Citation Impact
Citing Papers
Targeting of Diacylglycerol Degradation to M1 Muscarinic Receptors by ß-Arrestins
2007 StandoutScienceNobel
Selective delivery of β cell antigen to dendritic cells in vivo leads to deletion and tolerance of autoreactive CD8 + T cells in NOD mice
2008 StandoutNobel
Enterovirus Infection, CXC Chemokine Ligand 10 (CXCL10), and CXCR3 Circuit
2009
Hallmarks of Cancer: The Next Generation
2011 Standout
ATM-dependent suppression of stress signaling reduces vascular disease in metabolic syndrome
2006
The DNA-damage response in human biology and disease
2009 StandoutNature
Identification of the residues in human CD4 critical for the binding of HIV
1989 StandoutNobel
Cloning of a putative γ-aminobutyric acid (GABA) receptor subunit ϱ3 cDNA
1996
Insulin Resistance — Mechanisms, Syndromes, and Implications
1991
ARF proteins mediate insulin-dependent activation of phospholipase D
1997
The cell biology of the insulin receptor
1989
Antibody to CMRF35-Like Molecule 2, CD300e A Novel Biomarker Detected in Patients with Fulminant Type 1 Diabetes
2016 StandoutNobel
Central nervous system control of food intake
2000 StandoutNature
The stages of type 1A diabetes: 2005
2005
The Recruitment of Raf-1 to Membranes Is Mediated by Direct Interaction with Phosphatidic Acid and Is Independent of Association with Ras
2000
The Stages of Type 1A Diabetes
2005
Immunosuppressive properties of synthetic peptides derived from CD4 and HLA-DR antigens
1988 StandoutNobel
Crystal structure of an HIV-binding recombinant fragment of human CD4
1990 StandoutNatureNobel
HIV infection does not require endocytosis of its receptor, CD4
1988 StandoutNobel
Similar reduction of first- and second-phase B-cell responses at three different glucose levels in type II diabetes and the effect of gliclazide therapy
1989
Insulin Action and the Insulin Signaling Network*
1995
soluble form of CD4 (T4) protein inhibits AIDS virus infection
1988 StandoutNatureNobel
T lymphocyte response against pancreatic beta cell antigens in fulminant Type 1 diabetes
2004
Purification and properties of the human placental insulin receptor.
1981
The LDL Receptor Gene: A Mosaic of Exons Shared with Different Proteins
1985 StandoutScienceNobel
Purification and characterization of epidermal growth factor receptor/protein kinase from normal mouse liver.
1982 StandoutNobel
CD45 regulates signal transduction and lymphocyte activation by specific association with receptor molecules on T or B cells.
1988 StandoutNobel
Molecular characteristics of recombinant human CD4 as deduced from polymorphic crystals.
1990 StandoutNobel
Expression of Toll-like Receptors in the Pancreas of Recent-onset Fulminant Type 1 Diabetes
2010
The mouse T cell receptor: Structural heterogeneity of molecules of normal T cells defined by Xenoantiserum
1983 StandoutNobel
Serotonin-Mediated Endocytosis of apCAM: an Early Step of Learning-Related Synaptic Growth in Aplysia
1992 StandoutScienceNobel
Similar control mechanisms regulate the insulin and type I insulin-like growth factor receptor kinases. Affinity-purified insulin-like growth factor I receptor kinase is activated by tyrosine phosphorylation of its beta subunit.
1986
The T4 gene encodes the AIDS virus receptor and is expressed in the immune system and the brain
1986 StandoutNobel
Purification of insulin receptor with full binding activity.
1983
On the mechanism of ligand-induced down-regulation of insulin receptor level in the liver cell.
1981
The isolation and nucleotide sequence of a cDNA encoding the T cell surface protein T4: a new member of the immunoglobulin gene family
1985 StandoutNobel
Regulation of transmembrane signaling by receptor phosphorylation
1987 StandoutNobel
Direct linkage of 125I-EGF to cell surface receptors. A useful artifact of chloramine-T treatment.
1982
Tγ protein is expressed on murine fetal thymocytes as a disulphide-linked heterodimer
1987 StandoutNatureNobel
Phorbol esters promote alpha 1-adrenergic receptor phosphorylation and receptor uncoupling from inositol phospholipid metabolism.
1985 StandoutNobel
ADP-ribosylation factor and phosphatidic acid levels in Golgi membranes during budding of coatomer-coated vesicles
1998 StandoutNobel
G-protein alpha-subunit expression, myristoylation, and membrane association in COS cells.
