Citation Impact
Citing Papers
Probing mucin-type O-linked glycosylation in living animals
2006 StandoutNobel
SuFEx-enabled, agnostic discovery of covalent inhibitors of human neutrophil elastase
2019 StandoutNobel
In vivo imaging of hydrogen peroxide production in a murine tumor model with a chemoselective bioluminescent reporter
2010 StandoutNobel
Strategy for Dual-Analyte Luciferin Imaging: In Vivo Bioluminescence Detection of Hydrogen Peroxide and Caspase Activity in a Murine Model of Acute Inflammation
2013 StandoutNobel
The use of mRNA display to select high-affinity protein-binding peptides
2001 StandoutNobel
Efficient production of [ n ]rotaxanes by using template-directed clipping reactions
2007 StandoutNobel
Notch signalling controls pancreatic cell differentiation
1999 StandoutNatureNobel
Conversion of Xenopus Ectoderm into Neurons by NeuroD, a Basic Helix-Loop-Helix Protein
1995 Science
Direct conversion of fibroblasts to functional neurons by defined factors
2010 StandoutNatureNobel
Targeted disruption of mammalian hairy and Enhancer of split homolog-1 (HES-1) leads to up-regulation of neural helix-loop-helix factors, premature neurogenesis, and severe neural tube defects.
1995
Hierarchical Mechanisms for Direct Reprogramming of Fibroblasts to Neurons
2013 StandoutNobel
Mammalian achaete-scute homolog 1 is required for the early development of olfactory and autonomic neurons
1993
Math1-driven GFP expression in the developing nervous system of transgenic mice
2003
The WRPW Motif of the Hairy-Related Basic Helix-Loop-Helix Repressor Proteins Acts as a 4-Amino-Acid Transcription Repression and Protein-Protein Interaction Domain
1996
Epidermal Merkel cells are mechanosensory cells that tune mammalian touch receptors
2014 StandoutNatureNobel
A mechanism-based affinity-labeling agent for possible use in isolating N-acetylglucosaminidase
2001
Induced-fit catalysis of corannulene bowl-to-bowl inversion
2014 StandoutNobel
Noxious compounds activate TRPA1 ion channels through covalent modification of cysteines
2007 StandoutNatureNobel
Selection and evolution of enzymes from a partially randomized non-catalytic scaffold
2007 StandoutNatureNobel
Reaction-based small-molecule fluorescent probes for chemoselective bioimaging
2012 Standout
The Cellular Mechanism of Action of Cardiotonic Steroids: A New Hypothesis
1998
Fluorescent probes for nitric oxide and hydrogen peroxide in cell signaling
2007
extradenticle, a regulator of homeotic gene activity, is a homolog of the homeobox-containing human proto-oncogene pbx1
1993 StandoutNobel
Combinatorial and computational challenges for biocatalyst design
2001 StandoutNatureNobel
Phage display as a tool for the directed evolution of enzymes
2003
Digitalis-like compounds and Na + , K + -ATPase activity in bovine lens
1997
Recent advances in fluorescent probes for the detection of reactive oxygen species
2006
The generation of diversity and pattern in animal development
1992 StandoutNobel
The road to fully programmable protein catalysis
2022 StandoutNatureNobel
A Strategy for Functional Proteomic Analysis of Glycosidase Activity from Cell Lysates
2004 StandoutNobel
Modern reaction-based indicator systems
2009
Catalytic antibodies: hapten design strategies and screening methods
2004
Turnover-based in vitro selection and evolution of biocatalysts from a fully synthetic antibody library
2003
The origin of pattern and polarity in the Drosophila embryo
1992 StandoutNobel
The sympathoadrenal cell lineage: Specification, diversification, and new perspectives
2006
Enzymatic assembly of carbon–carbon bonds via iron-catalysed sp3 C–H functionalization
2018 StandoutNatureNobel
Genetically programmed chiral organoborane synthesis
2017 StandoutNatureNobel
High-throughput screening of enzyme libraries
2000
Fluorescent and luminescent probes for detection of reactive oxygen and nitrogen species
2011
In vitro selection of nucleic acids and proteins: what are we learning?
