Citation Impact
Citing Papers
Structure-Based Optimization Strategies for G Protein-Coupled Receptor (GPCR) Allosteric Modulators: A Case Study from Analyses of New Metabotropic Glutamate Receptor 5 (mGlu 5 ) X-ray Structures
2018
Computational design of soluble and functional membrane protein analogues
2024 StandoutNatureNobel
Ionotropic and metabotropic glutamate receptor structure and pharmacology
2005
An efficient and convenient Cu(OAc)2/air mediated oxidative coupling of azoles via C–H activation
2009
Palladium complexes of abnormal N-heterocyclic carbenes as precatalysts for the much preferred Cu-free and amine-free Sonogashira coupling in air in a mixed-aqueous medium
2009
Copper-free Sonogashira cross-coupling reaction catalyzed by polymer-supported N-heterocyclic carbene palladium complex
2007
RIM1α and Interacting Proteins Involved in Presynaptic Plasticity Mediate Prepulse Inhibition and Additional Behaviors Linked to Schizophrenia
2010 StandoutNobel
Discovery of heterobicyclic templates for novel metabotropic glutamate receptor subtype 5 antagonists
2007
The Human Obesity Gene Map: The 2005 Update
2006
Mechanochemistry: opportunities for new and cleaner synthesis
2011 Standout
mGluR5 and NMDA Receptors Drive the Experience- and Activity-Dependent NMDA Receptor NR2B to NR2A Subunit Switch
2011
Blockade of glutamate mGlu5 receptors in a rat model of neuropathic pain prevents early over-expression of pro-apoptotic genes and morphological changes in dorsal horn lamina II
2004
The modified Geller–Seifter test in rats was insensitive to GABAB receptor positive modulation or blockade, or 5-HT1A receptor activation
2009
Trends in GPCR drug discovery: new agents, targets and indications
2017 Standout
Stepwise aromatic nucleophilic substitution in continuous flow. Synthesis of an unsymmetrically substituted 3,5-diamino-benzonitrile library
2010
Glutamate and Schizophrenia: Phencyclidine, N‐Methyl‐d‐Aspartate Receptors, and Dopamine–Glutamate Interactions
2007
Molecular Dynamics Simulation for All
2018 Standout
Palladium(II)‐Catalyzed CH Activation/CC Cross‐Coupling Reactions: Versatility and Practicality
2009 Standout
Highly Convenient Amine‐Free Sonogashira Coupling in Air in a Polar Mixed Aqueous Medium by trans‐ and cis‐[(NHC)2PdX2] (X=Cl, Br) Complexes of N/O‐Functionalized N‐Heterocyclic Carbenes
2008
Recent advances in the transition metal-catalyzed twofold oxidative C–H bond activation strategy for C–C and C–N bond formation
2011 Standout
Ligand-specific regulation of the extracellular surface of a G-protein-coupled receptor
2010 StandoutNatureNobel
Molecular Mechanisms of Depression: Perspectives on New Treatment Strategies
2013 Standout
Catalytic Functionalization of Indoles in a New Dimension
2009 Standout
Novelty and Anxiolytic Drugs Dissociate Two Components of Hippocampal Theta in Behaving Rats
2013 StandoutNobel
RGD modified polymers: biomaterials for stimulated cell adhesion and beyond
2003 Standout
Allosteric modulators of GPCRs: a novel approach for the treatment of CNS disorders
2008
The structure and function of G-protein-coupled receptors
2009 StandoutNatureNobel
Fascinating frontiers of N/O-functionalized N-heterocyclic carbene chemistry: from chemical catalysis to biomedical applications
2010
Physiology and Pathophysiology of Purinergic Neurotransmission
2007 Standout
Iron catalysed direct alkylation of amines with alcohols
2014 StandoutNobel
N-Heterocyclic carbene (NHC) ligands and palladium in homogeneous cross-coupling catalysis: a perfect union
2011 Standout
Potential antidepressant-like effect of MTEP, a potent and highly selective mGluR5 antagonist
2005
Chronic Back Pain Is Associated with Decreased Prefrontal and Thalamic Gray Matter Density
2004 Standout
Effects of adenosine A1, dopamine D1 and metabotropic glutamate 5 receptors-modulating agents on locomotion of the reserpinised rats
2004
Biaryl Phosphane Ligands in Palladium‐Catalyzed Amination
2008 Standout
Transition‐Metal‐Catalyzed Direct Arylation of (Hetero)Arenes by CH Bond Cleavage
2009 Standout
Catalytic CC, CN, and CO Ullmann‐Type Coupling Reactions
2009 Standout
