Standout Papers
Citation Impact
Citing Papers
NVP-BEZ235, a Dual PI3K/mTOR Inhibitor, Prevents PI3K Signaling and Inhibits the Growth of Cancer Cells with Activating PI3K Mutations
2008
T cell metabolism drives immunity
2015
A monomeric G protein-coupled receptor isolated in a high-density lipoprotein particle efficiently activates its G protein
2007 StandoutNobel
Tumorigenesis in tuberous sclerosis complex is autophagy and p62/sequestosome 1 (SQSTM1)-dependent
2011
BAY 80-6946 Is a Highly Selective Intravenous PI3K Inhibitor with Potent p110α and p110δ Activities in Tumor Cell Lines and Xenograft Models
2013
Topological control of cytokine receptor signaling induces differential effects in hematopoiesis
2019 StandoutScienceNobel
Effects of the Dual Phosphatidylinositol 3-Kinase/Mammalian Target of Rapamycin Inhibitor NVP-BEZ235 on the Tumor Vasculature: Implications for Clinical Imaging
2008
Dual Inhibition of Class IA Phosphatidylinositol 3-Kinase and Mammalian Target of Rapamycin as a New Therapeutic Option for T-Cell Acute Lymphoblastic Leukemia
2009
Biochemical, Cellular, and In vivo Activity of Novel ATP-Competitive and Selective Inhibitors of the Mammalian Target of Rapamycin
2009
FoxO Transcription Factors Promote AKT Ser473 Phosphorylation and Renal Tumor Growth in Response to Pharmacologic Inhibition of the PI3K–AKT Pathway
2014
Phosphatidylinositol 3-Kinase Hyperactivation Results in Lapatinib Resistance that Is Reversed by the mTOR/Phosphatidylinositol 3-Kinase Inhibitor NVP-BEZ235
2008
Antimyeloma Activity of the Orally Bioavailable Dual Phosphatidylinositol 3-Kinase/Mammalian Target of Rapamycin Inhibitor NVP-BEZ235
2009
TORC1 Suppression Predicts Responsiveness to RAF and MEK Inhibition in BRAF- Mutant Melanoma
2013
The mammalian target of rapamycin regulates cholesterol biosynthetic gene expression and exhibits a rapamycin-resistant transcriptional profile
2011
Inhibition of lactate dehydrogenase A induces oxidative stress and inhibits tumor progression
2010 StandoutNobel
Antitumor Efficacy of PKI-587, a Highly Potent Dual PI3K/mTOR Kinase Inhibitor
2011
Small molecule enhancers of autophagy for neurodegenerative diseases
2008
Akt-mTORC1 signaling regulates Acly to integrate metabolic input to control of macrophage activation
2016
Dynamics of mTORC1 activation in response to amino acids
2016
Autophagy inhibition overcomes multiple mechanisms of resistance to BRAF inhibition in brain tumors
2017
Hypoxia-inducible factors and RAB22A mediate formation of microvesicles that stimulate breast cancer invasion and metastasis
2014 StandoutNobel
TSC1 Activates TGF-β-Smad2/3 Signaling in Growth Arrest and Epithelial-to-Mesenchymal Transition
2015
Protein Kinase Cθ Is Required for Autophagy in Response to Stress in the Endoplasmic Reticulum
2008
Hallmarks of Cancer: The Next Generation
2011 Standout
Feedback upregulation of HER3 (ErbB3) expression and activity attenuates antitumor effect of PI3K inhibitors
2011
Therapeutic Targeting of Autophagy
2016
Cancer Cell Metabolism
2011
The hexosamine biosynthetic pathway couples growth factor-induced glutamine uptake to glucose metabolism
2010
Targeting autophagy in obesity: from pathophysiology to management
2018
Receptor-specific Ubiquitination of β-Arrestin Directs Assembly and Targeting of Seven-transmembrane Receptor Signalosomes
2005 StandoutNobel
TOS Motif-Mediated Raptor Binding Regulates 4E-BP1 Multisite Phosphorylation and Function
2003
Chapter 2 PI3K/PTEN Signaling in Angiogenesis and Tumorigenesis
2009
Making new contacts: the mTOR network in metabolism and signalling crosstalk
2014
Regulation and function of mTOR signalling in T cell fate decisions
2012
Glutathione biosynthesis is a metabolic vulnerability in PI(3)K/Akt-driven breast cancer
2016
Role of S6K1 in regulation of SREBP1c expression in the liver
