Standout Papers

Pleiotropic loss of activation pathways in a T-cell receptor α-chain deletion variant of a cy... 1987 2026 2000 2013 78
  1. Pleiotropic loss of activation pathways in a T-cell receptor α-chain deletion variant of a cytolytic T-cell clone (1987)
    Anne‐Marie Schmitt‐Verhulst, Annick Guimezanes et al. Nature

Citation Impact

Citing Papers

Preferential Generation of Follicular B Helper T Cells from Foxp3 + T Cells in Gut Peyer's Patches
2009 StandoutScienceNobel
Differential Antigen Processing by Dendritic Cell Subsets in Vivo
2007 StandoutScienceNobel
MYC regulates the antitumor immune response through CD47 and PD-L1
2016 Science
NK cells promote transplant tolerance by killing donor antigen-presenting cells
2006
Cutting Edge: Langerin/CD207 Receptor on Dendritic Cells Mediates Efficient Antigen Presentation on MHC I and II Products In Vivo
2008 StandoutNobel
The Mandatory Role of IL-10–Producing and OX40 Ligand-Expressing Mature Langerhans Cells in Local UVB-Induced Immunosuppression
2010
Expression of Langerin/CD207 reveals dendritic cell heterogeneity between inbred mouse strains
2008
Liposomal delivery of antigen to human dendritic cells
2003
Exogenous and endogenous glycolipid antigens activate NKT cells during microbial infections
2005 StandoutNatureNobel
S. cerevisiae α pheromone receptors activate a novel signal transduction pathway for mating partner discrimination
1991 StandoutNobel
Flt3 Signaling-Dependent Dendritic Cells Protect against Atherosclerosis
2011 StandoutNobel
Cancer nanomedicine: progress, challenges and opportunities
2016 Standout
A facile method of delivery of liposomes by nebulization
2002
The receptor DEC-205 expressed by dendritic cells and thymic epithelial cells is involved in antigen processing
1995 StandoutNatureNobel
Liposome targeting to tumors using vitamin and growth factor receptors
2000
Integrins Form an Expanding Diffusional Barrier that Coordinates Phagocytosis
2016 StandoutNobel
The level of CD8 expression can determine the outcome of thymic selection
1992 StandoutNobel
Antibody targeted gene transfer to endothelium
2002
Steady-state and inflammatory dendritic-cell development
2006
Membrane water and solute permeability determined quantitatively by self-quenching of an entrapped fluorophore
1988
The 2–5 A system: Modulation of viral and cellular processes through acceleration of RNA degradation
1998
Dendritic cells in a mature age
2006
Molecular Events Mediating T Cell Activation
1990
The hammerhead RNA domain, a model ribozyme
1993
Developmental regulation of MHC class II transport in mouse dendritic cells
1997 StandoutNatureNobel
Black, White, and Gray: Macrophages in Skin Repair and Disease
2017
Phosphorothioate analogs of 2',5'-oligoadenylate. Activation of 2',5'-oligoadenylate-dependent endoribonuclease by 2',5'-phosphorothioate cores and 5'-monophosphates
1987 StandoutNobel
Functions of natural killer cells
2008 Standout
Specialized role of migratory dendritic cells in peripheral tolerance induction
2013 Nobel
Microbial Stimulation Fully Differentiates Monocytes to DC-SIGN/CD209+ Dendritic Cells for Immune T Cell Areas
2010 StandoutNobel
Recent advances with liposomes as pharmaceutical carriers
2005 Standout
Dendritic Cell Antigen Presentation Drives Simultaneous Cytokine Production by Effector and Regulatory T Cells in Inflamed Skin
2009
Mouse Lymphoid Tissue Contains Distinct Subsets of Langerin/CD207+ Dendritic Cells, Only One of Which Represents Epidermal-Derived Langerhans Cells
2005
Production of monoclonal antibodies that recognize the extracellular domain of mouse Langerin/CD207
2007 StandoutNobel
Afferent lymph–derived T cells and DCs use different chemokine receptor CCR7–dependent routes for entry into the lymph node and intranodal migration
2011
Virosomes: evolution of the liposome as a targeted drug delivery system
2000
Distinct mRNA microarray profiles of tolerogenic dendritic cells
2001
Molecular Biology and Function of CD4 and CD8
1989
The biosynthetic pathway of MHC class II but not class I molecules intersects the endocytic route
1990