1999
neurogenin1 Is Essential for the Determination of Neuronal Precursors for Proximal Cranial Sensory Ganglia
1998
Bovine adrenals and hypothalamus are a major source of proscillaridin A- and ouabain-immunoreactivities
1998
Activity‐Based Protein Profiling: New Developments and Directions in Functional Proteomics
2008
Kemp elimination catalysts by computational enzyme design
2008 StandoutNatureNobel
Regulation of vertebrate neural cell fate by transcription factors
1996
Cardiotonic steroids on the road to anti-cancer therapy
2007
Profiling Enzyme Activities In Vivo Using Click Chemistry Methods
2004
Segmental expression of Hoxb-1 is controlled by a highly conserved autoregulatory loop dependent upon exd/pbx
1995 StandoutNobel
Homeobox genes and axial patterning
1992 Standout
The development and application of methods for activity-based protein profiling
2003
Mice with targeted disruptions in the paralogous genes hoxa-3 and hoxd-3 reveal synergistic interactions
1994 StandoutNatureNobel
Chemical Strategies for Functional Proteomics
2002
Man-made enzymes — from design to in vitro compartmentalisation
2000
Homeodomain-DNA recognition
1994 StandoutNobel
CRISPR-Mediated Modular RNA-Guided Regulation of Transcription in Eukaryotes
2013 StandoutNobel
Identification of neurogenin, a Vertebrate Neuronal Determination Gene
1996
Development of a long-wavelength fluorescent probe based on quinone–methide-type reaction to detect physiologically significant thiols
2008
Chemical Strategies for Activity‐Based Proteomics
2003
Evolution of Aldolase Antibodies in Vitro : Correlation of Catalytic Activity and Reaction-based Selection
2003
A strategy for the isolation of catalytic activities from repertoires of enzymes displayed on phage 1 1Edited by J. Karn
1999 StandoutNobel
Activity-based probes: discovering new biology and new drug targets
2010
Control of cell fates in the central body region of C. elegans by the homeobox gene lin-39
1993 StandoutNobel
In vitro selection and evolution of proteins
2001
Png-1, a nervous system-specific zinc finger gene, identifies regions containing postmitotic neurons during mammalian embryonic development
1997
Caged mitochondrial uncouplers that are released in response to hydrogen peroxide
2010
Mechanism-Based Profiling of Enzyme Families
2006
A Palette of Fluorescent Probes with Varying Emission Colors for Imaging Hydrogen Peroxide Signaling in Living Cells
2010
Luminescent probes for detection and imaging of hydrogen peroxide
2011
HIF-1α is required for development of the sympathetic nervous system
2019 StandoutNobel
Na + pump low and high ouabain affinity α subunit isoforms are differently distributed in cells
1997
A Selective, Cell-Permeable Optical Probe for Hydrogen Peroxide in Living Cells
2004
NMR structure determination reveals that the homeodomain is connected through a flexible linker to the main body in the Drosophila Antennapedia protein.
1992 StandoutNobel
Dynamical Contributions to Enzyme Catalysis: Critical Tests of A Popular Hypothesis
2006 StandoutNobel
Digoxin and other cardiac glycosides inhibit HIF-1α synthesis and block tumor growth
2008 StandoutNobel
A study of the reactivity of S(VI)–F containing warheads with nucleophilic amino-acid side chains under physiological conditions
2017
Detecting conserved regulatory elements with the model genome of the Japanese puffer fish, Fugu rubripes.
1995 StandoutNobel
Sodium/calcium exchange in rat cortical astrocytes
1994
Luminescent Chemodosimeters for Bioimaging
2012 Standout
PER Protein Interactions and Temperature Compensation of a Circadian Clock in Drosophila
1995 StandoutScienceNobel
Design and Synthesis of a Long-Wavelength Latent Fluorogenic Substrate for Salicylate Hydroxylase: A Useful Fluorimetric Indicator for Analyte Determination by Dehydrogenase-Coupled Biosensors
2010
Development of a Terbium Complex-Based Luminescent Probe for Imaging Endogenous Hydrogen Peroxide Generation in Plant Tissues
2011
Copper-free click chemistry for dynamic in vivo imaging
2007 StandoutNobel
Distinct domains within Mash1 and Math1 are required for function in neuronal differentiation versus neuronal cell-type specification
2004
The conserved role of Krox-20 in directing Hox gene expression during vertebrate hindbrain segmentation.
