Standout Papers
Citation Impact
Citing Papers
Release of long-range tertiary interactions potentiates aggregation of natively unstructured α-synuclein
2005
A Gene Network Regulating Lysosomal Biogenesis and Function
2009 StandoutScience
α-Synuclein Blocks ER-Golgi Traffic and Rab1 Rescues Neuron Loss in Parkinson's Models
2006 Science
Ubiquitinated TDP-43 in Frontotemporal Lobar Degeneration and Amyotrophic Lateral Sclerosis
2006 StandoutScience
Pathological α-Synuclein Transmission Initiates Parkinson-like Neurodegeneration in Nontransgenic Mice
2012 StandoutScience
α-Synuclein Promotes SNARE-Complex Assembly in Vivo and in Vitro
2010 StandoutScienceNobel
Parkinson-like syndrome induced by continuous MPTP infusion: Convergent roles of the ubiquitin-proteasome system and α-synuclein
2005 StandoutNobel
PINK1-dependent recruitment of Parkin to mitochondria in mitophagy
2009 Standout
Astrocytic expression of Parkinson's disease-related A53T α-synuclein causes neurodegeneration in mice
2010
Altered Ribostasis: RNA-Protein Granules in Degenerative Disorders
2013
Genome-wide features of neuroendocrine regulation in Drosophila by the basic helix-loop-helix transcription factor DIMMED
2015 StandoutNobel
The synaptic pathology of α-synuclein aggregation in dementia with Lewy bodies, Parkinson’s disease and Parkinson’s disease dementia
2010
Induction of CNS α-synuclein pathology by fibrillar and non-amyloidogenic recombinant α-synuclein
2013
Genetic clues to the pathogenesis of Parkinson's disease
2004
Biomolecular condensates: organizers of cellular biochemistry
2017 Standout
Quality Control of Mitochondrial Proteostasis
2011
Mutant α-synuclein exacerbates age-related decrease of neurogenesis
2007
Mechanisms and Functional Implications of Adult Neurogenesis
2008 Standout
Origins and Effects of Extracellular α-synuclein: Implications in Parkinson’s Disease
2007
Generation of Isogenic Pluripotent Stem Cells Differing Exclusively at Two Early Onset Parkinson Point Mutations
2011
Nitrated α–Synuclein Immunity Accelerates Degeneration of Nigral Dopaminergic Neurons
2008
Mechanisms Underlying Inflammation in Neurodegeneration
2010 Standout
Cerebrospinal fluid biomarkers in Parkinson disease
2013
Soluble protein oligomers in neurodegeneration: lessons from the Alzheimer's amyloid β-peptide
2007 Standout
Molecular pathogenesis of Parkinson disease: insights from genetic studies
2009
The Lewy body in Parkinson's disease: Molecules implicated in the formation and degradation of α‐synuclein aggregates
2007
Direct Visualization of Asymmetric Adenine Nucleotide-Induced Conformational Changes in MutLα
2008 StandoutNobel
Genetics of Parkinson's disease
2005
Autophagy fights disease through cellular self-digestion
2008 StandoutNature
Lipid Rafts Mediate the Synaptic Localization of α-Synuclein
2004
The Co-chaperone Carboxyl Terminus of Hsp70-interacting Protein (CHIP) Mediates α-Synuclein Degradation Decisions between Proteasomal and Lysosomal Pathways
2005
High-resolution structure of the Shigella type-III secretion needle by solid-state NMR and cryo-electron microscopy
2014 StandoutNobel
Neurodegenerative disorders of protein aggregation
2003
Molecular Pathogenesis of Parkinson Disease
2005
Autophagy and neurodegeneration: when the cleaning crew goes on strike
2007
A Precipitating Role for Truncated α-Synuclein and the Proteasome in α-Synuclein Aggregation
2005
α-Synuclein propagates from mouse brain to grafted dopaminergic neurons and seeds aggregation in cultured human cells
2011
Parkinson's disease
2009 Standout
Priorities in Parkinson's disease research
2011
Nitric Oxide and Peroxynitrite in Health and Disease
2007 Standout
Clinical and biochemical correlates of insoluble α-synuclein in dementia with Lewy bodies
2006
100 years of Lewy pathology
2012
Decoding ALS: from genes to mechanism
