Citation Impact
Citing Papers
Notch signaling controls liver development by regulating biliary differentiation
2009
microRNA-92a Promotes Lymph Node Metastasis of Human Esophageal Squamous Cell Carcinoma via E-Cadherin
2010
Genetics of mouse growth
1998
The miR-17/92 cluster: a comprehensive update on its genomics, genetics, functions and increasingly important and numerous roles in health and disease
2013
Basal cell carcinomas: attack of the hedgehog
2008 Standout
Structure of the PAPP-ABP5 complex reveals mechanism of substrate recognition
2022 StandoutNobel
HuR-dependent loading of miRNA RISC to the mRNA encoding the Ras-related small GTPase RhoB controls its translation during UV-induced apoptosis
2011
Ischemia and reperfusion—from mechanism to translation
2011 Standout
Hepatocellular carcinoma
2003 Standout
Unraveling signalling cascades for the Snail family of transcription factors
2004
Dysregulation of growth factor signaling in human hepatocellular carcinoma
2006
MYC on the Path to Cancer
2012 Standout
Molecular pathogenesis of human hepatocellular carcinoma
2002
Recent advances in BMP receptor signaling
2009
Epithelial-Mesenchymal Transitions in Development and Disease
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mTOR Interacts with Raptor to Form a Nutrient-Sensitive Complex that Signals to the Cell Growth Machinery
2002 Standout
EMT and Dissemination Precede Pancreatic Tumor Formation
2012 Standout
MicroRNA Expression Profile in Lieber‐DeCarli Diet‐Induced Alcoholic and Methionine Choline Deficient Diet‐Induced Nonalcoholic Steatohepatitis Models in Mice
2009
IGF-Binding Proteins: Why Do They Exist and Why Are There So Many?
2018
Expression of paramyxovirus V proteins promotes replication and spread of hepatitis C virus in cultures of primary human fetal liver cells
2010 StandoutNobel
WNT signalling pathways as therapeutic targets in cancer
2012 Standout
Experimental models of hepatocellular carcinoma
2008
New insight in the pathobiology of hepatitis B virus infection
2012
Mouse brains deficient in H‐ferritin have normal iron concentration but a protein profile of iron deficiency and increased evidence of oxidative stress
2002
Balancing Acts
2004 Standout
A Regulatory Cascade of the Nuclear Receptors FXR, SHP-1, and LRH-1 Represses Bile Acid Biosynthesis
2000 Standout
Molecular Mechanism of Liver Development and Regeneration
2007
Hepatocellular carcinoma
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Cancer stem cells revisited
2017 Standout
Suppression of type I collagen production by microRNA-29b in cultured human stellate cells
2009
The multilayered complexity of ceRNA crosstalk and competition
2014 StandoutNature
Global mapping of miRNA-target interactions in cattle (Bos taurus)
2017 StandoutNobel
Mapping and analysis of chromatin state dynamics in nine human cell types
2011 StandoutNature
Major components of the insulin-like growth factor axis are expressed early in chicken embryogenesis, with IGF binding protein ( IGFBP ) -5 expression subject to regulation by Sonic Hedgehog
2003
Insulin-like growth factor binding proteins and their role in controlling IGF actions
1997
MicroRNA control of signal transduction
2010
A novel mouse model of hepatocarcinogenesis triggered by AID causing deleterious p53 mutations
2008 StandoutNobel
Insulin and insulin-like growth factor signalling in neoplasia
2008 Standout
WNT signaling in bone homeostasis and disease: from human mutations to treatments
2013 Standout
Chemical remodelling of cell surfaces in living animals
2004 StandoutNatureNobel
MicroRNA-21 Regulates Expression of the PTEN Tumor Suppressor Gene in Human Hepatocellular Cancer
2007 Standout
Snail, Zeb and bHLH factors in tumour progression: an alliance against the epithelial phenotype?
