kinase (aak‐2) links multiple aging and metabolism pathways
2006
AMP-activated protein kinase and its downstream transcriptional pathways
2010
Regulation of LKB1/STRAD Localization and Function by E-Cadherin
2008
Metformin inhibits hepatic gluconeogenesis in mice independently of the LKB1/AMPK pathway via a decrease in hepatic energy state
2010
Deficiency of LKB1 in skeletal muscle prevents AMPK activation and glucose uptake during contraction
2005
AMP-activated Protein Kinase and the Regulation of Autophagic Proteolysis
2006
AMP-activated Protein Kinase Is Required for the Lipid-lowering Effect of Metformin in Insulin-resistant Human HepG2 Cells
2004
Repositioning metformin for cancer prevention and treatment
2013
AMP-activated/SNF1 protein kinases: conserved guardians of cellular energy
2007 Standout
Exosomes facilitate therapeutic targeting of oncogenic KRAS in pancreatic cancer
2017 StandoutNature
A Hormone-Dependent Module Regulating Energy Balance
2011
Neuronal polarity in C. elegans
2010
AMP-activated Protein Kinase Plays a Role in the Control of Food Intake
2004
The LKB1 tumor suppressor negatively regulates mTOR signaling
2004
The role of autophagy during the early neonatal starvation period
2004 StandoutNatureNobel
The Lysosomal v-ATPase-Ragulator Complex Is a Common Activator for AMPK and mTORC1, Acting as a Switch between Catabolism and Anabolism
2014
CNTF reverses obesity-induced insulin resistance by activating skeletal muscle AMPK
2006
The Hallmarks of Aging
2013 Standout
Bateman domains and adenosine derivatives form a binding contract
2004
Ras, PI(3)K and mTOR signalling controls tumour cell growth
2006 StandoutNature
Peripheral Chemoreceptors: Function and Plasticity of the Carotid Body
2012
Cardiac-specific Deletion of LKB1 Leads to Hypertrophy and Dysfunction
2009
The Ca2+/Calmodulin-dependent Protein Kinase Kinases Are AMP-activated Protein Kinase Kinases
2005
Wnt signalling in stem cells and cancer
2005 StandoutNature
Autophagy regulation by nutrient signaling
2013
Glycogen debranching enzyme association with β-subunit regulates AMP-activated protein kinase activity
2005
Pyruvate Kinase M2 Is a PHD3-Stimulated Coactivator for Hypoxia-Inducible Factor 1
2011 StandoutNobel
AMPK: a nutrient and energy sensor that maintains energy homeostasis
2012 Standout
Fuel feeds function: energy metabolism and the T-cell response
2005
The Energy Sensor AMP-activated Protein Kinase Directly Regulates the Mammalian FOXO3 Transcription Factor
2007
Angiogenesis as a therapeutic target
2005 StandoutNature
Genetics and biology of pancreatic ductal adenocarcinoma
2006
The CREB Coactivator TORC2 Functions as a Calcium- and cAMP-Sensitive Coincidence Detector
2004
Regulation of the MEX-5 Gradient by a Spatially Segregated Kinase/Phosphatase Cycle
2011
Target of rapamycin (TOR): an integrator of nutrient and growth factor signals and coordinator of cell growth and cell cycle progression
2004 Standout
Metformin and reduced risk of cancer in diabetic patients
2005 Standout
Adenosine Monophosphate-Activated Protein Kinase: A Central Regulator of Metabolism with Roles in Diabetes, Cancer, and Viral Infection
2011
Dysregulation of HIF and VEGF is a unifying feature of the familial hamartoma syndromes
2004 StandoutNobel
The AMP-activated protein kinase AAK-2 links energy levels and insulin-like signals to lifespan in C. elegans
2004
Function of Mammalian LKB1 and Ca2+/Calmodulin-dependent Protein Kinase Kinase α as Snf1-activating Kinases in Yeast
2005
Predominant α2/β2/γ3 AMPK activation during exercise in human skeletal muscle
2006
AMP-Activated Protein Kinase in Metabolic Control and Insulin Signaling
2007
Important role of the LKB1–AMPK pathway in suppressing tumorigenesis in PTEN-deficient mice
2008
AMPK and mTOR in Cellular Energy Homeostasis and Drug Targets
2011
Nutrients Suppress Phosphatidylinositol 3-Kinase/Akt Signaling via Raptor-Dependent mTOR-Mediated Insulin Receptor Substrate 1 Phosphorylation
2005
Identification of a Nuclear Export Signal in the Catalytic Subunit of AMP-activated Protein Kinase
2010
AMPK Promotes Aberrant PGC1β Expression To Support Human Colon Tumor Cell Survival
2015
Digoxin and other cardiac glycosides inhibit HIF-1α synthesis and block tumor growth
2008 StandoutNobel
AMP-Activated Protein Kinase in the Heart
2007
Regulation of the energy sensor AMP-activated protein kinase by antigen receptor and Ca2+ in T lymphocytes
2006
AMP-Activated Protein Kinase Induces p53 by Phosphorylating MDMX and Inhibiting Its Activity
2013
ERK and p38 MAPK-Activated Protein Kinases: a Family of Protein Kinases with Diverse Biological Functions
2004 Standout
Bateman domains and adenosine derivatives form a binding contract
