Citation Impact
Citing Papers
High-throughput characterization of protein–protein interactions by reprogramming yeast mating
2017 StandoutNobel
A noninflammatory mRNA vaccine for treatment of experimental autoimmune encephalomyelitis
2021 StandoutScienceNobel
Suppression of bone resorption by madindoline A, a novel nonpeptide antagonist to gp130
2002 StandoutNobel
The microbiota regulates type 2 immunity through RORγt + T cells
2015 StandoutScienceNobel
Regulation of cytokines, cytokine inhibitors, and acute-phase proteins following anti-TNF-alpha therapy in rheumatoid arthritis.
1999
Delayed onset and reduced severity of collagen-induced arthritis in interleukin-6-deficient mice
1999
Target-conditioned diffusion generates potent TNFR superfamily antagonists and agonists
2024 StandoutScienceNobel
ANKTM1, a TRP-like Channel Expressed in Nociceptive Neurons, Is Activated by Cold Temperatures
2003 StandoutNobel
Cytokines and direct cell contact in synovitis: relevance to therapeutic intervention.
1999
TGFβ in the Context of an Inflammatory Cytokine Milieu Supports De Novo Differentiation of IL-17-Producing T Cells
2006 Standout
Re-establishing immunological self-tolerance in autoimmune disease
2012 StandoutNobel
Dissecting autoimmune diabetes through genetic manipulation of non-obese diabetic mice
2003
Inflammation and cancer
2002 StandoutNature
Susceptibility to Collagen-Induced Arthritis: Cytokine-Mediated Regulation
2001
Infliximab for the Treatment of Fistulas in Patients with Crohn's Disease
1999 Standout
Inflammation and metabolic disorders
2006 StandoutNature
The expression of tumor necrosis factor in human adipose tissue. Regulation by obesity, weight loss, and relationship to lipoprotein lipase.
1995
CD22 blockade restores homeostatic microglial phagocytosis in ageing brains
2019 StandoutNatureNobel
Functional Consequences of the SHP-1 Defect in Motheaten Viable Mice: Role of NF-κB
1998
Astrocytes and Microglia as Major Players of Myelin Production in Normal and Pathological Conditions
2020
TNF defined as a therapeutic target for rheumatoid arthritis and other autoimmune diseases
2003
CD4+ T-cell subsets in autoimmunity
1997
Regulatory T Cells
2000 StandoutNobel
Regulatory T Cells and Immune Tolerance
2008 StandoutNobel
Local Expression of TNFα in Neonatal NOD Mice Promotes Diabetes by Enhancing Presentation of Islet Antigens
1998
A Short-Term Study of Chimeric Monoclonal Antibody cA2 to Tumor Necrosis Factor α for Crohn's Disease
1997 Standout
Tumor Necrosis Factor-α Blockade: A Novel Therapy for Rheumatic Disease
2002
Developmental regulation of MHC class II transport in mouse dendritic cells
1997 StandoutNatureNobel
Could endogenous self-peptides presented by dendritic cells initiate rheumatoid arthritis?
1996
Functional characterization of a soluble gp130 isoform and its therapeutic capacity in an experimental model of inflammatory arthritis
2006
Blood–brain barrier breakdown in Alzheimer disease and other neurodegenerative disorders
2018 Standout
IL-6 as a keystone cytokine in health and disease
2015 Standout
Skeletal remodeling in health and disease
2007 Standout
Cytokine Pathways and Joint Inflammation in Rheumatoid Arthritis
2001 Standout
Understanding pathogenesis and therapy of multiple sclerosis via animal models: 70 years of merits and culprits in experimental autoimmune encephalomyelitis research
2006
Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells
2006 StandoutNature
Altered thymic T-cell selection due to a mutation of the ZAP-70 gene causes autoimmune arthritis in mice
2003 StandoutNatureNobel
A protein kinase involved in the regulation of inflammatory cytokine biosynthesis
1994 StandoutNature
IL-6 induces an anti-inflammatory response in the absence of SOCS3 in macrophages
2003
The KRN mouse model of inflammatory arthritis
2003
Toll-like receptors: balancing host resistance with immune tolerance
2003
Hypothalamic programming of systemic ageing involving IKK-β, NF-κB and GnRH
2013 Nature
Blockage of interleukin-6 receptor ameliorates joint disease in murine collagen-induced arthritis
1998
Role of TNF–TNF Receptor 2 Signal in Regulatory T Cells and Its Therapeutic Implications
2018
Organ-Specific Disease Provoked by Systemic Autoimmunity
1996
Affinity maturation of Fab antibody fragments by fluorescent‐activated cell sorting of yeast‐displayed libraries
