Citation Impact
Citing Papers
Targeting of Diacylglycerol Degradation to M1 Muscarinic Receptors by ß-Arrestins
2007 StandoutScienceNobel
The IκB-NF-κB Signaling Module: Temporal Control and Selective Gene Activation
2002 StandoutScienceNobel
In vivo imaging of hydrogen peroxide production in a murine tumor model with a chemoselective bioluminescent reporter
2010 StandoutNobel
Strategy for Dual-Analyte Luciferin Imaging: In Vivo Bioluminescence Detection of Hydrogen Peroxide and Caspase Activity in a Murine Model of Acute Inflammation
2013 StandoutNobel
Ceramide: an intracellular mediator of apopotosis and growth supression
1996
The metabolic life and times of a T‐cell
2010
Subcellular targeting by membrane lipids
2001
Structure of the TRPA1 ion channel suggests regulatory mechanisms
2015 StandoutNatureNobel
Activators and target genes of Rel/NF-κB transcription factors
1999 Standout
Proteins regulating Ras and its relatives
1993 StandoutNature
COPII-Coated Vesicle Formation Reconstituted with Purified Coat Proteins and Chemically Defined Liposomes
1998 StandoutNobel
Prostaglandin synthase 1 gene disruption in mice reduces arachidonic acid-induced inflammation and indomethacin-induced gastric ulceration
1995 StandoutNobel
Long-term uncoupling of chloride secretion from intracellular calcium levels by lns(3,4,5,6)P4
1994 StandoutNatureNobel
Differential Kinetic and Spatial Patterns of β-Arrestin and G Protein-mediated ERK Activation by the Angiotensin II Receptor
2004 StandoutNobel
Phosphorylation of Munc-18/n-Sec1/rbSec1 by Protein Kinase C
1996 StandoutNobel
A novel arachidonic acid-selective cytosolic PLA2 contains a Ca2+-dependent translocation domain with homology to PKC and GAP
1991 Standout
Dynamic Covalent Chemistry
2002 StandoutNobel
AKT/PKB Signaling: Navigating Downstream
2007 Standout
Methods for the analysis of inositol phosphates
1989
Pro-resolving lipid mediators are leads for resolution physiology
2014 StandoutNature
Distinct Mechanisms Mediate the Initial and Sustained Phases of Integrin-mediated Activation of the Raf/MEK/Mitogen-activated Protein Kinase Cascade
1998
Angiotensin II Receptor Pharmacology
1994
Activation of multiple signal transduction pathways by endothelin in cultured human vascular smooth muscle cells
1990
Interleukin-1 stimulates diacylglycerol production in T lymphocytes by a novel mechanism
1988
Cloning of a cDNA encoding a non-isopeptide-selective subtype of the endothelin receptor
1990 StandoutNature
Ceramide: an endogenous regulator of apoptosis and growth suppresion
1995
Ceramide Triggers Meiotic Cell Cycle Progression in Xenopus Oocytes.