Genetics of Food Intake Self-Regulation in Childhood: Literature Review and Research Opportunities
2013 Standout
Versatile tools in the construction of substituted 2,2′-bipyridines—cross-coupling reactions with tin, zinc and boron compounds
2008
NMDA receptor subunit diversity: impact on receptor properties, synaptic plasticity and disease
2013 Standout
Recent advances in Sonogashira reactions
2011 Standout
Iron Catalysis in Organic Synthesis
2015 Standout
3d Transition Metals for C–H Activation
2018 Standout
Sequential and domino Sonogashira coupling: Efficient tools for the synthesis of diarylalkynes
2005
Development of allosteric modulators of GPCRs for treatment of CNS disorders
2013
Bond Formations between Two Nucleophiles: Transition Metal Catalyzed Oxidative Cross-Coupling Reactions
2011 Standout
The nickel-catalyzed Sonogashira–Hagihara reaction
2003
A revisit to the Hantzsch reaction: Unexpected products beyond 1,4-dihydropyridines
2009
A novel strategy for the synthesis of 2-arylpyridines using one-pot 6π-azaelectrocyclization
2008
Discovery of Molecular Switches That Modulate Modes of Metabotropic Glutamate Receptor Subtype 5 (mGlu5) Pharmacology in Vitro and in Vivo within a Series of Functionalized, Regioisomeric 2- and 5-(Phenylethynyl)pyrimidines
2009
Cross‐Coupling Reactions on Azoles with Two and More Heteroatoms
2006
Efficient and Regioselective Halogenations of 2-Amino-1,3-thiazoles with Copper Salts
2009
Oxidative Coupling between Two Hydrocarbons: An Update of Recent C–H Functionalizations
2015 Standout
New Palladium‐Catalyzed Domino Reaction with Intramolecular Ring Closure of an N‐(2‐Chloro‐3‐heteroaryl)arylamide: First Synthesis of Oxazolo[4,5‐b]pyrazines
2014
The Hitchhiker’s Guide to Flow Chemistry
2017 Standout
Synthesis and Pharmacological Evaluation of Phenylethynyl[1,2,4]methyltriazines as Analogues of 3-Methyl-6-(phenylethynyl)pyridine
2007
Biarylphosphanliganden in der palladiumkatalysierten Aminierung
2008
Palladium-Catalyzed C–H Bond Direct Alkynylation of 5-Membered Heteroarenes: A Well-Defined Synthetic Route to Azole Derivatives Containing Two Different Alkynyl Groups
2012
A new, efficient, and inexpensive copper(II)/salicylic acid complex catalyzed Sonogashira-type cross-coupling of haloarenes and iodoheteroarenes with terminal alkynes
2010
Facile Synthesis of 2-Alkynyl Buta-1,3-dienes via Sonogashira Cross-Coupling Methodology
2005
The Sonogashira Reaction: A Booming Methodology in Synthetic Organic Chemistry
2007 Standout
Next Generation of Fluorine-Containing Pharmaceuticals, Compounds Currently in Phase II–III Clinical Trials of Major Pharmaceutical Companies: New Structural Trends and Therapeutic Areas
2016 Standout
Dppc+PF6−–PdCl2–[bmim][PF6]–a copper‐free recyclable catalytic system for Sonogashira coupling reaction
2007
Regioselective synthesis of cytotoxic 4-(1-alkynyl)-substituted 2-(5H)-furanones
2003
Sonogashira–Hagihara Coupling towards Diaryl Alkynes Catalyzed by FeCl3⋅6 H2O/Cationic 2,2'‐Bipyridyl
2012
Occurrence, Biogenesis, and Synthesis of Biologically Active Carbazole Alkaloids
2012 Standout
Carboxylate-Assisted Transition-Metal-Catalyzed C−H Bond Functionalizations: Mechanism and Scope
2011 Standout
Highly Convenient, Clean, Fast, and Reliable Sonogashira Coupling Reactions Promoted by Aminophosphine‐Based Pincer Complexes of Palladium Performed under Additive‐ and Amine‐Free Reaction Conditions
2009
Palladium-Catalyzed Suzuki−Miyaura Cross-Coupling Reactions Employing Dialkylbiaryl Phosphine Ligands
2008 Standout
Palladium-Catalyzed Transformations of Alkyl C–H Bonds
2016 Standout
N-Heterocyclic Carbenes in Late Transition Metal Catalysis
2009 Standout
Ligand-free copper(Ι)-catalyzed Sonogashira-type coupling of arylboronic acids with terminal alkynes
2009
Catalytic Dehydrogenative Cross-Coupling: Forming Carbon−Carbon Bonds by Oxidizing Two Carbon−Hydrogen Bonds
2011 Standout
Aryl−Aryl Bond Formation by Transition-Metal-Catalyzed Direct Arylation
2007 Standout
Substituent Effects ofN-(1,3-Diphenyl-1H-pyrazol-5-yl)benzamides on Positive Allosteric Modulation of the Metabotropic Glutamate-5 Receptor in Rat Cortical Astrocytes
2006
