Citation Impact
Citing Papers
Generation of knock-in primary human T cells using Cas9 ribonucleoproteins
2015 StandoutNobel
CRISPR–Cas9 Structures and Mechanisms
2017 StandoutNobel
CRISPR/Cas9 in Genome Editing and Beyond
2016
High-throughput biochemical profiling reveals sequence determinants of dCas9 off-target binding and unbinding
2017 StandoutNobel
RNA-Guided Human Genome Engineering via Cas9
2013 StandoutScience
Optimized TAL effector nucleases (TALENs) for use in treatment of sickle cell disease
2012
The iCRISPR Platform for Rapid Genome Editing in Human Pluripotent Stem Cells
2014
Genome editing of the HIV co-receptors CCR5 and CXCR4 by CRISPR-Cas9 protects CD4+ T cells from HIV-1 infection
2017
Guide-bound structures of an RNA-targeting A-cleaving CRISPR–Cas13a enzyme
2017 StandoutNobel
Precise Correction of the Dystrophin Gene in Duchenne Muscular Dystrophy Patient Induced Pluripotent Stem Cells by TALEN and CRISPR-Cas9
2014 Nobel
Improved bi-allelic modification of a transcriptionally silent locus in patient-derived iPSC by Cas9 nickase
2016 StandoutNobel
Programmable editing of a target base in genomic DNA without double-stranded DNA cleavage
2016 StandoutNature
Germline development from human pluripotent stem cells toward disease modeling of infertility
2012 StandoutNobel
A guide to genome engineering with programmable nucleases
2014 Standout
Induced Pluripotent Stem Cells Meet Genome Editing
2016
Extracellular Vesicle RNA: A Universal Mediator of Microbial Communication?
2018 StandoutNobel
Genome editing of CXCR4 by CRISPR/cas9 confers cells resistant to HIV-1 infection
2015
New CRISPR–Cas systems from uncultivated microbes
2016 StandoutNatureNobel
The Use of Induced Pluripotent Stem Cells in Drug Development
2011 StandoutNobel
CRISPR–Cas9 genome engineering of primary CD4+ T cells for the interrogation of HIV–host factor interactions
2018 StandoutNobel
The biology and function of fibroblasts in cancer
2016 Standout
Highly efficient CD4+ T cell targeting and genetic recombination using engineered CD4+ cell-homing mRNA-LNPs
2021 StandoutNobel
Transient receptor potential channels: targeting pain at the source
2008 StandoutNobel
Temperature-Responsive Competitive Inhibition of CRISPR-Cas9
2018 StandoutNobel
Technical Challenges in Using Human Induced Pluripotent Stem Cells to Model Disease
2009
Targeted approaches for gene therapy and the emergence of engineered meganucleases
2009
Mutation of the mouse klotho gene leads to a syndrome resembling ageing
1997 StandoutNature
A Cas9 Ribonucleoprotein Platform for Functional Genetic Studies of HIV-Host Interactions in Primary Human T Cells
2016 StandoutNobel
Therapeutic genome editing: prospects and challenges
2015
Seamless gene correction of β-thalassemia mutations in patient-specific iPSCs using CRISPR/Cas9 and piggyBac
2014
Search-and-replace genome editing without double-strand breaks or donor DNA
2019 StandoutNature
CRISPR-Cas systems for editing, regulating and targeting genomes
2014 Standout
The CRISPR-Cas immune system: Biology, mechanisms and applications
2015
Sickle-cell disease
2010 Standout
Improved Modeling of Side-Chain–Base Interactions and Plasticity in Protein–DNA Interface Design
2012 StandoutNobel
Derivation and comparison of C57BL/6 embryonic stem cells to a widely used 129 embryonic stem cell line
2007
Applications of CRISPR technologies in research and beyond
2016 StandoutNobel
CRISPR/Cas9 cleavage of viral DNA efficiently suppresses hepatitis B virus
2015 StandoutNobel
A thermostable Cas9 with increased lifetime in human plasma
2017 StandoutNobel
Co-incident insertion enables high efficiency genome engineering in mouse embryonic stem cells
2016
Efficient Ablation of Genes in Human Hematopoietic Stem and Effector Cells using CRISPR/Cas9
2014
Engineering of monosized lipid-coated mesoporous silica nanoparticles for CRISPR delivery
2020 StandoutNobel
CRISPR-Based Technologies for the Manipulation of Eukaryotic Genomes
2016 Standout
Cornerstones of CRISPR–Cas in drug discovery and therapy
2016 StandoutNobel
Meganucleases and Other Tools for Targeted Genome Engineering: Perspectives and Challenges for Gene Therapy
2011
CasX enzymes comprise a distinct family of RNA-guided genome editors
2019 StandoutNatureNobel
A TALE nuclease architecture for efficient genome editing
2010 Standout
Topoisomerase I inhibitors: camptothecins and beyond
2006 Standout
Generation of Isogenic Human iPS Cell Line Precisely Corrected by Genome Editing Using the CRISPR/Cas9 System
2015
CCR5 Gene Disruption via Lentiviral Vectors Expressing Cas9 and Single Guided RNA Renders Cells Resistant to HIV-1 Infection
2014
Genome-editing Technologies for Gene and Cell Therapy
2016
Gene Editing in Human Pluripotent Stem Cells: Choosing the Correct Path.
