Citation Impact
Citing Papers
Species-Specific Recognition of Single-Stranded RNA via Toll-like Receptor 7 and 8
2004 StandoutScience
Innate Antiviral Responses by Means of TLR7-Mediated Recognition of Single-Stranded RNA
2004 StandoutScience
Assay of locus-specific genetic load implicates rare Toll-like receptor 4 mutations in meningococcal susceptibility
2003 StandoutNobel
Dishevelled 2 Recruits ß-Arrestin 2 to Mediate Wnt5A-Stimulated Endocytosis of Frizzled 4
2003 StandoutScienceNobel
Keeping G Proteins at Bay: A Complex Between G Protein-Coupled Receptor Kinase 2 and Gßγ
2003 StandoutScienceNobel
Role of Adaptor TRIF in the MyD88-Independent Toll-Like Receptor Signaling Pathway
2003 StandoutScience
Hallmarks of Cancer: The Next Generation
2011 Standout
Regulation of signal transduction by endocytosis
2000
A Toll-like receptor recognizes bacterial DNA
2000 StandoutNature
Recognition of double-stranded RNA and activation of NF-κB by Toll-like receptor 3
2001 StandoutNature
Innate immune sensing and its roots: the story of endotoxin
2003 StandoutNobel
Multiple Roles for Rsp5p-dependent Ubiquitination at the Internalization Step of Endocytosis
2001
Classical and new roles of β-arrestins in the regulation of G-PROTEIN-COUPLED receptors
2001 StandoutNobel
Unravelling the pathogenesis of inflammatory bowel disease
2007 StandoutNature
Accessory factors in clathrin-dependent synaptic vesicle endocytosis
2000
Bacterial CpG-DNA and lipopolysaccharides activate Toll-like receptors at distinct cellular compartments
2002
Protein regulation by monoubiquitin
2001
The innate immune response to bacterial flagellin is mediated by Toll-like receptor 5
2001 StandoutNature
Endocytosis of G protein-coupled receptors: roles of G protein-coupled receptor kinases and ß-arrestin proteins
2002
Monoubiquitin carries a novel internalization signal that is appended to activated receptors
2000
Sequential Activation of Signaling Pathways during Innate Immune Responses in Drosophila
2002
Activation of the transcription factor MEF2C by the MAP kinase p38 in inflammation
1997 Nature
Regulated portals of entry into the cell
2003 StandoutNature
Epidermal Growth Factor (EGF) Receptor-dependent ERK Activation by G Protein-coupled Receptors
2001 StandoutNobel
Unresponsiveness of MyD88-Deficient Mice to Endotoxin
1999 Standout
Heme Oxygenase-1/Carbon Monoxide: From Basic Science to Therapeutic Applications
2006 Standout
Chediak–Higashi Syndrome: A Rare Disorder of Lysosomes and Lysosome Related Organelles
2002
Toll-like receptors in the induction of the innate immune response
2000 StandoutNature
The β2-Adrenergic Receptor Mediates Extracellular Signal-regulated Kinase Activation via Assembly of a Multi-receptor Complex with the Epidermal Growth Factor Receptor
2000 StandoutNobel
Carbon monoxide has anti-inflammatory effects involving the mitogen-activated protein kinase pathway
2000 Standout
Signaling on the Endocytic Pathway
2001
Oncogenic Mutations Counteract Intrinsic Disorder in the EGFR Kinase and Promote Receptor Dimerization
2012 StandoutNobel
β-Arrestin1 Interacts with the Catalytic Domain of the Tyrosine Kinase c-SRC
2000 StandoutNobel
The immune response of Drosophila
2003 StandoutNatureNobel
A TRP Channel that Senses Cold Stimuli and Menthol
2002 StandoutNobel
Origin and physiological roles of inflammation
2008 StandoutNature
Mammalian MAP kinase signalling cascades
2001 StandoutNature
Identification of Lps2 as a key transducer of MyD88-independent TIR signalling
2003 StandoutNatureNobel
When cell biology meets development: endocytic regulation of signaling pathways
2002
Trk receptors: mediators of neurotrophin action
2001 StandoutNobel
Src-dependent Tyrosine Phosphorylation Regulates Dynamin Self-assembly and Ligand-induced Endocytosis of the Epidermal Growth Factor Receptor
2002 StandoutNobel
Pathogen Recognition and Innate Immunity
2006 Standout
β-Arrestin inhibits NF-κB activity by means of its interaction with the NF-κB inhibitor IκBα
2004 StandoutNobel
Relationships between EGFR Signaling–competent and Endocytosis-competent Membrane Microdomains
2005
Genetically encoded reporters of protein kinase A activity reveal impact of substrate tethering
2001 StandoutNobel
Mice with mutations of Dock7 have generalized hypopigmentation and white-spotting but show normal neurological function
2009 StandoutNobel
Neurotrophins: Roles in Neuronal Development and Function
2001 Standout
Signaling via Src family kinases is required for normal internalization of the receptor c-Kit.