2016 StandoutNature
Double Nicking by RNA-Guided CRISPR Cas9 for Enhanced Genome Editing Specificity
2013 Standout
Considerations and Challenges in Studying Liquid-Liquid Phase Separation and Biomolecular Condensates
2019 Standout
Gut Microbiota Regulate Motor Deficits and Neuroinflammation in a Model of Parkinson’s Disease
2016 Standout
On the mechanism of internalization of α‐synuclein into microglia: roles of ganglioside GM1 and lipid raft
2009
Association of DJ-1 and parkin mediated by pathogenic DJ-1 mutations and oxidative stress
2004
Genetics, environmental factors and the emerging role of epigenetics in neurodegenerative diseases
2008
PINK, PANK, or PARK? A clinicians' guide to familial parkinsonism
2004
Parkinson's disease
2015 Standout
Prediction of “Aggregation-prone” and “Aggregation-susceptible” Regions in Proteins Associated with Neurodegenerative Diseases
2005
Natural RNA circles function as efficient microRNA sponges
2013 StandoutNature
Autophagy in the Pathogenesis of Disease
2008 Standout
Ubiquitin–proteasome system and Parkinson's disease
2006
Epidemiological, clinical, and genetic characteristics of early-onset parkinsonism
2006
α-Synuclein Cooperates with CSPα in Preventing Neurodegeneration
2005 StandoutNobel
Update on the genetics of Parkinson's disease
2007
Autophagy in Human Health and Disease
2013 Standout
The neuropathology of genetic Parkinson's disease
2012
Immunological features of α‐synuclein in Parkinson's disease
2008
Advances in the genetics of Parkinson disease
2013
Genome engineering using the CRISPR-Cas9 system
2013 Standout
Alzheimer's disease
2016 Standout
Characterization of antibodies that selectively detect α-synuclein in pathological inclusions
2008
Lewy body Parkinson's disease in a large pedigree with 77Parkin mutation carriers
2005
One-Step Generation of Mice Carrying Mutations in Multiple Genes by CRISPR/Cas-Mediated Genome Engineering
2013 Standout
Increased Expression of α-Synuclein Reduces Neurotransmitter Release by Inhibiting Synaptic Vesicle Reclustering after Endocytosis
2010
Loss of autophagy in the central nervous system causes neurodegeneration in mice
2006 StandoutNature
Mitochondrial dysfunction and oxidative stress in neurodegenerative diseases
2006 StandoutNature
A Liquid-to-Solid Phase Transition of the ALS Protein FUS Accelerated by Disease Mutation
2015 Standout
Calcium(II) selectively induces α‐synuclein annular oligomers via interaction with the C‐terminal domain
2004
The Amyloid State of Proteins in Human Diseases
2012 Standout
NMR mapping of copper binding sites in alpha-synuclein
2005
Neuroinflammation and Oxidation/Nitration of α-Synuclein Linked to Dopaminergic Neurodegeneration
2008
Repertoires of Autophagy in the Pathogenesis of Ocular Diseases
2015 Standout
Systematic Mutagenesis of α-Synuclein Reveals Distinct Sequence Requirements for Physiological and Pathological Activities
2012 StandoutNobel
Prion-like spreading of pathological α-synuclein in brain
2013
Glial dysfunction in the pathogenesis of α-synucleinopathies: emerging concepts
2011
Neurodegenerative diseases: a decade of discoveries paves the way for therapeutic breakthroughs
2004
Cell-free Formation of RNA Granules: Low Complexity Sequence Domains Form Dynamic Fibers within Hydrogels
2012 Standout
Glia and alpha-synuclein in neurodegeneration: A complex interaction
2015
A common LRRK2 mutation in idiopathic Parkinson's disease
2005 Standout
Genetics of Parkinsonʼs disease
2005
Parkinson's Disease Patient-Derived Induced Pluripotent Stem Cells Free of Viral Reprogramming Factors
2009 Standout
Pathogenesis of synaptic degeneration in Alzheimer's disease and Lewy body disease
2014
Solid-State NMR Spectroscopy of Proteins
2013
Recent advances into the understanding of mitochondrial fission
2012
Are synucleinopathies prion-like disorders?
