Standout Papers
Citation Impact
Citing Papers
Phase separation of signaling molecules promotes T cell receptor signal transduction
2016 Science
Protein interaction networks revealed by proteome coevolution
2019 StandoutScienceNobel
Imaging Intracellular Fluorescent Proteins at Nanometer Resolution
2006 StandoutScienceNobel
Single Reconstituted Neuronal SNARE Complexes Zipper in Three Distinct Stages
2012 StandoutScienceNobel
SNARE Function Analyzed in Synaptobrevin/VAMP Knockout Mice
2001 StandoutScienceNobel
Functional Genomic Analysis of RNA Interference in C. elegans
2005 StandoutScienceNobel
Computational Thermostabilization of an Enzyme
2005 StandoutScienceNobel
Computational design of ligand binding is not a solved problem
2009
De novo design of modular and tunable protein biosensors
2021 StandoutNatureNobel
Single-crystal x-ray diffraction structures of covalent organic frameworks
2018 StandoutScienceNobel
Protein Conformational Switches: From Nature to Design
2012
Functional study of the rat cortical microcircuitry with voltage- sensitive dye imaging of neocortical slices
1997
Functional architecture of an intracellular membrane t-SNARE
2000 StandoutNatureNobel
Self-assembled nanoscale biosensors based on quantum dot FRET donors
2003
CCD imaging of the electrical activity in the leech nervous system
1996
Nonlinear magic: multiphoton microscopy in the biosciences
2003 Standout
Voltage sensing by fluorescence resonance energy transfer in single cells
1995 StandoutNobel
Discoveries in structure and physiology of mechanically activated ion channels
2020 StandoutNatureNobel
Metabotropic receptor activation, desensitization and sequestration—I: modelling calcium and inositol 1,4,5-trisphosphate dynamics following receptor activation
2003
Spectra of voltage-sensitive fluorescence of styryl-dye in neuron membrane
1991
Fluorescence Lifetime Imaging Provides Enhanced Contrast when Imaging the Phase-Sensitive Dye di-4-ANEPPDHQ in Model Membranes and Live Cells
2006
Cytoscape: A Software Environment for Integrated Models of Biomolecular Interaction Networks
2003 Standout
The capsaicin receptor: a heat-activated ion channel in the pain pathway
1997 StandoutNatureNobel
Imaging of cancer cells by multiphoton microscopy using gold nanoparticles and fluorescent dyes
2008
Improved indicators of cell membrane potential that use fluorescence resonance energy transfer
1997 StandoutNobel
Navigating transdermal diffusion with multiphoton fluorescence lifetime imaging
2008
Electrical signals control wound healing through phosphatidylinositol-3-OH kinase-γ and PTEN
2006 StandoutNatureNobel
Monitoring Biophysical Properties of Lipid Membranes by Environment-Sensitive Fluorescent Probes
2009
Fluorescence Quenching of Dye Molecules near Gold Nanoparticles: Radiative and Nonradiative Effects
2002
Pattern recognition computation using action potential timing for stimulus representation
1995 StandoutNatureNobel
Timing of neurotransmission at fast synapses in the mammalian brain
1996 Nature
The statistical mechanics of complex signaling networks: nerve growth factor signaling
2004
Visualization of Membrane Rafts Using a Perylene Monoimide Derivative and Fluorescence Lifetime Imaging
2007
RNA phase transitions in repeat expansion disorders
2017 Nature
The Perseus computational platform for comprehensive analysis of (prote)omics data
2016 Standout
The small GTPase Ran: interpreting the signs
2003
Importin Beta
2004
Synaptotagmin I functions as a calcium regulator of release probability