2011
Amino acid signalling upstream of mTOR
2013
The Transcription Factor Myc Controls Metabolic Reprogramming upon T Lymphocyte Activation
2011 Standout
mTOR Signaling in Growth Control and Disease
2012 Standout
mTOR Complex 1 Regulates Lipin 1 Localization to Control the SREBP Pathway
2011
Sterol regulatory element–binding proteins are essential for the metabolic programming of effector T cells and adaptive immunity
2013
A Central Role for mTOR in Lipid Homeostasis
2013
Hepatic mTORC2 Activates Glycolysis and Lipogenesis through Akt, Glucokinase, and SREBP1c
2012
Spatial Control of the TSC Complex Integrates Insulin and Nutrient Regulation of mTORC1 at the Lysosome
2014
Modular and tunable biological feedback control using a de novo protein switch
2019 StandoutNatureNobel
CD22 blockade restores homeostatic microglial phagocytosis in ageing brains
2019 StandoutNatureNobel
Drug discovery approaches targeting the PI3K/Akt pathway in cancer
2008
mTOR couples cellular nutrient sensing to organismal metabolic homeostasis
2011
The role of autophagy in neurodegenerative disease
2013 Standout
Cell Signaling by Receptor Tyrosine Kinases
2010 Standout
Exosomes and Autophagy: Coordinated Mechanisms for the Maintenance of Cellular Fitness
2014
An ATP-competitive Mammalian Target of Rapamycin Inhibitor Reveals Rapamycin-resistant Functions of mTORC1
2009 Standout
Metabolic Reprogramming by the PI3K-Akt-mTOR Pathway in Cancer
2016
Signal integration by mTORC1 coordinates nutrient input with biosynthetic output
2013
Mammalian phosphoinositide kinases and phosphatases
2009 StandoutNobel
Functions of autophagy in normal and diseased liver
2013
Inhibition of Glycogen Synthase Kinase-3 Ameliorates β-Amyloid Pathology and Restores Lysosomal Acidification and Mammalian Target of Rapamycin Activity in the Alzheimer Disease Mouse Model
2012
Inhibition of Autophagy Prevents Hippocampal Pyramidal Neuron Death after Hypoxic-Ischemic Injury
2008
Eccentric contractions increase the phosphorylation of tuberous sclerosis complex‐2 (TSC2) and alter the targeting of TSC2 and the mechanistic target of rapamycin to the lysosome
2013
Dysregulated mTORC1 renders cells critically dependent on desaturated lipids for survival under tumor-like stress
2013
The inositol 1,4,5-trisphosphate receptor regulates autophagy through its interaction with Beclin 1
2009
FUS(1-359) transgenic mice as a model of ALS: pathophysiological and molecular aspects of the proteinopathy
2018
Glutaminolysis Activates Rag-mTORC1 Signaling
2012
Insulin regulates liver metabolism in vivo in the absence of hepatic Akt and Foxo1
2012
Control of amino-acid transport by antigen receptors coordinates the metabolic reprogramming essential for T cell differentiation
2013
Autophagy fights disease through cellular self-digestion
2008 StandoutNature
18F-FDG Is a Surrogate Marker of Therapy Response and Tumor Recovery after Drug Withdrawal during Treatment with a Dual PI3K/mTOR Inhibitor in a Preclinical Model of Cisplatin-Resistant Ovarian Cancer
2013
Rapamycin: One Drug, Many Effects
2014 Standout
The multifaceted roles of fatty acid synthesis in cancer
2016
The TSC-mTOR pathway regulates macrophage polarization
2013
Tuberous Sclerosis Complex Gene Products, Tuberin and Hamartin, Control mTOR Signaling by Acting as a GTPase-Activating Protein Complex toward Rheb
2003 Standout
Akt Stimulates Hepatic SREBP1c and Lipogenesis through Parallel mTORC1-Dependent and Independent Pathways
2011
Epigallocatechin-gallate (EGCG) regulates autophagy in human retinal pigment epithelial cells: A potential role for reducing UVB light-induced retinal damage
2013
Small molecules enhance autophagy and reduce toxicity in Huntington's disease models
2007
Role of the Biomolecular Energy Gap in Protein Design, Structure, and Evolution