2010
Monogenic Parkinson's disease and parkinsonism: Clinical phenotypes and frequencies of known mutations
2013
Inflammasomes: mechanism of action, role in disease, and therapeutics
2015 Standout
Phase Separation by Low Complexity Domains Promotes Stress Granule Assembly and Drives Pathological Fibrillization
2015 Standout
Triggering of Inflammasome by Aggregated α–Synuclein, an Inflammatory Response in Synucleinopathies
2013
Different Species of α-Synuclein Oligomers Induce Calcium Influx and Seeding
2007
The genetics of P arkinson's disease: Progress and therapeutic implications
2013
Protein Misfolding, Functional Amyloid, and Human Disease
2006 Standout
γ‐Synuclein and the progression of cancer
2007
Native α-synuclein induces clustering of synaptic-vesicle mimics via binding to phospholipids and synaptobrevin-2/VAMP2
2013 StandoutNobel
Neuroimmunological Processes in Parkinson’s Disease and their Relation to α-Synuclein: Microglia as the Referee between Neuronal Processes and Peripheral Immunity
2013
Development of an Ion Mobility Quadrupole Time of Flight Mass Spectrometer
2008 StandoutNobel
Intrinsic disorder in proteins associated with neurodegenerative diseases
2009
What Genetics Tells us About the Causes and Mechanisms of Parkinson's Disease
2011
Mitochondrial Fission, Fusion, and Stress
2012 StandoutScience
Copper Homeostasis and Neurodegenerative Disorders (Alzheimer's, Prion, and Parkinson's Diseases and Amyotrophic Lateral Sclerosis)
2006 Standout
Chromone: A Valid Scaffold in Medicinal Chemistry
2014 Standout
Repression of α-synuclein expression and toxicity by microRNA-7
2009
Protein Expression in a Drosophila Model of Parkinson's Disease
2006
Classification of Intrinsically Disordered Regions and Proteins
2014 Standout
Double-knockout mice for α- and β-synucleins: Effect on synaptic functions
2004 StandoutNobel
How neuroinflammation contributes to neurodegeneration
2016 StandoutScience
Aggregated α‐synuclein activates microglia: a process leading to disease progression in Parkinson's disease
2005
In vivo demonstration that α-synuclein oligomers are toxic
2011
Functional Anthology of Intrinsic Disorder. 3. Ligands, Post-Translational Modifications, and Diseases Associated with Intrinsically Disordered Proteins
2007
The 3D profile method for identifying fibril-forming segments of proteins
2006 StandoutNobel
Mitochondrial Dysfunction and Oxidative Damage in parkin-deficient Mice
2004
MOLECULAR PATHOPHYSIOLOGY OF PARKINSON'S DISEASE
2005
Parkinson's Disease: Genetics and Pathogenesis
2011
Metals in Neurobiology: Probing Their Chemistry and Biology with Molecular Imaging
2008 Standout
α‐Synuclein oligomers and clinical implications for Parkinson disease
2012
Works of Lídice Vidal being referenced
Steele‐Richardson‐Olszewski syndrome in a patient with a single C212Y mutation in the parkin protein
2002
The new mutation, E46K, of α‐synuclein causes parkinson and Lewy body dementia
2003 Standout
Molecular Findings in Familial Parkinson Disease in Spain
2002