2001 StandoutNatureNobel
Sensing voltage across lipid membranes
2008 Nature
TRPV1 structures in distinct conformations reveal activation mechanisms
2013 StandoutNatureNobel
Structure of the TRPV1 ion channel determined by electron cryo-microscopy
2013 StandoutNatureNobel
De novo design of bioactive protein switches
2019 StandoutNatureNobel
β2-Adrenergic Receptor Signaling and Desensitization Elucidated by Quantitative Modeling of Real Time cAMP Dynamics
2007 StandoutNobel
Fluorescence ratio imaging of cyclic AMP in single cells
1991 StandoutNatureNobel
Molecular–functional imaging of cancer: to image and imagine
2007
Programmed population control by cell–cell communication and regulated killing
2004 StandoutNatureNobel
Synthesizing life
2001 StandoutNatureNobel
Identification of Neural Circuits by Imaging Coherent Electrical Activity with FRET-Based Dyes
1999 StandoutNobel
Computational design of receptor and sensor proteins with novel functions
2003 Nature
Imaging exocytosis and endocytosis
1996
DNA-PKcs has KU-dependent function in rRNA processing and haematopoiesis
2020 StandoutNatureNobel
Deep tissue two-photon microscopy
2005 Standout
Modeling biological systems using Dynetica—a simulator of dynamic networks
2003
Controlling Cell Behavior Electrically: Current Views and Future Potential
2005 Standout
A Genetically Encoded Optical Probe of Membrane Voltage
1997
Cell-signalling dynamics in time and space
2006
Lysosome-targeting chimaeras for degradation of extracellular proteins
2020 StandoutNatureNobel
Computational design of ligand-binding proteins with high affinity and selectivity
2013 StandoutNatureNobel
Visualizing secretion and synaptic transmission with pH-sensitive green fluorescent proteins
1998 StandoutNatureNobel
Fluorescent Probes of Cell Signaling
1989 StandoutNobel
Organoid single-cell genomic atlas uncovers human-specific features of brain development
2019 StandoutNatureNobel
Intramolecular donor-acceptor systems. 9. Photophysics of (phenylamino)naphthalenesulfonates: a paradigm for excited-state intramolecular charge transfer
1982
Detection of glutamate release from neurons by genetically encoded surface-displayed FRET nanosensors
2005
Photophysical Properties of Fluorescence Probes. 2. A Model of Multiple Fluorescence for Stilbazolium Dyes Studied by Global Analysis and Quantum Chemical Calculations
1997
Clues from cell metabolism
2010 StandoutNatureNobel
p-Nitrostilbene-tert-Butyl-Nitrone: a Novel Fluorescent Spin Trap for the Detection of ROS with Subcellular Resolution
2009
Structural Changes Accompanying Intramolecular Electron Transfer: Focus on Twisted Intramolecular Charge-Transfer States and Structures
2003 Standout
Upconversion Nanoparticles: Design, Nanochemistry, and Applications in Theranostics
2014 Standout
Activation of TRPV1 channels inhibits mechanosensitive Piezo channel activity by depleting membrane phosphoinositides
2015
Computation-Guided Backbone Grafting of a Discontinuous Motif onto a Protein Scaffold
2011 StandoutScienceNobel
Signaling Recognition Events with Fluorescent Sensors and Switches
1997 Standout
Improved fluorescent probes for the measurement of rapid changes in membrane potential
1982
TIMING OF SYNAPTIC TRANSMISSION
1999
Phase transitions of multivalent proteins can promote clustering of membrane receptors
2014
Genetically Encoded Fluorescent Biosensors Illuminate the Spatiotemporal Regulation of Signaling Networks
2018
Waves and stimulus-modulated dynamics in an oscillating olfactory network.