2003
Through thick and thin: Wasting, obesity, and TNFα
1993
Identification of a cold receptor reveals a general role for TRP channels in thermosensation
2002 StandoutNatureNobel
Therapeutic strategies for the clinical blockade of IL-6/gp130 signaling
2011
Control of TH17/Treg Balance by Hypoxia-Inducible Factor 1
2011 StandoutNobel
Regulation of autoimmunity by proinflammatory cytokines
1998
Distinct contribution of IL-6, TNF-α, IL-1, and IL-10 to T cell–mediated spontaneous autoimmune arthritis in mice
2004 StandoutNobel
Cytokines in the pathogenesis of rheumatoid arthritis
2007 Standout
The Hallmarks of Aging
2013 Standout
Synovial mast cells: role in acute and chronic arthritis
2007
How Cytokine Networks Fuel Inflammation: Toward a cytokine-based disease taxonomy
2013
Mast cells in the pathogenesis of rheumatic diseases and as potential targets for anti‐rheumatic therapy
2007
Anticytokine treatment of established type II collagen–induced arthritis in DBA/1 mice: A comparative study using anti‐TNFα, anti–IL‐1α/β, and IL‐1Ra
1996
Treatment of rheumatoid arthritis with chimeric monoclonal antibodies to tumor necrosis factor α
1993
Selective Targeting of TNF Receptors as a Novel Therapeutic Approach
2020
Rheumatoid Arthritis
1996
JNK1 is not essential for TNF-mediated joint disease
2004
The Tumor Necrosis Factor Ligand and Receptor Families
1996 StandoutNobel
Establishment of NOD-Pdcd1-/-mice as an efficient animal model of type I diabetes
2005 StandoutNobel
RTP4 inhibits IFN-I response and enhances experimental cerebral malaria and neuropathology
2020 StandoutNobel
Extinction of the tumor necrosis factor locus, and of genes encoding the lipopolysaccharide signaling pathway.
1993 StandoutNobel
Dendritic cells with TGF-β1 differentiate naïve CD4+CD25−T cells into islet-protective Foxp3+regulatory T cells
2007 StandoutNobel
Beneficial effects of tumour necrosis factor-alpha (TNF-α) blockade in rheumatoid arthritis (RA)
1995
Neuropeptide Y in the Peripheral Adrenergic and Enteric Nervous Systems
1986
IL-6 Trans-Signaling Modulates TLR4-Dependent Inflammatory Responses via STAT3
2010
Cloning and functional expression of cDNAs encoding human and rat pancreatic polypeptide receptors.
1996 StandoutNobel
ROLE OF CYTOKINES IN RHEUMATOID ARTHRITIS
1996 Standout
Anticytokine treatment of established type II collagen-induced arthritis in DBA/1 mice: A comparative study using anti-TNFα, anti-IL-1α/β and IL-1Ra
2008
Response Properties of Mechanoreceptors and Nociceptors in Mouse Glabrous Skin: An In Vivo Study
2001
IL‐6 controls susceptibility to helminth infection by impeding Th2 responsiveness and altering the Treg phenotype in vivo
2013
Recombinant Human IFN-α Inhibits Cerebral Malaria and Reduces Parasite Burden in Mice
2007
T Cell Studies in a Peptide-Induced Model of Systemic Lupus Erythematosus
2001 StandoutNobel
A role for fungal β-glucans and their receptor Dectin-1 in the induction of autoimmune arthritis in genetically susceptible mice
2005 StandoutNobel
Dynamics of proinflammatory cytokine expression in the joints of mice with collagen-induced arthritis (CIA)
1997
Mast cells contribute to initiation of autoantibody-mediated arthritis via IL-1
2007
Single-nanometer iron oxide nanoparticles as tissue-permeable MRI contrast agents
2021 StandoutNobel
Increase in TNF-α and inducible nitric oxide synthase-expressing dendritic cells in psoriasis and reduction with efalizumab (anti-CD11a)
2005 StandoutNobel
Inflammation and autoimmunity caused by a SHP1 mutation depend on IL-1, MyD88, and a microbial trigger
2008 StandoutNobel
The soluble interleukin 6 receptor: mechanisms of production and implications in disease
2001
Regulation of Cytokines, Cytokine Inhibitors, and Acute-Phase Proteins Following Anti-TNF-α Therapy in Rheumatoid Arthritis
1999
Emerging Challenges in Regulatory T Cell Function and Biology
2007 StandoutScienceNobel
PD-1 deficiency reveals various tissue-specific autoimmunity by H-2band dose-dependent requirement of H-2g7for diabetes in NOD mice
2008 StandoutNobel
Superantigen overcomes resistance of IL‐6‐deficient mice towards MOG‐induced EAE by a TNFR1 controlled pathway
2001
Detection of T cell responses to a ubiquitous cellular protein in autoimmune disease
2014 StandoutScienceNobel
Chimeric tumor necrosis factor receptors with constitutive signaling activity.
