Citation Impact
Citing Papers
PARP inhibitors: Synthetic lethality in the clinic
2017 StandoutScience
Kinetics of vascular normalization by VEGFR2 blockade governs brain tumor response to radiation
2004 Standout
A Designed Angiopoietin-1 Variant, Dimeric CMP-Ang1 Activates Tie2 and Stimulates Angiogenesis and Vascular Stabilization in N-glycan Dependent Manner
2015
Targeting Vascular Pericytes in Hypoxic Tumors Increases Lung Metastasis via Angiopoietin-2
2015
Pericytes are required for blood–brain barrier integrity during embryogenesis
2010 StandoutNature
Differential function of Tie2 at cell–cell contacts and cell–substratum contacts regulated by angiopoietin-1
2008
Self-Renewing Osteoprogenitors in Bone Marrow Sinusoids Can Organize a Hematopoietic Microenvironment
2007 Standout
Adult pancreatic β-cells are formed by self-duplication rather than stem-cell differentiation
2004 StandoutNature
Angiopoietin and Tie signaling pathways in vascular development
2001
PARP inhibitor combination therapy
2016
Molecular mechanisms of blood vessel growth
2001
Cell Signaling by Receptor Tyrosine Kinases
2010 Standout
Cancer Metastasis: Building a Framework
2006 Standout
Activation of the Tie2 Receptor by Angiopoietin-1 Enhances Tumor Vessel Maturation and Impairs Squamous Cell Carcinoma Growth
2002
Ranibizumab for Neovascular Age-Related Macular Degeneration
2006 Standout
Epithelial-to-mesenchymal transition is dispensable for metastasis but induces chemoresistance in pancreatic cancer
2015 StandoutNature
Discovery and development of bevacizumab, an anti-VEGF antibody for treating cancer
2004 Standout
New insights into nNOS regulation of vascular homeostasis
2005 StandoutNobel
Influence of tumour micro-environment heterogeneity on therapeutic response
2013 StandoutNature
Alteration of Developmental and Pathological Retinal Angiogenesis in angptl4-deficient Mice
2011
Angiogenesis in cancer and other diseases
2000 StandoutNature
Expression of Vascular Endothelial Growth Factor Receptor 1 in Bone Marrow-derived Mesenchymal Cells Is Dependent on Hypoxia-inducible Factor 1
2006 StandoutNobel
Severe Sepsis and Septic Shock
2013 Standout
Angiogenesis in health and disease
2003 Standout
Deletion of the Carboxyl Terminus of Tie2 Enhances Kinase Activity, Signaling, and Function
2002
Double Antiangiogenic Protein, DAAP, Targeting VEGF-A and Angiopoietins in Tumor Angiogenesis, Metastasis, and Vascular Leakage
2010
Evolving functions of endothelial cells in inflammation
2007
Lymphangiogenesis in development and human disease
2005 StandoutNature
Incorporation of Bevacizumab in the Primary Treatment of Ovarian Cancer
2011 Standout
Oligomerization and Multimerization Are Critical for Angiopoietin-1 to Bind and Phosphorylate Tie2
2005
Regulation of angiogenesis by hypoxia: role of the HIF system
2003 StandoutNobel
Angiogenesis in life, disease and medicine
2005 StandoutNature
High interstitial fluid pressure — an obstacle in cancer therapy
2004 Standout
Angiopoietin-1 reduces cerebral blood vessel leakage and ischemic lesion volume after focal cerebral embolic ischemia in mice
2002
Molecular regulation of vessel maturation
2003 Standout
The Extracellular Matrix of Blood Vessels
2009
Vascular-specific growth factors and blood vessel formation
2000 StandoutNature
Targeting Tie2 for Treatment of Diabetic Retinopathy and Diabetic Macular Edema
2016
Origin and physiological roles of inflammation
2008 StandoutNature
Sox18 induces development of the lymphatic vasculature in mice
2008 StandoutNature
Therapeutic targeting of the angiopoietin–TIE pathway
2017
Genetic dissection of tumor angiogenesis: are PlGF and VEGFR-1 novel anti-cancer targets?