2007 Standout
Insulin-like Growth Factor Binding Proteins
1993
Expression of activation-induced cytidine deaminase in human hepatocytes via NF-κB signaling
2007 StandoutNobel
MicroRNA therapeutics: towards a new era for the management of cancer and other diseases
2017 Standout
EMT: 2016
2016 Standout
Mechanisms of fibrosis: therapeutic translation for fibrotic disease
2012 Standout
miR‐21: a small multi‐faceted RNA
2008
Long-Term Expansion of Functional Mouse and Human Hepatocytes as 3D Organoids
2018 StandoutNobel
MicroRNAs and Cancer: Short RNAs Go a Long Way
2009
Liver development update: new embryo models, cell lineage control, and morphogenesis
2004
Circulating MicroRNAs, miR-21, miR-122, and miR-223, in patients with hepatocellular carcinoma or chronic hepatitis
2010
Insulin-like growth factor I and II and insulin-like growth factor binding protein-2 RNAs are expressed in adjacent tissues within rat embryonic and fetal limbs
1992
PAPP-A and the IGF system
2016
Coinhibitory Receptor Expression and Immune Checkpoint Blockade: Maintaining a Balance in CD8+ T Cell Responses to Chronic Viral Infections and Cancer
2017 StandoutNobel
Lineage tracing demonstrates no evidence of cholangiocyte epithelial-to-mesenchymal transition in murine models of hepatic fibrosis
2011
The biogenesis, biology and characterization of circular RNAs
2019 Standout
Alcoholic Liver Disease: Pathogenesis and New Therapeutic Targets
2011 Standout
Stem/Progenitor Cells in Liver Development, Homeostasis, Regeneration, and Reprogramming
2014
A coding-independent function of gene and pseudogene mRNAs regulates tumour biology
2010 StandoutNature
Hepatocellular carcinoma pathogenesis: from genes to environment
2006 Standout
Emerging roles of microRNAs in the control of embryonic stem cells and the generation of induced pluripotent stem cells
2010
Organ‐specific profiles of genetic changes in cancers caused by activation‐induced cytidine deaminase expression
2008 StandoutNobel
Genomic imprinting: parental influence on the genome
2001 Standout
Insulin-like growth factors (IGFs), IGF receptors, and IGF-binding proteins: Roles in skeletal muscle growth and differentiation
2010
TheCaenorhabditis elegansOrphan Nuclear Hormone Receptor Genenhr-2Functions in Early Embryonic Development
1997 StandoutNobel
Regulatory networks defining EMT during cancer initiation and progression
2013 Standout
NF-κB, inflammation, immunity and cancer: coming of age
2018 Standout
MicroRNA control of epithelial–mesenchymal transition and metastasis
2012
Cooperative and individualistic functions of the microRNAs in the miR-23a~27a~24-2 cluster and its implication in human diseases
2010
New perspectives on the diversification of theRNA interference system: insights from comparative genomics and smallRNA sequencing
2013
Partial Deletion of Pten in the Hypothalamus Leads to Growth Defects that Cannot be Rescued by Exogenous Growth Hormone
2008 StandoutNobel
Cellular Actions of the Insulin-Like Growth Factor Binding Proteins
2002
Molecular Profiling of Human Hepatocellular Carcinoma Defines Mutually Exclusive Interferon Regulation and Insulin-Like Growth Factor II Overexpression
2004
Mice carrying null mutations of the genes encoding insulin-like growth factor I (Igf-1) and type 1 IGF receptor (Igf1r)
1993 Standout
40 YEARS OF IGF1: IGF-binding proteins
2017
MicroRNA ‐23b‐3p regulates human keratinocyte differentiation through repression of TGIF 1 and activation of the TGF ‐ß–SMAD 2 signalling pathway
2016
Modeling host interactions with hepatitis B virus using primary and induced pluripotent stem cell-derived hepatocellular systems
2014 StandoutNobel
In situ expansion of engineered human liver tissue in a mouse model of chronic liver disease