2012 StandoutNobel
The mTORC1 Signaling Network Senses Changes in Cellular Purine Nucleotide Levels
2017
Huntington’s disease: degradation of mutant huntingtin by autophagy
2008
Inhibition of mTOR by Rapamycin Abolishes Cognitive Deficits and Reduces Amyloid-β Levels in a Mouse Model of Alzheimer's Disease
2010
Role of autophagy in cancer
2007 Standout
GCN2 sustains mTORC1 suppression upon amino acid deprivation by inducing Sestrin2
2015
The Dawn of the Age of Amino Acid Sensors for the mTORC1 Pathway
2017
Single-Molecule Dynamics of Enhanceosome Assembly in Embryonic Stem Cells
2014 StandoutNobel
Effective and selective targeting of leukemia cells using a TORC1/2 kinase inhibitor
2010
mTOR at the nexus of nutrition, growth, ageing and disease
2020 Standout
Autophagy, Inflammation, and Immunity: A Troika Governing Cancer and Its Treatment
2016
Protein tyrosine phosphatases: from genes, to function, to disease
2006
Biological Functions of Autophagy Genes: A Disease Perspective
2019 Standout
A tuberous sclerosis complex signalling node at the peroxisome regulates mTORC1 and autophagy in response to ROS
2013
Pharmacological modulation of autophagy: therapeutic potential and persisting obstacles
2017
Kinome siRNA-phosphoproteomic screen identifies networks regulating AKT signaling
2011
mTORC1 Couples Nucleotide Synthesis to Nucleotide Demand Resulting in a Targetable Metabolic Vulnerability
2017
Recent insights into the function of autophagy in cancer
2016
The Itinerary of Autophagosomes: From Peripheral Formation to Kiss‐and‐Run Fusion with Lysosomes
2008
The PI3K pathway in B cell metabolism
2016
Phosphoinositide 3‐kinases in cell migration
2008
mTOR Signaling in Growth, Metabolism, and Disease
2017 Standout
Regulation of mTORC1 by PI3K signaling
2015
Pancreatic cancers require autophagy for tumor growth
2011
The Metabolic Profile of Tumors Depends on Both the Responsible Genetic Lesion and Tissue Type
2012 Nobel
Assaying autophagic activity in transgenic GFP-Lc3 and GFP-Gabarap zebrafish embryos
2009
Lysosomal recruitment of TSC2 is a universal response to cellular stress
2016
Physiological functions of Atg6/Beclin 1: a unique autophagy-related protein
2007
Autophagy provides metabolic substrates to maintain energy charge and nucleotide pools in Ras-driven lung cancer cells
2016
A rational mechanism for combination treatment of Huntington's disease using lithium and rapamycin
2007
Ferroptosis: An Iron-Dependent Form of Nonapoptotic Cell Death
2012 Standout
Autophagy in the Pathogenesis of Disease
2008 Standout
Paracrine Induction of HIF by Glutamate in Breast Cancer: EglN1 Senses Cysteine
2016 StandoutNobel
Lymphangioleiomyomatosis — a wolf in sheep’s clothing
2012
mTOR: from growth signal integration to cancer, diabetes and ageing
2010 Standout
Oncogenic Mutations Counteract Intrinsic Disorder in the EGFR Kinase and Promote Receptor Dimerization
2012 StandoutNobel
Inhibition of PI3K/mTOR Leads to Adaptive Resistance in Matrix-Attached Cancer Cells
2012
Autophagy: from phenomenology to molecular understanding in less than a decade
2007 Standout
Rilmenidine attenuates toxicity of polyglutamine expansions in a mouse model of Huntington's disease
2010
mTORC1 Promotes Metabolic Reprogramming by the Suppression of GSK3-Dependent Foxk1 Phosphorylation
2018
A module of negative feedback regulators defines growth factor signaling
2007
Taking dendritic cells into medicine
2007 StandoutNatureNobel
The emerging mechanisms of isoform-specific PI3K signalling
2010
The Neurology of mTOR
2014
Emerging Role of mTOR in the Response to Cancer Therapeutics
2016
MTORC1 functions as a transcriptional regulator of autophagy by preventing nuclear transport of TFEB
2012
Blocking autophagy to prevent parasite differentiation: A possible new strategy for fighting parasitic infections?
