Citation Impact
Citing Papers
High-Throughput Mapping of a Dynamic Signaling Network in Mammalian Cells
2005 StandoutScience
The tumor suppressor LKB1 kinase directly activates AMP-activated kinase and regulates apoptosis in response to energy stress
2004 Standout
Cd44 Enhances Neuregulin Signaling by Schwann Cells
2000
Comprehensive genomic characterization defines human glioblastoma genes and core pathways
2008 StandoutNature
Homozygous Inactivation of theNF1Gene in Bone Marrow Cells from Children with Neurofibromatosis Type 1 and Malignant Myeloid Disorders
1997
Differential roles of human Dicer-binding proteins TRBP and PACT in small RNA processing
2013 StandoutNobel
Acromegaly
2006 Standout
Switching of the coupling of the β2-adrenergic receptor to different G proteins by protein kinase A
1997 StandoutNatureNobel
Proteins regulating Ras and its relatives
1993 StandoutNature
CD44: From adhesion molecules to signalling regulators
2003 Standout
NHE-RF, a Regulatory Cofactor for Na+-H+Exchange, Is a Common Interactor for Merlin and ERM (MERM) Proteins
1998
The von Hippel–Lindau tumour suppressor protein: O2 sensing and cancer
2008 StandoutNobel
Mice heterozygous for a mutation at the Nf2 tumor suppressor locus develop a range of highly metastatic tumors
1998
How Tumors Become Angiogenic
1996
The Neurofibromatosis-2 homologue, Merlin, and the tumor suppressor expanded function together in Drosophila to regulate cell proliferation and differentiation
2000
Patterns and Emerging Mechanisms of the Angiogenic Switch during Tumorigenesis
1996 Standout
Prolyl hydroxylase 3 (PHD3) is essential for hypoxic regulation of neutrophilic inflammation in humans and mice
2011 StandoutNobel
Functional Analysis of the Neurofibromatosis Type 2 Protein by Means of Disease-Causing Point Mutations
2000
Cancer Metastasis: Building a Framework
2006 Standout
Structure of the ERM Protein Moesin Reveals the FERM Domain Fold Masked by an Extended Actin Binding Tail Domain
2000
Cushing's syndrome
2015 Standout
Lung Cancer
2008 Standout
ERM proteins and merlin: integrators at the cell cortex
2002 Standout
Male-driven evolution
2002
Molecular defects in the pathogenesis of pituitary tumours
2003
Targeted expression of MYCN causes neuroblastoma in transgenic mice
1997
Neuroblastoma: biological insights into a clinical enigma
2003 Standout
Transformation of hematopoietic cell lines to growth-factor independence and induction of a fatal myelo- and lymphoproliferative disease in mice by retrovirally transduced TEL/JAK2 fusion genes
1998
Interdomain Interaction of Merlin Isoforms and Its Influence on Intermolecular Binding to NHE-RF
1999
The small GTP-binding proteins Rac1 and Cdc42regulate the activity of the JNK/SAPK signaling pathway
1995 Standout
Angiogenesis in cancer and other diseases
2000 StandoutNature
The Hallmarks of Cancer
2000 Standout
Rho, Rac, and Cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia, and filopodia
1995 Standout
Hippo Pathway in Organ Size Control, Tissue Homeostasis, and Cancer
2015 Standout
Ezrin, radixin, and moesin are components of Schwann cell microvilli
2001
Role of the retinoblastoma protein in the pathogenesis of human cancer.
1997 StandoutNobel
Ezrin function is required for ROCK-mediated fibroblast transformation by the Net and Dbl oncogenes
2000
Merlin, a Tumor Suppressor, Interacts with Transactivation-responsive RNA-binding Protein and Inhibits Its Oncogenic Activity
2004
DNA Methylation Markers and Early Recurrence in Stage I Lung Cancer
2008
The retinoblastoma gene in human pituitary tumors.