1990 StandoutNobel
Use of an anti-insulin receptor antibody to discriminate between metabolic and mitogenic effects of insulin: correlation with receptor autophosphorylation.
1988
Production and characterization of antibody blocking epidermal growth factor: Receptor interactions
1980
Impaired insulin secretion and glucose intolerance in synaptotagmin-7 null mutant mice
2008 StandoutNobel
Selection of an RNA molecule that mimics a major autoantigenic epitope of human insulin receptor.
1995 StandoutNobel
Internalization-defective LDL receptors produced by genes with nonsense and frameshift mutations that truncate the cytoplasmic domain
1985 StandoutNobel
Mammalian beta-adrenergic receptors. Distinct glycoprotein populations containing high mannose or complex type carbohydrate chains.
1984 StandoutNobel
Structural differences between insulin receptors in the brain and peripheral target tissues.
1983
The asialoglycoprotein receptor internalizes and recycles independently of the transferrin and insulin receptors
1983 StandoutNobel
Purification of the major protein-tyrosine-phosphatases of human placenta.
1988 StandoutNobel
Expression profiling with arrays of randomly disrupted genes in mouse embryonic stem cells leads to in vivo functional analysis
2004 StandoutNobel
Primary Structure of a Putative Receptor for a Ligand of the Insulin Family
1989
The structure of insulin receptor and its subunits. Evidence for multiple nonreduced forms and a 210,000 possible proreceptor.
1982
Endocytosis and the recycling of plasma membrane.
1983 StandoutNobel
Pure β-adrenergic receptor: the single polypeptide confers catecholamine responsiveness to adenylate cyclase
1983 StandoutNatureNobel
Cloning of the gene and cDNA for mammalian β-adrenergic receptor and homology with rhodopsin
1986 StandoutNatureNobel
Insulin activation of insulin receptor tyrosine kinase in intact rat adipocytes. An in vitro system to measure histone kinase activity of insulin receptors activated in vivo.
1986
Monoclonal antibodies reacting with multiple epitopes on the human insulin receptor
1986
The gene encoding the T-cell surface protein T4 is located on human chromosome 12.
1986 StandoutNobel
Reevaluation of the evidence that an antibody to the insulin receptor is insulinmimetic without activating the protein tyrosine kinase activity of the receptor.
1987
Syndromes of Autoimmunity and Hypoglycemia: Autoantibodies Directed Against insulinand Its Receptor
1989
Immunology of Autoimmune Thyroid Diseases
1982 Standout
Adipose Expression of Tumor Necrosis Factor-α: Direct Role in Obesity-Linked Insulin Resistance
1993 StandoutScience
Structure and expression of the human and mouse T4 genes.
1987 StandoutNobel
Insulin stimulation of phosphorylation of the beta subunit of the insulin receptor. Formation of both phosphoserine and phosphotyrosine.
1982
Antibody-induced Desensitization of the Insulin Receptor
1980
Microinjection of a protein-tyrosine-phosphatase inhibits insulin action in Xenopus oocytes.
1990 StandoutNobel
Insulin activates a tyrosine-specific protein kinase in extracts of 3T3-L1 adipocytes and human placenta.
1982
The protein-tyrosine kinase activity of the insulin receptor is necessary for insulin-mediated receptor down-regulation.
1987
Receptor-mediated phosphorylation of the hepatic insulin receptor: Evidence that the M r 95,000 receptor subunit is its own kinase
1983
[Fulminant type 1 diabetes].
2002
Tyrosine phosphorylation of the insulin receptor beta subunit activates the receptor-associated tyrosine kinase activity.
1984
daf-2 , an Insulin Receptor-Like Gene That Regulates Longevity and Diapause in Caenorhabditis elegans
1997 StandoutScienceNobel
The human LDL receptor: A cysteine-rich protein with multiple Alu sequences in its mRNA
1984 StandoutNobel
Inhibition of Insulin Receptor Binding by Phorbol Esters
1982
Internalized insulin receptors are recycled to the cell surface in rat hepatocytes.
1982
Effects of amino acid replacements within the tetrabasic cleavage site on the processing of the human insulin receptor precursor expressed in Chinese hamster ovary cells.
1990
Biosynthesis and glycosylation of the insulin receptor. Evidence for a single polypeptide precursor of the two major subunits.
1983
The human insulin receptor cDNA: The structural basis for hormone-activated transmembrane signalling
1985
Myristyl and palmityl acylation of the insulin receptor.