Steady state migratory RelB+ langerin+ dermal dendritic cells mediate peripheral induction of antigen‐specific CD4+CD25+Foxp3+ regulatory T cells
2011
Taking dendritic cells into medicine
2007 StandoutNatureNobel
A DNA metalloenzyme with DNA ligase activity
1995 StandoutNatureNobel
The Cell Biology of Antigen Processing and Presentation
1991
Practical design criteria for a dynamic ratio imaging system
1990 StandoutNobel
Results of a double-blind placebo-controlled study of the double-stranded RNA drug polyI:PolyC12U in the treatment of HIV infection
1996
Fluorescence ratio imaging of cyclic AMP in single cells
1991 StandoutNatureNobel
Cross‐presentation, dendritic cell subsets, and the generation of immunity to cellular antigens
2004
Virosomal adjuvanted antigen delivery systems
2003
Influenza Virosomes in Vaccine Development
2003
The origins and functions of dendritic cells and macrophages in the skin
2014
Deciphering the transcriptional network of the dendritic cell lineage
2012
Liposomes Bearing Polyethyleneglycol-Coupled Transferrin with Intracellular Targeting Property to the Solid Tumors In Vivo
2001
Origin, homeostasis and function of Langerhans cells and other langerin-expressing dendritic cells
2008
Langerhans cells protect from allergic contact dermatitis in mice by tolerizing CD8+ T cells and activating Foxp3+ regulatory T cells
2012
In vivo antigen loading and activation of dendritic cells via a liposomal peptide vaccine mediates protective antiviral and anti-tumour immunity
2000
Segregation of MHC class II molecules from MHC class I molecules in the Golgi complex for transport to lysosomal compartments
1991 Nature
Emptying of intracellular Ca2+ stores releases a novel small messenger that stimulates Ca2+ influx
1993 StandoutNatureNobel
Dendritic cell subsets in primary and secondary T cell responses at body surfaces
2009
Annexin VI is required for budding of clathrin-coated pits
1992 StandoutNobel
Template-directed synthesis of a genetic polymer in a model protocell
2008 StandoutNatureNobel
Femtosecond two‐photon high‐resolution 3D imaging, spatial‐volume rendering and microspectral characterization of immunolocalized MHC‐II and mLangerin/CD207 antigens in the mouse epidermis
2006
AID is required to initiate Nbs1/γ-H2AX focus formation and mutations at sites of class switching
2001 StandoutNatureNobel
Langerhans Cells Are Required for UVR-Induced Immunosuppression
2010
DNA Damage, Apoptosis and Langerhans Cells—Activators of UV‐induced Immune Tolerance
2008
Cross-presentation of viral and self antigens by skin-derived CD103+ dendritic cells
2009
Langerhans cells arise from monocytes in vivo
2006
A Complexin/Synaptotagmin 1 Switch Controls Fast Synaptic Vesicle Exocytosis
2006 StandoutNobel
T Cell Activation Induces Rapid Tyrosine Phosphorylation of a Limited Number of Cellular Substrates
1989
Targeted Liposomes: Convenient Coupling of Ligands to Preformed Vesicles Using “Click Chemistry”
2006
Impact of Nanotechnology on Drug Delivery
2009 Standout
Sequestration From Immune CD4 + T Cells of Mycobacteria Growing in Human Macrophages
1993 StandoutScienceNobel
Regulation by the H-2 gene complex of macrophage-lymphoid cell interactions in secondary antibody responses in vitro.
1976
Supported planar membranes in studies of cell-cell recognition in the immune system
1986
Constitutive versus Activation-dependent Cross-Presentation of Immune Complexes by CD8+ and CD8− Dendritic Cells In Vivo
2002
Peripheral CD103+ dendritic cells form a unified subset developmentally related to CD8α+ conventional dendritic cells
2010
Selective killing of transformed cells by cyclin/cyclin-dependent kinase 2 antagonists
1999 StandoutNobel
Delivery of liposomes into cultured KB cells via folate receptor-mediated endocytosis.
1994
Liposomal Delivery of CTL Epitopes to Dendritic Cells
2002
Ultraviolet B–Induced Maturation of CD11b-Type Langerin− Dendritic Cells Controls the Expansion of Foxp3+ Regulatory T Cells in the Skin
2017 StandoutNobel
Delivery of macromolecules into living cells: a method that exploits folate receptor endocytosis.