2008
Methods in Mammalian Autophagy Research
2010 Standout
Autophagy modulation as a potential therapeutic target for diverse diseases
2012 Standout
Identification of human triple-negative breast cancer subtypes and preclinical models for selection of targeted therapies
2011 Standout
mTOR Signaling in Epilepsy: Insights from Malformations of Cortical Development
2015
mTOR regulation of autophagy
2010 Standout
Growth factor-induced MAPK network topology shapes Erk response determining PC-12 cell fate
2007
The Emerging Hallmarks of Cancer Metabolism
2016 Standout
The Sestrins Interact with GATOR2 to Negatively Regulate the Amino-Acid-Sensing Pathway Upstream of mTORC1
2014
Autophagy Induction and Autophagosome Clearance in Neurons: Relationship to Autophagic Pathology in Alzheimer's Disease
2008
Anti-Vascular Endothelial Growth Factors Protect Retinal Pigment Epithelium Cells Against Oxidation by Modulating Nitric Oxide Release and Autophagy
2017 Standout
JAK2/STAT5 Inhibition Circumvents Resistance to PI3K/mTOR Blockade: A Rationale for Cotargeting These Pathways in Metastatic Breast Cancer
2012
Genome-Scale Identification of SARS-CoV-2 and Pan-coronavirus Host Factor Networks
2020 StandoutNobel
Control of TH17/Treg Balance by Hypoxia-Inducible Factor 1
2011 StandoutNobel
PTEN opposes negative selection and enables oncogenic transformation of pre-B cells
2016
PI3K in cancer: divergent roles of isoforms, modes of activation and therapeutic targeting
2014
The PtdIns(3,4)P2 phosphatase INPP4A is a suppressor of excitotoxic neuronal death
2010 StandoutNatureNobel
Autophagy and Human Disease
2007
Akt3 Deficiency in Macrophages Promotes Foam Cell Formation and Atherosclerosis in Mice
2012
Asparagine Plays a Critical Role in Regulating Cellular Adaptation to Glutamine Depletion
2014
A Lentiviral RNAi Library for Human and Mouse Genes Applied to an Arrayed Viral High-Content Screen
2006
Autophagy is a therapeutic target in anticancer drug resistance
2010
Self-eating and self-killing: crosstalk between autophagy and apoptosis
2007 Standout
Targeting autophagy in cancer
2017 Standout
A Picky Eater: Exploring the Mechanisms of Selective Autophagy in Human Pathologies
2007
AKT/PKB Signaling: Navigating the Network
2017 Standout
Repertoires of Autophagy in the Pathogenesis of Ocular Diseases
2015 Standout
The CASTOR Proteins Are Arginine Sensors for the mTORC1 Pathway
2016
Global, In Vivo, and Site-Specific Phosphorylation Dynamics in Signaling Networks
2006 Standout
Regulation of TORC1 in Response to Amino Acid Starvation via Lysosomal Recruitment of TSC2
2014
The autophagic network and cancer
2018
The PI3K Pathway in Human Disease
2017 Standout
Glutamine Sensitivity Analysis Identifies the xCT Antiporter as a Common Triple-Negative Breast Tumor Therapeutic Target
2013
Regulation of mTORC1 and its impact on gene expression at a glance
2013
Regulation of mTORC1 by amino acids
2014
Targeting PI3K signalling in cancer: opportunities, challenges and limitations
2009 Standout
PP2AT61ɛ Is an Inhibitor of MAP4K3 in Nutrient Signaling to mTOR
2010
T cell metabolic fitness in antitumor immunity
2015
Rapamycin passes the torch: a new generation of mTOR inhibitors
2011
Signaling pathways controlling skeletal muscle mass
2013
Cell-signalling dynamics in time and space
2006
Molecular logic of mTORC1 signalling as a metabolic rheostat
2019
Rapamycin and mTOR-independent autophagy inducers ameliorate toxicity of polyglutamine-expanded huntingtin and related proteinopathies
2008
PDK1-SGK1 Signaling Sustains AKT-Independent mTORC1 Activation and Confers Resistance to PI3Kα Inhibition
2016
Apoptosis blocks Beclin 1-dependent autophagosome synthesis: an effect rescued by Bcl-xL
2009
Autophagy in the liver: functions in health and disease
2017
Coordinated regulation of protein synthesis and degradation by mTORC1
2014 Nature
Everolimus for angiomyolipoma associated with tuberous sclerosis complex or sporadic lymphangioleiomyomatosis (EXIST-2): a multicentre, randomised, double-blind, placebo-controlled trial
2013
Novel targets for Huntington's disease in an mTOR-independent autophagy pathway
2008
Molecular mechanisms of mTOR-mediated translational control
2009 Standout
SLC38A9 is a component of the lysosomal amino acid sensing machinery that controls mTORC1
2015 Nature
Small Molecule Enhancers of Rapamycin-Induced TOR Inhibition Promote Autophagy, Reduce Toxicity in Huntington’s Disease Models and Enhance Killing of Mycobacteria by Macrophages
2007
With TOR, Less Is More: A Key Role for the Conserved Nutrient-Sensing TOR Pathway in Aging
2010
Principles of Cancer Therapy: Oncogene and Non-oncogene Addiction
2009 Standout
Chaperone-mediated Autophagy Targets Hypoxia-inducible Factor-1α (HIF-1α) for Lysosomal Degradation
2013 StandoutNobel
Protein clearing pathways in ALS.
