Citation Impact
Citing Papers
ATP in the mechanotransduction pathway of normal human chondrocytes
2004
Experimental models of inflammatory bowel disease
1995 Standout
Properties of Osteoconductive Biomaterials: Calcium Phosphates
2002 Standout
Infantile hypophosphatasia: Treatment options to control hypercalcemia, hypercalciuria, and chronic bone demineralization
1997
Activators and target genes of Rel/NF-κB transcription factors
1999 Standout
Nucleotides released by apoptotic cells act as a find-me signal to promote phagocytic clearance
2009 StandoutNature
Overview of mammalian zinc transporters
2004
The Clinical Sequelae of Intravascular Hemolysis and Extracellular Plasma Hemoglobin
2005 Standout
Alkaline phosphatase: placental and tissue-nonspecific isoenzymes hydrolyze phosphoethanolamine, inorganic pyrophosphate, and pyridoxal 5'-phosphate. Substrate accumulation in carriers of hypophosphatasia corrects during pregnancy.
1995
Selective activation of nociceptors by P2X receptor agonists in normal and inflamed rat skin
2001
ATP in human skin elicits a dose-related pain response which is potentiated under conditions of hyperalgesia
2000
Cellular function and molecular structure of ecto-nucleotidases
2012
Sjögren's syndrome
2005 Standout
Dietary emulsifiers impact the mouse gut microbiota promoting colitis and metabolic syndrome
2015 StandoutNature
Molecular Mechanism of Basic Calcium Phosphate Crystal-induced Activation of Human Fibroblasts
1998
Nucleotide signalling during inflammation
2014 StandoutNature
Interleukin-1 Induces Pro-Mineralizing Activity of Cartilage Tissue Transglutaminase and Factor XIIIa
2001
P2X receptor‐mediated excitation of nociceptive afferents in the normal and arthritic rat knee joint
1998
Serum and plasma inhibit neutrophil stimulation by hydroxyapatite crystals. evidence that serum αl2‐hs glycoprotein is a potent and specific crystal‐bound inhibitor
1988
Synovial fluid analysis
2005
Peptidoglycan- and Lipoteichoic Acid-induced Cell Activation Is Mediated by Toll-like Receptor 2
1999 Standout
Selective spider toxins reveal a role for the Nav1.1 channel in mechanical pain
2016 StandoutNatureNobel
Expression of adenosine triphosphate P2X3 receptors in rat molar pulp and trigeminal ganglia
2002
Early Immunologic Failure is Associated With Early Mortality Among Advanced HIV–Infected Adults Initiating Antiretroviral Therapy With Active Tuberculosis
2013 StandoutNobel
Juvenile idiopathic arthritis
2007 Standout
Physiological and pathophysiological functions of the ecto-nucleotide pyrophosphatase/phosphodiesterase family
2003
Dietary chitosan inhibits hypercholesterolaemia and atherogenesis in the apolipoprotein E-deficient mouse model of atherosclerosis
1998
Induction of NO Synthesis by Lipoteichoic Acid fromStaphylococcus aureusin J774 Macrophages: Involvement of a CD14-Dependent Pathway
1997
Ophidian envenomation strategies and the role of purines
2002
Gout
2009 Standout
Development of a severity score for CRPS
2010
The new bone biology: Pathologic, molecular, and clinical correlates
2006
Acute Pancreatitis
2016 Standout
Mechanisms underlying enhanced P2X receptor-mediated responses in the neuropathic pain state
2005
Porosity of 3D biomaterial scaffolds and osteogenesis
2005 Standout
Pathophysiology and Therapeutic Potential of Purinergic Signaling
2006
Cellular Distribution and Functions of P2 Receptor Subtypes in Different Systems
2004
Ankylosing spondylitis
2007 Standout
Delayed examination of synovial fluid by ordinary and polarised light microscopy to detect and identify crystals
2002
Transglutaminases: crosslinking enzymes with pleiotropic functions
2003 Standout
K+ Efflux Is the Common Trigger of NLRP3 Inflammasome Activation by Bacterial Toxins and Particulate Matter
2013 Standout
COMP (Cartilage Oligomeric Matrix Protein) is Synthesized in Ligament, Tendon, Meniscus, and Articular Cartilage
1998
The P2Y agonist UTP activates cutaneous afferent fibers
2004
Gout
2016 Standout
Pannexin 1 channels mediate ‘find-me’ signal release and membrane permeability during apoptosis
2010 StandoutNature
Gout in the Elderly
1998
Signs and symptoms of reflex sympathetic dystrophy: prospective study of 829 patients
1993 Standout
Trigeminal P2X3 receptor expression differs from dorsal root ganglion and is modulated by deep tissue inflammation
2005
The immunology of stroke: from mechanisms to translation
2011 Standout
Physiology and Pathophysiology of Purinergic Neurotransmission
2007 Standout
Reflex sympathetic dystrophy of the hand: an excessive inflammatory response?
