Citation Impact
Citing Papers
IMF-κB and Rel: Participants in a Multiform Transcriptional Regulatory System
1993
Untangling the ErbB signalling network
2001 Standout
PNA hybridizes to complementary oligonucleotides obeying the Watson–Crick hydrogen-bonding rules
1993 StandoutNature
EGL-10 Regulates G Protein Signaling in the C. elegans Nervous System and Shares a Conserved Domain with Many Mammalian Proteins
1996 StandoutNobel
A Human Gene Encoding a Putative Basic Helix–Loop–Helix Phosphoprotein Whose mRNA Increases Rapidly in Cycloheximide-Treated Blood Mononuclear Cells
1994
Expression cloning of a cDNA encoding a retinoblastoma-binding protein with E2F-like properties
1992 StandoutNobel
Biological Activity and Biotechnological Aspects of Peptide Nucleic Acid
2006
Cellular targets for transformation by the adenovirus E1A proteins
1989
A region of SV40 large T antigen can substitute for a transforming domain of the adenovirus E1A products
1988 Nature
The T/E1A-binding domain of the retinoblastoma product can interact selectively with a sequence-specific DNA-binding protein
1991 StandoutNobel
Structural Clues to Prion Replication
1994 StandoutScienceNobel
Oncogenic Mutations Counteract Intrinsic Disorder in the EGFR Kinase and Promote Receptor Dimerization
2012 StandoutNobel
Therapeutic modulation of endogenous gene function by agents with designed DNA-sequence specificities
2003
Identification of cellular proteins that can interact specifically with the T/ElA-binding region of the retinoblastoma gene product
1991 StandoutNobel
Computational redesign of endonuclease DNA binding and cleavage specificity
2006 StandoutNatureNobel
E2F-1 Functions in Mice to Promote Apoptosis and Suppress Proliferation
1996 StandoutNobel
Dynein- and Microtubule-Mediated Translocation of Adenovirus Serotype 5 Occurs after Endosomal Lysis
2000
p53 Deficiency Rescues the Adverse Effects of Telomere Loss and Cooperates with Telomere Dysfunction to Accelerate Carcinogenesis
1999 StandoutNobel
Disrupted dichotomous intracellular control of human papillomavirus infection in cancer of the cervix
1994 StandoutNobel
Short Dysfunctional Telomeres Impair Tumorigenesis in the INK4aΔ2/3 Cancer-Prone Mouse
1999 StandoutNobel
Structural Characterization of PNA-DNA Duplexes by NMR. Evidence for DNA in a B-like Conformation
1994
Prion propagation in mice expressing human and chimeric PrP transgenes implicates the interaction of cellular PrP with another protein
1995 StandoutNobel
Cyclin A and the retinoblastoma gene product complex with a common transcription factor
1991 StandoutNatureNobel
Cell Cycle-dependent Regulation of the Cyclin B1 Promoter
1995
A role for both RB and p53 in the regulation of human cellular senescence*1
1991
Widespread long-term gene transfer to mouse skeletal muscles and heart.
1992
Preferential cytotoxicity on tumor cells by caffeic acid phenethyl ester isolated from propolis
1988
The retinoblastoma protein copurifies with E2F-I, an E1A-regulated inhibitor of the transcription factor E2F
1991
Regulating gene expression with light-activated oligonucleotides
2006
Adenovirus 5 early region 1A host range mutants hr3, hr4, and hr5 contain point mutations which generate single amino acid substitutions
1985
Different Functional Domains of the Adenovirus E1A Gene are Involved in Regulation of Host Cell Cycle Products
1987 StandoutNobel
Genetic analysis of the adenovirus E4 6/7 trans activator: interaction with E2F and induction of a stable DNA-protein complex are critical for activity
1991
Identification of separate domains in the adenovirus E1A gene for immortalization activity and the activation of virus early genes.
1986
Role of an adenovirus E2 promoter binding factor in E1A-mediated coordinate gene control.
1987
The adenovirus early region 4 open reading frame 6/7 protein regulates the DNA binding activity of the cellular transcription factor, E2F, through a direct complex.
1989
Deoxynucleic Guanidine/Peptide Nucleic Acid Chimeras: Synthesis, Binding and Invasion Studies with DNA
2000
Telomerase extends the lifespan of virus-transformed human cells without net telomere lengthening
1999 StandoutNobel
Peptide nucleic acid-targeted mutagenesis of a chromosomal gene in mouse cells
1998
The T4 gene encodes the AIDS virus receptor and is expressed in the immune system and the brain
1986 StandoutNobel
Lytic and transforming functions of individual products of the adenovirus E1A gene
1986 StandoutNobel
An adenovirus E4 gene product trans-activates E2 transcription and stimulates stable E2F binding through a direct association with E2F.