1993
G Protein-coupled Receptor Kinase 6A Phosphorylates the Na+/H+ Exchanger Regulatory Factor via a PDZ Domain-mediated Interaction
1999 StandoutNobel
The neurofibromatosis 2 protein product merlin selectively binds F-actin but not G-actin, and stabilizes the filaments through a lateral association
2001
NF2: The wizardry of merlin
2003
ERM proteins and NF2 tumor suppressor: the Yin and Yang of cortical actin organization and cell growth signaling
2002
Schwann cell hyperplasia and tumors in transgenic mice expressing a naturally occurring mutant NF2 protein
1999
The NF2 interactor, hepatocyte growth factor-regulated tyrosine kinase substrate (HRS), associates with merlin in the 'open' conformation and suppresses cell growth and motility
2001
The Nf2 Tumor Suppressor, Merlin, Functions in Rac-Dependent Signaling
2001
Initial sequence of the chimpanzee genome and comparison with the human genome
2005 StandoutNature
Malignant Gliomas in Adults
2008 Standout
Protein modules and signalling networks
1995 StandoutNature
Mutations in PIK3CAare infrequent in neuroblastoma
2006
A tiger behind many doors: multiple genetic pathways to malignant glioma
1995
Regulation of the Neurofibromatosis Type 2 Tumor Suppressor Protein, Merlin, by Adhesion and Growth Arrest Stimuli
1998
Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes
2002 Standout
Ras-dependent Mitogen-activated Protein Kinase Activation by G Protein-coupled Receptors
1997 StandoutNobel
A novel moesin-, ezrin-, radixin-like gene is a candidate for the neurofibromatosis 2 tumor suppressor
1993 Standout
p73 is a human p53-related protein that can induce apoptosis
1997 StandoutNatureNobel
Neuroblastoma
2007 Standout
Radiotherapy plus Concomitant and Adjuvant Temozolomide for Glioblastoma
2005 Standout
Primary brain tumours in adults
2012 Standout
Rho and Rac Take Center Stage
2004 Standout
Cushing's syndrome
2006 Standout
Molecular genetic analysis of familial neuroblastoma
1997
Integrins
2002 Standout
Molecular characterization of chromosome 22 deletions in schwannomas
1992
Human DNA methylomes at base resolution show widespread epigenomic differences
2009 StandoutNature
The structure of the FERM domain of merlin, the neurofibromatosis type 2 gene product
2002
Gβγ Subunits Mediate Src-dependent Phosphorylation of the Epidermal Growth Factor Receptor
1997 StandoutNobel
A Gain-of-Function Mutation of JAK2 in Myeloproliferative Disorders
2005 Standout
Site-specific DNA methylation in the neurofibromatosis (NF1) promoter interferes with binding of CREB and SP1 transcription factors
1999
Biology and Genetics of Human Neuroblastomas
1997
Brain Tumors
2001 Standout
Genetic Causes of Brain Tumors: Neurofibromatosis, Tuberous Sclerosis, von Hippel-Lindau, and Other Syndromes
2007
The kinesin KIF1Bβ acts downstream from EglN3 to induce apoptosis and is a potential 1p36 tumor suppressor
2008 StandoutNobel
Neuroblast differentiation during development and in neuroblastoma requires KIF1Bβ-mediated transport of TRKA
2017
Merlin differentially associates with the microtubule and actin cytoskeleton
1998
Biology of the p21-Activated Kinases
2003
Structural Analysis of Drosophila Merlin Reveals Functional Domains Important for Growth Control and Subcellular Localization
1998
Development of a histological pseudocapsule and its use as a surgical capsule in the excision of pituitary tumors
2006
A Family of cAMP-Binding Proteins That Directly Activate Rap1
1998 StandoutScience
Absence of p53 gene mutations in primary neuroblastomas.
1993
EglN3 hydroxylase stabilizes BIM-EL linking VHL type 2C mutations to pheochromocytoma pathogenesis and chemotherapy resistance
2019 StandoutNobel
Janus Kinases and Focal Adhesion Kinases Play in the 4.1 Band: A Superfamily of Band 4.1 Domains Important for Cell Structure and Signal Transduction
1998
Pigment Epithelium-Derived Factor: A Potent Inhibitor of Angiogenesis
1999 StandoutScience
The Molecular Pathogenesis of Corticotroph Tumors
1999
RNA Scanning of a Molecular Machine with a Built-in Ruler
2016 StandoutNobel
Molecular Biology of Neuroblastoma
1999
Homozygous deletion of CDKN2A (p16INK4a/p14ARF) but not within 1p36 or at other tumor suppressor loci in neuroblastoma.
2001
Clonal origins of adrenocorticotropin-secreting pituitary tissue in Cushing's disease.
1992
The Nf2 tumor suppressor gene product is essential for extraembryonic development immediately prior to gastrulation.
1997
ERM-Merlin and EBP50 Protein Families in Plasma Membrane Organization and Function
2000
Integrating Genetic Approaches into the Discovery of Anticancer Drugs
1997 StandoutScienceNobel
Malignant glioma: genetics and biology of a grave matter
2001
A C-terminal motif found in the β 2 -adrenergic receptor, P2Y1 receptor and cystic fibrosis transmembrane conductance regulator determines binding to the Na + /H + exchanger regulatory factor family of PDZ proteins
1998 StandoutNobel
Human pituitary adenomas show no loss of heterozygosity at the retinoblastoma gene locus.
1994
SMART, a simple modular architecture research tool: Identification of signaling domains
1998 Standout
Population-based analysis of sporadic and type 2 neurofibromatosis-associated meningiomas and schwannomas
2000
Elimination of residual metastatic prostate cancer after surgery and adjunctive cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) blockade immunotherapy
1999 StandoutNobel
Works of Lee B. Jacoby being referenced
Molecular Analysis of the NF2 Tumor-Suppressor Gene in Schwannomatosis
1997
Frequency and distribution ofNF2 mutations in schwannomas
1996
The parental origin of new mutations in neurofibromatosis 2
2000
Neurofibromatosis 2: loss of merlin's protective spell
1996
Clonal origin of pituitary adenomas
1990
Merlin: the neurofibromatosis 2 tumor suppressor
1999
Neurofibromatosis type 1 gene mutations in neuroblastoma
1993
Clonal Analysis of a Case of Multiple Meningiomas Using Multiple Molecular Genetic Approaches: Pathology Case Report
1999
Exon scanning for mutation of the NF2 gene in schwannomas
1994
Analysis of the neurofibromatosis 2 gene in human ependymomas and astrocytomas.
1994
Clonal analysis of human meningiomas and schwannomas.
1990
CD44 expression is aberrant in benign Schwann cell tumors possessing mutations in the neurofibromatosis type 2, but not type 1, gene.
1997
Mutational analysis of patients with neurofibromatosis 2.
1994