1991
Murine epidermal Langerhans cells and langerin-expressing dermal dendritic cells are unrelated and exhibit distinct functions
2009
Contingent Genetic Regulatory Events in T Lymphocyte Activation
1989 Science
Blood-derived dermal langerin+ dendritic cells survey the skin in the steady state
2007
Impaired Long-Term Potentiation, Spatial Learning, and Hippocampal Development in fyn Mutant Mice
1992 StandoutScienceNobel
Degradable Controlled-Release Polymers and Polymeric Nanoparticles: Mechanisms of Controlling Drug Release
2016 Standout
Construction of chimaeric processed immunoglobulin genes containing mouse variable and human constant region sequences
1985 StandoutNatureNobel
Comparable T helper 1 (Th1) and CD8 T-cell immunity by targeting HIV gag p24 to CD8 dendritic cells within antibodies to Langerin, DEC205, and Clec9A
2011 StandoutNobel
Functional Specificity of Thymus-Dependent Lymphocytes
1977 StandoutScienceNobel
IMMUNE RESPONSES IN VITRO
1974 StandoutNobel
Living with Clathrin: Its Role in Intracellular Membrane Traffic
1988 Science
Antitumor Monoclonal Antibodies Enhance Cross-Presentation of Cellular Antigens and the Generation of Myeloma-specific Killer T Cells by Dendritic Cells
2002
Identification of a novel population of Langerin+ dendritic cells
2007
CD207+ CD103+ dermal dendritic cells cross-present keratinocyte-derived antigens irrespective of the presence of Langerhans cells
2009
The origin and development of nonlymphoid tissue CD103+ DCs
2009
The Linkage of Innate to Adaptive Immunity via Maturing Dendritic Cells In Vivo Requires CD40 Ligation in Addition to Antigen Presentation and CD80/86 Costimulation
2004 StandoutNobel
Specific inhibition of gene expression by small double-stranded RNAs in invertebrate and vertebrate systems
2001 StandoutNobel
B cells acquire antigen from target cells after synapse formation
2001 Nature
Tat-mediated delivery of heterologous proteins into cells.
1994
Chemotherapy induces enrichment of CD47 + /CD73 + /PDL1 + immune evasive triple-negative breast cancer cells
2018 StandoutNobel
Histocompatibility-Linked Immune Response Genes
1972 StandoutScienceNobel
Th2 Lymphoproliferative Disorder of Lat Y136F Mutant Mice Unfolds Independently of TCR-MHC Engagement and Is Insensitive to the Action of Foxp3+ Regulatory T Cells
2008
Allogeneic stimulation of cytotoxic T cells by supported planar membranes.
1984
Avoiding horror autotoxicus: The importance of dendritic cells in peripheral T cell tolerance
2002 StandoutNobel
GENETIC CONTROL OF IMMUNE RESPONSES IN VITRO
1973 StandoutNobel
Wound Healing: A Cellular Perspective
2018 Standout
Tumor Rejection After Direct Costimulation of CD8 + T Cells by B7-Transfected Melanoma Cells
1993 StandoutScienceNobel
Sequential activation and lethal hit measured by [Ca2+]i in individual cytolytic T cells and targets.
1987 StandoutNobel
Clathrin: A Role in the Intracellular Retention of a Golgi Membrane Protein
1989 StandoutScienceNobel
Expression and function of the murine B7 antigen, the major costimulatory molecule expressed by peritoneal exudate cells.