1995 StandoutNobel
IL-6 Increases Primed Cell Expansion and Survival
2005
Epigenetic conversion of conventional T cells into regulatory T cells by CD28 signal deprivation
2020 StandoutNobel
Pinpointing when T cell costimulatory receptor CTLA-4 must be engaged to dampen diabetogenic T cells
2000 StandoutNobel
Neurodegenerative and Neuroprotective Effects of Tumor Necrosis Factor (TNF) in Retinal Ischemia: Opposite Roles of TNF Receptor 1 and TNF Receptor 2
2002
Immunotherapy: Bewitched, Bothered, and Bewildered No More
2004 StandoutScienceNobel
Anti-tumor necrosis factor ameliorates joint disease in murine collagen-induced arthritis.
1992 Standout
Distinct contribution of IL-6, TNF-α, IL-1, and IL-10 to T cell–mediated spontaneous autoimmune arthritis in mice
2004 StandoutNobel
A Point Mutation of Tyr-759 in Interleukin 6 Family Cytokine Receptor Subunit gp130 Causes Autoimmune Arthritis
2002
Although IL-6 Trans-Signaling Is Sufficient To Drive Local Immune Responses, Classical IL-6 Signaling Is Obligate for the Induction of T Cell-Mediated Autoimmunity
2010
Adjuvant-Enhanced Antibody Responses in the Absence of Toll-Like Receptor Signaling
2006 StandoutScienceNobel
Critical Roles for Interleukin 1 and Tumor Necrosis Factor α in Antibody-induced Arthritis
2002
JNK1 controls mast cell degranulation and IL-1β production in inflammatory arthritis
2010 StandoutNobel
Chronic exposure to tumor necrosis factor (TNF) in vitro impairs the activation of T cells through the T cell receptor/CD3 complex; reversal in vivo by anti-TNF antibodies in patients with rheumatoid arthritis.
1994
Structure and Function of DNA Photolyase and Cryptochrome Blue-Light Photoreceptors
2003 StandoutNobel
Tumor necrosis factor-α regulation of CD4+C25+T cell levels in NOD mice
2002
Works of Lesley Probert being referenced
Transgenic Models of Tnf Induced Demyelination
1999
Therapeutic inhibition of soluble brain TNF promotes remyelination by increasing myelin phagocytosis by microglia
2017
TNFR1 signalling is critical for the development of demyelination and the limitation of T-cell responses during immune-mediated CNS disease
2000
TNF accelerates the onset but does not alter the incidence and severity of myelin basic protein-induced experimental autoimmune encephalomyelitis
1999
TNF-α transgenic and knockout models of CNS inflammation and degeneration
1997
The type I interleukin‐1 receptor acts in series with tumor necrosis factor (TNF) to induce arthritis in TNF‐transgenic mice
1995
The Mouse/Human Chimeric Monoclonal Antibody cA2 Neutralizes TNF In Vitro and Protects Transgenic Mice from Cachexia and TNF Lethality In Vivo
1995
Wasting, ischemia, and lymphoid abnormalities in mice expressing T cell-targeted human tumor necrosis factor transgenes.
1993
Transgenic and knockout analyses of the role of TNF in immune regulation and disease pathogenesis.
1997
Calcitonin-like cells in the pharynx of the ascidian Styela clava
1979
Dissection of the pathologies induced by transmembrane and wild-type tumor necrosis factor in transgenic mice
1996
Spontaneous inflammatory demyelinating disease in transgenic mice showing central nervous system-specific expression of tumor necrosis factor alpha.
1995
Chronic Tumor Necrosis Factor Alters T Cell Responses by Attenuating T Cell Receptor Signaling
1997
Anaemia and resistance to malaria in transgenic mice expressing human tumour necrosis factor.
1994
Interleukin 6 Is Required for the Development of Collagen-induced Arthritis
1998
Transgenic mice expressing human tumour necrosis factor: a predictive genetic model of arthritis.
1991
Transmembrane tumour necrosis factor is neuroprotective and regulates experimental autoimmune encephalomyelitis via neuronal nuclear factor-κB
2011
TNF receptor I sensitizes neurons to erythropoietin- and VEGF-mediated neuroprotection after ischemic and excitotoxic injury
2008
LEVEL OF NERVE GROWTH FACTOR AND DISTRIBUTION OF MAST CELLS IN THE SYNOVIUM OF TUMOUR NECROSIS FACTOR TRANSGENIC ARTHRITIC MICE
1997 Nobel
Fibrin depletion decreases inflammation and delays the onset of demyelination in a tumor necrosis factor transgenic mouse model for multiple sclerosis
2004
Peptidergic Innervation of the Human Male Genital Tract
1983