1993
Hypophosphatasia and the Role of Alkaline Phosphatase in Skeletal Mineralization*
1994
Chitosan as a Nasal Delivery System: The Effect of Chitosan Solutions on in Vitro and in Vivo Mucociliary Transport Rates in Human Turbinates and Volunteers
1997
The juvenile-onset spondyloarthritides
2002
Faster Rate of Initial Fluid Resuscitation in Severe Acute Pancreatitis Diminishes In-Hospital Mortality
2009
Sterile inflammation: sensing and reacting to damage
2010 Standout
Differential mechanisms of inorganic pyrophosphate production by plasma cell membrane glycoprotein-1 and B10 in chondrocytes
1999
The many roles of histone deacetylases in development and physiology: implications for disease and therapy
2008 Standout
The serum protein α2–Heremans-Schmid glycoprotein/fetuin-A is a systemically acting inhibitor of ectopic calcification
2003 Standout
Targeted Deletion of Metalloproteinase 9 Attenuates Experimental Colitis in Mice: Central Role of Epithelial-Derived MMP
2005
2‐Chloroadenosine but not adenosine induces apoptosis in rheumatoid fibroblasts independently of cell surface adenosine receptor signalling
2002 StandoutNobel
Febuxostat Compared with Allopurinol in Patients with Hyperuricemia and Gout
2005 Standout
Efficacy of allopurinol and benzbromarone for the control of hyperuricaemia. A pathogenic approach to the treatment of primary chronic gout
1998
Inflammatory bowel disease: Etiology and pathogenesis
1998 Standout
Radiographic assessment of sacroiliitis by radiologists and rheumatologists: does training improve quality?
2003
Objectification of the Diagnostic Criteria for CRPS: Table 1
2010
Intracellular Retention and Degradation of Tissue-Nonspecific Alkaline Phosphatase with a Gly317→Asp Substitution Associated with Lethal Hypophosphatasia
1998 StandoutNobel
Causal link between nucleotide pyrophosphohydrolase overactivity and increased intracellular inorganic pyrophosphate generation demonstrated by transfection of cultured fibroblasts and osteoblasts with plasma cell membrane glycoprotein–1
1994
Adenosine 5′-triphosphate and adenosine as endogenous signaling molecules in immunity and inflammation
2006
Hypophosphatasia and the Extracellular Metabolism of Inorganic Pyrophosphate: Clinical and Laboratory Aspects: Part I
1991
Fluid Resuscitation in Acute Pancreatitis
2008
ATP as a peripheral mediator of pain
2000
Phosphate-Induced Vascular Calcification
2004
Purine Catabolic Enzymes in Human Synovial Fluids
1989
Common mutations F310L and T1559del in the tissue-nonspecific alkaline phosphatase gene are related to distinct phenotypes in Japanese patients with hypophosphatasia
2005 StandoutNobel
Validation of proposed diagnostic criteria (the “Budapest Criteria”) for Complex Regional Pain Syndrome
2010 Standout
Up-regulated expression of the phosphodiesterase nucleotide pyrophosphatase family member PC-1 is a marker and pathogenic factor for knee meniscal cartilage matrix calcification
2001
Severe hypercalcaemia and respiratory insufficiency associated with infantile hypophosphatasia caused by two novel mutations of the tissue-nonspecific alkaline phosphatase gene
2000
ATP and UTP activate calcium-mobilizing P2U-like receptors and act synergistically with interleukin-1 to stimulate prostaglandin E2 release from human rheumatoid synovial cells
1998
Primary Sjögren's Syndrome with Central Nervous System Disease Mimicking Multiple Sclerosis
1986
Continuing Worldwide Increase in Tropospheric Methane, 1978 to 1987
1988 StandoutScienceNobel
Osteoinduction in the Presence of Chitosan-Coated Porous Hydroxyapatite
1995
Exosomes
2019 Standout
Soluble CD141–152 Confers Responsiveness to Both Lipoarabinomannan and Lipopolysaccharide in a Novel HL-60 Cell Bioassay
1998
Role of the Mouse ank Gene in Control of Tissue Calcification and Arthritis
2000 Science
The production of methane from solid wastes
1987 StandoutNobel
Tissue-nonspecific alkaline phosphatase and plasma cell membrane glycoprotein-1 are central antagonistic regulators of bone mineralization
2002 Standout
Molecular Physiology of P2X Receptors
2002 Standout
Hapten-Induced Model of Chronic Inflammation and Ulceration in the Rat Colon
1989 Standout
Osteoblast tissue-nonspecific alkaline phosphatase antagonizes and regulates PC-1
2000
Human primary fibroblasts in vitro express a purinergic P2X7 receptor coupled to ion fluxes, microvesicle formation and IL-6 release
1999
Intradermal tophi in gout: a case-control study.