1999
β-Arrestin 2: A Receptor-Regulated MAPK Scaffold for the Activation of JNK3
2000 StandoutScienceNobel
β-Arrestin1 modulates lymphoid enhancer factor transcriptional activity through interaction with phosphorylated dishevelled proteins
2001 StandoutNobel
Avoiding horror autotoxicus: The importance of dendritic cells in peripheral T cell tolerance
2002 StandoutNobel
Contact-dependent inhibition of EGFR signaling by Nf2/Merlin
2007
The Dendritic Cell Receptor for Endocytosis, Dec-205, Can Recycle and Enhance Antigen Presentation via Major Histocompatibility Complex Class II–Positive Lysosomal Compartments
2000 StandoutNobel
Functional antagonism of different G protein-coupled receptor kinases for β-arrestin-mediated angiotensin II receptor signaling
2005 StandoutNobel
Details of Toll-like receptor:adapter interaction revealed by germ-line mutagenesis
2006 StandoutNobel
Activation and targeting of extracellular signal-regulated kinases by β-arrestin scaffolds
2001 StandoutNobel
Toll-like receptors 9 and 3 as essential components of innate immune defense against mouse cytomegalovirus infection
2004 StandoutNobel
Genetically encoded fluorescent reporters of protein tyrosine kinase activities in living cells
2001 StandoutNobel
Toll‐like receptors: molecular mechanisms of the mammalian immune response
2000
The Ubiquitin-Proteasome Proteolytic Pathway: Destruction for the Sake of Construction
2002 StandoutNobel
Heme oxygenase/carbon monoxide signaling pathways: Regulation and functional significance
2002
The function of the Drosophila fat facets deubiquitinating enzyme in limiting photoreceptor cell number is intimately associated with endocytosis
2000
Biological Basket Weaving: Formation and Function of Clathrin-Coated Vesicles
2001
HIV-1-infected monocyte-derived dendritic cells do not undergo maturation but can elicit IL-10 production and T cell regulation
2004 StandoutNobel
The WD40 and FYVE domain containing protein 2 defines a class of early endosomes necessary for endocytosis
2006 StandoutNobel
Bacterial endotoxin stimulates macrophages to release HMGB1 partly through CD14- and TNF-dependent mechanisms
2004
Plant and Animal Sensors of Conserved Microbial Signatures
2010 StandoutScienceNobel
CpG-DNA-specific activation of antigen-presenting cells requires stress kinase activity and is preceded by non-specific endocytosis and endosomal maturation
1998
NGF Signals through TrkA to Increase Clathrin at the Plasma Membrane and Enhance Clathrin-Mediated Membrane Trafficking
2000
Lipopolysaccharide Activates Distinct Signaling Pathways in Intestinal Epithelial Cell Lines Expressing Toll-Like Receptors
2000
Quantitative Imaging of Lateral ErbB1 Receptor Signal Propagation in the Plasma Membrane
2000 Science
ß-Arrestin 2 Mediates Endocytosis of Type III TGF-ß Receptor and Down-Regulation of Its Signaling
2003 StandoutScienceNobel
Transduction of Receptor Signals by ß-Arrestins
2005 StandoutScienceNobel
Works of Lawrence Lem being referenced
EGF Receptor Signaling Stimulates SRC Kinase Phosphorylation of Clathrin, Influencing Clathrin Redistribution and EGF Uptake
1999
Enhanced Interaction of HLA-DM with HLA-DR in Enlarged Vacuoles of Hereditary and Infectious Lysosomal Diseases
1999
Activation of c-Jun N-terminal kinase in bacterial lipopolysaccharide-stimulated macrophages.
1996