1987
The role of antireceptor antibodies in stimulating phosphorylation of the insulin receptor.
1984
Human placenta protein-tyrosine-phosphatase: amino acid sequence and relationship to a family of receptor-like proteins.
1989 StandoutNobel
Increased phosphorylation of ribosomal protein S6 following microinjection of insulin receptor-kinase into Xenopus oocytes
1986 StandoutNatureNobel
Prohormone processing in Xenopus oocytes: characterization of cleavage signals and cleavage enzymes.
1991 StandoutNobel
Direct demonstration of glycosylation of insulin receptor subunits by biosynthetic and external labeling: evidence for heterogeneity.
1981
DNA Damage Responses: Mechanisms and Roles in Human Disease
2008
cDNA isolated from a human T-cell library encodes a member of the protein-tyrosine-phosphatase family.
1989 StandoutNobel
Fulminant Type 1 Diabetes
2003
Subunit structure of cell surface proteins: disulfide bonding in antigen receptors, Ly-2/3 antigens, and transferrin receptors of murine T and B lymphocytes.
1981
The receptor for transepithelial transport of IgA and IgM contains multiple immunoglobulin-like domains
1984 StandoutNatureNobel
Biochemical and morphological evidence that the insulin receptor is internalized with insulin in hepatocytes.
1982
Lipid modifications of G proteins: alpha subunits are palmitoylated.
1993 StandoutNobel
Purified EGF receptor–kinase interacts specifically with antibodies to Rous sarcoma virus transforming protein
1981 StandoutNatureNobel
The Nature and Regulation of the Insulin Receptor: Structure and Function
1985
Immunoprecipitation of Insulin Receptors from Cultured Human Lymphocytes (IM-9 Cells) by Antibodies to pp60 src
1985 Science
pH and the recycling of transferrin during receptor-mediated endocytosis.
1983 StandoutNobel
Carbachol-activated muscarinic (M1 and M3) receptors transfected into Chinese hamster ovary cells inhibit trafficking of endosomes.
1991 StandoutNobel
Works of Len C. Harrison being referenced
Autoantibodies to β2-Adrenergic Receptors: a Possible Cause of Adrenergic Hyporesponsiveness in Allergic Rhinitis and Asthma
1980 Science
Changes in insulin-receptor structure associated with trypsin-induced activation of the receptor tyrosine kinase
1991
Autoantibodies Against the Insulin Receptor Recognize the Insulin Binding Subunits of an Oligomeric Receptor
1981
The human placenta contains two distinct binding and immunoreactive species of insulin-like growth factor-I receptors.
1985
Disulfide exchange between insulin and its receptor. A possible post-binding step in insulin action.
1983
Purification of the insulin receptor from human placenta by chromatography on immobilized wheat germ lectin and receptor antibody.
1980
Binding of insulin receptors to lectins: evidence for common carbohydrate determinants on several membrane receptors
1981
Immunoprecipitation of the Insulin Receptor: A Sensitive Assay for Receptor Antibodies and a Specific Technique for Receptor Purification*
1979
Treatment by Plasma Exchange of a Patient with Autoantibodies to the Insulin Receptor
1979
Receptor Biochemistry ahd Methodology
1984
A Novel Subtype of Type 1 Diabetes Mellitus
2000
Correlation between insulin receptor binding in isolated fat cells and insulin sensitivity in obese human subjects.
1976
Biosynthetic labeling of insulin receptor: studies of subunits in cultured human IM-9 lymphocytes.
1981
Insulin Receptors, Receptor Antibodies, and the Mechanism of Insulin Action
1981
Radioimmunoassay of the Insulin Receptor: A New Probe of Receptor Structure and Function
1979 Science
Gliclazide Therapy Is Associated with Potentiation of Postbinding Insulin Action in Obese, Non-insulin-dependent Diabetic Subjects
1985
Subunit structure of the insulin receptor of the human lymphocyte
1980
The binding of 125I-insulin to specific receptors in IM-9 human lymphocytes. Detection of radioactivity covalently linked to receptors.
1981
Lack of association between duration of breast-feeding or introduction of cow's milk and development of islet autoimmunity.
1999
Heterogeneity of the Insulin-Receptor Interaction in Lipoatropic Diabetes*
1981
Extreme Insulin Resistance in Ataxia Telangiectasia
1978
The Effect of Solubilization on the Properties of the Insulin Receptor of Human Placental Membranes*
1978