1994
Interparticle Coupling Effect on the Surface Plasmon Resonance of Gold Nanoparticles: From Theory to Applications
2007 Standout
Cation binding and photophysical properties of a monoaza-15-crown-5-ether linked cyanine dye
1994
1,1-Dicyano-2-[6-(dimethylamino)naphthalen-2-yl]propene (DDNP): A Solvent Polarity and Viscosity Sensitive Fluorophore for Fluorescence Microscopy
1996
Calcium gradients in single smooth muscle cells revealed by the digital imaging microscope using Fura-2
1985 StandoutNatureNobel
Development and Use of Fluorescent Protein Markers in Living Cells
2003 Science
Second harmonic generating (SHG) nanoprobes for in vivo imaging
2010
Systems analysis of PKA-mediated phosphorylation gradients in live cardiac myocytes
2006 StandoutNobel
Fluorescence Lifetime Measurements and Biological Imaging
2010 Standout
Ag@C Core/Shell Structured Nanoparticles: Controlled Synthesis, Characterization, and Assembly
2005
Assemblages: Functional units formed by cellular phase separation
2014
Photophysical properties of fluorescence probes I: dialkylamino stilbazolium dyes
1996
Proton- and calcium-induced fusion and destabilization of liposomes
1985
Resonance energy transfer microscopy: observations of membrane-bound fluorescent probes in model membranes and in living cells.
1986
Optical Methods in Cell Physiology
1997
Design of a Novel Globular Protein Fold with Atomic-Level Accuracy
2003 StandoutScienceNobel
Time-Resolved Fluorescence of a Hemicyanine Dye: Dynamics of Rotamerism and Resolvation
1996
Chain-length dependence of the quadratic hyperpolarizability of push-pull polyenes and carotenoids. Effect of end groups and conjugation path
1994
Progress in Modeling of Protein Structures and Interactions
2005 StandoutScienceNobel
Construction and optimization of a family of genetically encoded metabolite sensors by semirational protein engineering
2005
Optical measurement of synaptic glutamate spillover and reuptake by linker optimized glutamate-sensitive fluorescent reporters
2008 StandoutNobel
Long-Lived Two-Photon Excited Luminescence of Water-Soluble Europium Complex: Applications in Biological Imaging Using Two-Photon Scanning Microscopy
2008
Use of resonance energy transfer to monitor membrane fusion
1981
Fluorescent Dyes as Probes of Voltage Transients in Neuron Membranes Progress Report
1991
Membrane Fusion: Grappling with SNARE and SM Proteins
2009 StandoutScienceNobel
Saturation of Cubic Optical Nonlinearity in Long-Chain Polyene Oligomers
1994 StandoutScienceNobel
Core/Shell Nanoparticles: Classes, Properties, Synthesis Mechanisms, Characterization, and Applications
2011 Standout
De Novo Computational Design of Retro-Aldol Enzymes
2008 StandoutScienceNobel
The Fluorescent Toolbox for Assessing Protein Location and Function
2006 StandoutScienceNobel
Spatiotemporal Patterns of Activity in an Intact Mammalian Network with Single-Cell Resolution: Optical Studies of Nicotinic Activity in an Enteric Plexus
1999
Experimental Models of Primitive Cellular Compartments: Encapsulation, Growth, and Division
2003 StandoutScienceNobel
Seeing the Machinery of Live Cells
1998 StandoutScienceNobel
Orientation and directed migration of cultured corneal epithelial cells in small electric fields are serum dependent
1996
Liquid phase condensation in cell physiology and disease
2017 StandoutScience
Human in vitro models for understanding mechanisms of autism spectrum disorder
2020
SynCAM, a Synaptic Adhesion Molecule That Drives Synapse Assembly
2002 StandoutScienceNobel
Structural basis for gating charge movement in the voltage sensor of a sodium channel
2011 StandoutNobel
Works of Leslie M. Loew being referenced
Stoichiometry of Nck-dependent actin polymerization in living cells
2012
Second-harmonic imaging microscopy for visualizing biomolecular arrays in cells, tissues and organisms
2003
Second-harmonic imaging microscopy of living cells
2001
The Virtual Cell
2002
A general computational framework for modeling cellular structure and function
1997
Pleomorphic Ensembles: Formation of Large Clusters Composed of Weakly Interacting Multivalent Molecules
