Lei Deng

Chimeric spike mRNA vaccines protect against Sarbecovirus challenge in mice

Single immunizations of self-amplifying or non-replicating mRNA-LNP vaccines control HPV-associated tumors in mice

Antigen modifications improve nucleoside-modified mRNA-based influenza virus vaccines in mice

Messenger RNA expressing PfCSP induces functional, protective immune responses against malaria in mice

Engineering precision nanoparticles for drug delivery

Lipid-nanoparticle-encapsulated mRNA vaccines induce protective memory CD8 T cells against a lethal viral infection

Interferon-λ enhances adaptive mucosal immunity by boosting release of thymic stromal lymphopoietin

Lipid nanoparticle chemistry determines how nucleoside base modifications alter mRNA delivery

Specific mRNA lipid nanoparticles and acquired resistance to ticks

mRNA-LNP expressing PfCSP and Pfs25 vaccine candidates targeting infection and transmission of Plasmodium falciparum

mRNA vaccines for infectious diseases: principles, delivery and clinical translation

A Multi-Targeting, Nucleoside-Modified mRNA Influenza Virus Vaccine Provides Broad Protection in Mice

Exploring in vitro expression and immune potency in mice using mRNA encoding the Plasmodium falciparum malaria antigen, CelTOS

Tick immunity using mRNA, DNA and protein-based Salp14 delivery strategies

Lyophilization provides long-term stability for a lipid nanoparticle-formulated, nucleoside-modified mRNA vaccine

mRNA vaccine with unmodified uridine induces robust type I interferon-dependent anti-tumor immunity in a melanoma model

Differential expression of interferon-lambda receptor 1 splice variants determines the magnitude of the antiviral response induced by interferon-lambda 3 in human immune cells

Eliciting B cell immunity against infectious diseases using nanovaccines

Nanomaterial Delivery Systems for mRNA Vaccines

Restoration of Motor Function through Delayed Intraspinal Delivery of Human IL-10-Encoding Nucleoside-Modified mRNA after Spinal Cord Injury

Nucleoside-Modified mRNA-Based Influenza Vaccines Circumvent Problems Associated with H3N2 Vaccine Strain Egg Adaptation

mRNA vaccination induces tick resistance and prevents transmission of the Lyme disease agent

Orientation of Antigen Display on Self-Assembling Protein Nanoparticles Influences Immunogenicity

Ionizable lipid nanoparticles deliver mRNA to pancreatic β cells via macrophage-mediated gene transfer

A multivalent nucleoside-modified mRNA vaccine against all known influenza virus subtypes

Oral Delivery of Biologics for Precision Medicine

Double-layered protein nanoparticles induce broad protection against divergent influenza A viruses

Oral delivery of Escherichia coli persistently infected with M2e-displaying bacteriophages partially protects against influenza A virus

Protein nanoparticle vaccine based on flagellin carrier fused to influenza conserved epitopes confers full protection against influenza A virus challenge

Hierarchical and Redundant Roles of Activating FcγRs in Protection against Influenza Disease by M2e-Specific IgG1 and IgG2a Antibodies

M2e-Based Universal Influenza A Vaccines