Citation Impact
Citing Papers
Neurotoxic protein expression reveals connections between the circadian clock and mating behavior in Drosophila
2006 StandoutNobel
Prospective identification of tumorigenic breast cancer cells
2003 Standout
TFEB Links Autophagy to Lysosomal Biogenesis
2011 StandoutScience
Phosphorylation of ULK1 (hATG1) by AMP-Activated Protein Kinase Connects Energy Sensing to Mitophagy
2010 StandoutScience
Impairment of starvation-induced and constitutive autophagy in Atg7 -deficient mice
2005 StandoutNobel
Pathological α-Synuclein Transmission Initiates Parkinson-like Neurodegeneration in Nontransgenic Mice
2012 StandoutScience
Programmed cell death 1 ligand 1 and tumor-infiltrating CD8 + T lymphocytes are prognostic factors of human ovarian cancer
2007 StandoutNobel
Histone deacetylase inhibitors prevent oxidative neuronal death independent of expanded polyglutamine repeats via an Sp1-dependent pathway
2003
AMPK regulates energy expenditure by modulating NAD+ metabolism and SIRT1 activity
2009 StandoutNature
Mutant huntingtin directly increases susceptibility of mitochondria to the calcium-induced permeability transition and cytochrome c release
2004
Inflammation and cancer
2002 StandoutNature
The Ubiquitin Proteasome System in Neurodegenerative Diseases
2003 StandoutNobel
Are Huntington’s and polyglutamine-based ataxias proteasome storage diseases?
2003
Tumor formation and inactivation of RIZ1, an Rb-binding member of a nuclear protein–methyltransferase superfamily
2001
DNA vaccine with α-galactosylceramide at prime phase enhances anti-tumor immunity after boosting with antigen-expressing dendritic cells
2010
Loss of normal huntingtin function: new developments in Huntington's disease research
2001
Excitotoxic Neuronal Death and the Pathogenesis of Huntington's Disease
2008
Prolyl 4-hydroxylase activity-responsive transcription factors: From hydroxylation to gene expression and neuroprotection
2007
Intranasal immunization with synthetic peptides corresponding to the E6 and E7 oncoproteins of human papillomavirus type 16 induces systemic and mucosal cellular immune responses and tumor protection
2007
Axon degeneration mechanisms: commonality amid diversity
2005
Dramatic tissue-specific mutation length increases are an early molecular event in Huntington disease pathogenesis
2003
A cell-based screen for drugs to treat Huntington's disease
2004
Inclusion body formation reduces levels of mutant huntingtin and the risk of neuronal death
2004 StandoutNature
A role for mitochondria in NLRP3 inflammasome activation
2010 StandoutNature
Cancer immunotherapy: breaking the barriers to harvest the crop
2004 StandoutNobel
Altered proteasomal function due to the expression of polyglutamine-expanded truncated N-terminal huntingtin induces apoptosis by caspase activation through mitochondrial cytochrome c release
2001
Autophagy fights disease through cellular self-digestion
2008 StandoutNature
Mismatch repair gene Msh2 modifies the timing of early disease in HdhQ111 striatum
2003
The Human Transcription Factors
2018 Standout
Nature and cause of mitochondrial dysfunction in Huntington’s disease: focusing on huntingtin and the striatum
2010
Autophagy: Renovation of Cells and Tissues
2011 Standout
Induction of Autophagy in Axonal Dystrophy and Degeneration
2006
cAMP oscillations and retinal activity are permissive for ephrin signaling during the establishment of the retinotopic map
2007 StandoutNobel
Knockdown of DISC1 by In Utero Gene Transfer Disturbs Postnatal Dopaminergic Maturation in the Frontal Cortex and Leads to Adult Behavioral Deficits
2010
Biological Functions of Autophagy Genes: A Disease Perspective
2019 Standout
Dramatic mutation instability in HD mouse striatum: does polyglutamine load contribute to cell-specific vulnerability in Huntington's disease?