1995
The Hallmarks of Cancer
2000 Standout
Human nutrition, the gut microbiome and the immune system
2011 StandoutNature
Requirement for ceramide-initiated SAPK/JNK signalling in stress-induced apoptosis
1996 StandoutNature
The Role of GTP-Binding Proteins in Signal Transduction: From the Sublimely Simple to the Conceptually Complex
1992 StandoutNobel
Phosphorylation of the Type 1A Angiotensin II Receptor by G Protein-coupled Receptor Kinases and Protein Kinase C
1996 StandoutNobel
Suppression of ceramide-mediated programmed cell death by sphingosine-1-phosphate
1996 StandoutNature
Paracrine Induction of HIF by Glutamate in Breast Cancer: EglN1 Senses Cysteine
2016 StandoutNobel
Phospholipase D in homogenates from HL-60 granulocytes: Implications of calcium and G protein control
1989
C2-domains, Structure and Function of a Universal Ca2+-binding Domain
1998 StandoutNobel
The Recruitment of Raf-1 to Membranes Is Mediated by Direct Interaction with Phosphatidic Acid and Is Independent of Association with Ras
2000
Phosphatidylcholine breakdown and signal transduction
1994
Structure of the first C2 domain of synaptotagmin I: A novel Ca2+/phospholipid-binding fold
1995 StandoutNobel
Inhibition of Carnitine Palmitoyltransferase I Augments Sphingolipid Synthesis and Palmitate-induced Apoptosis
1997 StandoutNobel
Prostaglandin synthase 2 gene disruption causes severe renal pathology in the mouse
1995 StandoutNobel
Identification of a Novel Ca2+-dependent, Phosphatidylethanolamine-hydrolyzing Phospholipase D in Yeast Bearing a Disruption in PLD1
1997
Quantitative reactivity profiling predicts functional cysteines in proteomes
2010 StandoutNatureNobel
Phosphoinositides in cell regulation and membrane dynamics
2006 StandoutNature
Phospholipase D2, a distinct phospholipase D isoform with novel regulatory properties that provokes cytoskeletal reorganization
1997
Formation of diacylglycerol by a phospholipase D-phosphatidate phosphatase pathway specific for phosphatidylcholine in endothelial cells
1988
Dysregulated synthesis of protectin D1 in eosinophils from patients with severe asthma
2012
Ceramide synthase mediates daunorubicin-induced apoptosis: An alternative mechanism for generating death signals
1995
Changes in bioactive lipids, alkylacylglycerol and ceramide, occur in HIV-infected cells
1992
Regulation of sn-1,2-diacylglycerol second-messenger formation in thrombin-stimulated human platelets. Potentiation by protein kinase C inhibitors
1990
Micelle-Encapsulated Quantum Dot-Porphyrin Assemblies as in Vivo Two-Photon Oxygen Sensors
2015 StandoutNobel
Bcl-2 interrupts the ceramide-mediated pathway of cell death.
1996
Molecular species analysis of a product of phospholipase D activation. Phosphatidylethanol is formed from phosphatidylcholine in phorbol ester- and bradykinin-stimulated PC12 cells.
1992
A neutral phospholipase D activity from rat brain synaptic plasma membranes. Identification and partial characterization.
1990
The Ca2(+)-sensitive cytosolic phospholipase A2 is a 100-kDa protein in human monoblast U937 cells.
1991
The mechanism of protein kinase C activation
1989
Expression cloning of an ATP receptor from mouse neuroblastoma cells.
1993 StandoutNobel
Leukocyte lipid body formation and eicosanoid generation: cyclooxygenase-independent inhibition by aspirin.
1996 StandoutNobel
Phospholipase D activation in a cell-free system from human neutrophils by phorbol 12-myristate 13-acetate and guanosine 5'-O-(3-thiotriphosphate). Activation is calcium dependent and requires protein factors in both the plasma membrane and cytosol.
1991
Phosphorylation and Regulation of Raf by Akt (Protein Kinase B)
1999 Science
A novel mechanism for acetylcholine to generate diacylglycerol in brain.
1990
Signaling through phosphatidylcholine breakdown.
1990
Bombesin stimulates distinct time-dependent changes in the sn-1,2-diradylglycerol molecular species profile from Swiss 3T3 fibroblasts as analysed by 3,5-dinitrobenzoyl derivatization and h.p.l.c. separation
1993
Role for ceramide as an endogenous mediator of Fas-induced cytotoxicity.
1995
Kinetic analysis of 1,2-diacylglycerol mass levels in cultured fibroblasts. Comparison of stimulation by alpha-thrombin and epidermal growth factor.
1988
Activation of phospholipase D by protein kinase C. Evidence for a phosphorylation-independent mechanism.
1992
Identification and characterization of a hormonally regulated form of phospholipase A2 in rat renal mesangial cells.
1988
ADP-ribosylation factor and phosphatidic acid levels in Golgi membranes during budding of coatomer-coated vesicles
1998 StandoutNobel
A self-assembling protein kinase C inhibitor.
1991
Intracellular Signaling by Hydrolysis of Phospholipids and Activation of Protein Kinase C
1992 StandoutScience
Hormonal stimulation of diacylglycerol formation in hepatocytes.
