Citation Impact
Citing Papers
Neurotoxic protein expression reveals connections between the circadian clock and mating behavior in Drosophila
2006 StandoutNobel
Normal gut microbiota modulates brain development and behavior
2011 Standout
The 2.6 Angstrom Crystal Structure of a Human A 2A Adenosine Receptor Bound to an Antagonist
2008 StandoutScience
Mutant G-protein-coupled receptors as a cause of human diseases
2004
Cellular Inclusion Bodies of Mutant Huntingtin Exon 1 Obscure Small Fibrillar Aggregate Species
2012 StandoutNobel
AMPK regulates energy expenditure by modulating NAD+ metabolism and SIRT1 activity
2009 StandoutNature
The DNA-damage response in human biology and disease
2009 StandoutNature
Acute and chronic restraint stress alter the incidence of social conflict in male rats
2003
Parkin Facilitates the Elimination of Expanded Polyglutamine Proteins and Leads to Preservation of Proteasome Function
2003
Prevention of cytosolic IAPs degradation: a potential pharmacological target in Huntington's Disease
2005
Apoptosis in the nervous system
2000 StandoutNature
Adenosine receptors and Huntington's disease: implications for pathogenesis and therapeutics
2003
The Ubiquitin Proteasome System in Neurodegenerative Diseases
2003 StandoutNobel
Progressive depletion of complexin II in a transgenic mouse model of Huntington's disease
2001
Cholinergic agonists inhibit HMGB1 release and improve survival in experimental sepsis
2004 Standout
The Blood-Brain Barrier in Health and Chronic Neurodegenerative Disorders
2008 Standout
Loss of normal huntingtin function: new developments in Huntington's disease research
2001
Excitotoxic Neuronal Death and the Pathogenesis of Huntington's Disease
2008
Proteases Acting on Mutant Huntingtin Generate Cleaved Products that Differentially Build Up Cytoplasmic and Nuclear Inclusions
2002
Molecular genetics: Unmasking polyglutamine triggers in neurodegenerative disease
2000
Huntington's disease
2007 Standout
Inhibition of mTOR induces autophagy and reduces toxicity of polyglutamine expansions in fly and mouse models of Huntington disease
2004 Standout
Physiology and Neurobiology of Stress and Adaptation: Central Role of the Brain
2007 Standout
Forebrain ependymal cells are Notch-dependent and generate neuroblasts and astrocytes after stroke
2009 StandoutNobel
Inclusion body formation reduces levels of mutant huntingtin and the risk of neuronal death
2004 StandoutNature
Huntingtin has a membrane association signal that can modulate huntingtin aggregation, nuclear entry and toxicity
2007
The Lifelong Effects of Early Childhood Adversity and Toxic Stress
2011 Standout
Nuclear Localization of a Non-caspase Truncation Product of Atrophin-1, with an Expanded Polyglutamine Repeat, Increases Cellular Toxicity
2003
Cytoplasmic retention of polyglutamine-expanded androgen receptor ameliorates disease via autophagy in a mouse model of spinal and bulbar muscular atrophy
2009
Mechanisms and consequences of impaired lipid trafficking in Niemann–Pick type C1-deficient mammalian cells
2009
Behavioral Phenotyping Strategies for Mutant Mice
2008
Reversal of Neuropathology and Motor Dysfunction in a Conditional Model of Huntington's Disease
2000
Role of α-synuclein in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced parkinsonism in mice
2003 StandoutNobel
Mutant huntingtin's interaction with mitochondrial protein Drp1 impairs mitochondrial biogenesis and causes defective axonal transport and synaptic degeneration in Huntington's disease
2011
Clinical and molecular advances in autosomal dominant cerebellar ataxias: from genotype to phenotype and physiopathology
2000
Nitric Oxide and Peroxynitrite in Health and Disease
2007 Standout
Endoplasmic reticulum stress: cell life and death decisions
2005 Standout
Mitochondria: In Sickness and in Health
2012 Standout
Coupling endoplasmic reticulum stress to the cell death program
2004
Super-Enhancers in the Control of Cell Identity and Disease
2013 Standout
p53 Mediates Cellular Dysfunction and Behavioral Abnormalities in Huntington’s Disease
2005
Structure of the human M2 muscarinic acetylcholine receptor bound to an antagonist