2000
Decoding ALS: from genes to mechanism
2016 StandoutNature
p53 Mediates Cellular Dysfunction and Behavioral Abnormalities in Huntington’s Disease
2005
mTOR Signaling in Growth, Metabolism, and Disease
2017 Standout
Blinded by the Light: The Growing Complexity of p53
2009 Standout
Mitochondrial Respiration and ATP Production Are Significantly Impaired in Striatal Cells Expressing Mutant Huntingtin
2005
Optimization of a self antigen for presentation of multiple epitopes in cancer immunity
2006
Glial and neuronal expression of polyglutamine proteins induce behavioral changes and aggregate formation in Drosophila
2004
Minireview: The role of the vacuolar ATPase in nematodes
2011
Rethinking schizophrenia
2010 StandoutNature
Cell death triggered by polyglutamine-expanded huntingtin in a neuronal cell line is associated with degradation of CREB-binding protein
2003
Huntingtin Is Present in the Nucleus, Interacts with the Transcriptional Corepressor C-terminal Binding Protein, and Represses Transcription
2002
Striatal Expression of a Calmodulin Fragment Improved Motor Function, Weight Loss, and Neuropathology in the R6/2 Mouse Model of Huntington's Disease
2009
Polyglutamine Pathogenesis
2002
The Charcot–Marie–Tooth type 2A gene product, Mfn2, up-regulates fuel oxidation through expression of OXPHOS system
2005
Hereditary Colorectal Cancer
2003 Standout
Methods in Mammalian Autophagy Research
2010 Standout
Autophagy and Aging
2011 Standout
Loss of autophagy in the central nervous system causes neurodegeneration in mice
2006 StandoutNature
Mitochondrial dysfunction and oxidative stress in neurodegenerative diseases
2006 StandoutNature
Spinning molecular immunology into successful immunotherapy
2002
The PtdIns(3,4)P2 phosphatase INPP4A is a suppressor of excitotoxic neuronal death
2010 StandoutNatureNobel
Polyglutamine Expansion, Protein Aggregation, Proteasome Activity, and Neural Survival
2002
Subnuclear segregation of genes and core promoter factors in myogenesis
2011 StandoutNobel
AKT/PKB Signaling: Navigating the Network
2017 Standout
Repertoires of Autophagy in the Pathogenesis of Ocular Diseases
2015 Standout
In Vitro Analysis of Huntingtin-Mediated Transcriptional Repression Reveals Multiple Transcription Factor Targets
2005
The Hallmarks of Aging
2013 Standout
PRDI-BF1 recruits the histone H3 methyltransferase G9a in transcriptional silencing
2004
Expanded polyglutamine stretches form an ‘aggresome’
2002
Polyglutamine aggregation behavior in vitro supports a recruitment mechanism of cytotoxicity
2001
Keep Your Fingers Off My DNA: Protein–Protein Interactions Mediated by C2H2 Zinc Finger Domains
2008
The epigenetics of aging and neurodegeneration
2015
Structural Bases of Desensitization in AMPA Receptor-Auxiliary Subunit Complexes
2017 StandoutNobel
Selective Neuronal Degeneration in Huntington's Disease
2006
Transcriptional abnormalities in Huntington disease
2003
Selective Inhibition of Hypoxia-Inducible Factor (HIF) Prolyl-Hydroxylase 1 Mediates Neuroprotection against Normoxic Oxidative Death via HIF- and CREB-Independent Pathways
2009 StandoutNobel
Pivotal role of oligomerization in expanded polyglutamine neurodegenerative disorders
2003 Nature
Transcriptional changes in Huntington disease identified using genome-wide expression profiling and cross-platform analysis
2010
Molecular pathways to neurodegeneration
2004
Involvement of the MKK6-p38γ Cascade in γ-Radiation-Induced Cell Cycle Arrest
2000
Mechanisms of transcriptional dysregulation in Huntington's disease
2003