1990
The recombination signal sequence-binding protein RBP-2N functions as a transcriptional repressor.
1994 StandoutNobel
Peptide Nucleic Acid. A Molecule with Two Identities
1999
A potent transrepression domain in the retinoblastoma protein induces a cell cycle arrest when bound to E2F sites.
1995 StandoutNobel
Molecular Dynamics Simulations of PNA·DNA and PNA·RNA Duplexes in Aqueous Solution
2000
The release of growth arrest by microinjection of adenovirus E1A DNA.
1985
An adenovirus E1a protein region required for transformation and transcriptional repression
1986
The protein products of the myc and myb oncogenes and adenovirus E1a are structurally related
1983 StandoutNatureNobel
Nonionic Analogs of RNA with Dimethylene Sulfone Bridges
1996
An adenovirus early region 1A protein is required for maximal viral DNA replication in growth-arrested human cells
1985
Chiroptical Molecular Switches
2000 StandoutNobel
The new frontier of genome engineering with CRISPR-Cas9
2014 StandoutScienceNobel
Adenovirus early region 1A protein activates transcription of a nonviral gene introduced into mammalian cells by infection or transfection.
1984
Cell Cycle Control and Cancer
1994 StandoutScienceNobel
Lack of a role for transforming growth factor-β in cytotoxic T lymphocyte antigen-4-mediated inhibition of T cell activation
2001 StandoutNobel
Cyclin B2-null mice develop normally and are fertile whereas cyclin B1-null mice die in utero
1998 StandoutNobel
E2F-1-mediated transactivation is inhibited by complex formation with the retinoblastoma susceptibility gene product.
1993 StandoutNobel
The proteolysis of mitotic cyclins in mammalian cells persists from the end of mitosis until the onset of S phase.
1996 StandoutNobel
Prion protein (PrP) synthetic peptides induce cellular PrP to acquire properties of the scrapie isoform.
1995 StandoutNobel
The E1A 13S product of adenovirus 5 activates transcription of the cellular human HSP70 gene.
1986
The adenovirus E4 17-kilodalton protein complexes with the cellular transcription factor E2F, altering its DNA-binding properties and stimulating E1A-independent accumulation of E2 mRNA
1990
Double duplex invasion by peptide nucleic acid: A general principle for sequence-specific targeting of double-stranded DNA
1999
Cold-sensitive expression of transformation by a host range mutant of type 5 adenovirus.
1983
Kinetics and mechanism of polyamide ("peptide") nucleic acid binding to duplex DNA.
1995
Different functional domains of the adenovirus E1A gene are involved in regulation of host cell cycle products.
1987 StandoutNobel
Prolonged and effective blockade of tumor necrosis factor activity through adenovirus-mediated gene transfer.
1994 StandoutNobel
Complete transformation by adenovirus 2 requires both E1A proteins
1984
Oncogenes result in genomic alterations that activate a transcriptionally silent, dominantly selectable reporter gene (neo).
1992
Restoration of correct splicing in thalassemic pre-mRNA by antisense oligonucleotides.
1993
Reversible Photocontrol of Biological Systems by the Incorporation of Molecular Photoswitches
2013 StandoutNobel
Initial Stages in Infection with Animal Viruses
1982
Molecular biology of adenovirus type 2 semipermissive infections I. Viral growth and expression of viral replicative functions during restricted adenovirus infection
1986
A Field Guide to Foldamers
2001 Standout
NMR Solution Structure of a Peptide Nucleic Acid Complexed with RNA
1994 Science
Adenovirus E1A coding sequences that enable ras and pmt oncogenes to transform cultured primary cells.
1986
Ionic Effects on the Stability and Conformation of Peptide Nucleic Acid Complexes
1996
Predicted alpha-helical regions of the prion protein when synthesized as peptides form amyloid.
1992 StandoutNobel
Reversible Optical Transcription of Supramolecular Chirality into Molecular Chirality
2004 StandoutScienceNobel
Enzymatic synthesis of DNA on glycerol nucleic acid templates without stable duplex formation between product and template
2007 StandoutNobel
Adenovirus E1B 19-kilodalton protein overcomes the cytotoxicity of E1A proteins
1991
PD-loop: A complex of duplex DNA with an oligonucleotide
1998
Regulation of the Interleukin (IL)-12R β2 Subunit Expression in Developing T Helper 1 (Th1) and Th2 Cells
1997
Deregulated transcription factor E2F-1 expression leads to S-phase entry and p53-mediated apoptosis.
1994 StandoutNobel
The Recombination Signal Sequence-Binding Protein RBP-2N Functions as a Transcriptional Repressor
1994 StandoutNobel
Inhibitors of human immunodeficiency virus integrase.
