Citation Impact
Citing Papers
rMATS: Robust and flexible detection of differential alternative splicing from replicate RNA-Seq data
2014 Standout
Human Induced Pluripotent Stem Cells Free of Vector and Transgene Sequences
2009 StandoutScience
High-Resolution Crystal Structure of an Engineered Human β 2 -Adrenergic G Protein–Coupled Receptor
2007 StandoutScienceNobel
Lysine Acetylation Targets Protein Complexes and Co-Regulates Major Cellular Functions
2009 StandoutScience
Intravenous Administration of Self-complementary AAV9 Enables Transgene Delivery to Adult Motor Neurons
2009
The EGLN-HIF O 2 -Sensing System: Multiple Inputs and Feedbacks
2017 StandoutNobel
Rapid identification of functionally critical amino acids in a G protein–coupled receptor
2007
Generation of Human Melanocytes from Induced Pluripotent Stem Cells
2011 StandoutNobel
G protein coupled receptor structure and activation
2006 StandoutNobel
A Comparison of Brain Gene Expression Levels in Domesticated and Wild Animals
2012 StandoutNobel
Mechanisms Underlying Inflammation in Neurodegeneration
2010 Standout
Structure of rhodopsin and the metarhodopsin I photointermediate
2005
Antisense Masking of an hnRNP A1/A2 Intronic Splicing Silencer Corrects SMN2 Splicing in Transgenic Mice
2008
Extracellular Vesicle RNA: A Universal Mediator of Microbial Communication?
2018 StandoutNobel
Telomere dysfunction in ageing and age-related diseases
2022
The Nuclear-Retained Noncoding RNA MALAT1 Regulates Alternative Splicing by Modulating SR Splicing Factor Phosphorylation
2010 Standout
The Spliceosome: Design Principles of a Dynamic RNP Machine
2009 Standout
Modeling familial Alzheimer's disease with induced pluripotent stem cells
2011 StandoutNobel
RNA-based recognition and targeting: sowing the seeds of specificity
2017 StandoutNobel
Constructing and Deconstructing Stem Cell Models of Neurological Disease
2011
Hallmarks of aging: An expanding universe
2023 Standout
Gut microbiota metabolism of dietary fiber influences allergic airway disease and hematopoiesis
2014 Standout
Quantifying Ligand Bias at Seven-Transmembrane Receptors
2011 StandoutNobel
The Science of Stroke: Mechanisms in Search of Treatments
2010 Standout
Genome-Scale CRISPR-Mediated Control of Gene Repression and Activation
2014 Standout
Immunogenicity of induced pluripotent stem cells
2011 StandoutNature
Rapid Single-Step Induction of Functional Neurons from Human Pluripotent Stem Cells
2013 StandoutNobel
Treatment of infantile-onset spinal muscular atrophy with nusinersen: a phase 2, open-label, dose-escalation study
2016 Standout
The splicing machinery is a genetic modifier of disease severity
2005
Identification of an Agonist-induced Conformational Change Occurring Adjacent to the Ligand-binding Pocket of the M3 Muscarinic Acetylcholine Receptor
2005
Structure-based drug screening for G-protein-coupled receptors
2012 StandoutNobel
Genotype–phenotype studies in infantile spinal muscular atrophy (SMA) type I in Germany: implications for clinical trials and genetic counselling
2009
Multiple Residues in the Second Extracellular Loop Are Critical for M3 Muscarinic Acetylcholine Receptor Activation
2007
RNA and Disease
2009
A new era of GPCR structural and chemical biology
2012 StandoutNobel
In vitro pharmacologic testing using human induced pluripotent stem cell-derived cardiomyocytes
2009 StandoutNobel
Glucose-Neopentyl Glycol (GNG) amphiphiles for membrane protein study
2012 StandoutNobel
Induced pluripotent stem cells and reprogramming: seeing the science through the hype
2009 StandoutNobel
Therapeutic application of histone deacetylase inhibitors for central nervous system disorders
2008
Insights into RNA Biology from an Atlas of Mammalian mRNA-Binding Proteins
2012 Standout
Induced pluripotent stem cells from a spinal muscular atrophy patient
2008 Nature
Adeno-associated virus vector as a platform for gene therapy delivery
2019 Standout
Conformational changes involved in G-protein-coupled-receptor activation
2008
Defining roles of specific reactive oxygen species (ROS) in cell biology and physiology
2022 Standout
A Fresh Look at iPS Cells
2009 StandoutNobel
Genomic Rearrangements and Gene Copy-Number Alterations as a Cause of Nervous System Disorders