2012 StandoutNatureNobel
The Rise and Fall of the Chemoattractant Receptor GPR33
2005 StandoutNobel
Blinded by the Light: The Growing Complexity of p53
2009 Standout
Oxidative stress and mitochondrial dysfunction in neurodegenerative diseases
2007
Protein aggregation and neurodegenerative disease
2004 Standout
Protein degradation and protection against misfolded or damaged proteins
2003 StandoutNature
Four deaths and a funeral: from caspases to alternative mechanisms
2001 Standout
Endoplasmic Reticulum Stress and the Inflammatory Basis of Metabolic Disease
2010 Standout
Glial and neuronal expression of polyglutamine proteins induce behavioral changes and aggregate formation in Drosophila
2004
Delaying the onset of Huntington's in mice
2000 Nature
Neural consequences of enviromental enrichment
2000 Standout
Stress and the brain: from adaptation to disease
2005 Standout
Autophagy in Human Health and Disease
2013 Standout
A Rapid Cellular FRET Assay of Polyglutamine Aggregation Identifies a Novel Inhibitor
2003
Copper-Zinc Superoxide Dismutase (SOD1) Is Released by Microglial Cells and Confers Neuroprotection against 6-OHDA Neurotoxicity
2012 Standout
A gene expression atlas of the central nervous system based on bacterial artificial chromosomes
2003 StandoutNature
Adult Neurogenesis in the Mammalian Brain: Significant Answers and Significant Questions
2011 Standout
The Charcot–Marie–Tooth type 2A gene product, Mfn2, up-regulates fuel oxidation through expression of OXPHOS system
2005
Forkhead box protein p1 is a transcriptional repressor of immune signaling in the CNS: implications for transcriptional dysregulation in Huntington disease
2012
Mitochondrial Membrane Permeabilization in Cell Death
2007 Standout
Serial analysis of gene expression predicts structural differences in hippocampus of long attack latency and short attack latency mice
2003
Mitochondrial dysfunction and oxidative stress in neurodegenerative diseases
2006 StandoutNature
Lessons from animal models of Huntington's disease
2002
The PtdIns(3,4)P2 phosphatase INPP4A is a suppressor of excitotoxic neuronal death
2010 StandoutNatureNobel
Features of trinucleotide repeat instability in vivo
2008
Early mitochondrial calcium defects in Huntington's disease are a direct effect of polyglutamines
2002
CHOP induces death by promoting protein synthesis and oxidation in the stressed endoplasmic reticulum
2004 Standout
Cleavage at the Caspase-6 Site Is Required for Neuronal Dysfunction and Degeneration Due to Mutant Huntingtin
2006
The biopsychosocial approach to chronic pain: Scientific advances and future directions.
2007 Standout
Muscarinic acetylcholine receptors: mutant mice provide new insights for drug development
2007
Endosome maturation
2011 Standout
Repertoires of Autophagy in the Pathogenesis of Ocular Diseases
2015 Standout
Misfolded proteins, endoplasmic reticulum stress and neurodegeneration
2004
Reduced activity and protein expression of NOS in R6/2 HD transgenic mice: effects of l-NAME on symptom progression
2001
Reversing Neurodegeneration:A Promise Unfolds
2000
Autophagy: process and function
2007 Standout
The Darwinian concept of stress: benefits of allostasis and costs of allostatic load and the trade-offs in health and disease
2004
Structure and dynamics of the M3 muscarinic acetylcholine receptor
2012 StandoutNatureNobel
Bac to the future: The use of bac transgenic mice for neuroscience research
2001
The Role of Protein Composition in Specifying Nuclear Inclusion Formation in Polyglutamine Disease
2001
Modulating huntingtin half‐life alters polyglutamine‐dependent aggregate formation and cell toxicity
2004
Structural Bases of Desensitization in AMPA Receptor-Auxiliary Subunit Complexes
2017 StandoutNobel
Rapamycin and mTOR-independent autophagy inducers ameliorate toxicity of polyglutamine-expanded huntingtin and related proteinopathies
2008
Inhibition of Calpain Cleavage of Huntingtin Reduces Toxicity
2004
Huntington disease: new insights on the role of huntingtin cleavage
2000
Huntington’s disease: how does huntingtin, an anti-apoptotic protein, become toxic?