2015
A prudent path forward for genomic engineering and germline gene modification
2015 StandoutScienceNobel
Inhibition of HIV-1 infection of primary CD4+ T-cells by gene editing of CCR5 using adenovirus-delivered CRISPR/Cas9
2015
The Free Radical Theory of Aging Matures
1998 Standout
Modeling hepatitis C virus infection using human induced pluripotent stem cells
2012 StandoutNobel
CRISPR-Cas: biology, mechanisms and relevance
2016 StandoutNobel
Reprogramming homing endonuclease specificity through computational design and directed evolution
2013 StandoutNobel
Positional Cloning of the Werner's Syndrome Gene
1996 Science
Population genetics of dinucleotide (dC-dA)n.(dG-dT)n polymorphisms in world populations.
1995
Aging, life span, and senescence
1998 StandoutNobel
Multiple Pathways of Recombination Induced by Double-Strand Breaks in Saccharomyces cerevisiae
1999 Standout
Global Patterns of Linkage Disequilibrium at the CD4 Locus and Modern Human Origins
1996 StandoutScienceNobel
Site-specific gene correction of a point mutation in human iPS cells derived from an adult patient with sickle cell disease
2011
Customizing the genome as therapy for the β-hemoglobinopathies
2016
Cas9 interrogates DNA in discrete steps modulated by mismatches and supercoiling
2020 StandoutNobel
Simultaneous precise editing of multiple genes in human cells
2019 StandoutNobel
A general strategy to construct small molecule biosensors in eukaryotes
2015 StandoutNobel
Neurons generated by direct conversion of fibroblasts reproduce synaptic phenotype caused by autism-associated neuroligin-3 mutation
2013 StandoutNobel
Targeted gene knock-in by homology-directed genome editing using Cas9 ribonucleoprotein and AAV donor delivery
2017 StandoutNobel
Material solutions for delivery of CRISPR/Cas-based genome editing tools: Current status and future outlook
2019
Surface Enhanced Raman Spectroscopy of Individual Rhodamine 6G Molecules on Large Ag Nanocrystals
1999 StandoutNobel
A deletion within the murine Werner syndrome helicase induces sensitivity to inhibitors of topoisomerase and loss of cellular proliferative capacity
1998
Genetic relationship of populations in China
1998 Standout
DNA Topoisomerases: Structure, Function, and Mechanism
2001 Standout
A Comparative View on Human Somatic Cell Sources for iPSC Generation
2014
Nontoxic nanopore electroporation for effective intracellular delivery of biological macromolecules
2019 StandoutNobel
Works of Lin Ye being referenced
Seamless modification of wild-type induced pluripotent stem cells to the natural CCR5Δ32 mutation confers resistance to HIV infection
2014
Induced pluripotent stem cells offer new approach to therapy in thalassemia and sickle cell anemia and option in prenatal diagnosis in genetic diseases
2009
Close Linkage of the Gene for Werner’s Syndrome to ANK1 and D8S87 on the Short Arm of Chromosome 8
1993
Narrowing the Position of the Werner Syndrome Locus by Homozygosity Analysis—Extension of Homozygosity Analysis
1996
Population variation in the dinucleotide repeat polymorphism at the D8S360 locus
1993
Correction of the sickle cell mutation in embryonic stem cells
2006
Sequence-Specific Correction of Genomic Hypoxanthine-Guanine Phosphoribosyl Transferase Mutations in Lymphoblasts by Small Fragment Homologous Replacement
2009
Blood Cell-Derived Induced Pluripotent Stem Cells Free of Reprogramming Factors Generated by Sendai Viral Vectors
2013