2006
The many roles of histone deacetylases in development and physiology: implications for disease and therapy
2008 Standout
Crystal structure of the µ-opioid receptor bound to a morphinan antagonist
2012 StandoutNatureNobel
N-Terminal T4 Lysozyme Fusion Facilitates Crystallization of a G Protein Coupled Receptor
2012 StandoutNobel
Oxidative stress in developmental brain disorders
2009
A New Class of Amphiphiles Bearing Rigid Hydrophobic Groups for Solubilization and Stabilization of Membrane Proteins
2012 StandoutNobel
The Noncoding RNA Revolution—Trashing Old Rules to Forge New Ones
2014 Standout
Structure of a β1-adrenergic G-protein-coupled receptor
2008 StandoutNatureNobel
Alternative Splicing: Therapeutic Target and Tool
2006
Structure and dynamics of the M3 muscarinic acetylcholine receptor
2012 StandoutNatureNobel
Parkinson's Disease Patient-Derived Induced Pluripotent Stem Cells Free of Viral Reprogramming Factors
2009 Standout
Natural history of denervation in SMA: Relation to age, SMN2 copy number, and function
2005
Trichostatin A increases SMN expression and survival in a mouse model of spinal muscular atrophy
2007
Hepatic Stellate Cells: Protean, Multifunctional, and Enigmatic Cells of the Liver
2008 Standout
Selective Inhibition of Hypoxia-Inducible Factor (HIF) Prolyl-Hydroxylase 1 Mediates Neuroprotection against Normoxic Oxidative Death via HIF- and CREB-Independent Pathways
2009 StandoutNobel
Small RNAs are modified with N-glycans and displayed on the surface of living cells
2021 StandoutNobel
The evolution of gene expression levels in mammalian organs
2011 StandoutNatureNobel
Identification of Orthosteric and Allosteric Site Mutations in M2 Muscarinic Acetylcholine Receptors That Contribute to Ligand-selective Signaling Bias
2010
The SR protein family of splicing factors: master regulators of gene expression
2008
Genetically Encoded Tools for Research of Cell Signaling and Metabolism under Brain Hypoxia
2020
Genomes in Focus: Development and Applications of CRISPR‐Cas9 Imaging Technologies
2017 StandoutNobel
Exceptional Evolutionary Divergence of Human Muscle and Brain Metabolomes Parallels Human Cognitive and Physical Uniqueness
2014 StandoutNobel
Recent Stem Cell Advances: Induced Pluripotent Stem Cells for Disease Modeling and Stem Cell–Based Regeneration
2010 StandoutNobel
A General Mechanism for Network-Dosage Compensation in Gene Circuits
2010 StandoutScienceNobel
Computational Modeling Approaches to Structure−Function Analysis of G Protein-Coupled Receptors
2005
Short-chain fatty acids enhance nuclear receptor activity through mitogen-activated protein kinase activation and histone deacetylase inhibition
2004
Neurons generated by direct conversion of fibroblasts reproduce synaptic phenotype caused by autism-associated neuroligin-3 mutation
2013 StandoutNobel
Update 1 of: Computational Modeling Approaches to Structure–Function Analysis of G Protein-Coupled Receptors
2011
Chemistry and Biology Of Multicomponent Reactions
2012 Standout
Works of Lars Brichta being referenced
In vitro and ex vivo evaluation of second‐generation histone deacetylase inhibitors for the treatment of spinal muscular atrophy
2006
Spinal Muscular Atrophy and Therapeutic Prospects
2006
Loss of SATB1 Induces p21-Dependent Cellular Senescence in Post-mitotic Dopaminergic Neurons
2019
Pronounced Conformational Changes following Agonist Activation of the M3 Muscarinic Acetylcholine Receptor
2005
Mildly affected patients with spinal muscular atrophy are partially protected by an increased SMN2 copy number
2006
The benzamide M344, a novel histone deacetylase inhibitor, significantly increases SMN2 RNA/protein levels in spinal muscular atrophy cells
2006
Dopamine metabolism by a monoamine oxidase mitochondrial shuttle activates the electron transport chain
2019
Valproic acid increases the SMN2 protein level: a well-known drug as a potential therapy for spinal muscular atrophy
2003
In vivo activation of SMN in spinal muscular atrophy carriers and patients treated with valproate
2006
An ~140-kb deletion associated with feline spinal muscular atrophy implies an essentialLIX1function for motor neuron survival
2006
Spinal Muscular Atrophy: From Gene to Therapy
2006