2004
Caspases and neurodegeneration: on the cutting edge of new therapeutic approaches
2000
Selective Neuronal Degeneration in Huntington's Disease
2006
Neurodegenerative disease and adult neurogenesis
2011
Three-Dimensional Structure of the Complexin/SNARE Complex
2002 StandoutNobel
The Neuropathology of Huntington’s Disease
2014
Huntingtin interacts with REST/NRSF to modulate the transcription of NRSE-controlled neuronal genes
2003
Inhibition of Papillomavirus Protein Function in Cervical Cancer Cells by Intrabody Targeting
2005 StandoutNobel
Transcriptional changes in Huntington disease identified using genome-wide expression profiling and cross-platform analysis
2010
Age-Associated mRNA and miRNA Expression Changes in the Blood-Brain Barrier
2019 StandoutNobel
Huntingtin Aggregate-Associated Axonal Degeneration is an Early Pathological Event in Huntington's Disease Mice
2001
Applications of the Morris water maze in the study of learning and memory
2001 Standout
Mechanisms of transcriptional dysregulation in Huntington's disease
2003
Caspase Cleavage of Mutant Huntingtin Precedes Neurodegeneration in Huntington's Disease
2002
Requirement of an intact microtubule cytoskeleton for aggregation and inclusion body formation by a mutant huntingtin fragment
2002
Abnormal Synaptic Plasticity and Impaired Spatial Cognition in Mice Transgenic for Exon 1 of the Human Huntington's Disease Mutation
2000
Huntington's disease: from pathology and genetics to potential therapies
2008
Insights from Mouse Models into the Molecular Basis of Neurodegeneration
2000
Lentiviral-Mediated Delivery of Mutant Huntingtin in the Striatum of Rats Induces a Selective Neuropathology Modulated by Polyglutamine Repeat Size, Huntingtin Expression Levels, and Protein Length
2002
Human single-chain Fv intrabodies counteract in situ huntingtin aggregation in cellular models of Huntington's disease
2001
Sox2deficiency causes neurodegeneration and impaired neurogenesis in the adult mouse brain
2004
Transcriptional dysregulation in Huntington’s disease
2000
SCA-12: Tremor with cerebellar and cortical atrophy is associated with a CAG repeat expansion
2001
Expanded CAG repeats in exon 1 of the Huntington's disease gene stimulate dopamine-mediated striatal neuron autophagy and degeneration
2001
Selective Discrimination Learning Impairments in Mice Expressing the Human Huntington's Disease Mutation
1999
Disruption of Axonal Transport by Loss of Huntingtin or Expression of Pathogenic PolyQ Proteins in Drosophila
2003
Tissue-Specific Proteolysis of Huntingtin (htt) in Human Brain: Evidence of Enhanced Levels of N- and C-Terminal htt Fragments in Huntington's Disease Striatum
2001
Mechanisms of Endocytosis
2009 Standout
Mutant huntingtin activates Nrf2-responsive genes and impairs dopamine synthesis in a PC12 model of Huntington's disease
2008
Regulation of Mammalian Autophagy in Physiology and Pathophysiology
2010 Standout
Disturbed Ca2+signaling and apoptosis of medium spiny neurons in Huntington's disease
2005
Muscarinic Acetylcholine Receptor Knockout Mice: Novel Phenotypes and Clinical Implications
2004
Works of Laure Jamot being referenced
A YAC Mouse Model for Huntington’s Disease with Full-Length Mutant Huntingtin, Cytoplasmic Toxicity, and Selective Striatal Neurodegeneration
1999
Dysfunction of the Cholesterol Biosynthetic Pathway in Huntington's Disease
2005
Increased drinking in mutant mice with truncated M5 muscarinic receptor genes
2002
Prenatal exposure to alcohol does not affect radial maze learning and hippocampal mossy fiber sizes in three inbred strains of mouse
2005
Neuronal and behavioral differences between Mus musculus domesticus (C57BL/6JBy) and Mus musculus castaneus (CAST/Ei)
1998
Hippocampal mossy fiber distributions in mice selected for aggression
1994
SCA12 is a rare locus for autosomal dominant cerebellar ataxia: A study of an Indian family
2001