Standout Papers
Citation Impact
Citing Papers
Semipermeable lipid bilayers exhibit diastereoselectivity favoring ribose
2005 StandoutNobel
Ribozyme self-replication?
1989 StandoutNatureNobel
Efficient catalysis of polycytidylic acid-directed oligoguanylate formation by Pb2+
1980
Chiral selection in poly(C)-directed synthesis of oligo(G)
1984 Nature
Genetic variability of the AIDS virus: Nucleotide sequence analysis of two isolates from African patients
1986 StandoutNobel
Selection and evolution of enzymes from a partially randomized non-catalytic scaffold
2007 StandoutNatureNobel
Ribozyme-catalysed amino-acid transfer reactions
1996 StandoutNatureNobel
In vitro evolution suggests multiple origins for the hammerhead ribozyme
2001 StandoutNatureNobel
Non-enzymatic transcription of an oligodeoxynucleotide 14 residues long
1987
The guanosine binding site of the Tetrahymena ribozyme
1989 StandoutNatureNobel
Simplified proteins: minimalist solutions to the ‘protein folding problem’
1998 StandoutNobel
Rapid Evolution of RNA Viruses
1987
RNA-catalysed synthesis of complementary-strand RNA
1989 StandoutNatureNobel
In vitro selection of RNA molecules that bind specific ligands
1990 StandoutNatureNobel
Synthesis of RNA oligomers on heterogeneous templates
1996 Nature
Reverse self-splicing of the tetrahymena group I intron: Implication for the directionality of splicing and for intron transposition
1989 StandoutNobel
Chemical self-replication of palindromic duplex DNA
1994 Nature
In vitro evolution of a self-alkylatlng ribozyme
1995 StandoutNatureNobel
Synthesizing life
2001 StandoutNatureNobel
In vitro evolution of new ribozymes with polynucleotide kinase activity
1994 StandoutNatureNobel
A telomeric sequence in the RNA of Tetrahymena telomerase required for telomere repeat synthesis
1989 StandoutNatureNobel
DNA‐Templated Organic Synthesis: Nature's Strategy for Controlling Chemical Reactivity Applied to Synthetic Molecules
2004 Standout
Structurally Complex and Highly Active RNA Ligases Derived from Random RNA Sequences
1995 StandoutScienceNobel
An RNA motif that binds ATP
1993 StandoutNatureNobel
Template-directed synthesis of a genetic polymer in a model protocell
2008 StandoutNatureNobel
RNA evolution and the origins of life
1989 Nature
Molecular replication
1992 Nature
A model for the RNA-catalyzed replication of RNA.
1986 StandoutNobel
Template-Directed Primer Extension Catalyzed by the Tetrahymena Ribozyme
1991 StandoutNobel
Comparison of the virulent Asibi strain of yellow fever virus with the 17D vaccine strain derived from it.
1987 StandoutNobel
Stereochemistry of RNA Cleavage by the Tetrahymena Ribozyme and Evidence that the Chemical Step Is Not Rate-Limiting
1989 StandoutScienceNobel
The search for the chemistry of life's origin
2007
Ein selbstreplierendes Hexadesoxynucleotid
1986
A general two-metal-ion mechanism for catalytic RNA.
1993 StandoutNobel
Boundary structures are formed by organic components of the Murchison carbonaceous chondrite
1985 Nature
Non-enzymatic template-directed synthesis on RNA random copolymers
1984
Circular RNAs: relics of precellular evolution?
1989
Specificity of template-directed synthesis with adenine nucleosides
1970 StandoutNobel
Coupling of Tetrahymena Ribosomal RNA Splicing to β-Galactosidase Expression in Escherichia coli
1985 StandoutScienceNobel
Crystallographic and biochemical investigation of the lead(II)-catalyzed hydrolysis of yeast phenylalanine tRNA
1985
Oligomerization of activated d - and l -guanosine mononucleotides on templates containing d - and l -deoxycytidylate residues
1998
Rna catalysis and the origin of life
1985
Template-directed primer extension catalyzed by the Tetrahymena ribozyme.
