Citation Impact
Citing Papers
Endogenous Markers of Two Separate Hypoxia Response Pathways (hypoxia inducible factor 2 alpha and carbonic anhydrase 9) Are Associated With Radiotherapy Failure in Head and Neck Cancer Patients Recruited in the CHART Randomized Trial
2006
Epigenetic Repression of DNA Mismatch Repair by Inflammation and Hypoxia in Inflammatory Bowel Disease–Associated Colorectal Cancer
2009 StandoutNobel
Hypoxia-induced resistance to anticancer drugs is associated with decreased senescence and requires hypoxia-inducible factor-1 activity
2008 StandoutNobel
Trapping of PARP1 and PARP2 by Clinical PARP Inhibitors
2012 Standout
Oxidative Stress
2017 Standout
Improved Recurrence-Free Survival with ARCON for Anemic Patients with Laryngeal Cancer
2014
Factors Associated With Severe Late Toxicity After Concurrent Chemoradiation for Locally Advanced Head and Neck Cancer: An RTOG Analysis
2008 Standout
Endogenous markers of hypoxia/anaerobic metabolism and anemia in primary colorectal cancer
2006
Sirtuins as regulators of metabolism and healthspan
2012 Standout
AMPK regulates energy expenditure by modulating NAD+ metabolism and SIRT1 activity
2009 StandoutNature
The prognostic value of the hypoxia markers CA IX and GLUT 1 and the cytokines VEGF and IL 6 in head and neck squamous cell carcinoma treated by radiotherapy ± chemotherapy
2005
Hypoxia-Inducible Factors and the Response to Hypoxic Stress
2010 Standout
Hypoxia-regulated carbonic anhydrase IX expression is associated with poor survival in patients with invasive breast cancer
2007
Head and neck squamous cell carcinoma
2020 Standout
Hypoxia — a key regulatory factor in tumour growth
2002 Standout
Tumor R2* is a prognostic indicator of acute radiotherapeutic response in rodent tumors
2004
Targeting hypoxia in cancer therapy
2011 Standout
Inhibition of Silencing and Accelerated Aging by Nicotinamide, a Putative Negative Regulator of Yeast Sir2 and Human SIRT1
2002
18F-EF5: A New PET Tracer for Imaging Hypoxia in Head and Neck Cancer
2008
Oxidative stress, inflammation, and cancer: How are they linked?
2010 Standout
The prognostic value of pimonidazole and tumour pO2 in human cervix carcinomas after radiation therapy: A prospective international multi-center study
2006
HIF-1 mediates adaptation to hypoxia by actively downregulating mitochondrial oxygen consumption
2006 Standout
Regulation of cancer cell metabolism by hypoxia-inducible factor 1
2008 StandoutNobel
Tumor hypoxia at the micro-regional level: clinical relevance and predictive value of exogenous and endogenous hypoxic cell markers
2003
Chemical Radiosensitizers for Use in Radiotherapy
2007
Hypoxia Regulates CD44 and Its Variant Isoforms through HIF-1α in Triple Negative Breast Cancer
2012 StandoutNobel
Overexpression of Intrinsic Hypoxia Markers HIF1α and CA-IX Predict for Local Recurrence in Stage T1-T2 Glottic Laryngeal Carcinoma Treated With Radiotherapy
2008
Drug penetration in solid tumours
2006 Standout
Lung Cancer
2008 Standout
Head and neck cancer
2008 Standout
HIF2α cooperates with RAS to promote lung tumorigenesis in mice
2009 StandoutNobel
The tumour microenvironment after radiotherapy: mechanisms of resistance and recurrence
2015 Standout
Accelerated Radiotherapy, Carbogen, and Nicotinamide (ARCON) in the Treatment of Advanced Bladder Cancer: Mature Results of a Phase II Nonrandomized Study
2008
Predicting outcomes in radiation oncology—multifactorial decision support systems
2012
Evaluation of the larynx for tumour recurrence by diffusion-weighted MRI after radiotherapy: initial experience in four cases
2006
Late toxicities after conventional radiation therapy alone for nasopharyngeal carcinoma
2012
The Therapeutic Potential of Poly(ADP-Ribose) Polymerase Inhibitors
2002 Standout
Nano based drug delivery systems: recent developments and future prospects
2018 Standout
Machine Learning methods for Quantitative Radiomic Biomarkers
2015 Standout
Exploiting tumour hypoxia in cancer treatment
2004 Standout
Endogenous Hypoxia Markers in Locally Advanced Cancers of the Uterine Cervix: Reality or Wishful Thinking?
