Citation Impact
Citing Papers
Circulating and gut-resident human Th17 cells express CD161 and promote intestinal inflammation
2009
Programmed cell death 1 inhibits inflammatory helper T-cell development through controlling the innate immune response
2013 StandoutNobel
GPCR Engineering Yields High-Resolution Structural Insights into β 2 -Adrenergic Receptor Function
2007 StandoutScienceNobel
A Novel Germline Variant in CSF3R Reduces N-Glycosylation and Exerts Potent Oncogenic Effects in Leukemia
2018 StandoutNobel
Aggregation of embryonic stem cells induces Nanog repression and primitive endoderm differentiation
2004 StandoutNobel
Psoriasis
2009 Standout
mRNA vaccines — a new era in vaccinology
2018 StandoutNobel
Cancer nanomedicine: progress, challenges and opportunities
2016 Standout
Direct reprogramming of somatic cells is promoted by maternal transcription factor Glis1
2011 StandoutNatureNobel
Intestinal homeostasis and its breakdown in inflammatory bowel disease
2011 StandoutNature
Pathogenesis and clinical features of psoriasis
2007 Standout
Interleukin‐6: Structure‐function relationships
1997
TLR-dependent and TLR-independent pathways of type I interferon induction in systemic autoimmunity
2007 StandoutNobel
Pathogenesis and therapy of psoriasis
2007 StandoutNature
Induction of Pluripotent Stem Cells from Mouse Embryonic and Adult Fibroblast Cultures by Defined Factors
2006 StandoutNobel
How the Blood Talks to the Brain Parenchyma and the Paraventricular Nucleus of the Hypothalamus During Systemic Inflammatory and Infectious Stimuli
2000
Low-Density Lipoprotein Receptor-Related Protein-1 Mediates Endocytic Clearance of Tissue Inhibitor of Metalloproteinases-1 and Promotes Its Cytokine-Like Activities
2014 StandoutNobel
Induction of Pluripotent Stem Cells from Adult Human Fibroblasts by Defined Factors
2007 StandoutNobel
How circulating cytokines trigger the neural circuits that control the hypothalamic–pituitary–adrenal axis
2001
The ground state of embryonic stem cell self-renewal
2008 StandoutNature
Psoriasis
2021 Standout
Endocytosis-mediated downregulation of LIN-12/Notch upon Ras activation in Caenorhabditis elegans
2002 Nature
Regulated portals of entry into the cell
2003 StandoutNature
Regulated expression of gp130 and IL-6 receptor alpha chain in T cell maturation and activation
1998
High Beclin 1 expression defines a poor prognosis in endometrial adenocarcinomas
2011
Phosphorylation of Human gp130 at Ser-782 Adjacent to the Di-leucine Internalization Motif
2000
Quantitative expression of Oct-3/4 defines differentiation, dedifferentiation or self-renewal of ES cells
2000 Standout
The pathogenic role of tissue-resident immune cells in psoriasis
2007
Differential Roles for Sox15 and Sox2 in Transcriptional Control in Mouse Embryonic Stem Cells
2005 StandoutNobel
SHP2 and SOCS3 Contribute to Tyr-759-dependent Attenuation of Interleukin-6 Signaling through gp130
2002
Molecular Mechanisms of Depression: Perspectives on New Treatment Strategies
2013 Standout
Oncostatin M Regulates the Synthesis and Turnover of gp130, Leukemia Inhibitory Factor Receptor α, and Oncostatin M Receptor β by Distinct Mechanisms
2001
Progenitor cell trafficking is regulated by hypoxic gradients through HIF-1 induction of SDF-1
2004 Standout
Psoriasis
2015 Standout
Notch signalling: a simple pathway becomes complex
2006 Standout
Orientational Constraints of the gp130 Intracellular Juxtamembrane Domain for Signaling
2002
Morphogen gradient interpretation by a regulated trafficking step during ligand–receptor transduction
2005 StandoutNobel
BMP Induction of Id Proteins Suppresses Differentiation and Sustains Embryonic Stem Cell Self-Renewal in Collaboration with STAT3
2003 Standout
Autophagy in Human Health and Disease
2013 Standout
Constitutive internalization and association with adaptor protein‐2 of the interleukin‐6 signal transducer gp130
1998
Functional Expression Cloning of Nanog, a Pluripotency Sustaining Factor in Embryonic Stem Cells
2003 Standout
LRAD3, A Novel Low-Density Lipoprotein Receptor Family Member That Modulates Amyloid Precursor Protein Trafficking
2011
Taking dendritic cells into medicine
2007 StandoutNatureNobel
Structural requirements of the interleukin-6 signal transducer gp130 for its interaction with Janus kinase 1: the receptor is crucial for kinase activation
2002
The tyrosine kinase Tyk2 controls IFNAR1 cell surface expression
2003
A single amino acid substitution (Trp666→Ala) in the interbox1/2 region of the interleukin-6 signal transducer gp130 abrogates binding of JAK1, and dominantly impairs signal transduction
2000
Psoriasis: genetic associations and immune system changes
2006
STATs in cancer inflammation and immunity: a leading role for STAT3
2009 Standout
Different protein turnover of interleukin‐6‐type cytokine signalling components
1999