1991 StandoutNobel
Kinetic and Mechanistic Analysis of Nonenzymatic, Template-Directed Oligoribonucleotide Ligation
1996 StandoutNobel
One binding site determines sequence specificity of Tetrahymena pre-rRNA self-splicing, trans-splicing, and RNA enzyme activity
1986 StandoutNobel
Nonenzymatic, Template-Directed Ligation of Oligoribonucleotides Is Highly Regioselective for the Formation of 3‘−5‘ Phosphodiester Bonds
1996 StandoutNobel
Nonenzymic Joining of Oligoadenylates on a Polyuridylic Acid Template
1976 Science
Selection of circularization sites in a group I IVS RNA requires multiple alignments of an internal template-like sequence
1987 StandoutNobel
How many catalytic RNAs? Ions and the Cheshire cat conjecture.
1993
RNA as an RNA Polymerase: Net Elongation of an RNA Primer Catalyzed by the Tetrahymena Ribozyme
1988 StandoutScienceNobel
The Chemistry of Self-Splicing RNA and RNA Enzymes
1987 StandoutScienceNobel
Native protein sequences are close to optimal for their structures
2000 StandoutNobel
The Intervening Sequence RNA of Tetrahymena Is an Enzyme
1986 StandoutScienceNobel
Template catalysis of acetyl transfer reactions
1971
A Labile Phosphodiester Bond at the Ligation Junction in a Circular Intervening Sequence RNA
1984 StandoutScienceNobel
Specific interaction between the self-splicing RNA of Tetrahymena and its guanosine substrate: implications for biological catalysis by RNA
1984 StandoutNatureNobel
Ligation of oligonucleotides by pyrimidine dimers—a missing ‘link’ in the origin of life?
1982 Nature
A Multisubunit Ribozyme That Is a Catalyst of and Template for Complementary Strand RNA synthesis
1991 StandoutScienceNobel
Reactions of adenosine 5′-phosphorimidazolide with adenosine analogs on a polyuridylic acid template
1977
Reversibility of cyclization of the tetrahymena rRNA intervening sequence: implication for the mechanism of splice site choice
1985 StandoutNobel
The Tetrahymena ribozyme acts like an RNA restriction endonuclease
1986 StandoutNatureNobel
RNA catalysis and the origins of life
1986
Rapid Evolution of RNA Genomes
1982 StandoutScience
Speculations on the early course of evolution.
1986
Stereochemical Course of Catalysis by the Tetrahymena Ribozyme
1989 StandoutScienceNobel
Template-directed synthesis on the pentanucleotide CpCpGpCpC
1984
Selforganization of matter and the evolution of biological macromolecules
1971 Standout
Sindbis Virus: An Efficient, Broad Host Range Vector for Gene Expression in Animal Cells
1989 StandoutScienceNobel
Template-Directed Synthesis Using the Heterogeneous Templates Produced by Montmorillonite Catalysis. A Possible Bridge Between the Prebiotic and RNA Worlds
1997
Experimental Models of Primitive Cellular Compartments: Encapsulation, Growth, and Division
2003 StandoutScienceNobel
Studies in prebiotic synthesis
1972
Condensation of activated diguanylates on a poly(C) template
1981
Nonenzymatic Synthesis of RNA and DNA Oligomers on Hexitol Nucleic Acid Templates: The Importance of the A Structure
1999
Mechanism of recognition of the 5′ splice site in self-splicing group I introns
1986 StandoutNatureNobel
Enzymatic activity of the conserved core of a group I self-splicing intron
1986 StandoutNatureNobel
Selection of a Ribozyme That Functions as a Superior Template in a Self-Copying Reaction
1992 StandoutScienceNobel
DNA-Templated Dimerization of Hairpin Polyamides
2003
LAV Revisited: Origins of the Early HIV-1 Isolates from Institut Pasteur
1991 StandoutScienceNobel
Intermolecular exon ligation of the rRNA precursor of tetrahymena: Oligonucleotides can function as 5′ exons
1985 StandoutNobel
Template-directed synthesis on oligodeoxycytidylate and polydeoxycytidylate templates
1985
Oligomerization of (guanosine 5′-phosphor)-2-methylimidazolide on poly(C)
1982
Works of L.E. Orgel being referenced
Directed panspermia
1973
Non-enzymic oligonucleotide synthesis on a polycytidylate template
1969 StandoutNobel
Non-enzymic synthesis of deoxyadenylate oligonucleotides on a polyuridylate template
1968 StandoutNobel
Catalysis of accurate poly(C)-directed synthesis of 3′-5′-linked oligoguanylates by Zn2+
1980
Efficient Metal-Ion Catalyzed Template-Directed Oligonucleotide Synthesis
1980 Science
A Nonenzymatic RNA Polymerase Model
1983 Science
Studies in prebiotic synthesis
1970