2011
PTEN
2014
Autophagy: New Questions from Recent Answers
2012
Tuberous sclerosis complex: From molecular biology to novel therapeutic approaches
2016
The Transcription Factor TFEB Links mTORC1 Signaling to Transcriptional Control of Lysosome Homeostasis
2012
The Pharmacology of mTOR Inhibition
2009 Standout
Lysosomal cholesterol activates mTORC1 via an SLC38A9–Niemann-Pick C1 signaling complex
2017 Science
mTOR coordinates protein synthesis, mitochondrial activity and proliferation
2015
Pharmacologic agents targeting autophagy
2015
Regulation Mechanisms and Signaling Pathways of Autophagy
2009 Standout
Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes
2008 Standout
Role of Autophagy in Cancer Prevention
2011
NVP-BEZ235, a novel dual phosphatidylinositol 3-kinase/mammalian target of rapamycin inhibitor, elicits multifaceted antitumor activities in human gliomas
2009
Using Engineered Scaffold Interactions to Reshape MAP Kinase Pathway Signaling Dynamics
2008 Science
Differential regulation of mTORC1 by leucine and glutamine
2015 Science
mTORC1 and mTORC2 selectively regulate CD8+ T cell differentiation
2015
Autophagic substrate clearance requires activity of the syntaxin-5 SNARE complex
2011
Regulation of TFEB and V-ATPases by mTORC1
2011
Fiber Types in Mammalian Skeletal Muscles
2011 Standout
Pushing the Envelope in the mTOR Pathway: The Second Generation of Inhibitors
2011
Phase I, Dose-Escalation Study of BKM120, an Oral Pan-Class I PI3K Inhibitor, in Patients With Advanced Solid Tumors
2011
Human TKTL1 implies greater neurogenesis in frontal neocortex of modern humans than Neanderthals
2022 StandoutScienceNobel
Chemotherapy induces enrichment of CD47 + /CD73 + /PDL1 + immune evasive triple-negative breast cancer cells
2018 StandoutNobel
Regulation of Immune Responses by mTOR
2012
Assembly of Cell Regulatory Systems Through Protein Interaction Domains
2003 Science
pVHL suppresses kinase activity of Akt in a proline-hydroxylation–dependent manner
2016 StandoutScienceNobel
Amino Acid-Dependent mTORC1 Regulation by the Lysosomal Membrane Protein SLC38A9
2015
Regulation and function of the RSK family of protein kinases
2011
Pyruvate kinase M2 promotes de novo serine synthesis to sustain mTORC1 activity and cell proliferation
2012
Stimulation of de Novo Pyrimidine Synthesis by Growth Signaling Through mTOR and S6K1
2013 Science
Variegation of the Immune Response with Dendritic Cells and Pathogen Recognition Receptors
2005
2012
How do ESCRT proteins control autophagy?