2013
Chapter 7 Fluorescent Indicators of Membrane Potential: Microspectrofluorometry and Imaging
1989 StandoutNobel
Dual-wavelength ratiometric fluorescence measurement of the membrane dipole potential
1994
Molecular machines or pleiomorphic ensembles: signaling complexes revisited
2009
Novel naphthylstyryl-pyridinium potentiometric dyes offer advantages for neural network analysis
2004
Spatial Modeling of Cell Signaling Networks
2012
Physiological modeling with virtual cell framework
2000
Dual-wavelength ratiometric fluorescence measurements of membrane potential
1989
Quantitative cell biology with the Virtual Cell☆
2003
Sensitivity of Second Harmonic Generation from Styryl Dyes to Transmembrane Potential
2004
Simultaneous imaging of cell and mitochondrial membrane potentials
1989
Characterization and Application of a New Optical Probe for Membrane Lipid Domains
2006
Imaging in five dimensions: time-dependent membrane potentials in individual mitochondria
1993
The Virtual Cell: a software environment for computational cell biology
2001
Direct measurement of the voltage sensitivity of second-harmonic generation from a membrane dye in patch-clamped cells
2003
A naphthyl analog of the aminostyryl pyridinium class of potentiometric membrane dyes shows consistent sensitivity in a variety of tissue, cell, and model membrane preparations
1992
High-Resolution Nonlinear Optical Imaging of Live Cells by Second Harmonic Generation
1999
Synthesis, spectra, delivery and potentiometric responses of new styryl dyes with extended spectral ranges
2005
Localized membrane depolarizations and localized calcium influx during electric field-guided neurite growth
1992
Determination of Time-Dependent Inositol-1,4,5-Trisphosphate Concentrations during Calcium Release in a Smooth Muscle Cell
1999
Construction of a fluorescent biosensor family
2002
Cholesterol-Enriched Lipid Domains Can Be Visualized by di-4-ANEPPDHQ with Linear and Nonlinear Optics
2005
A Fluorometric Approach to Local Electric Field Measurements in a Voltage-Gated Ion Channel
2003
Probing membrane potential with nonlinear optics
1993
Hyperexcitable Phenotypes in Induced Pluripotent Stem Cell–Derived Neurons From Patients With 15q11-q13 Duplication Syndrome, a Genetic Form of Autism
2021
The Virtual Cell
1998
Design and characterization of electrochromic membrane probes
1982
Spectra, membrane binding, and potentiometric responses of new charge shift probes
1985
Evidence for a charge-shift electrochromic mechanism in a probe of membrane potential
1979 Nature
Analysis of nonlinear dynamics on arbitrary geometries with the Virtual Cell
2001
Physiological cytosolic Ca2+ transients evoke concurrent mitochondrial depolarizations.
1994
Systems Analysis of Ran Transport
2002 Science
Kinetic analysis of receptor-activated phosphoinositide turnover
2003
Electric field-directed fibroblast locomotion involves cell surface molecular reorganization and is calcium independent.
1994
Phospholipid vesicle fusion monitored by fluorescence energy transfer
1979
Potentiometric dyes: Imaging electrical activity of cell membranes
1996
Charge-shift probes of membrane potential: a probable electrochromic mechanism for p-aminostyrylpyridinium probes on a hemispherical lipid bilayer
1981
Second Harmonic Generation Properties of Fluorescent Polymer-Encapsulated Gold Nanoparticles
2000
Charge-shift probes of membrane potential. Synthesis
1984
Application of Forster resonance energy transfer to interactions between cell or lipid vesicle surfaces
1979
Charge-shift probes of membrane potential. Characterization of aminostyrylpyridinium dyes on the squid giant axon
1985
Optical imaging of cell membrane potential changes induced by applied electric fields
1986
An unexpected blue shift caused by differential solvation of a chromophore oriented in a lipid bilayer
1979
Charge shift optical probes of membrane potential. Theory
1978
Nonlinear optical measurement of membrane potential around single molecules at selected cellular sites
1999