2006
Tirapazamine causes vascular dysfunction in HCT-116 tumour xenografts
2006
Regulation of cancer cell metabolism
2011 Standout
Nasopharyngeal carcinoma
2015 Standout
Assessment of tumour hypoxia for prediction of response to therapy and cancer prognosis
2009
Hypoxia in cancer: significance and impact on clinical outcome
2007 Standout
The pathobiology of mucositis
2004 Standout
Confluence-dependent resistance to doxorubicin in human MDA-MB-231 breast carcinoma cells requires hypoxia-inducible factor-1 activity
2006
GLUT1 and CAIX as intrinsic markers of hypoxia in bladder cancer: relationship with vascularity and proliferation as predictors of outcome of ARCON
2003
Carbonic anhydrases: novel therapeutic applications for inhibitors and activators
2008 Standout
Hypoxia in larynx carcinomas assessed by pimonidazole binding and the value of CA-IX and vascularity as surrogate markers of hypoxia
2009
The Hypoxic Tumour Microenvironment, Patient Selection and Hypoxia-modifying Treatments
2007
Hypoxia: Importance in tumor biology, noninvasive measurement by imaging, and value of its measurement in the management of cancer therapy
2006
MicroRNA therapeutics: towards a new era for the management of cancer and other diseases
2017 Standout
Targeting the hypoxia-inducible factor (HIF) pathway in cancer
2009
Radiation-/hypoxia-induced solid tumor metastasis and regrowth inhibited by hypoxia-specific upconversion nanoradiosensitizer
2015
Radiation chemistry comes before radiation biology
2009
Individualization of cancer treatment from radiotherapy perspective
2012
PET of Hypoxia with89Zr-Labeled cG250-F(ab′)2in Head and Neck Tumors
2010
ARCON: accelerated radiotherapy with carbogen and nicotinamide in head and neck squamous cell carcinomas. The experience of the Co-operative Group of Radiotherapy of the European Organization for Research and Treatment of Cancer (EORTC)
2000
Immunohistochemical detection of osteopontin in advanced head-and-neck cancer: Prognostic role and correlation with oxygen electrode measurements, hypoxia-inducible-factor-1α-related markers, and hemoglobin levels
2006
Recombinant human erythropoietin increases the radiosensitivity of xenografted human tumours in anaemic nude mice
2001
The prognostic value of endogenous hypoxia-related markers for head and neck squamous cell carcinomas treated with ARCON
2006
Exploring the role of cancer stem cells in radioresistance
2008
Differentiation-associated staining with anti-pimonidazole antibodies in head and neck tumors
2004
Molecular mechanisms of carbonic anhydrase IX‐mediated pH regulation under hypoxia
2008 StandoutNobel
Tumor metastasis: mechanistic insights and clinical challenges
2006 Standout
Hypoxic Tumors and Their Effect on Immune Cells and Cancer Therapy
2010
Tumor oxygenation status as a prognostic marker
2004
Clinical Outcome and Tumour Microenvironmental Effects of Accelerated Radiotherapy with Carbogen and Nicotinamide
1999
Tumor Hypoxia: Definitions and Current Clinical, Biologic, and Molecular Aspects
2001 Standout
Hypoxic tumor cell radiosensitization through nitric oxide
2008
Reversible Off–On Fluorescence Probe for Hypoxia and Imaging of Hypoxia–Normoxia Cycles in Live Cells
2012
Imaging the hypoxia surrogate marker CA IX requires expression and catalytic activity for binding fluorescent sulfonamide inhibitors
2007
Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan
2003 StandoutNature
Decoding tumour phenotype by noninvasive imaging using a quantitative radiomics approach
2014 Standout
Hypoxic modification of radiotherapy in squamous cell carcinoma of the head and neck – A systematic review and meta-analysis
2011
Radiomics: the bridge between medical imaging and personalized medicine
2017 Standout
Prognostic significance of tumor oxygenation in humans
2003
Altered Fractionation and/or Adjuvant Chemotherapy in Definitive Irradiation of Squamous Cell Carcinoma of the Head and Neck
2003
Defining the role of hypoxia-inducible factor 1 in cancer biology and therapeutics
2009 StandoutNobel
Evaluation of HIF-1 inhibitors as anticancer agents
2007 StandoutNobel
Drug Resistance and the Solid Tumor Microenvironment
2007 Standout
The role of elective neck dissection in early stage buccal cancer
2014