2004
Diverse Cytopathologies in Mitochondrial Disease Are Caused by AMP-activated Protein Kinase Signaling
2007
Investigating the mechanism for AMP activation of the AMP-activated protein kinase cascade
2007
AMP-Activated Protein Kinase as a Drug Target
2006
The ubiquitin-associated domain of AMPK-related kinases regulates conformation and LKB1-mediated phosphorylation and activation
2006
Pemetrexed Indirectly Activates the Metabolic Kinase AMPK in Human Carcinomas
2010
Lysosomal activity regulatesCaenorhabditis elegansmitochondrial dynamics through vitamin B12 metabolism
2020 StandoutNobel
Dialogue between E. coli free radical pathways and the mitochondria of C. elegans
2015 StandoutNobel
STRADα Regulates LKB1 Localization by Blocking Access to Importin-α, and by Association with Crm1 and Exportin-7
2008
The AMP-activated protein kinase cascade – a unifying system for energy control
2003
AMP-activated protein kinase (AMPK) is a tau kinase, activated in response to amyloid β-peptide exposure
2011
Hypoxia Triggers AMPK Activation through Reactive Oxygen Species-Mediated Activation of Calcium Release-Activated Calcium Channels
2011
Lkb1 Deletion Promotes Ectopic Lipid Accumulation in Muscle Progenitor Cells and Mature Muscles
2014
Role of AMPK-mTOR-Ulk1/2 in the Regulation of Autophagy: Cross Talk, Shortcuts, and Feedbacks
2011
Regulation of Caenorhabditis elegans neuronal polarity by heterochronic genes
2019 StandoutNobel
Osmosensory signaling in Mycobacterium tuberculosis mediated by a eukaryotic-like Ser/Thr protein kinase
2013 StandoutNobel
Spermidine in health and disease
2018 StandoutScience
The AMP-activated protein kinase pathway – new players upstream and downstream
2004
Thrombin Activates AMP-Activated Protein Kinase in Endothelial Cells via a Pathway Involving Ca2+/Calmodulin-Dependent Protein Kinase Kinase β
2006
LKB1-Dependent Signaling Pathways
2006
Regulation of epithelial tight junction assembly and disassembly by AMP-activated protein kinase
2007
AMP-activated protein kinase (AMPK) activity is not required for neuronal development but regulates axogenesis during metabolic stress
2011
Current understanding of metformin effect on the control of hyperglycemia in diabetes
2016
Metabolic reprogramming and cancer progression
2020 StandoutScience
Complementary roles of gasotransmitters CO and H2S in sleep apnea
2017 StandoutNobel
Establishment of Axon-Dendrite Polarity in Developing Neurons
2009
Resveratrol stimulates AMP kinase activity in neurons
2007
A pivotal role for endogenous TGF-β-activated kinase-1 in the LKB1/AMP-activated protein kinase energy-sensor pathway
2006
Interleukin-6 Regulation of AMP-Activated Protein Kinase
2006
Autophagy and Metabolism
2010 StandoutScience
Differential regulation by AMP and ADP of AMPK complexes containing different γ subunit isoforms
2015
Probing the enzyme kinetics, allosteric modulation and activation of α1- and α2-subunit-containing AMP-activated protein kinase (AMPK) heterotrimeric complexes by pharmacological and physiological activators
2015
Hypoxia. 2. Hypoxia regulates cellular metabolism
2010
Mitochondrial and performance adaptations to exercise training in mice lacking skeletal muscle LKB1
2013
AMPK: A Key Sensor of Fuel and Energy Status in Skeletal Muscle
2006
AMPK regulation of fatty acid metabolism and mitochondrial biogenesis: Implications for obesity
2012
Calmodulin-dependent protein kinase kinase-β activates AMPK without forming a stable complex: synergistic effects of Ca2+ and AMP
2009
Identification of Protor as a novel Rictor-binding component of mTOR complex-2
2007
New Roles for the LKB1-NUAK Pathway in Controlling Myosin Phosphatase Complexes and Cell Adhesion
2010
Mitochondrial activation chemicals synergize with surface receptor PD-1 blockade for T cell-dependent antitumor activity
2017 StandoutNobel
Dysregulation of the TSC-mTOR pathway in human disease
2004 Standout
Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation
2009 StandoutScience
SIGNALING PATHWAYS IN INTESTINAL DEVELOPMENT AND CANCER
2004
Liquid phase condensation in cell physiology and disease
2017 StandoutScience
LKB1 Regulates Lipid Oxidation During Exercise Independently of AMPK
2013
Works of Lina Udd being referenced
Impaired Gastric Gland Differentiation in Peutz-Jeghers Syndrome
2010
Suppression of Peutz—Jeghers polyposis by inhibition of cyclooxygenase-2
2004
Complexes between the LKB1 tumor suppressor, STRADα/β and MO25α/β are upstream kinases in the AMP-activated protein kinase cascade
2003
LKB1 is a master kinase that activates 13 kinases of the AMPK subfamily, including MARK/PAR‐1
2004
The LKB1 tumor suppressor kinase in human disease
2006