1989
Phosphatidylcholine Hydrolysis by Phospholipase D Determines Phosphatidate and Diglyceride Levels in Chemotactic Peptide-stimulated Human Neutrophils
1989
Mining the Thiol Proteome for Sulfenic Acid Modifications Reveals New Targets for Oxidation in Cells
2009
Regulation of Phospholipase D in HL-60 Granulocytes
1989
Molecular species analysis of mitogen-stimulated 1,2-diglycerides in fibroblasts. Comparison of alpha-thrombin, epidermal growth factor, and platelet-derived growth factor.
1990
Programmed Cell Death Induced by Ceramide
1993 StandoutScience
Orchestrating Redox Signaling Networks through Regulatory Cysteine Switches
2009
Redox signalling via the cellular thiolstat
2011
The regulation and cellular functions of phosphatidylcholine hydrolysis
1990
Functionally active targeting domain of the beta-adrenergic receptor kinase: an inhibitor of G beta gamma-mediated stimulation of type II adenylyl cyclase.
1994 StandoutNobel
Bipartite Ca 2+ -Binding Motif in C 2 Domains of Synaptotagmin and Protein Kinase C
1996 StandoutScienceNobel
Vasopressin induces V1 receptors to activate phosphatidylinositol- and phosphatidylcholine-specific phospholipase C and stimulates the release of arachidonic acid by at least two pathways in the smooth muscle cell line, A-10.
1988
Tyrosine phosphorylation is involved in receptor coupling to phospholipase D but not phospholipase C in the human neutrophil
1992
Functions of Ceramide in Coordinating Cellular Responses to Stress
1996 StandoutScience
Cysteine-Mediated Redox Signaling: Chemistry, Biology, and Tools for Discovery
2013
Integrin Signaling
1999 StandoutScience
Functional association between Arf and RalA in active phospholipase D complex
1998
The disaggregation theory of signal transduction revisited: further evidence that G proteins are multimeric and disaggregate to monomers when activated.
1993 StandoutNobel
Isolation and characterization of PKC-L, a new member of the protein kinase C-related gene family specifically expressed in lung, skin, and heart.
1991
Retinoblastoma gene product as a downstream target for a ceramide-dependent pathway of growth arrest.
1995
P2-Purinergic Agonists Stimulate Phosphodiesteratic Cleavage of Phosphatidylcholine in Endothelial Cells
1989
Activation of Protein Kinase C by Naturally Occurring Ether-linked Diglycerides
1989
Phosphatidylcholine breakdown in rat liver plasma membranes. Roles of guanine nucleotides and P2-purinergic agonists.
1987
Intracellular Ca2+ and protein kinase C interact to regulate alpha 1-adrenergic- and bradykinin receptor-stimulated phospholipase A2 activation in Madin-Darby canine kidney cells
1991
Studies and Perspectives of Protein Kinase C
1986 StandoutScience
1997 StandoutNobel
Cytoplasmic lipid bodies of neutrophils: formation induced by cis-unsaturated fatty acids and mediated by protein kinase C.
1991
Controlling the Physical and Biological Properties of Highly Fluorescent Aqueous Quantum Dots Using Block Copolymers of Different Size and Shape
2013
A single C2 domain from synaptotagmin I is sufficient for high affinity Ca2+/phospholipid binding.
1993 StandoutNobel
Synaptotagmin: a Calcium Sensor on the Synaptic Vesicle Surface
1992 StandoutScienceNobel
The tyrosine kinase activity of the epidermal-growth-factor receptor is necessary for phospholipase A2 activation
1990
A dendrimer-based platform for simultaneous dual fluorescence imaging of hydrogen peroxide and pH gradients produced in living cells
2011
Generation of Calcium Oscillations in Fibroblasts by Positive Feedback Between Calcium and IP 3
1991 StandoutScienceNobel
Complement receptor-mediated phagocytosis is associated with accumulation of phosphatidylcholine-derived diglyceride in human neutrophils. Involvement of phospholipase D and direct evidence for a positive feedback signal of protein kinase.
1992
Lipid activation of protein kinase C.