Acute Hypoxia Enhances Spontaneous Lymph Node Metastasis in an Orthotopic Murine Model of Human Cervical Carcinoma
2004
Photothermal therapy and photoacoustic imaging via nanotheranostics in fighting cancer
2018 Standout
A New Prodrug-Derived Ratiometric Fluorescent Probe for Hypoxia: High Selectivity of Nitroreductase and Imaging in Tumor Cell
2011
Digoxin and other cardiac glycosides inhibit HIF-1α synthesis and block tumor growth
2008 StandoutNobel
Accelerated Radiotherapy With Carbogen and Nicotinamide for Laryngeal Cancer: Results of a Phase III Randomized Trial
2012
Chronic Hypoxia Decreases Synthesis of Homologous Recombination Proteins to Offset Chemoresistance and Radioresistance
2008
Luminescent Chemodosimeters for Bioimaging
2012 Standout
Expression of HIF-1α, CA IX, VEGF, and MMP-9 in surgically resected non-small cell lung cancer
2005
Selective Killing of Hypoxia-Inducible Factor-1–Active Cells Improves Survival in a Mouse Model of Invasive and Metastatic Pancreatic Cancer
2009 StandoutNobel
Overcoming Physiologic Barriers to Cancer Treatment by Molecularly Targeting the Tumor Microenvironment
2006
Reversible Near-Infrared Fluorescent Probe Introducing Tellurium to Mimetic Glutathione Peroxidase for Monitoring the Redox Cycles between Peroxynitrite and Glutathione in Vivo
2013 Standout
Nanotechnology for Multimodal Synergistic Cancer Therapy
2017 Standout
Oxygen Sensing, Hypoxia-Inducible Factors, and Disease Pathophysiology
2013 StandoutNobel
Radiosensitization by the poly(ADP-ribose) polymerase inhibitor 4-amino-1,8-naphthalimide is specific of the S phase of the cell cycle and involves arrest of DNA synthesis
2006
Elective versus Therapeutic Neck Dissection in Node-Negative Oral Cancer
2015 Standout
Hypoxia-Inducible Factor 1α Expression as an Intrinsic Marker of Hypoxia
2004
Comparative Measurements of Hypoxia in Human Brain Tumors Using Needle Electrodes and EF5 Binding
2004
Novel Resveratrol and 5-Fluorouracil Coencapsulated in PEGylated Nanoliposomes Improve Chemotherapeutic Efficacy of Combination against Head and Neck Squamous Cell Carcinoma
2014
Prognostic Significance of [18F]-Misonidazole Positron Emission Tomography–Detected Tumor Hypoxia in Patients With Advanced Head and Neck Cancer Randomly Assigned to Chemoradiation With or Without Tirapazamine: A Substudy of Trans-Tasman Radiation Oncology Group Study 98.02
2006
Prognostic significance of HIF-2.ALPHA. expression on tumor infiltrating macrophages in patients with uterine cervical cancer undergoing radiotherapy
2008
HPV, hypoxia and radiation response in head and neck cancer
2018
Use of Larynx-Preservation Strategies in the Treatment of Laryngeal Cancer: American Society of Clinical Oncology Clinical Practice Guideline Update
2017
Diffusion-Weighted MRI in the Body: Applications and Challenges in Oncology
2007 Standout
Cancer Stem Cells: Targets and Potential Biomarkers for Radiotherapy
2011
Oral Sequelae of Head and Neck Radiotherapy
2003 Standout
Carbonic anhydrase IX expression, hypoxia, and prognosis in patients with uterine cervical carcinomas.
2003
Multimodality imaging of hypoxia in preclinical settings.
2010
Characterization and validation of noninvasive oxygen tension measurements in human glioma xenografts by 19F-MR relaxometry
1999
Works of L.A.M. Pop being referenced
Acute Toxicity Profile and Compliance to Accelerated Radiotherapy Plus Carbogen and Nicotinamide for Clinical Stage T2–4 Laryngeal Cancer: Results of a Phase III Randomized Trial
2011
ARCON: experience in 215 patients with advanced head-and-neck cancer
2002
Long-Term Outcome and Morbidity After Treatment With Accelerated Radiotherapy and Weekly Cisplatin for Locally Advanced Head-and-Neck Cancer: Results of a Multidisciplinary Late Morbidity Clinic
2010
Accelerated radiotherapy with carbogen and nicotinamide (ARCON) for laryngeal cancer
1998
External Beam Radiotherapy With Endocavitary Boost for Nasopharyngeal Cancer: Treatment Results and Late Toxicity After Extended Follow-Up
2010
Oxygen-modifying treatment with ARCON reduces the prognostic significance of hemoglobin in squamous cell carcinoma of the head and neck
2005
Evaluation of treatment results of squamous cell carcinoma of the buccal mucosa
1989
Pimonidazole binding and tumor vascularity predict for treatment outcome in head and neck cancer.
2002