New cell lines from mouse epiblast share defining features with human embryonic stem cells
2007 StandoutNature
Degradation of the Epstein-Barr Virus Latent Membrane Protein 1 (LMP1) by the Ubiquitin-Proteasome Pathway
2000 StandoutNobel
Protein Kinase C δ Associates with the Interleukin-6 Receptor Subunit Glycoprotein (gp) 130 via Stat3 and Enhances Stat3-gp130 Interaction
2002
When cell biology meets development: endocytic regulation of signaling pathways
2002
Stabilizer-free poly(lactide-co-glycolide) nanoparticles for multimodal biomedical probes
2008
Convergent Mechanisms for Recognition of Divergent Cytokines by the Shared Signaling Receptor gp130
2003 StandoutNobel
Stimulation of Leukemia Inhibitory Factor Receptor Degradation by Extracellular Signal-regulated Kinase
2000
Ubiquitin Ligase Activity and Tyrosine Phosphorylation Underlie Suppression of Growth Factor Signaling by c-Cbl/Sli-1
1999 StandoutNobel
Linkage of the ubiquitin-conjugating system and the endocytic pathway in ligand-induced internalization of the growth hormone receptor
1997
Cytotoxic T Lymphocyte Antigen-4 Accumulation in the Immunological Synapse Is Regulated by TCR Signal Strength
2002 StandoutNobel
lincRNAs act in the circuitry controlling pluripotency and differentiation
2011 StandoutNature
The Homeoprotein Nanog Is Required for Maintenance of Pluripotency in Mouse Epiblast and ES Cells
2003 StandoutNobel
Maintenance of pluripotency in human and mouse embryonic stem cells through activation of Wnt signaling by a pharmacological GSK-3-specific inhibitor
2003 Standout
Secukinumab in Plaque Psoriasis — Results of Two Phase 3 Trials
2014 Standout
STATs: transcriptional control and biological impact
2002 Standout
Two Different Epitopes of the Signal Transducer gp130 Sequentially Cooperate on IL-6-Induced Receptor Activation
2000
Phorbol Esters and SDF-1 Induce Rapid Endocytosis and Down Modulation of the Chemokine Receptor CXCR4
1997
Principles of interleukin (IL)-6-type cytokine signalling and its regulation
2003 Standout
Plasmacytoid predendritic cells initiate psoriasis through interferon-α production
2005
Dendritic-cell maturation alters intracellular signaling networks, enabling differential effects of IFN-α/β on antigen cross-presentation
2006 StandoutNobel
Contributions of Leukemia Inhibitory Factor Receptor and Oncostatin M Receptor to Signal Transduction in Heterodimeric Complexes with Glycoprotein 130
1999
Identification of a Leu-Ile internalization motif within the cytoplasmic domain of the leukaemia inhibitory factor receptor
1999
A dileucine motif in the C terminus of the β 2 -adrenergic receptor is involved in receptor internalization
1997
Interleukin-6-type cytokine signalling through the gp130/Jak/STAT pathway
1998 Standout
Interferon-Stimulated Genes: A Complex Web of Host Defenses
2014 StandoutNobel
The cytoplasmic domain of the interleukin-6 receptor gp80 mediates its basolateral sorting in polarized Madin-Darby canine kidney cells
2000
Antiinflammatory Action of Glucocorticoids — New Mechanisms for Old Drugs
2005 Standout
CD28 Receptor Endocytosis Is Targeted by Mutations That Disrupt Phosphatidylinositol 3-Kinase Binding and Costimulation
1998
Fbx15 Is a Novel Target of Oct3/4 but Is Dispensable for Embryonic Stem Cell Self-Renewal and Mouse Development
2003 StandoutNobel
CTLA-4-Mediated Inhibition in Regulation of T Cell Responses: Mechanisms and Manipulation in Tumor Immunotherapy
2001 StandoutNobel
Self-renewal of pluripotent embryonic stem cells is mediated via activation of STAT3
1998
Cellular uptake of nanoparticles: journey inside the cell
2017 Standout
The Ubiquitin-Proteasome Proteolytic Pathway: Destruction for the Sake of Construction
2002 StandoutNobel
Trafficking of G Protein–Coupled Receptors
2006 StandoutNobel
The ubiquitin-proteasome system and endocytosis
1999
Signaling through a Novel Domain of gp130 Mediates Cell Proliferation and Activation of Hck and Erk Kinases
2001
Defective Internalization and Sustained Activation of Truncated Granulocyte Colony-Stimulating Factor Receptor Found in Severe Congenital Neutropenia/Acute Myeloid Leukemia
1999
Works of Leon Muys being referenced
A Di-leucine Motif and an Upstream Serine in the Interleukin-6 (IL-6) Signal Transducer gp130 Mediate Ligand-induced Endocytosis and Down-regulation of the IL-6 Receptor
1996
Memory effector (CD45RO+) and cytotoxic (CD8+) T cells appear early in the margin zone of spreading psoriatic lesions in contrast to cells expressing natural killer receptors, which appear late
2004
Internalization of the interleukin 6 signal transducer gp130 does not require activation of the Jak/STAT pathway
1998
Coupling of Biotin−(poly(ethylene glycol))amine to Poly(d ,l -lactide-co-glycolide) Nanoparticles for Versatile Surface Modification
2007
Analysis of the reliability of manual and automated immunohistochemical staining procedures. A pilot study.
2003