Hydrogen Autotransfer in the N-Alkylation of Amines and Related Compounds using Alcohols and Amines as Electrophiles
2009 Standout
Novel pyridine‐bis(ferrocene‐isoxazole) ligand: synthesis and application to palladium‐catalyzed Sonogashira cross‐coupling reactions under copper‐ and phosphine‐free conditions
2008
Reversible Photocontrol of Biological Systems by the Incorporation of Molecular Photoswitches
2013 StandoutNobel
Aerobic Copper-Catalyzed Organic Reactions
2013 Standout
Alkyne Elementometalation−Pd-Catalyzed Cross-Coupling. Toward Synthesis of All Conceivable Types of Acyclic Alkenes in High Yields, Efficiently, Selectively, Economically, and Safely: “Green” Way
2010 StandoutNobel
Organic Reactions in Aqueous Media with a Focus on Carbon−Carbon Bond Formations: A Decade Update
2005 Standout
Large-Scale Applications of Transition Metal-Catalyzed Couplings for the Synthesis of Pharmaceuticals
2011 Standout
Regioselective cross-coupling reactions of multiple halogenated nitrogen-, oxygen-, and sulfur-containing heterocycles
2004
Applications of Palladium-Catalyzed C–N Cross-Coupling Reactions
2016 Standout
Analogues of oxytocin with an oxime bridge using chemoselectively addressable building blocks
1996
Formation of a hetero[3]rotaxane by a dynamic component-swapping strategy
2014 StandoutNobel
Polystyrene‐supported Palladium(II) Ethylenediamine Complex: A Recyclable Catalyst for the Syntheses of 2‐Benzyl‐imidazo[2,1‐b][1,3]benzothiazoles by Sonogashira Reaction
2009
Visible‐Light Photocatalysis: Does It Make a Difference in Organic Synthesis?
2018 Standout
Transition Metal-Catalyzed C–H Amination: Scope, Mechanism, and Applications
2017 Standout
From 2000 to Mid-2010: A Fruitful Decade for the Synthesis of Pyrazoles
2011 Standout
Application of recoverable nanosized palladium(0) catalyst in Sonogashira reaction
2005
An Amine‐, Copper‐ and Phosphine‐Free Sonogashira Coupling Reaction Catalyzed by Immobilization of Palladium in Organic–Inorganic Hybrid Materials
2006
Synthesis and Structure−Activity Relationships of 3-[(2-Methyl-1,3-thiazol-4-yl)ethynyl]pyridine Analogues as Potent, Noncompetitive Metabotropic Glutamate Receptor Subtype 5 Antagonists; Search for Cocaine Medications
2006
Comprehensive Experimental Study of N-Heterocyclic π-Stacking Interactions of Neutral and Cationic Pyridines
2013
Design, Synthesis, and Structure−Activity Relationships of Novel Bicyclic Azole-amines as Negative Allosteric Modulators of Metabotropic Glutamate Receptor 5
2010
Silver-Catalyzed Csp−H and Csp−Si Bond Transformations and Related Processes
2008
Metal-Free Multicomponent Syntheses of Pyridines
2014 Standout
Works of Lida Tehrani being referenced
The Behavioral Profile of the Potent and Selective mGlu5 Receptor Antagonist 3-[(2-methyl-1,3-thiazol-4-yl)ethynyl]pyridine (MTEP) in Rodent Models of Anxiety
2004
2-{2-[3-(Pyridin-3-yloxy)phenyl]-2H-tetrazol-5-yl}pyridine: a highly potent, orally active, metabotropic glutamate subtype 5 (mGlu5) receptor antagonist
2004
5-[(2-Methyl-1,3-thiazol-4-yl)ethynyl]-2,3′-bipyridine: a highly potent, orally active metabotropic glutamate subtype 5 (mGlu5) receptor antagonist with anxiolytic activity
2004
3-[Substituted]-5-(5-pyridin-2-yl-2H-tetrazol-2-yl)benzonitriles: Identification of highly potent and selective metabotropic glutamate subtype 5 receptor antagonists
2005
[3H]-Methoxymethyl-MTEP and [3H]-Methoxy-PEPy: potent and selective radioligands for the metabotropic glutamate subtype 5 (mGlu5) receptor
2003
Metabotropic Glutamate Receptor mGlu5 Is a Mediator of Appetite and Energy Balance in Rats and Mice
2005
[3H]Methoxymethyl-3-[(2-methyl-1,3-thiazol-4-yl)ethynyl]pyridine Binding to Metabotropic Glutamate Receptor Subtype 5 in Rodent Brain: In Vitro and in Vivo Characterization
2002
Discovery of highly potent, selective, orally bioavailable, metabotropic glutamate subtype 5 (mGlu5) receptor antagonists devoid of cytochrome P450 1A2 inhibitory activity
2004
Synthesis and physicochemical characterization of the lanthionine analog of somatostatin[1?14]
1994
3-[(2-Methyl-1,3-thiazol-4-yl)ethynyl]- pyridine: A Potent and Highly Selective Metabotropic Glutamate Subtype 5 Receptor Antagonist with Anxiolytic Activity
2002