2009
Specific apoptosis induction by the dual PI3K/mTor inhibitor NVP-BEZ235 in HER2 amplified and PIK3CA mutant breast cancer cells
2009
Tumor-promoting phorbol esters and activated Ras inactivate the tuberous sclerosis tumor suppressor complex via p90 ribosomal S6 kinase
2004
Cancer-derived mutations in the regulatory subunit p85α of phosphoinositide 3-kinase function through the catalytic subunit p110α
2010
Regulation of autophagy by mTOR-dependent and mTOR-independent pathways: autophagy dysfunction in neurodegenerative diseases and therapeutic application of autophagy enhancers
2013
HIF1α–dependent glycolytic pathway orchestrates a metabolic checkpoint for the differentiation of TH17 and Treg cells
2011
TFEB-mediated autophagy rescues midbrain dopamine neurons from α-synuclein toxicity
2013
A Phase II Study of BEZ235 in Patients with Everolimus-resistant, Advanced Pancreatic Neuroendocrine Tumours.
2016
mTOR inhibition activates overall protein degradation by the ubiquitin proteasome system as well as by autophagy
2015
Genome-wide CRISPR screen identifies TMEM41B as a gene required for autophagosome formation
2018
mTORC1-Activated S6K1 Phosphorylates Rictor on Threonine 1135 and Regulates mTORC2 Signaling
2009
mTOR: a pharmacologic target for autophagy regulation
2015 Standout
TORC1 inhibition enhances immune function and reduces infections in the elderly
2018
The Utilization of Extracellular Proteins as Nutrients Is Suppressed by mTORC1
2015
Ku-0063794 is a specific inhibitor of the mammalian target of rapamycin (mTOR)
2009
Quantitative Phosphoproteomics Reveal mTORC1 Activates de Novo Pyrimidine Synthesis
2013 Science
Regulation and cellular functions of class II phosphoinositide 3-kinases
2012
The intricate regulation and complex functions of the Class III phosphoinositide 3-kinase Vps34
2016
Mitochondrial activation chemicals synergize with surface receptor PD-1 blockade for T cell-dependent antitumor activity
2017 StandoutNobel
The Double-Edged Sword of Autophagy Modulation in Cancer
2009
Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation
2009 StandoutScience
mTORC1 induces purine synthesis through control of the mitochondrial tetrahydrofolate cycle
2016 Science
Regulation and function of ribosomal protein S6 kinase (S6K) within mTOR signalling networks
2011
Signalling to eIF4E in cancer
2015
The microbial mimic poly IC induces durable and protective CD4+T cell immunity together with a dendritic cell targeted vaccine
2008 StandoutNobel
Regulation of Mammalian Autophagy in Physiology and Pathophysiology
2010 Standout
mTOR signaling at a glance
2009 Standout
Works of Leon O. Murphy being referenced
Identification and characterization of NVP-BEZ235, a new orally available dual phosphatidylinositol 3-kinase/mammalian target of rapamycin inhibitor with potent in vivo antitumor activity
2008
Autophagy-Independent Lysosomal Targeting Regulated by ULK1/2-FIP200 and ATG9
2017
Sensitized RNAi screen of human kinases and phosphatases identifies new regulators of apoptosis and chemoresistance
2005
Activation of a Metabolic Gene Regulatory Network Downstream of mTOR Complex 1
2010 Standout
Molecular interpretation of ERK signal duration by immediate early gene products
2002
MAPK signal specificity: the right place at the right time
2006
Potential therapeutic applications of autophagy
2007
TBC1D7 Is a Third Subunit of the TSC1-TSC2 Complex Upstream of mTORC1
2012
Bidirectional Transport of Amino Acids Regulates mTOR and Autophagy
2009
Macroautophagy is dispensable for growth of KRAS mutant tumors and chloroquine efficacy
2015
Down-Regulation of Class II Phosphoinositide 3-Kinase α Expression below a Critical Threshold Induces Apoptotic Cell Death
2008
The E3 Ligase MuRF1 Degrades Myosin Heavy Chain Protein in Dexamethasone-Treated Skeletal Muscle
2007
RAD001 Enhances the Potency of BEZ235 to Inhibit mTOR Signaling and Tumor Growth
2012
Defective Autophagy and mTORC1 Signaling in Myotubularin Null Mice
2012
Relieving Autophagy and 4EBP1 from Rapamycin Resistance
2011
Characterization of Regulatory Events Associated with Membrane Targeting of p90 Ribosomal S6 Kinase 1
2001