1999
Matrix Vesicle Plasma Cell Membrane Glycoprotein-1 Regulates Mineralization by Murine Osteoblastic MC3T3 Cells
1999
Neuropathic Pain: From Mechanisms to Treatment
2020 Standout
Birth and Death of Bone Cells: Basic Regulatory Mechanisms and Implications for the Pathogenesis and Treatment of Osteoporosis*
2000 Standout
Functional Characterization of Osteoblasts and Osteoclasts from Alkaline Phosphatase Knockout Mice
2000
Ectonucleotidases: Some recent developments and a note on nomenclature
2001
The role of matrix vesicles in growth plate development and biomineralization
2005
Interannual Variability of Atmospheric Methane: Possible Effects of the El Niño—Southern Oscillation
1986 Science
The effect of control and self-medication of chronic gout in a developing country. Outcome after 10 years.
2003
Enzyme replacement therapy for infantile hypophosphatasia attempted by intravenous infusions of alkaline phosphatase-rich Paget plasma: Results in three additional patients
1984
Granulomatous enterocolitis induced in rats by purified bacterial cell wall fragments
1985
Clinical Aspects of Calcium Pyrophosphate Dihydrate Crystal Deposition
1988
The kidneys in paroxysmal nocturnal hemoglobinuria
1981
Osteoarthritis: New Insights. Part 1: The Disease and Its Risk Factors
2000 Standout
Vascular Calcification
2008 Standout
Chitosan Chemistry and Pharmaceutical Perspectives
2004 Standout
Role of Extracellular Matrix in Adaptation of Tendon and Skeletal Muscle to Mechanical Loading
2004 Standout
Infantile hypophosphatasia: Normalization of circulating bone alkaline phosphatase activity followed by skeletal remineralization
1986
Metals in Neurobiology: Probing Their Chemistry and Biology with Molecular Imaging
2008 Standout
NLRP3 inflammasome plays a critical role in the pathogenesis of hydroxyapatite-associated arthropathy
2011
Physiology of Microglia
2011 Standout
Immunogenic Cell Death in Cancer Therapy
2012 Standout
Different missense mutations at the tissue-nonspecific alkaline phosphatase gene locus in autosomal recessively inherited forms of mild and severe hypophosphatasia.
1992
P2X Receptors and Nociception
2001
Possible interference between tissue-non-specific alkaline phosphatase with an Arg54→Cys substitution and a counterpart with an Asp277→Ala substitution found in a compound heterozygote associated with severe hypophosphatasia
2000 StandoutNobel
Works of Lawrence M. Ryan being referenced
Molecular cloning and expression of a porcine chondrocyte nucleotide pyrophosphohydrolase
1997
Basic calcium phosphate crystals induce synthesis and secretion of 92 kDa gelatinase (gelatinase B/matrix metalloprotease 9) in human fibroblasts
1998
Characterization of binding and TNF-α-inducing ability of chitosans on monocytes: the involvement of CD14
1994
Articular Cartilage Vesicles Generate Calcium Pyrophosphate Dihydrate‐Like Crystals in Vitro
1992
Phosphocitrate blocks nitric oxide-induced calcification of cartilage and chondrocyte-derived apoptotic bodies
1999
Insulin-like growth factor-1 suppresses pyrophosphate elaboration by transforming growth factor β1-stimulated chondrocytes and cartilage
1994
Stimulation of Cartilage Inorganic Pyrophosphate Elaboration by Ascorbate
1991
Up‐regulated expression of cartilage intermediate‐layer protein and ANK in articular hyaline cartilage from patients with calcium pyrophosphate dihydrate crystal deposition disease
2002
Basic calcium phosphate crystal-induced collagenase production: role of intracellular crystal dissolution
1998
A unique ectonucleotide pyrophosphohydrolase associated with porcine chondrocyte-derived vesicles.