1993 StandoutNobel
Peptide Nucleic Acids with a Conformationally Constrained Chiral Cyclohexyl‐Derived Backbone
1997
Independent regions of adenovirus E1A are required for binding to and dissociation of E2F-protein complexes.
1993
Functional domains of adenovirus type 5 E1a proteins
1987
Molecular Biology of Prion Diseases
1991 StandoutScienceNobel
Adenovirus E1A Coding Sequences That Enable ras and pmt Oncogenes To Transform Cultured Primary Cells
1986
Regulation of the Ets-Related Transcription Factor Elf-1 by Binding to the Retinoblastoma Protein
1993 StandoutScienceNobel
THE UBIQUITIN SYSTEM
1998 StandoutNobel
Inhibitors of the proteasome pathway interfere with induction of nitric oxide synthase in macrophages by blocking activation of transcription factor NF-kappa B.
1996 StandoutNobel
Evidence that a second tumor antigen coded by adenovirus early gene region E1a is required for efficient cell transformation.
1985
Identification of Separate Domains in the Adenovirus E1A Gene for Immortalization Activity and the Activation of Virus Early Genes
1986
COOH-terminal sequence of the cellular prion protein directs subcellular trafficking and controls conversion into the scrapie isoform
1997 StandoutNobel
Identification of a negative regulatory domain in the human papillomavirus type 18 promoter: interaction with the transcriptional repressor YY1.
1992 StandoutNobel
Systemic delivery of antisense oligoribonucleotide restores dystrophin expression in body-wide skeletal muscles
2004 StandoutNobel
E3 ubiquitin ligase Mindbomb 1 facilitates nuclear delivery of adenovirus genomes
2020 StandoutNobel
Recombinant scrapie-like prion protein of 106 amino acids is soluble
1996 StandoutNobel
Conversion of truncated and elongated prion proteins into the scrapie isoform in cultured cells.
1993 StandoutNobel
Dissection of overlapping functions within the adenovirus type 5 E1A gene.
1984
A Nucleic Acid Triple Helix Formed by a Peptide Nucleic Acid-DNA Complex
1995 Science
Adenovirus E4-dependent activation of the early E2 promoter is insufficient to promote the early-to-late-phase transition
1991
Works of Lee E. Babiss being referenced
An assessment of the antisense properties of RNase H-competent and steric-blocking oligomers
1995
Impact of biophysical parameters on the biological assessment of peptide nucleic acids, antisense inhibitors of gene expression
1995
Accelerated onset of viral transcription in adenovirus-infected HeLa cells treated with the tumor promoter 12-O-tetradecanoyl-phorbol-13-acetate.
1984
Promoter of the adenovirus polypeptide IX gene: similarity to E1B and inactivation by substitution of the simian virus 40 TATA element
1991
Cellular Promoters Incorporated into the Adenovirus Genome: Cell Specificity of Albumin and Immunoglobulin Expression
1986
Antisense DNA downregulation of the ERBB2 oncogene measured by a flow cytometric assay.
1995
The mouse albumin enhancer contains a negative regulatory element that interacts with a novel DNA-binding protein.
1990
Deletion and insertion mutations in early region 1a of type 5 adenovirus that produce cold-sensitive or defective phenotypes for transformation
1984
Reovirus serotypes 1 and 3 differ in their in vitro association with microtubules
1979
Transformation properties of type 5 adenovirus mutants that differentially express the E1A gene products.
1984
The efficiency of adenovirus transformation of rodent cells is inversely related to the rate of viral E1A gene expression
1990
Changes in NF-kappa B and ISGF3 DNA binding activities are responsible for differences in MHC and beta-IFN gene expression in Ad5- versus Ad12-transformed cells.
1991
Analysis of type 5 adenovirus transformation with a cloned rat embryo cell line (CREF).
1982
The Mouse Albumin Enhancer Contains a Negative Regulatory Element That Interacts with a Novel DNA-Binding Protein
1990
Antisense and Antigene Properties of Peptide Nucleic Acids
1992 Science
The cellular transcription factor E2f requires viral E1A and E4 gene products for increased DNA-binding activity and functions to stimulate adenovirus E2A gene expression
1989
Upstream Stimulatory Factor Regulates Expression of the Cell Cycle-Dependent Cyclin B1 Gene Promoter
1995
Induced expression of the endogenous beta interferon gene in adenovirus type 5-transformed rat fibroblasts
1992
Strand-invasion of duplex DNA by peptide nucleic acid oligomers.
1993
Accelerated Onset of Viral Transcription in Adenovirus-Infected HeLa Cells Treated with the Tumor Promoter 12-O-Tetradecanoyl-Phorbol-13-Acetate
1984