Cross-presentation of glycolipid from tumor cells loaded with α-galactosylceramide leads to potent and long-lived T cell–mediated immunity via dendritic cells
2007 StandoutNobel
Mechanisms of cell death in polyglutamine expansion diseases
2003
Essential role for autophagy protein Atg7 in the maintenance of axonal homeostasis and the prevention of axonal degeneration
2007
A cell-based assay for aggregation inhibitors as therapeutics of polyglutamine-repeat disease and validation in Drosophila
2003
Lysosomal activity regulatesCaenorhabditis elegansmitochondrial dynamics through vitamin B12 metabolism
2020 StandoutNobel
Rb-Mediated Heterochromatin Formation and Silencing of E2F Target Genes during Cellular Senescence
2003 Standout
Membrane proteomics of phagosomes suggests a connection to autophagy
2008 StandoutNobel
Fluorescence Lifetime Measurements and Biological Imaging
2010 Standout
DNA Mismatch Repair: Functions and Mechanisms
2005 StandoutNobel
Histone H3 lysine 9 di-methylation as an epigenetic signature of the interferon response
2012 StandoutNobel
How neuroinflammation contributes to neurodegeneration
2016 StandoutScience
Unique potential of 4-1BB agonist antibody to promote durable regression of HPV + tumors when combined with an E6/E7 peptide vaccine
2015 StandoutNobel
Candidate tumor suppressor RIZ is frequently involved in colorectal carcinogenesis
2000
AXON RETRACTION AND DEGENERATION IN DEVELOPMENT AND DISEASE
2005
Huntingtin forms toxic NH2-terminal fragment complexes that are promoted by the age-dependent decrease in proteasome activity
2003
Axonal Self-Destruction and Neurodegeneration
2002 Science
Immunotherapy: Bewitched, Bothered, and Bewildered No More
2004 StandoutScienceNobel
Extrahelical (CAG)/(CTG) triplet repeat elements support proliferating cell nuclear antigen loading and MutLα endonuclease activation
2013 StandoutNobel
Expanded CAG repeats in exon 1 of the Huntington's disease gene stimulate dopamine-mediated striatal neuron autophagy and degeneration
2001
Nitric oxide prevents axonal degeneration by inducing HIF-1–dependent expression of erythropoietin
2011 StandoutNobel
Disruption of Axonal Transport by Loss of Huntingtin or Expression of Pathogenic PolyQ Proteins in Drosophila
2003
Mechanisms of acute axonal degeneration in the optic nerve in vivo
2010
Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation
2009 StandoutScience
Molecular Mechanisms of Mammalian DNA Repair and the DNA Damage Checkpoints
2004 StandoutNobel
Autophagy in Health and Disease: A Double-Edged Sword
2004 StandoutScience
Works of Li He being referenced
Amino-terminal fragments of mutant huntingtin show selective accumulation in striatal neurons and synaptic toxicity
2000
A vacuolar-type proton (H+) translocating ATPase α subunit encoded by the Hc-vha-6 gene of Haemonchus contortus
2010
Huntingtin Aggregate-Associated Axonal Degeneration is an Early Pathological Event in Huntington's Disease Mice
2001
Mutant Huntingtin Causes Context-Dependent Neurodegeneration in Mice with Huntington's Disease
2003
RIZ1, but not the alternative RIZ2 product of the same gene, is underexpressed in breast cancer, and forced RIZ1 expression causes G2-M cell cycle arrest and/or apoptosis.
1998
Interaction of Huntington Disease Protein with Transcriptional Activator Sp1
2002
Cancer immunotherapy using a DNA vaccine encoding the translocation domain of a bacterial toxin linked to a tumor antigen.
2001
Cellular Defects and Altered Gene Expression in PC12 Cells Stably Expressing Mutant Huntingtin
1999