1991
Molecular cloning and expression of human Ca(2+)-sensitive cytosolic phospholipase A2
1991
Involvement of Protein Kinase C in Platelet-activating Factor-stimulated Diacylglycerol Accumulation in Murine Peritoneal Macrophages
1989
Molecular Species Analysis of 1,2-Diglycerides Stimulated by α-Thrombin in Cultured Fibroblasts
1989
Heterotrimeric G proteins in synaptoneurosome membranes are crosslinked by p-phenylenedimaleimide, yielding structures comparable in size to crosslinked tubulin and F-actin.
1992 StandoutNobel
Multiple calcium-mediated effector mechanisms regulate chloride secretory responses in T84-cells
1989
Signal Transduction through MAP Kinase Cascades
1998 Standout
Signal transduction via phosphatidylcholine cycles
1989
Synergistic action of diacylglycerol and unsaturated fatty acid for protein kinase C activation: its possible implications.
1991
Phospholipase A2 activation in human neutrophils. Differential actions of diacylglycerols and alkylacylglycerols in priming cells for stimulation by N-formyl-Met-Leu-Phe.
1988
Signal Transduction and Signal Modulation by Cell Adhesion Receptors: The Role of Integrins, Cadherins, Immunoglobulin-Cell Adhesion Molecules, and Selectins
1998
Dissociation of protein kinase C activation from phorbol ester-induced maturation of HL-60 leukemia cells.
1985
Evidence for a catalytic role of phospholipase A in phorbol diester- and zymosan-induced mobilization of arachidonic acid in mouse peritoneal macrophages
1986
Identification of an immediate early gene, pghs-B, whose protein product has prostaglandin synthase/cyclooxygenase activity.
1992
Expression of a mitogen-responsive gene encoding prostaglandin synthase is regulated by mRNA splicing.
1991
Attenuation of ceramide-induced apoptosis by diglyceride in human myeloid leukemia cells.
1994
Structure and mechanism of the G protein-coupled receptor kinases.
1993 StandoutNobel
TNF- and Cancer Therapy-Induced Apoptosis: Potentiation by Inhibition of NF-κB
1996 StandoutScience
Works of Larry W. Daniel being referenced
The Requirement of Reversible Cysteine Sulfenic Acid Formation for T Cell Activation and Function
2007
Synthesis and biological activity of novel quaternary ammonium derivatives of alkylglycerols as potent inhibitors of protein kinase C
1990
Raf-1 Kinase Possesses Distinct Binding Domains for Phosphatidylserine and Phosphatidic Acid
1996
Alkyl-linked diglycerides inhibit protein kinase C activation by diacylglycerols
1988
Stimulation of deacylation in Madin-Darby canine kidney cells. Specificity of deacylation and prostaglandin production in 12-O-tetradecanoylphorbol-13-acetate-treated cells.
1982
Choline-linked Phosphoglycerides
1989
Fluorescent and Affinity-Based Tools To Detect Cysteine Sulfenic Acid Formation in Proteins
2007
Phospholipase D hydrolysis of choline phosphoglycerides is selective for the alkyl-linked subclass of Madin-Darby canine kidney cells.
1993
5-Oxo-eicosatetraenoate is a broadly active, eosinophil-selective stimulus for human granulocytes.
1996
Source of arachidonic acid for prostaglandin synthesis in Madin-Darby canine kidney cells.
1981
Evidence of protein kinase C involvement in phorbol diester-stimulated arachidonic acid release and prostaglandin synthesis.
1987
1-beta-D-Arabinofuranosylcytosine stimulates ceramide and diglyceride formation in HL-60 cells.
1994
A novel mechanism of diglyceride formation. 12-O-tetradecanoylphorbol-13-acetate stimulates the cyclic breakdown and resynthesis of phosphatidylcholine.
1986
1-O-hexadecyl-2-acetyl-sn-glycerol stimulates differentiation of HL-60 human promyelocytic leukemia cells to macrophage-like cells
1984
Regulation of arachidonic acid metabolism in madin-darby canine kidney cells Comparison of A23187 and 12-O-tetradecanoyl-phorbol-13-acetate
1984
Identification of phosphatidylcholine-selective and phosphatidylinositol-selective phospholipases D in Madin-Darby canine kidney cells.
1992