2017 StandoutNobel
A bacterial Argonaute with noncanonical guide RNA specificity
2016 StandoutNobel
Insulin Resistance and the Polycystic Ovary Syndrome: Mechanism and Implications for Pathogenesis*
1997 Standout
Bipotential Adult Liver Progenitors Are Derived from Chronically Injured Mature Hepatocytes
2014
Genetic identification of HSD-1, a conserved steroidogenic enzyme that directs larval development inCaenorhabditis elegans
2008 StandoutNobel
Phenotype reversion in fetal human liver epithelial cells identifies the role of an intermediate meso-endodermal stage before hepatic maturation
2008
miR-24 inhibits apoptosis and represses Bim in mouse cardiomyocytes
2011
Hepatocellular Carcinoma: Epidemiology and Molecular Carcinogenesis
2007 Standout
Epigenetic regulation in pluripotent stem cells: a key to breaking the epigenetic barrier
2012 StandoutNobel
Mechanisms of Diabetic Complications
2013 Standout
Dauer larva quiescence alters the circuitry of microRNA pathways regulating cell fate progression inC. elegans
2012 StandoutNobel
Insulin-like Growth Factor II Signaling in Neoplastic Proliferation Is Blocked by Transgenic Expression of the Metalloproteinase Inhibitor Timp-1
1999
Overview of Steroidogenic Enzymes in the Pathway from Cholesterol to Active Steroid Hormones
2004
Cellular Homeostasis and Repair in the Mammalian Liver
2015
MicroRNAs, new effectors and regulators of NF‐κB
2012 Nobel
The Myc–miR-17∼92 Axis Blunts TGFβ Signaling and Production of Multiple TGFβ-Dependent Antiangiogenic Factors
2010
Characterization of the mouse FTZ-F1 gene, which encodes a key regulator of steroid hydroxylase gene expression.
1993
Regulation of Wound Healing by Growth Factors and Cytokines
2003 Standout
Works of Leslie E. Rogler being referenced
Overexpression of miR-21 Promotes an In vitro Metastatic Phenotype by Targeting the Tumor Suppressor RHOB
2010
cDNA microarray analysis of HBV transgenic mouse liver identifies genes in lipid biosynthetic and growth control pathways affected by HBV
2005
Small RNAs derived from lncRNA RNase MRP have gene-silencing activity relevant to human cartilage–hair hypoplasia
2013
New cell surface markers for murine fetal hepatic stem cells identified through high density complementary DNA microarrays†
2007
Elevated Expression of the miR-17–92 Polycistron and miR-21 in Hepadnavirus-Associated Hepatocellular Carcinoma Contributes to the Malignant Phenotype
2008
Transcriptional profiling implicates TGFβ/BMP and Notch signaling pathways in ductular differentiation of fetal murine hepatoblasts
2006
Reactivation of the maternally imprinted IGF2 allele in TGFα induced hepatocellular carcinomas in mice
1998
Identification of hepatocytic and bile ductular cell lineages and candidate stem cells in bipolar ductular reactions in cirrhotic human liver
2007
Genomic expression analysis implicates Wnt signaling pathway and extracellular matrix alterations in hepatic specification and differentiation of murine hepatic stem cells
2001
Expression of IGF-II, the IGF-II/Mannose-6-Phosphate Receptor and IGFBP-2 During Rat Embryogenesis
1991
MicroRNA‐23b cluster microRNAs regulate transforming growth factor‐beta/bone morphogenetic protein signaling and liver stem cell differentiation by targeting Smads†
2009
Expression of the P450 side-chain cleavage and adrenodoxin genes begins during early stages of adrenal cortex development.
1993
Regulation of hepatitis B virus expression in progenitor and differentiated cell types: evidence for negative transcriptional control in nonpermissive cells.
1999
Selective Alterations in Organ Sizes in Mice with a Targeted Disruption of the Insulin-Like Growth Factor Binding Protein-2 Gene
2000
Targeted disruption of IGFBP-2 gene.
1993