1995
Mutations in the amino terminus of ANKH in two US families with calcium pyrophosphate dihydrate crystal deposition disease
2003
Cartilage inorganic pyrophosphate elaboration is independent of sulfated glycosaminoglycan synthesis
1990
The ank gene story
2000
Understanding inorganic pyrophosphate metabolism: toward prevention of calcium pyrophosphate dihydrate crystal deposition.
1995
ATP‐induced chondrocalcinosis
1992
Comparison of Matrix Vesicles Derived from Normal and Osteoarthritic Human Articular Cartilage
1996
Synovial fluid inorganic pyrophosphate concentration and nucleotide pyrophosphohydrolase activity in basic calcium phosphate deposition arthropathy and milwaukee shoulder syndrome
1988
Synovial fluid and plasma levels of cartilage matrix glycoprotein in arthritis
1994
Differential deoxyadenosine toxicity to immature rabbit cartilage in vitro. a model for the chondro‐osseous dysplasia of adenosine deaminase deficiency
1989
Comparative calcification of native articular cartilage matrix vesicles and nitroprusside-generated vesicles
2002
Human Osteoarthritic Cartilage Matrix Vesicles Generate Both Calcium Pyrophosphate Dihydrate and ApatiteIn Vitro
1998
Cellular Responses to Whitlockite
1999
Cartilage nucleoside triphosphate pyrophosphohydrolase. II. role in extracellular pyrophosphate generation and nucleotide metabolism
1985
The Radiographic Diagnosis of Sacroiliitis
1983
Alkaline Phosphatase Knock-Out Mice Recapitulate the Metabolic and Skeletal Defects of Infantile Hypophosphatasia
1999
The reflex sympathetic dystrophy syndrome (RSDS)
1981
Transforming growth factor β1 stimulates inorganic pyrophosphate elaboration by porcine cartilage
1991
Inorganic Pyrophosphate Metabolism in Arthritis
1988
Cartilage Nucleoside Triphosphate (NTP) Pyrophosphohydrolase
1984
TREATMENT OF REFRACTORY CRYSTAL-ASSOCIATED ARTHRITIS
1995
Adenosine triphosphate pyrophosphohydrolase and neutral inorganic pyrophosphatase in pathologic joint fluids. Elevated pyrophosphohydrolase in calcium pyrophosphate dihydrate crystal deposition disease
1985
Infantile hypophosphatasia: Enzyme replacement therapy by intravenous infusion of alkaline phosphatase-rich plasma from patients with Paget bone disease
1982
Quantification of human plasma inorganic pyrophosphate
1979
Milwaukee shoulder syndrome: Eleven additional cases with involvement of the knee in seven (basic calcium phosphate crystal deposition disease)
1984
Characterization of an additional articular cartilage vesicle fraction that generates calcium pyrophosphate dihydrate crystals in vitro.
1995
Probenecid inhibits transforming growth factor-beta 1 induced pyrophosphate elaboration by chondrocytes.
1994
Calcium pyrophosphate crystal deposition disease ; pseudogout ; articular chondrocalcinosis
1993
Release of Pyrophosphate by Normal Mammalian Articular Hyaline and Fibrocartilage in Organ Culture
1981
Acute erosive reactive arthritis associated with campylobacter jejuni-lnduced colitis
1984
Ecto-Nucleoside Triphosphate Pyrophosphohydrolase Activity and Calcium Pyrophosphate Dihydrate Crystal Deposition Disease
1986
Hypertonic saline attenuates end-organ damage in an experimental model of acute pancreatitis
2000
Reply
1984
Inorganic pyrophosphate levels in blood platelets from normal donors and patients with calcium pyrophosphate dihydrate crystal deposition disease
1983
Synovial fluid ATP: a potential substrate for the production of inorganic pyrophosphate.
1991
Amyloid arthropathy: possible association with chondrocalcinosis.
1982
Partial characterization of synovial fluid nucleotide pyrophosphohydrolase
1985
Renal proximal tubular dysfunction and paroxysmal nocturnal hemoglobinuria
1977
Adenosine triphosphate levels in human plasma.
1996
Marrow Cell Transplantation for Infantile Hypophosphatasia
2003