1996 StandoutNobel
Isozymes of the Na-K-ATPase: heterogeneity in structure, diversity in function
1998
Advances in the Chemistry of Tetrahydroquinolines
2011 Standout
Angiotensin II Stimulates Secretion of Endogenous Ouabain From Bovine Adrenocortical Cells via Angiotensin Type 2 Receptors
1997
Photoaffinity Probes for Studying Carbohydrate Biology
2012
Identification of two cardiac glycosides as Na(+)-pump inhibitors in rat urine and diet.
1994
Neural Science
2000 StandoutNobel
Identification of simple arylfluorosulfates as potent agents against resistant bacteria
2021 StandoutNobel
Sulfonyl fluorides as privileged warheads in chemical biology
2015
Electrostatic Basis for Enzyme Catalysis
2006 StandoutNobel
An Activity-Based Near-Infrared Glucuronide Trapping Probe for Imaging β-Glucuronidase Expression in Deep Tissues
2012
Boronate-Based Fluorescent Probes for Imaging Cellular Hydrogen Peroxide
2005
De Novo Computational Design of Retro-Aldol Enzymes
2008 StandoutScienceNobel
Regio- and stereo-selective aza-Diels–Alder reaction of ethyl glyoxylate 4-methoxyphenylimine with 1,3-dienes in the presence of BF3·Et2O. Evidence for a non-concerted mechanism
2006
Use of Quinolinium Salts in Parallel Synthesis for the Preparation of 4-Amino-2-alkyl-1,2,3,4-tetrahydroquinoline
2005
Selection approaches to catalytic systems
1997
Cu-Catalyzed Azide−Alkyne Cycloaddition
2008 StandoutNobel
Synaptic Assembly of the Brain in the Absence of Neurotransmitter Secretion
2000 StandoutScienceNobel
Sodium/Calcium Exchange: Its Physiological Implications
1999 Standout
A Strain-Promoted [3 + 2] Azide−Alkyne Cycloaddition for Covalent Modification of Biomolecules in Living Systems
2004 StandoutNobel
Diversity and Pattern in the Developing Spinal Cord
1996 Science
Design Strategies for Water-Soluble Small Molecular Chromogenic and Fluorogenic Probes
2013 Standout
Tissue-specific RNA splicing generates an ankyrin-like domain that affects the dimerization and DNA-binding properties of a bHLH protein.
1993
Critical Analysis of Antibody Catalysis
2000
Chemical Glycoproteomics
2016 StandoutNobel
Development of a sensitive long-wavelength fluorogenic probe for nitroreductase: A new fluorimetric indictor for analyte determination by dehydrogenase-coupled biosensors
2011
Works of Lee‐Chiang Lo being referenced
Mammalian achaete-scute homolog 1 is transiently expressed by spatially restricted subsets of early neuroepithelial and neural crest cells.
1991
Development of an Activity‐Based Probe for Steroid Sulfatases
2007
Na,K-ATPase Inhibitors from Bovine Hypothalamus and Human Plasma Are Different from Ouabain: Nanogram Scale CD Structural Analysis
1995
Selective activation of SHP2 activity by cisplatin revealed by a novel chemical probe-based assay
2009
Development of highly selective and sensitive probes for hydrogen peroxideElectronic supplementary information (ESI) available: general methods. See http://www.rsc.org/suppdata/cc/b3/b309393j/
2003
Design of a Mechanism‐Based Probe for Neuraminidase To Capture Influenza Viruses
2005
Chemical Selection for Catalysis in Combinatorial Antibody Libraries
1997 Science
Design and Synthesis of Activity Probes for Glycosidases
2002
Physicochemical characterization of a ouabain isomer isolated from bovine hypothalamus.
1993
Polymer-Supported Benzotriazoles as Catalysts in the Synthesis of Tetrahydroquinolines by Condensation of Aldehydes with Aromatic Amines
2001
Design and Synthesis of Class-Selective Activity Probes for Protein Tyrosine Phosphatases
2002
Design of a Mechanism‐Based Probe for Neuraminidase To Capture Influenza Viruses
2005
Synthesis and Evaluation of Activity‐Based Probes Carrying a 5′‐Fluorosulfonylbenzoyl Adenosine Moiety for Protein Kinases
2013