1992 Nobel
Inducing Tumor Immunity through the Selective Engagement of Activating Fcγ Receptors on Dendritic Cells
2002
Brain drug delivery of small molecules using immunoliposomes
1996
Influenza virosomes as an efficient system for adjuvanted vaccine delivery
2004
Efficient Delivery of Antennapedia Homeodomain Fused to CTL Epitope with Liposomes into Dendritic Cells Results in the Activation of CD8+ T Cells
2001
Utilization of monoclonal antibodies in the treatment of leukemia and lymphoma
1982
Presentation of proteins encapsulated in sterically stabilized liposomes by dendritic cells initiates CD8+ T-cell responses in vivo
2000 StandoutNobel
Antigen Presentation and T Cell Stimulation by Dendritic Cells
2002
Nanoscale Complexity of Phospholipid Monolayers Investigated by Near-Field Scanning Optical Microscopy
1995 StandoutScienceNobel
Cu-Catalyzed Azide−Alkyne Cycloaddition
2008 StandoutNobel
Somatic Hypermutation in the Absence of DNA-Dependent Protein Kinase Catalytic Subunit (DNA-Pkcs) or Recombination-Activating Gene (Rag)1 Activity
2000
Identification, activation, and selectivein vivoablation of mouse NK cells via NKp46
2007
Regulation of the Ets-Related Transcription Factor Elf-1 by Binding to the Retinoblastoma Protein
1993 StandoutScienceNobel
Delivery of Protein Antigens to the Immune System by Fusion-Active Virosomes: A Comparison with Liposomes and ISCOMs
2002
Presentation of proteins encapsulated in sterically stabilized liposomes by dendritic cells initiates CD8+ T-cell responses in vivo
2000 StandoutNobel
The microbial mimic poly IC induces durable and protective CD4+T cell immunity together with a dendritic cell targeted vaccine
2008 StandoutNobel
In Vivo, Dendritic Cells Can Cross-Present Virus-Like Particles Using an Endosome-to-Cytosol Pathway
2003

Works of Lee Leserman being referenced

Free and Liposome-Encapsulated Double-Stranded RNAs as Inducers of Interferon, Interleukin-6, and Cellular Toxicity
1991
CD8 T Cell Help for Innate Antitumor Immunity
2007
Virosome-mediated delivery of protein antigens to dendritic cells
2002
Fusion of reconstituted influenza virus envelopes with liposomes mediated by streptavidin/biotin interactions
1996
Antibody targeted liposomes containing poly(rI) · poly(rC) exert a specific antiviral and toxic effect on cells primed with interferons α/β or γ
1989
Class I-restricted presentation of exogenous antigen acquired by Fcγ receptor-mediated endocytosis is regulated in dendritic cells
2000
Dynamics and Function of Langerhans Cells In Vivo
2005
Inhibition of cell proliferation with antibody-targeted liposomes containing methotrexate-γ-dimyristoylphosphatidylethanolamine
1988
Rapid induction of anti-idiotypic responses to unmodified monoclonal antibodies from syngeneic mice following primary immunization
1993
Efficient Presentation of Multivalent Antigens Targeted to Various Cell Surface Molecules of Dendritic Cells and Surface Ig of Antigen-Specific B Cells
1998
Weak acid-induced release of liposome-encapsulated carboxyfluorescein
1984
Induction of MHC Class I Presentation of Exogenous Antigen by Dendritic Cells Is Controlled by CD4+ T Cells Engaging Class II Molecules in Cholesterol-Rich Domains
2002
Endocytosis and recycling of MHC-encoded class II molecules by mouse B lymphocytes.
1990
Receptor-mediated endocytosis of antibody-opsonized liposomes by tumor cells.
1980
Inhibition of expression of human immunodeficiency virus-1 in vitro by antibody-targeted liposomes containing antisense RNA to the env region.
1990
Differential endocytosis of T and B lymphocyte surface molecules evaluated with antibody-bearing fluorescent liposomes containing methotrexate.
1982
Pleiotropic loss of activation pathways in a T-cell receptor α-chain deletion variant of a cytolytic T-cell clone
1987 StandoutNatureNobel
Lipid Vesicle-Cell Interactions: Analysis of a Model for Transfer of Contents from Adsorbed Vesicles to Cells
1982
Targeting to cells of fluorescent liposomes covalently coupled with monoclonal antibody or protein A
1980 Nature
Immune clearance of liposomes inhibited by an anti-Fc receptor antibody in vivo.
1986
Endocytosis of MHC molecules by B cell-B lymphoma and B cell-T lymphoma hybrids.
1986
Liposomes as drug carriers in cancer chemotherapy
1984
Monoclonal antibody covalently coupled to liposomes: Specific targeting to cells
1981
Antiviral activity in L1210 cells of liposome‐encapsulated (2′‐5′)oligo(adenylate) analogues
1985
Cell interactions in antibody formation in vitro. I. Role of the third cell in the in vitro response of spleen cells to erythrocyte antigens.
1972
Immunopurification and insertion into liposomes of native and mutant H-2Kb: quantification by solid phase radioimmunoassay
1983
Rankless by CCL
2026