2003
Basic and Therapeutic Aspects of Angiogenesis
2011 Standout
Induction of angiogenesis in a mouse model using engineered transcription factors
2002
Mechanisms of angiogenesis and arteriogenesis
2000 Standout
Adenovirus-mediated HIF-1α gene transfer promotes repair of mouse airway allograft microvasculature and attenuates chronic rejection
2011 StandoutNobel
Targeting the ANGPT–TIE2 pathway in malignancy
2010
Enhanced Benefit in Diabetic Macular Edema from AKB-9778 Tie2 Activation Combined with Vascular Endothelial Growth Factor Suppression
2016
Oxygen Sensing, Homeostasis, and Disease
2011 StandoutNobel
Enhancing cancer immunotherapy using antiangiogenics: opportunities and challenges
2018
Vascular Growth in Ischemic Limbs: A Review of Mechanisms and Possible Therapeutic Stimulation
2008
Recombinant angiopoietin-1 restores higher-order architecture of growing blood vessels in mice in the absence of mural cells
2002
SSeCKS regulates angiogenesis and tight junction formation in blood-brain barrier
2003
Molecular mechanisms and clinical applications of angiogenesis
2011 StandoutNature
VEGF in Signaling and Disease: Beyond Discovery and Development
2019 Standout
Control of vascular morphogenesis and homeostasis through the angiopoietin–Tie system
2009
Angiogenesis as a therapeutic target
2005 StandoutNature
Tumor Angiogenesis
2008 Standout
Targeting key angiogenic pathways with a bispecific Cross MA b optimized for neovascular eye diseases
2016
COMP-Ang1: A designed angiopoietin-1 variant with nonleaky angiogenic activity
2004
Atezolizumab for First-Line Treatment of Metastatic Nonsquamous NSCLC
2018 Standout
Phase II Trial of Bevacizumab in Persistent or Recurrent Epithelial Ovarian Cancer or Primary Peritoneal Cancer: A Gynecologic Oncology Group Study
2007
Angiogenesis
2005
The well-tempered vessel
2001
Vascular Endothelial Growth Factor and Angiopoietin-1 Stimulate Postnatal Hematopoiesis by Recruitment of Vasculogenic and Hematopoietic Stem Cells
2001
VEGF-Induced BBB Permeability is Associated with an MMP-9 Activity Increase in Cerebral ischemia: Both Effects Decreased by ANG-1
2005
Angiopoietin-1 inhibits vascular permeability, angiogenesis, and growth of hepatic colon cancer tumors.
2003
Vascular Endothelial Growth Factor: Basic Science and Clinical Progress
2004 Standout
Normalization of the Vasculature for Treatment of Cancer and Other Diseases
2011
Photodegradable Hydrogels for Dynamic Tuning of Physical and Chemical Properties
2009 StandoutScience
Polymeric system for dual growth factor delivery
2001
Biochemical purification and pharmacological inhibition of a mammalian prolyl hydroxylase acting on hypoxia-inducible factor
2002 StandoutNobel
Broken Barriers: A New Take on Sepsis Pathogenesis
2011
Opposing actions of angiopoietin-2 on Tie2 signaling and FOXO1 activation
2016
Recombinant angiopoietin-1 restores higher-order architecture of growing blood vessels in mice in the absence of mural cells
2002
VEGF gene therapy: stimulating angiogenesis or angioma-genesis?
2000
Tissue Engineering--Current Challenges and Expanding Opportunities
2002 StandoutScience
Regulation of hypoxia-induced angiogenesis: a chaperone escorts VEGF to the dance
2001 StandoutNobel
F‐domain valency determines outcome of signaling through the angiopoietin pathway
2021 StandoutNobel
Angiopoietin1/TIE2 and VEGF/FLK1 Induced by MSC Treatment Amplifies Angiogenesis and Vascular Stabilization after Stroke
2007
Angiopoietin-1/Tie2 receptor signaling in vascular quiescence and angiogenesis.
2010
Endothelial Hypoxia-Inducible Factor-2α Is Required for the Maintenance of Airway Microvasculature
2019 StandoutNobel
Angiopoietin-1 reduces vascular endothelial growth factor-induced brain endothelial permeability via upregulation of ZO-2
1998
Normalization of Tumor Vasculature: An Emerging Concept in Antiangiogenic Therapy
2005 StandoutScience
Peptide blockade of HIFα degradation modulates cellular metabolism and angiogenesis
2002 StandoutNobel
Cell-Demanded Liberation of VEGF 121 From Fibrin Implants Induces Local and Controlled Blood Vessel Growth
2004
Phase II Study of Bevacizumab in Patients With Platinum-Resistant Ovarian Cancer or Peritoneal Serous Cancer
2007
Hypoxic retinal Müller cells promote vascular permeability by HIF-1–dependent up-regulation of angiopoietin-like 4
2013 StandoutNobel
Angiopoietin-1 Guides Directional Angiogenesis Through Integrin α v β 5 Signaling for Recovery of Ischemic Retinopathy
2013
Stabilized HIF‐1α is superior to VEGF for angiogenesis in skeletal muscle via adeno‐associated virus gene transfer
2005
Synergistic effect of HIF-1α gene therapy and HIF-1-activated bone marrow-derived angiogenic cells in a mouse model of limb ischemia
2009 StandoutNobel
Adenoviral transfer of HIF-1α enhances vascular responses to critical limb ischemia in diabetic mice
2009 StandoutNobel
Signaling and Functions of Angiopoietin-1 in Vascular Protection
2006
Top-down design of protein architectures with reinforcement learning
2023 StandoutScienceNobel
Role ofVHLGene Mutation in Human Cancer
2004 StandoutNobel
Age-Related Changes in Vascular Endothelial Growth Factor Dependency and Angiopoietin-1-Induced Plasticity of Adult Blood Vessels
2004
Designed angiopoietin-1 variant, COMP-Ang1, protects against radiation-induced endothelial cell apoptosis
2004
Structural basis of Tie2 activation and Tie2/Tie1 heterodimerization
2017
Works of Leorah Ross being referenced
Angiopoietin-1 protects the adult vasculature against plasma leakage
2000
Vascular endothelial growth factor-trap decreases tumor burden, inhibits ascites, and causes dramatic vascular remodeling in an ovarian cancer model.
2003